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List of works by Lyle McKinnon

Biological factors that may contribute to regional and racial disparities in HIV prevalence

scientific article

Blunted IL17/IL22 and pro-inflammatory cytokine responses in the genital tract and blood of HIV-exposed, seronegative female sex workers in Kenya

scientific article

CD26/dipeptidyl peptidase IV (CD26/DPPIV) is highly expressed in peripheral blood of HIV-1 exposed uninfected female sex workers

scientific article

Characterization of a human cervical CD4+ T cell subset coexpressing multiple markers of HIV susceptibility

scientific article

Clade-specific evolution mediated by HLA-B*57/5801 in human immunodeficiency virus type 1 clade A1 p24.

scientific article published on 16 September 2009

Correction: Enumeration of Sex Workers in the Central Business District of Nairobi, Kenya.

scientific article published on 20 November 2013

Correction: Non-Cationic Proteins Are Associated with HIV Neutralizing Activity in Genital Secretions of Female Sex Workers

scientific article published on 21 July 2015

Cross-Clade CD8+ T-Cell Responses With a Preference for the Predominant Circulating Clade

article

Defining genital tract cytokine signatures of sexually transmitted infections and bacterial vaginosis in women at high risk of HIV infection: a cross-sectional study

scientific article published on 08 August 2014

Descriptive Epidemiology of Factors Associated with HIV Infections Among Men and Transgender Women Who Have Sex with Men in South India

scientific article published on 08 April 2016

Does antiretroviral therapy initiation increase sexual risk taking in Kenyan female sex workers? A retrospective case-control study

scientific article published in April 2012

Early HIV-1 infection is associated with reduced frequencies of cervical Th17 cells

scientific article published on January 2015

Effect of baseline HIV disease parameters on CD4+ T cell recovery after antiretroviral therapy initiation in Kenyan women

scientific article

Enumeration of sex workers in the central business district of Nairobi, Kenya

scientific article

Epitope cross-reactivity frequently differs between central and effector memory HIV-specific CD8+ T cells

scientific article published in March 2007

Epitope mapping of HIV-specific CD8+ T cell responses by multiple immunological readouts reveals distinct specificities defined by function

scientific article

Epitope mapping of HIV-specific CD8+ T cells in a cohort dominated by clade A1 infection

scientific article

Evaluation of a quantitative real-time PCR assay to measure HIV-specific mucosal CD8+ T cell responses in the cervix

scientific article

Ex vivo HIV entry into blood CD4+ T cells does not predict heterosexual HIV acquisition in women

scientific article published in PLoS ONE

Factors Driving the HIV Epidemic in Southern Africa

scientific article

Genital immunology and HIV susceptibility in young women

scientific article

Genital inflammation undermines the effectiveness of tenofovir gel in preventing HIV acquisition in women

scientific article published on 26 February 2018

Genital-Systemic Chemokine Gradients and the Risk of HIV Acquisition in Women

scientific article published on March 2017

HIV postexposure prophylaxis in an urban population of female sex workers in Nairobi, Kenya

scientific article

HIV-1 RNA dysregulates the natural TLR response to subclinical endotoxemia in Kenyan female sex-workers

scientific article

HIV-1 clade D is associated with increased rates of CD4 decline in a Kenyan cohort

scientific article

HIV-specific CD8+ T-cell proliferation is prospectively associated with delayed disease progression

scientific article

HIV-specific T cells: strategies for fighting a moving target

scientific article

High HIV risk in a cohort of male sex workers from Nairobi, Kenya

scientific article published on 13 December 2013

Honing in on enteric fever

scientific article

Identification of a novel HLA-DQA1 null allele, DQA1*0403N, from an East African woman

scientific article

Identification of preferential CD4+ T-cell targets for HIV infection in the cervix.

scientific article published on 15 April 2015

Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins, and an influx of HIV-susceptible target cells

scientific article published on 24 June 2015

Inflammation and HIV Transmission in Sub-Saharan Africa

scientific article published on June 2015

Integrin α4β7 expression on peripheral blood CD4+ T cells predicts HIV acquisition and disease progression outcomes.

