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List of works by Salvador Ventura

A fast and specific method to screen for intracellular amyloid inhibitors using bacterial model systems

scientific article published on 31 October 2015

A pyrene-inhibitor fluorescent probe with large Stokes shift for the staining of Aβ, α-synuclein, and amylin amyloid fibrils as well as amyloid-containing Staphylococcus aureus biofilms

scientific article published on 09 November 2018

A single cysteine post-translational oxidation suffices to compromise globular proteins kinetic stability and promote amyloid formation.

scientific article published on 31 October 2017

AGGRESCAN3D (A3D): server for prediction of aggregation properties of protein structures.

scientific article

AGGRESCAN3D: Toward the Prediction of the Aggregation Propensities of Protein Structures

scientific article

AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides

scientific article published on 27 February 2007

AGGRESCAN: method, application, and perspectives for drug design

scientific article published in January 2012

AMYCO: evaluation of mutational impact on prion-like proteins aggregation propensity

scientific article published on 14 January 2019

About targets and causes in protein folding

scientific article published on 9 January 2013

Advances in the prediction of protein aggregation propensity

scientific article

Aggregation as bacterial inclusion bodies does not imply inactivation of enzymes and fluorescent proteins

scientific article

Aggregation of the neuroblastoma-associated mutant (S120G) of the human nucleoside diphosphate kinase-A/NM23-H1 into amyloid fibrils

scientific article published on 12 April 2011

Aggregation propensity of neuronal receptors: potential implications in neurodegenerative disorders.

scientific article published on September 2015

Aggrescan3D (A3D) 2.0: prediction and engineering of protein solubility

scientific article published on 01 July 2019

Aggrescan3D standalone package for structure-based prediction of protein aggregation properties

scientific article published on 01 October 2019

Amyloid cores in prion domains: Key regulators for prion conformational conversion.

scientific article published in January 2017

Amyloid fibril formation by a partially structured intermediate state of alpha-chymotrypsin.

scientific article

Amyloid formation by human carboxypeptidase D transthyretin-like domain under physiological conditions

scientific article published on 7 October 2014

Amyloid properties of the leader peptide of variant B cystatin C: implications for Alzheimer and macular degeneration

scientific journal article

Amyloid-like properties of bacterial inclusion bodies.

scientific article

Amyloid-like protein inclusions in tobacco transgenic plants

scientific article

Amyloidogenic regions and interaction surfaces overlap in globular proteins related to conformational diseases

scientific article

Amyloids in bacterial inclusion bodies

scientific article published on 03 August 2009

Amyloids or prions? That is the question

scientific article published on January 2015

Association between foldability and aggregation propensity in small disulfide-rich proteins

scientific article published on 5 May 2014

Bacterial inclusion bodies of Alzheimer's disease β-amyloid peptides can be employed to study native-like aggregation intermediate states

scientific article published on 10 January 2011

Benzbromarone, Quercetin, and Folic Acid Inhibit Amylin Aggregation

scientific article

Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity

article

Bimolecular fluorescence complementation: illuminating cellular protein interactions.

scientific article published on October 2011

Biological role of bacterial inclusion bodies: a model for amyloid aggregation

scientific article published on 31 May 2011

C-mannosylation supports folding and enhances stability of thrombospondin repeats

scientific article published on 23 December 2019

Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation

scientific article published on 24 March 2017

Characterization of Amyloid Cores in Prion Domains

scientific article published on 30 September 2016

Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases

scientific article published on 27 March 2019

Characterization of Soft Amyloid Cores in Human Prion-Like Proteins

scientific article published on 21 September 2017

Characterization of amyloid-like properties in bacterial intracellular aggregates

scientific article

Characterization of the amyloid bacterial inclusion bodies of the HET-s fungal prion

scientific article published on 28 October 2009

Characterizing the Tick Carboxypeptidase Inhibitor

scientific article published in Journal of Biological Chemistry

Coiled-coil inspired functional inclusion bodies

scientific article published on 01 June 2020

Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility

scientific article published on 06 August 2018

Computational Assessment of Bacterial Protein Structures Indicates a Selection Against Aggregation

scientific article published on 08 August 2019

Computational analysis of candidate prion-like proteins in bacteria and their role

scientific article published on 15 October 2015

Computational re-design of protein structures to improve solubility

scientific article published on 08 July 2019

Conformational strain in the hydrophobic core and its implications for protein folding and design

scientific article

Contribution of disulfide bonds to stability, folding, and amyloid fibril formation: the PI3-SH3 domain case

scientific article published on 15 September 2011

Copper(II) and the pathological H50Q α-synuclein mutant: Environment meets genetics

scientific article published on 6 February 2017

Correction: Structure-Based Analysis of A19D, a Variant of Transthyretin Involved in Familial Amyloid Cardiomyopathy.

