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List of works by Andre Boonstra

1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells.

scientific article published in November 2001

A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B

scientific article published on 02 July 2018

A mutation in the progesterone receptor predisposes to HEV infection in HIV-positive patients

scientific article published on 28 December 2017

Abundant numbers of regulatory T cells localize to the liver of chronic hepatitis C infected patients and limit the extent of fibrosis

scientific article published on 24 December 2009

Alpha-galactosylceramide in chronic hepatitis B infection: results from a randomized placebo-controlled Phase I/II trial.

scientific article published on January 2009

Analysis of the transcriptome and immune function of monocytes during IFNα-based therapy in chronic HCV revealed induction of TLR7 responsiveness

scientific article published on 9 July 2014

Assessment of the effect of ribavirin on myeloid and plasmacytoid dendritic cells during interferon-based therapy of chronic hepatitis B patients

scientific article published on 20 July 2012

Association between liver fibrosis and hepatitis E seroprevalence among HIV-positive individuals in Nepal

article

Biochemical measures and frailty in people with intellectual disabilities

scientific article

CD4+ CXCR5+ T cells in chronic HCV infection produce less IL-21, yet are efficient at supporting B cell responses

scientific article published on 2 October 2014

Characterization of the “a” determinant region of the hepatitis B virus genome in Iranian patients at different clinical phases of chronic infection.

scientific article

Continuous interferon-α2b infusion in combination with ribavirin for chronic hepatitis C in treatment-experienced patients

scientific article published on 13 December 2011

Controversy on the role of FoxP3⁺ regulatory T cells in fibrogenesis in chronic hepatitis C virus infections

scientific article published on 14 September 2013

Decreased pro-inflammatory immune responses during recurrent acute HCV infections in HIV co-infected patients

scientific article published on 8 June 2017

Differential expression of innate immune response genes in clinical phases of chronic hepatitis B infection

scientific article published on 20 February 2017

Differential ultraviolet-B-induced immunomodulation in XPA, XPC, and CSB DNA repair-deficient mice

scientific article published on 01 July 2001

Early morbidity encountered in the dietary-related mouse model of Barrett's esophagus: a question of zinc?

scientific article

Endogenous IFNλ in viral hepatitis patients

scientific article published on 16 January 2014

Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung

scientific article

Erythropoietin administration suppresses human monocyte function in vitro and during therapy-induced anemia in HCV patients

scientific article published on 11 April 2013

Evaluation of IL-28B polymorphisms and serum IP-10 in hepatitis C infected chimpanzees

scientific article

Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation ⬇️

scientific article

Focus on the liver: Host-virus interactions in HBV.

scientific article published on 13 February 2017

Follicular T helper cells and humoral reactivity in kidney transplant patients

scientific article

Frequencies of Circulating MAIT Cells Are Diminished in Chronic HCV, HIV and HCV/HIV Co-Infection and Do Not Recover during Therapy

scientific article

Gene expression profiling of human tissue-resident immune cells: Comparing blood and liver

article

Gene expression profiling to predict and assess the consequences of therapy-induced virus eradication in chronic hepatitis C virus infection

scientific article

Hepatitis B core-related antigen levels are associated with response to entecavir and peginterferon add-on therapy in hepatitis B e antigen-positive chronic hepatitis B patients

scientific article

Hepatitis B core-related antigen levels predict recurrence-free survival in patients with HBV-associated early-stage hepatocellular carcinoma: results from a Dutch long-term follow-up study

scientific article published on 01 September 2020

Hepatitis B core-related antigen monitoring during peginterferon alfa treatment for HBeAg-negative chronic hepatitis B

scientific article published on 04 August 2019

Hepatitis B virus infection and the immune response: The big questions

scientific article

Hepatitis C treatment and liver cancer recurrence: cause for concern?

scientific article published on 12 January 2017

Hepatitis E Virus (HEV) Genotype 3 Infection of Human Liver Chimeric Mice as a Model for Chronic HEV Infection

scientific article published on 17 February 2016

Host and viral factors associated with serum hepatitis B virus RNA levels among patients in need for treatment.

scientific article published on 7 March 2018

IFN-λ is able to augment TLR-mediated activation and subsequent function of primary human B cells

scientific article published on 30 June 2015

IFN-λ-mediated IL-12 production in macrophages induces IFN-γ production in human NK cells

scientific article published on 10 November 2014

IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

scientific article

IL-29 and IFNα differ in their ability to modulate IL-12 production by TLR-activated human macrophages and exhibit differential regulation of the IFNγ receptor expression

scientific article published on 29 December 2010

ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection

scientific article

Immune activation in prolonged cART-suppressed HIV patients is comparable to that of healthy controls.

