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List of works by Stefan Hohmann

A Nonlinear Mixed Effects Approach for Modeling the Cell-To-Cell Variability of Mig1 Dynamics in Yeast

scientific article published on 20 April 2015

A deletion of the PDC1 gene for pyruvate decarboxylase of yeast causes a different phenotype than previously isolated point mutations

article

A framework for mapping, visualisation and automatic model creation of signal-transduction networks

scientific article published on 24 April 2012

A fungicide-responsive kinase as a tool for synthetic cell fate regulation

scientific article

A microfluidic system for studies of stress response in single cells using optical tweezers

A microfluidic system in combination with optical tweezers for analyzing rapid and reversible cytological alterations in single cells upon environmental changes

scientific article published on 4 October 2006

A novel chloroplast localized Rab GTPase protein CPRabA5e is involved in stress, development, thylakoid biogenesis and vesicle transport in Arabidopsis

scientific article

A region in the yeast genome which favours multiple integration of DNA via homologous recombination

scientific article published on 01 January 1987

A regulatory domain in the C-terminal extension of the yeast glycerol channel Fps1p

scientific article published on 28 January 2004

A short regulatory domain restricts glycerol transport through yeast Fps1p.

scientific article

Accumulation and release of the osmolyte glycerol is independent of the putative MIP channel Spac977.17p in Schizosaccharomyces pombe

scientific article published in February 2004

An integrated view on a eukaryotic osmoregulation system

scientific article published on 08 February 2015

Anaerobicity prepares Saccharomyces cerevisiae cells for faster adaptation to osmotic shock

scientific article

Analysis of the pore of the unusual major intrinsic protein channel, yeast Fps1p.

scientific article published on 09 July 2001

Applying Microfluidic Systems to Study Effects of Glucose at Single-Cell Level

scientific article published in January 2018

Aquaporin expression correlates with freeze tolerance in baker's yeast, and overexpression improves freeze tolerance in industrial strains

scientific article

Aquaporins in yeasts and filamentous fungi

scientific article

AtPTR3, a wound-induced peptide transporter needed for defence against virulent bacterial pathogens in Arabidopsis

scientific article published on 02 December 2006

Automated ensemble modeling with modelMaGe: analyzing feedback mechanisms in the Sho1 branch of the HOG pathway

scientific article

Autoregulation may control the expression of yeast pyruvate decarboxylase structural genes PDC1 and PDC5.

scientific article

Autoregulation of yeast pyruvate decarboxylase gene expression requires the enzyme but not its catalytic activity

scientific article

Biophysical properties of Saccharomyces cerevisiae and their relationship with HOG pathway activation

scientific article

Bridging the gaps in systems biology

scientific article published on 13 April 2014

Case study in systematic modelling: thiamine uptake in the yeast Saccharomyces cerevisiae

scientific article

Chapter 8 Integrative analysis of yeast osmoregulation

Chapter 8 Microbial water channels and glycerol facilitators

Chapter 9 Future directions of aquaporin research

Characterisation of PDC2, a gene necessary for high level expression of pyruvate decarboxylase structural genes in Saccharomyces cerevisiae

scientific article

Characteristics of Fps1-dependent and -independent glycerol transport in Saccharomyces cerevisiae.

scientific article published in December 1997

Characterization of PDC6, a third structural gene for pyruvate decarboxylase in Saccharomyces cerevisiae ⬇️

scientific article published on December 1, 1991

Characterization of the osmotic-stress response in Saccharomyces cerevisiae: osmotic stress and glucose repression regulate glycerol-3-phosphate dehydrogenase independently

scientific article published in January 1994

Cloning and expression on a multicopy vector of five invertase genes of Saccharomyces cerevisiae

scientific article

Combination of two activating mutations in one HOG1 gene forms hyperactive enzymes that induce growth arrest

scientific article

Comparative analysis of HOG pathway proteins to generate hypotheses for functional analysis

scientific article published on 9 February 2006

Comparative genomics of the HOG-signalling system in fungi

scientific article published on 9 February 2006

Comparison of the nucleotide sequences of a yeast gene family

article

Comparison of the nucleotide sequences of a yeast gene family

scientific article published on 01 November 1989

Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex.