scientific article published on 31 December 2013

Cross-β-Sheet Supersecondary Structure in Amyloid Folds: Techniques for Detection and Characterization ⬇️

scientific article published on 01 January 2013

Crystal structure of an oligomer of proteolytic zymogens: detailed conformational analysis of the bovine ternary complex and implications for their activation 1 1Edited by I. A. Wilson

article

Crystallization and preliminary X-ray analysis of the ternary complex of procarboxypeptidase A from bovine pancreas

scientific article published on 01 July 1995

Curing bacterial infections with protein aggregates.

scientific article published on 29 December 2015

Cutting at the right place. The importance of selective limited proteolysis in the activation of proproteinase E

article

Data on correlation between Aβ42 structural aggregation propensity and toxicity in bacteria

scientific article

Deciphering the Structural Basis That Guides the Oxidative Folding of Leech-derived Tryptase Inhibitor

scientific article

Deciphering the role of the thermodynamic and kinetic stabilities of SH3 domains on their aggregation inside bacteria

scientific article

Design and NMR conformational study of a beta-sheet peptide based on Betanova and WW domains.

scientific article published on 8 September 2006

Design, selection, and characterization of thioflavin-based intercalation compounds with metal chelating properties for application in Alzheimer's disease

scientific article published in February 2009

Designing out disulfide bonds of leech carboxypeptidase inhibitor: implications for its folding, stability and function

scientific article

Designing proteins from the inside out.

scientific article published on July 2004

Detailed molecular comparison between the inhibition mode of A/B-type carboxypeptidases in the zymogen state and by the endogenous inhibitor latexin

scientific article

Detecting and interfering protein interactions: towards the control of biochemical pathways.

scientific article published on January 2009

Detection of transient protein-protein interactions by bimolecular fluorescence complementation: the Abl-SH3 case.

scientific article

Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid)

scientific article

DisProt 7.0: a major update of the database of disordered proteins

scientific article published on 13 December 2016

DisProt 7.0: a major update of the database of disordered proteins.

scientific article

Discovering Putative Prion-Like Proteins in : A Computational and Experimental Analysis

scientific article published on 07 August 2018

Discovering putative prion sequences in complete proteomes using probabilistic representations of Q/N-rich domains

scientific article

Discovery of novel inhibitors of amyloid β-peptide 1-42 aggregation.

scientific article published in 2012

Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation

scientific article published on 31 July 2021

DispHred: A Server to Predict pH-Dependent Order-Disorder Transitions in Intrinsically Disordered Proteins

scientific article published on 13 August 2020

Dissecting the contribution of Staphylococcus aureus α-phenol-soluble modulins to biofilm amyloid structure

scientific article published on 06 October 2016

Disulfide driven folding for a conditionally disordered protein.

scientific article

Dual Binding Mode of Metallacarborane Produces a Robust Shield on Proteins

scientific article published on 09 September 2019

Dynamics study on single and multiple β-sheets

article

Editorial: Protein Solubility and Aggregation in Bacteria

scientific article published on 29 July 2016

Effect of the surface charge of artificial model membranes on the aggregation of amyloid β-peptide

scientific article published on 20 April 2012

Energy barriers for HET-s prion forming domain amyloid formation

scientific article

Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity.

scientific article published on 05 October 2016

Evaluation of the Impact of Protein Aggregation on Cellular Oxidative Stress in Yeast

scientific article published on 23 June 2018

Evolutionary selection for protein aggregation

scientific article published on October 2012

Fluorescent dye ProteoStat to detect and discriminate intracellular amyloid-like aggregates in Escherichia coli

scientific article published on 8 September 2014

Folding of small disulfide-rich proteins: clarifying the puzzle.

