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List of works by Marcel Schilling

Cellular ERK phospho-form profiles with conserved preference for a switch-like pattern.

scientific article

Computational processing and error reduction strategies for standardized quantitative data in biological networks

scientific article

Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation

scientific article published on 2 February 2016

Covering a broad dynamic range: information processing at the erythropoietin receptor

scientific article

Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems

scientific article

Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction

scientific article published on 01 July 2020

Disentangling the Complexity of HGF Signaling by Combining Qualitative and Quantitative Modeling

scientific article published on 23 April 2015

Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.

scientific article

Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets

scientific article published on 2 December 2010

Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response.

scientific article published on 22 June 2018

Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU

scientific article (publication date: 16 January 2004)

Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells

scientific article

Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses

scientific article published on 01 October 2020

Identification of isoform-specific dynamics in phosphorylation-dependent STAT5 dimerization by quantitative mass spectrometry and mathematical modeling

scientific article

In silico labeling reveals the time-dependent label half-life and transit-time in dynamical systems.

scientific article

Lessons learned from quantitative dynamical modeling in systems biology

scientific article

MSPypeline: a python package for streamlined data analysis of mass spectrometry-based proteomics

scientific article published on 13 January 2022

Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib.

scientific article published on 9 October 2017

Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds.

scientific article published on 11 June 2018

Predictive mathematical models of cancer signalling pathways

scientific article published on February 2012

Protein abundance of AKT and ERK pathway components governs cell type-specific regulation of proliferation

scientific article published on 24 January 2017

Quantitative data generation for systems biology: the impact of randomisation, calibrators and normalisers.

scientific article

Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression

scientific article published on 12 December 2017

Short-term information processing, long-term responses: Insights by mathematical modeling of signal transduction. Early activation dynamics of key signaling mediators can be predictive for cell fate decisions

scientific article published on 23 April 2012

Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood

scientific article

T160‐phosphorylated CDK2 defines threshold for HGF dependent proliferation in primary hepatocytes

scientific article

Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions

scientific article

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