scientific article published on 20 June 2017

Immune mechanisms of vaccine induced protection against chronic hepatitis C virus infection in chimpanzees.

scientific article

Immunological Analysis During Interferon-Free Therapy for Chronic Hepatitis C Virus Infection Reveals Modulation of the Natural Killer Cell Compartment

scientific article published on 28 July 2015

Immunological biomarker discovery in cure regimens for chronic hepatitis B virus infection

scientific article published on 05 March 2022

Immunology of hepatitis B and hepatitis C virus infections.

scientific article published on January 2008

Immunology of hepatitis C virus infections.

scientific article published on August 2012

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

scientific article

Inflammatory monocytes recruited to the liver within 24 hours after virus-induced inflammation resemble Kupffer cells but are functionally distinct

scientific article

Inhibitory receptor molecules in chronic hepatitis B and C infections: novel targets for immunotherapy?

scientific article published on March 2014

Interferon-alpha treatment rapidly clears Hepatitis E virus infection in humanized mice

scientific article published on 15 August 2017

Intrahepatic natural killer cell activation, but not function, is associated with HBsAg levels in patients with HBeAg-negative chronic hepatitis B.

scientific article published on 25 July 2013

Intrahepatic regulatory T cells are phenotypically distinct from their peripheral counterparts in chronic HBV patients.

scientific article

Kupffer cells express a unique combination of phenotypic and functional characteristics compared with splenic and peritoneal macrophages.

scientific article

Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function.

scientific article published on 31 October 2014

Levels of Cytokines in Serum Associate With Development of Hepatocellular Carcinoma in Patients With HCV Infection Treated With Direct-acting Antivirals.

scientific article published in November 2017

Liver Monocytes and Kupffer Cells Remain Transcriptionally Distinct during Chronic Viral Infection

scientific article

Longitudinal analysis of peripheral and intrahepatic NK cells in chronic HCV patients during antiviral therapy.

scientific article published on 9 September 2015

Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals.

scientific article published in December 2006

Malaria infection changes the ability of splenic dendritic cell populations to stimulate antigen-specific T cells

scientific article

Mechanisms of Accelerated Liver Fibrosis Progression during HIV Infection.

scientific article

Metabolic characterization of the natural progression of chronic hepatitis B.

scientific article published on 10 June 2016

Modulation of Toll-like receptor 9 expression on monocytes of viral hepatitis patients

scientific article published on 10 September 2014

Modulation of dendritic cell function by persistent viruses.

scientific article published on 25 September 2008

Monocytes from chronic HBV patients react in vitro to HBsAg and TLR by producing cytokines irrespective of stage of disease

scientific article

Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology

article by Carine Asselin-Paturel et al published 19 November 2001 in Nature Immunology

Mucosal-associated invariant T (MAIT) cells are more activated in chronic hepatitis B, but not depleted in blood: reversal by antiviral therapy

scientific article published on 23 August 2017

Mucosal-associated invariant T-cell frequency and function in blood and liver of HCV mono- and HCV/HIV co-infected patients with advanced fibrosis.

scientific article

NK cell phenotypic and functional shifts coincide with specific clinical phases in the natural history of chronic HBV infection

scientific article published on 13 January 2017

NK cells in self-limited HCV infection exhibit a more extensively differentiated, but not memory-like, repertoire.

scientific article published on 17 April 2017

Natural killer cell activity and function in chronic HCV-infected patients during peg interferon and ribavirin: early effects of active substance use.

scientific article published on 2 January 2013

Negative regulation of hepatitis C virus specific immunity is highly heterogeneous and modulated by pegylated interferon-alpha/ribavirin therapy

scientific article

PI3K-PKB hyperactivation augments human plasmacytoid dendritic cell development and function.

scientific article

Persistent metabolic changes in HIV-infected patients during the first year of combination antiretroviral therapy

scientific article published in Scientific Reports

Polymorphisms of HLA-DP are associated with response to peginterferon in Caucasian patients with chronic hepatitis B.

scientific article published on 11 August 2014

Potent immune activation in chronic hepatitis C patients upon administration of an oral inducer of endogenous interferons that acts via Toll-like receptor 7

article

Precore and core promoter mutants are associated with higher HBeAg seroconversion but low disease remission rates in HBV patients treated with nucleos(t)ide analogues

scientific article published on 05 December 2012

Prediction of long-term clinical outcome in a diverse chronic hepatitis B population: Role of the PAGE-B score.