scientific article

Folding specificity induced by loop stiffness

scientific article

Formation of Cross-Beta Supersecondary Structure by Soft-Amyloid Cores: Strategies for Their Prediction and Characterization

scientific article published on 01 January 2019

Global Protein Stabilization Does Not Suffice to Prevent Amyloid Fibril Formation

scientific article published on 16 July 2018

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

High-Throughput Screening Methodology to Identify Alpha-Synuclein Aggregation Inhibitors

scientific article

Histone H1 Favors Folding and Parallel Fibrillar Aggregation of the 1–42 Amyloid-β Peptide

scientific article published on 08 June 2015

Human kallikrein 6 activity is regulated via an autoproteolytic mechanism of activation/inactivation.

scientific article published in June 2004

Human stefin B role in cell's response to misfolded proteins and autophagy

scientific article (publication date: 2014)

Identification of a new variant of TTR involved in familial amyloid cardiomyopathy (FAC) in Brazil: from the patient to the protein.

scientific article published on 2 November 2015

In vivo amyloid aggregation kinetics tracked by time-lapse confocal microscopy in real-time

scientific article published on 18 November 2015

Inclusion bodies: Specificity in their aggregation process and amyloid-like structure

Inducing α-synuclein compaction: a new strategy for inhibiting α-synuclein aggregation?

scientific article published on 01 November 2019

Influence of Cytoplasmatic Folding on Mitochondrial Import.

scientific article

Insights into the origin of the tendency of the PI3-SH3 domain to form amyloid fibrils

scientific article

Intradomain Confinement of Disulfides in the Folding of Two Consecutive Modules of the LDL Receptor

scientific article published on 13 July 2015

Kinetic and thermodynamic stability of bacterial intracellular aggregates

scientific article published on 7 October 2008

Linking amyloid protein aggregation and yeast survival

scientific article

Mammalian prion amyloid formation in bacteria.

scientific article

Mammalian prion protein (PrP) forms conformationally different amyloid intracellular aggregates in bacteria.

scientific article published on 4 November 2015

Mapping the pro-region of carboxypeptidase B by protein engineering. Cloning, overexpression, and mutagenesis of the porcine proenzyme

scientific article published in July 1999

Minimalist Prion-Inspired Polar Self-Assembling Peptides

scientific article published on 04 June 2018

Modeling amyloids in bacteria.

scientific article

Modulation of Abeta42 fibrillogenesis by glycosaminoglycan structure

scientific article published on 28 June 2010

Molecular and Clinical Aspects of Protein Aggregation Assays in Neurodegenerative Diseases.

scientific article published on 10 February 2018

Molecular dynamics study of amyloid formation of two Abl-SH3 domain peptides

scientific article

Monitoring the interference of protein-protein interactions in vivo by bimolecular fluorescence complementation: the DnaK case

scientific article published in September 2008

Multiple β-sheet molecular dynamics of amyloid formation from two ABl-SH3 domain peptides

scientific article published in January 2012

N-Terminal Protein Tails Act as Aggregation Protective Entropic Bristles: The SUMO Case

scientific article published on 06 March 2014

NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor

scientific article published in August 2005

Native structure protects SUMO proteins from aggregation into amyloid fibrils

scientific article published on May 25, 2012

Overexpression of Human Procarboxypeptidase A2 inPichia pastorisand Detailed Characterization of Its Activation Pathway

scientific article published in Journal of Biological Chemistry

Oxidative Protein Folding: From the Test Tube to In Vivo Insights

scientific article published on 01 January 2008

Oxidative folding in the mitochondrial intermembrane space in human health and disease

scientific article published on 30 January 2013

Oxidative folding of leech-derived tryptase inhibitor via native disulfide-bonded intermediates

scientific article published in January 2008

Pancreatic procarboxypeptidases: oligomeric structures and activation processes revisited.

scientific article published on March 1997

Perfecting prediction of mutational impact on the aggregation propensity of the ALS-associated hnRNPA2 prion-like protein

scientific article published on 25 May 2017

Plasticity in the Oxidative Folding Pathway of the High Affinity Nerita Versicolor Carboxypeptidase Inhibitor (NvCI).