scientific article

Conditional osmotic stress in yeast: a system to study transport through aquaglyceroporins and osmostress signaling

scientific article published on 17 December 2004

Control of glucose influx into glycolysis and pleiotropic effects studied in different isogenic sets of Saccharomyces cerevisiae mutants in trehalose biosynthesis

scientific article published on 01 January 1995

Control of high osmolarity signalling in the yeast Saccharomyces cerevisiae

scientific article published on December 2009

Crystal Structure of a Yeast Aquaporin at 1.15 Å Reveals a Novel Gating Mechanism

scientific article

Design, synthesis, and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signaling in yeast

scientific article

Different signalling pathways contribute to the control of GPD1 gene expression by osmotic stress in Saccharomyces cerevisiae

scientific article published on March 1999

Differential requirement of the yeast sugar kinases for sugar sensing in establishing the catabolite-repressed state.

scientific article

Differential role of HAMP-like linkers in regulating the functionality of the group III histidine kinase DhNik1p

scientific article

Disruption of the Kluyveromyces lactis GGS1 gene causes inability to grow on glucose and fructose and is suppressed by mutations that reduce sugar uptake

scientific article

Distributed biological computation with multicellular engineered networks

scientific article

Editor's comment on "CRISPR/Cas9-mediated gene editing in human zygotes using Cas9 protein".

scientific article published in March 2017

Efficient construction of homozygous diploid strains identifies genes required for the hyper-filamentous phenotype in Saccharomyces cerevisiae

scientific article

Employing protein size in the functional analysis of orthologous proteins, as illustrated with the yeast HOG pathway

Engineering of a novel Saccharomyces cerevisiae wine strain with a respiratory phenotype at high external glucose concentrations.

scientific article published on October 2005

Erratum: Corrigendum: Integrative model of the response of yeast to osmotic shock

scholarly article published in Nature Biotechnology

Existence of a tightly regulated water channel in Saccharomyces cerevisiae

scientific article published in 2001

Expression of concern: Sequences enhancing cassava mosaic disease symptoms occur in the cassava genome and are associated with South African cassava mosaic virus infection by A. T. Maredza, F. Allie, G. Plata, M. E. C. Rey.

scientific article published on 27 April 2016

Expression of heterologous aquaporins for functional analysis in Saccharomyces cerevisiae

scientific article published on 18 August 2006

Expression of the yeast aquaporin Aqy2 affects cell surface properties under the control of osmoregulatory and morphogenic signalling pathways.

scientific article

Fps1p controls the accumulation and release of the compatible solute glycerol in yeast osmoregulation

scientific article published on 01 February 1999

Fungal fludioxonil sensitivity is diminished by a constitutively active form of the group III histidine kinase

scientific article

GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolarity glycerol response pathway

scientific article

Genome-wide expression profile of the mnn2Δ mutant of Saccharomyces cerevisiae

scientific article published on 19 April 2006

Gis4, a new component of the ion homeostasis system in the yeast Saccharomyces cerevisiae.

scientific article

Glucose de-repression by yeast AMP-activated protein kinase SNF1 is controlled via at least two independent steps

scientific article published on 4 March 2014

Gothenburg special issue: Molecules of Life

scientific article published on 09 May 2010

Hog1-mediated Metabolic Adjustments Following Hyperosmotic Shock in the Yeast Saccharomyces cerevisiae

How quantitative measures unravel design principles in multi-stage phosphorylation cascades

article by Simone Frey et al published September 2008 in Journal of Theoretical Biology

Identification of residues controlling transport through the yeast aquaglyceroporin Fps1 using a genetic screen.

scientific article published in February 2004

Implications of FPS1 deletion and membrane ergosterol content for glycerol efflux from Saccharomyces cerevisiae.

scientific article published in December 2001

Initiation of the transcriptional response to hyperosmotic shock correlates with the potential for volume recovery

scientific article published on 5 July 2013

Integrative model of the response of yeast to osmotic shock

scientific article published on 17 July 2005

Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and apoptosis

scientific article published on 27 December 2007

Isolation and characterization of the TIM10 homologue from the yeast Pichia sorbitophila: a putative component of the mitochondrial protein import system

scientific article published in May 2000

Microbial MIP channels.