scientific article published on 24 May 2017

Prevalence and risk of hepatitis E virus infection in the HIV population of Nepal

scientific article published on 21 November 2017

Randomised clinical trial: anti-viral activity of ANA773, an oral inducer of endogenous interferons acting via TLR7, in chronic HCV.

scientific article

Re-evaluation of hepatitis B virus clinical phases by systems biology identifies unappreciated roles for the innate immune response and B cells

scientific article published on 27 April 2015

Relationship between hepatitis B core-related antigen levels and sustained HBeAg seroconversion in patients treated with nucleo(s)tide analogues

scientific article published on 16 April 2019

Restoration of TLR3-activated myeloid dendritic cell activity leads to improved natural killer cell function in chronic hepatitis B virus infection

scientific article published on 8 February 2012

Retention of CD4+ CD25+ FoxP3+ regulatory T cells in the liver after therapy-induced hepatitis C virus eradication in humans

scientific article published on 30 March 2011

Role for IL-10 in inducing functional impairment of monocytes upon TLR4 ligation in patients with chronic HCV infections

scientific article published on 8 March 2011

Role of T cell immunity in hepatitis C virus infections.

scientific article published on 02 June 2013

Role of microbial translocation in soluble CD14 up-regulation in HIV-, but not in HCV-, infected chimpanzees

scientific article

Sensitive detection of hepatocellular injury in chronic hepatitis C patients with circulating hepatocyte-derived microRNA-122.

scientific article published on 27 August 2012

Serum hepatitis B virus RNA predicts response to peginterferon treatment in HBeAg-positive chronic hepatitis B

scientific article published on 12 February 2020

Serum levels of interferon-gamma-inducible protein 10 and response to peginterferon therapy in HBeAg-positive chronic hepatitis B.

scientific article

Similar frequencies, phenotype and activation status of intrahepatic NK cells in chronic HBV patients after long-term treatment with tenofovir disoproxil fumarate (TDF).

scientific article

Spontaneous and natural cytotoxicity receptor-mediated cytotoxicity are effector functions of distinct natural killer subsets in hepatitis C virus-infected chimpanzees

scientific article

Sustained virologic response after therapy with the HCV protease inhibitor narlaprevir in combination with peginterferon and ribavirin is durable through long-term follow-up.

scientific article published on 7 January 2013

T-cell responses at baseline and during therapy with peginterferon-alpha and ribavirin are not associated with outcome in chronic hepatitis C infected patients.

scientific article published on 12 June 2010

TLR7 polymorphism, sex and chronic HBV infection influence plasmacytoid DC maturation by TLR7 ligands

scientific article published on 28 June 2018

The DNA-binding factor Ctcf critically controls gene expression in macrophages.

scientific article published on 9 September 2013

The Intrahepatic T Cell Compartment Does Not Normalize Years After Therapy-Induced Hepatitis C Virus Eradication

scientific article published on 30 January 2015

The Path to Cancer and Back: Immune Modulation During Hepatitis C Virus Infection, Progression to Fibrosis and Cancer, and Unexpected Roles of New Antivirals.

scientific article published on 30 December 2016

The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor

scientific article

The impact of PNPLA3 (rs738409 C>G) polymorphisms on liver histology and long-term clinical outcome in chronic hepatitis B patients

scientific article published on 24 October 2014

The membrane-bound O-acyltransferase domain-containing 7 variant rs641738 increases inflammation and fibrosis in chronic hepatitis B.

scientific article published on 20 January 2017

The response to TLR ligation of human CD16⁺CD14⁻ monocytes is weakly modulated as a consequence of persistent infection with the hepatitis C virus

scientific article published on 30 April 2011

The role of Kupffer cells in hepatitis B and hepatitis C virus infections.

scientific article published on 04 May 2014

The role of cytokines in ultraviolet-B induced immunosuppression.

scientific article published on June 1997

Type I and III interferons enhance IL-10R expression on human monocytes and macrophages, resulting in IL-10-mediated suppression of TLR-induced IL-12

scientific article published on 13 July 2012

Type I interferon dependence of plasmacytoid dendritic cell activation and migration.

scientific article

UV exposure alters respiratory allergic responses in mice

scientific article published on 01 August 2000

UVB irradiation modulates systemic immune responses by affecting cytokine production of antigen-presenting cells

scientific article published on 01 November 2000

Understanding IFNλ in rheumatoid arthritis.

scientific article published on 21 January 2014

Unique intrahepatic transcriptomics profiles discriminate the clinical phases of a chronic HBV infection.

scientific article

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