scientific article published on 14 July 2017

Possible roles of amyloids in malaria pathophysiology

scientific article published on September 2015

Prediction of "hot spots" of aggregation in disease-linked polypeptides

scientific article

Prediction of the aggregation propensity of proteins from the primary sequence: aggregation properties of proteomes.

scientific article published on 29 April 2011

Prion and non-prion amyloids of the HET-s prion forming domain.

scientific article published on 22 May 2007

Prion domains as a driving force for the assembly of functional nanomaterials

scientific article published on 01 December 2020

Prion soft amyloid core driven self-assembly of globular proteins into bioactive nanofibrils

scientific article published on 25 June 2019

Prion-based nanomaterials and their emerging applications

scientific article published on 02 October 2018

Prion-like proteins and their computational identification in proteomes.

scientific article published on 8 March 2017

PrionScan: an online database of predicted prion domains in complete proteomes.

scientific article published on 5 February 2014

PrionW: a server to identify proteins containing glutamine/asparagine rich prion-like domains and their amyloid cores

scientific article published on 14 May 2015

Procarboxypeptidase in rat pancreas. Overall characterization and comparison of the activation processes

scientific journal article

Protease inhibitors as models for the study of oxidative folding.

scientific article published on 12 October 2010

Protein Environment: A Crucial Triggering Factor in Josephin Domain Aggregation: The Role of 2,2,2-Trifluoroethanol

scientific article published on 24 July 2018

Protein aggregation into insoluble deposits protects from oxidative stress

scientific article published on 4 April 2017

Protein aggregation profile of the bacterial cytosol

scientific article

Protein aggregation profile of the human kinome

scientific article published on 20 November 2012

Protein aggregation propensity is a crucial determinant of intracellular inclusion formation and quality control degradation

scientific article published on 12 July 2013

Protein aggregation: mechanisms and functional consequences.

scientific article published on 17 June 2012

Protein complementation assays: approaches for the in vivo analysis of protein interactions

scientific article published on 06 March 2009

Protein folding and aggregation in bacteria

scientific article published on April 2010

Protein misfolding diseases.

scientific article

Protein oxidative folding in the intermembrane mitochondrial space: more than protein trafficking.

scientific article published on May 2012

Protein quality in bacterial inclusion bodies.

scientific article

Proteome response at the edge of protein aggregation

scientific article published on February 2015

Reply to Comment on "N-terminal Protein Tail Acts as Aggregation Protective Entropic Bristles: The SUMO Case"

scientific article published on 24 July 2020

Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity.

scientific article published on 23 February 2016

SGnn: A Web Server for the Prediction of Prion-Like Domains Recruitment to Stress Granules Upon Heat Stress

scientific article published on 18 August 2021

SOM0226, a repositioned compound for the treatment of TTR amyloidosis

scientific article published on 2 November 2015

Scrambled isomers as key intermediates in the oxidative folding of ligand binding module 5 of the low density lipoprotein receptor

scientific article

Screening Protein Aggregation in Cells Using Fluorescent Labels Coupled to Flow Cytometry

scientific article published on 01 January 2019

Screening for amyloid aggregation: in-silico, in-vitro and in-vivo detection

scientific article published on January 2014

Selection against toxic aggregation-prone protein sequences in bacteria

scientific article

Self-assembly of human latexin into amyloid-like oligomers.

scientific article

Sequence determinants of protein aggregation: tools to increase protein solubility

scientific article

Short amino acid stretches can mediate amyloid formation in globular proteins: the Src homology 3 (SH3) case

scientific article

Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons

article published in the Proceedings of the National Academy of Sciences of the United States of America

Soluble Assemblies in the Fibrillation Pathway of Prion-Inspired Artificial Functional Amyloids are Highly Cytotoxic

scientific article published on 10 April 2020

SolupHred: A Server to Predict the pH-dependent Aggregation of Intrinsically Disordered Proteins

scientific article published on 24 October 2020

Special Issue: "Inflammation, Oxidative Stress and Protein Aggregation; Any Links?"