scientific article

Mig1 localization exhibits biphasic behavior which is controlled by both metabolic and regulatory roles of the sugar kinases

scientific article published on 19 September 2020

Molecular analysis of the structural gene for yeast transaldolase

scientific article

Molecular and functional study of AQY1 from Saccharomyces cerevisiae: role of the C-terminal domain

scientific article

Molecular communication: crosstalk between the Snf1 and other signaling pathways

scientific article published on 19 May 2015

Network reconstruction and validation of the Snf1/AMPK pathway in baker's yeast based on a comprehensive literature review

scientific article

Nobel Yeast Research

scientific article

Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast

scientific article published on 01 January 1990

Novel alleles of yeast hexokinase PII with distinct effects on catalytic activity and catabolite repression of SUC2

scientific article published on 01 March 1999

One hundred years of Molecular Genetics and Genomics: 100 years of extra-nuclear inheritance

scientific article published in March 2010

Osmostress-induced cell volume loss delays yeast Hog1 signaling by limiting diffusion processes and by Hog1-specific effects

scientific article (publication date: 2013)

Osmotic adaptation in yeast--control of the yeast osmolyte system

scientific article

Osmotic stress signaling and osmoadaptation in yeasts

scientific article

Osmotic stress-induced gene expression in Saccharomyces cerevisiae requires Msn1p and the novel nuclear factor Hot1p

scientific article

PDC6, a weakly expressed pyruvate decarboxylase gene from yeast, is activated when fused spontaneously under the control of the PDC1 promoter ⬇️

scientific article published on November 1, 1991

Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae

scientific article

Pheromone-induced morphogenesis improves osmoadaptation capacity by activating the HOG MAPK pathway

scientific article published on 23 April 2013

Polymorphism of Saccharomyces cerevisiae aquaporins

scientific article published in July 2000

Preface

scientific article published on 21 July 2011

Production, characterization and crystallization of the Plasmodium falciparum aquaporin

scientific article

Quantification of cell volume changes upon hyperosmotic stress in Saccharomyces cerevisiae

scientific article published on 19 October 2011

Quantitative analysis of glycerol accumulation, glycolysis and growth under hyper osmotic stress

scientific article

Regulation der Genexpression— Molekulare Mechanismen bei Eukaryoten

Regulation of genes encoding subunits of the trehalose synthase complex in

article

Regulation of genes encoding subunits of the trehalose synthase complex in Saccharomyces cerevisiae: novel variations of STRE-mediated transcription control?

scientific article published on 01 September 1996

Rewiring yeast osmostress signalling through the MAPK network reveals essential and non-essential roles of Hog1 in osmoadaptation

scientific article published on 15 April 2014

Robustness and fragility in the yeast high osmolarity glycerol (HOG) signal-transduction pathway

scientific article published on 16 June 2009

Role of Glu51 for Cofactor Binding and Catalytic Activity in Pyruvate Decarboxylase from Yeast Studied by Site-Directed Mutagenesis†

scientific article published on 01 February 1997

Role of cysteines in the activation and inactivation of brewers' yeast pyruvate decarboxylase investigated with a PDC1-PDC6 fusion protein

scientific article published on 01 March 1993

Role of hexose transport in control of glycolytic flux in Saccharomyces cerevisiae

scientific article

Role of trehalose in survival of Saccharomyces cerevisiae under osmotic stress ⬇️

scientific article published on March 1, 1998

Roles of Sugar Alcohols in Osmotic Stress Adaptation. Replacement of Glycerol by Mannitol and Sorbitol in Yeast

scientific article published on 01 September 1999

Saccharomyces cerevisiae Spore Germination

Ser3p (Yer081wp) and Ser33p (Yil074cp) are phosphoglycerate dehydrogenases in Saccharomyces cerevisiae

scientific article

Short cut to 1,2,3-triazole-based p38 MAP kinase inhibitorsvia [3+2]-cycloaddition chemistry

Shutting the MAP Off - and On Again?

Single-cell study links metabolism with nutrient signaling and reveals sources of variability

scientific article

Stimulation of the yeast high osmolarity glycerol (HOG) pathway: evidence for a signal generated by a change in turgor rather than by water stress

scientific article published on 01 April 2000

Strategy for deletion of complete open reading frames in Saccharomyces cerevisiae

scientific article published in March 1995

Structural analysis of the 5' regions of yeast SUC genes revealed analogous palindromes in SUC, MAL and GAL.

scientific article published in March 1988

Substrate activation of brewers' yeast pyruvate decarboxylase is abolished by mutation of cysteine 221 to serine.

