List of works by Timothy R. Lezon

A Quantitative Systems Pharmacology Approach to Infer Pathways Involved in Complex Disease Phenotypes

scientific article published on 01 January 2018

Biologically Relevant Heterogeneity: Metrics and Practical Insights

scientific article published on 06 January 2017

Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington's Disease Model through the Application of Quantitative Systems Pharmacology.

scientific article published on 19 December 2017

Evol and ProDy for bridging protein sequence evolution and structural dynamics

scientific article

Geometry of proteins: hydrogen bonding, sterics, and marginally compact tubes.

scientific article

Global motions of the nuclear pore complex: insights from elastic network models

scientific article

Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery

scientific article (publication date: 2014)

Modeling global changes induced by local perturbations to the HIV-1 capsid.

scientific article

Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images.

scientific article published in November 2017

Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers.

scientific article published on 29 November 2016

Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways.

scientific article published on 30 June 2016

Recognition of coarse-grained protein tertiary structure

scientific article

The effects of rigid motions on elastic network model force constants

scientific article published on 7 January 2012

Using entropy maximization to understand the determinants of structural dynamics beyond native contact topology

scientific article