scientific article published on 11 November 2020

Specific Hsp100 Chaperones Determine the Fate of the First Enzyme of the Plastidial Isoprenoid Pathway for Either Refolding or Degradation by the Stromal Clp Protease in Arabidopsis

scientific article

Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals.

scientific article

Structure and dynamics of the potato carboxypeptidase inhibitor by 1H and 15N NMR

scientific article (publication date: 15 February 2003)

Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin

scientific article

Structure-based analysis of A19D, a variant of transthyretin involved in familial amyloid cardiomyopathy

scientific article

Studies on bacterial inclusion bodies

scientific article published on August 2008

Study and selection of in vivo protein interactions by coupling bimolecular fluorescence complementation and flow cytometry.

scientific article

Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond

scientific article published in September 2005

Sulfated polysaccharides promote the assembly of amyloid beta(1-42) peptide into stable fibrils of reduced cytotoxicity

scientific article published on 25 September 2008

Temperature Dependence of the Aggregation Kinetics of Sup35 and Ure2p Yeast Prions

The Disordered C-Terminus of Yeast Hsf1 Contains a Cryptic Low-Complexity Amyloidogenic Region.

scientific article published on 6 May 2018

The N-terminal helix controls the transition between the soluble and amyloid states of an FF domain

scientific article

The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways

scientific article

The Rho Termination Factor of Clostridium botulinum Contains a Prion-Like Domain with a Highly Amyloidogenic Core.

scientific article published on January 2015

The Transcription Terminator Rho: A First Bacterial Prion.

scientific article published on 6 April 2017

The aggregation properties of Escherichia coli proteins associated with their cellular abundance

scientific article published on 29 April 2011

The biofilm-associated surface protein Esp of Enterococcus faecalis forms amyloid-like fibers

scientific article published on 27 March 2020

The chaperone DnaK controls the fractioning of functional protein between soluble and insoluble cell fractions in inclusion body-forming cells.

scientific article published on 07 August 2006

The effect of amyloidogenic peptides on bacterial aging correlates with their intrinsic aggregation propensity

scientific article published on 19 December 2011

The effects of the novel A53E alpha-synuclein mutation on its oligomerization and aggregation.

scientific article published on 9 December 2016

The fitness cost and benefit of phase-separated protein deposits

scientific article published on 08 April 2019

The importance of a gatekeeper residue on the aggregation of transthyretin: implications for transthyretin-related amyloidoses

scientific article published on August 2014

The in vivo and in vitro aggregation properties of globular proteins correlate with their conformational stability: the SH3 case

scientific article

The mitochondrial intermembrane space oxireductase Mia40 funnels the oxidative folding pathway of the cytochrome c oxidase assembly protein Cox19.

scientific article published on 25 February 2014

The prion-like RNA-processing protein HNRPDL forms inherently toxic amyloid-like inclusion bodies in bacteria

scientific article published on 11 July 2015

The role of protein sequence and amino acid composition in amyloid formation: scrambling and backward reading of IAPP amyloid fibrils

scientific article published on 29 September 2010

The small GTPase Rab11 co-localizes with α-synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity

scientific article

Thioflavin-S staining coupled to flow cytometry. A screening tool to detect in vivo protein aggregation ⬇️

scientific article published on August 7, 2012

Thioflavin-S staining of bacterial inclusion bodies for the fast, simple, and inexpensive screening of amyloid aggregation inhibitors

scientific article

Thioflavin-T excimer formation upon interaction with amyloid fibers

scientific article published in June 2013

Trifluoroethanol modulates amyloid formation by the all α-helical URN1 FF domain

scientific article published on 30 August 2013

Understanding and predicting protein misfolding and aggregation: Insights from proteomics

scientific article

Using bacterial inclusion bodies to screen for amyloid aggregation inhibitors

scientific article published on 3 May 2012

What makes a protein sequence a prion?

scientific article published on 8 January 2015

Yeast prions form infectious amyloid inclusion bodies in bacteria

scientific article published on 25 June 2012

Zinc induced folding is essential for TIM15 activity as an mtHsp70 chaperone

scientific article published on 11 October 2012

pH-Dependent Aggregation in Intrinsically Disordered Proteins Is Determined by Charge and Lipophilicity

scientific article published on 08 January 2020

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