scientific article published in January 2018

Interferon regulatory factor 1 polymorphisms previously associated with reduced HIV susceptibility have no effect on HIV disease progression

scientific article

Interleukin 1-Beta (IL-1β) Production by Innate Cells Following TLR Stimulation Correlates With TB Recurrence in ART-Treated HIV-Infected Patients

scientific article published on 19 September 2016

Live Attenuated Zoster Vaccine Boosts Varicella Zoster Virus (VZV)-Specific Humoral Responses Systemically and at the Cervicovaginal Mucosa of Kenyan VZV-Seropositive Women

article

Lower concentrations of chemotactic cytokines and soluble innate factors in the lower female genital tract associated with the use of injectable hormonal contraceptive

scientific article published on 22 April 2015

Measurements of immune responses for establishing correlates of vaccine protection against HIV

scientific article (publication date: July 2012)

Microbial translocation and microbiome dysbiosis in HIV-associated immune activation

scientific article published on 16 December 2015

Microbiome Composition and Function Drives Wound-Healing Impairment in the Female Genital Tract

scientific article

Mucosal HIV Shedding During ART.

scientific article published on 12 December 2017

Mucosal Th17 cell function is altered during HIV infection and is an independent predictor of systemic immune activation

scientific article published on 26 July 2013

Multiple T-cell epitopes overlap positively-selected residues in the p1 spacer protein of HIV-1 gag.

scientific article published on April 2009

Mx2 expression is associated with reduced susceptibility to HIV infection in highly exposed HIV seronegative Kenyan sex workers

scientific article published on January 2015

Mycobacterium tuberculosis strains induce strain-specific cytokine and chemokine response in pulmonary epithelial cells

scientific article published on 9 October 2017

Non-Cationic Proteins Are Associated with HIV Neutralizing Activity in Genital Secretions of Female Sex Workers

scientific article

Optimizing viable leukocyte sampling from the female genital tract for clinical trials: an international multi-site study

scientific article published on 15 January 2014

P16-15. Epitope mapping of HIV-specific CD8+ T-cells responses by polyfunctional and proliferation responses reveal distinct specificity defined by function

scientific article

P16-27.Optimization of the expansion of antigen-specific CD8+ T-cells for use in a viral suppression assay

Plasma Cytokine Predictors of Tuberculosis Recurrence in Antiretroviral-Treated Human Immunodeficiency Virus-infected Individuals from Durban, South Africa

scientific article published on September 2017

PrEP for key populations in combination HIV prevention in Nairobi: a mathematical modelling study

scientific article published on 20 February 2017

Quality and quantity: mucosal CD4+ T cells and HIV susceptibility

scientific article

Rapid disease progression in HIV-1 subtype C-infected South African women

scientific article

Relationship between female genital tract infections, mucosal interleukin-17 production and local T helper type 17 cells

scientific article published on 24 August 2015

Repeat Use of Post-exposure Prophylaxis for HIV Among Nairobi-Based Female Sex Workers Following Sexual Exposure

scientific article published on 13 May 2015

Risk Factors for HIV Acquisition in a Prospective Nairobi-Based Female Sex Worker Cohort

scientific article published on 20 June 2015

Role of semen in altering the balance between inflammation and tolerance in the female genital tract: does it contribute to HIV risk?

scientific article published on 12 May 2014

Strengthening HIV surveillance in the antiretroviral therapy era: rationale and design of a longitudinal study to monitor HIV prevalence and incidence in the uMgungundlovu District, KwaZulu-Natal, South Africa

scientific article published on 20 November 2015

Substantial intrapatient differences in the breadth and specificity of HIV-specific CD8+ T-cell interferon-gamma and proliferation responses

scientific article published in October 2008

Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy

scientific article

The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.

scientific article

The rise and fall of HIV in high-prevalence countries: a challenge for mathematical modeling.

scientific article

The role of dendritic cells in driving genital tract inflammation and HIV transmission risk: are there opportunities to intervene?

scientific article

Toll-like receptor expression and responsiveness are increased in viraemic HIV-1 infection

scientific article published in March 2008

Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women

scientific article

Vaginal microbiome-hormonal contraceptive interactions associate with the mucosal proteome and HIV acquisition

scientific article published on 23 December 2020

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