scientific article published on May 1994

Switching the mode of metabolism in the yeast Saccharomyces cerevisiae

scientific article

Synthetic biology: lessons from engineering yeast MAPK signalling pathways

scientific article

Systems Biology: Nobel Symposium 146.

scientific article

Systems Level Analysis of the Yeast Osmo-Stat

scientific article published on 12 August 2016

The Ashbya gossypii EF-1α promoter of the ubiquitously used MX cassettes is toxic to Saccharomyces cerevisiae

scientific article published on 22 October 2011

The FPS1 gene product functions as a glycerol facilitator in the yeast Saccharomyces cerevisiae

scientific article

The Pep4p vacuolar proteinase contributes to the turnover of oxidized proteins but PEP4 overexpression is not sufficient to increase chronological lifespan in Saccharomyces cerevisiae

scientific article published on 01 December 2006

The Saccharomyces cerevisiae Sko1p transcription factor mediates HOG pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage

scientific article

The Saccharomyces cerevisiae aquaporin Aqy1 is involved in sporulation

scientific article

The Yeast Systems Biology Network: mating communities

scientific article

The byp1-3 allele of the Saccharomyces cerevisiae GGS1/TPS1 gene and its multi-copy suppressor tRNA(GLN) (CAG): Ggs1/Tps1 protein levels restraining growth on fermentable sugars and trehalose accumulation

scientific article published in October 1994

The cell division cycle gene CDC60 encodes cytosolic leucyl-tRNA synthetase in Saccharomyces cerevisiae

scientific article published on October 12, 1992

The genome of the xerotolerant mold Wallemia sebi reveals adaptations to osmotic stress and suggests cryptic sexual reproduction

scientific article

The growth and signalling defects of the ggs1 (fdp1/byp1) deletion mutant on glucose are suppressed by a deletion of the gene encoding hexokinase PII

article

The mammalian AMP-activated protein kinase complex mediates glucose regulation of gene expression in the yeast Saccharomyces cerevisiae

article

The mitogen-activated protein kinase Slt2 modulates arsenite transport through the aquaglyceroporin Fps1.

scientific article

The naturally occurring silent invertase structural gene suc2� contains an amber stop codon that is occasionally read through

article

The pathway by which the yeast protein kinase Snf1p controls acquisition of sodium tolerance is different from that mediating glucose regulation

scientific article published in September 2008

The transcriptional response of Saccharomyces cerevisiae to osmotic shock. Hot1p and Msn2p/Msn4p are required for the induction of subsets of high osmolarity glycerol pathway-dependent genes.

scientific article

The two isoenzymes for yeast NAD+-dependent glycerol 3-phosphate dehydrogenase encoded by GPD1 and GPD2 have distinct roles in osmoadaptation and redox regulation

scientific article published in May 1997

The yeast Mig1 transcriptional repressor is dephosphorylated by glucose-dependent and -independent mechanisms.

scientific article published in August 2017

The yeast glycerol 3-phosphatases Gpp1p and Gpp2p are required for glycerol biosynthesis and differentially involved in the cellular responses to osmotic, anaerobic, and oxidative stress

scientific article

The yeast osmostress response is carbon source dependent

scientific article published on 20 April 2017

Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation

scientific article published on June 1998

Thiamine repression and pyruvate decarboxylase autoregulation independently control the expression of the Saccharomyces cerevisiae PDC5 gene

article

Time course gene expression profiling of yeast spore germination reveals a network of transcription factors orchestrating the global response

scientific article

Transcription factor clusters regulate genes in eukaryotic cells.

scientific article published on 25 August 2017

Transcriptional responses to glucose at different glycolytic rates in Saccharomyces cerevisiae

scientific article published in December 2004

Transposon mutagenesis reveals novel loci affecting tolerance to salt stress and growth at low temperature

scientific article published on 01 August 2001

Trehalose accumulation in mutants of Saccharomyces cerevisiae deleted in the UDPG-dependent trehalose synthase-phosphatase complex

scientific article published on 01 April 1997

Yeast AMP-activated protein kinase monitors glucose concentration changes and absolute glucose levels

scientific article published on 13 March 2014

Yeast aquaglyceroporins use the transmembrane core to restrict glycerol transport.

scientific article

Yeast osmoregulation

scientific article published on January 2007

Yeast reveals unexpected roles and regulatory features of aquaporins and aquaglyceroporins

scientific article published on 26 September 2013

Yeast systems biology to unravel the network of life

scientific article

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