List of works - Alfred Antson

11-fold symmetry of the trp RNA-binding attenuation protein (TRAP) from Bacillus subtilis determined by X-ray analysis

scientific article published on 01 November 1994

12-Fold symmetry of the putative portal protein from the Thermus thermophilus bacteriophage G20C determined by X-ray analysis

scientific article published on 17 October 2013

A flexible brace maintains the assembly of a hexameric replicative helicase during DNA unwinding

scientific article published on 8 November 2011

Anti-TRAP protein from Bacillus subtilis: crystallization and internal symmetry

scientific article

Bacillus licheniformis Anti-TRAP can assemble into two types of dodecameric particles with the same symmetry but inverted orientation of trimers

scientific article

Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners

scientific article published on 20 September 2017

Circular assemblies

scientific article

Complexity in regulation of tryptophan biosynthesis in Bacillus subtilis

scientific article

Conformational flexibility and molecular interactions of an archaeal homologue of the Shwachman-Bodian-Diamond syndrome protein

scientific article

Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids

article published in the Proceedings of the National Academy of Sciences of the United States of America

Cryo-EM structure in situ reveals a molecular switch that safeguards virus against genome loss

scientific article published on 14 April 2020

Crystal structure of Bacillus anthracis ThiI, a tRNA-modifying enzyme containing the predicted RNA-binding THUMP domain

scientific article

Crystal structure of Bacillus cereus HlyIIR, a transcriptional regulator of the gene for pore-forming toxin hemolysin II.

scientific article

Crystal structure of Bacillus subtilis anti-TRAP protein, an antagonist of TRAP/RNA interaction

scientific article

Crystal structure of Mil (Mth680): internal duplication and similarity between the Imp4/Brix domain and the anticodon-binding domain of class IIa aminoacyl-tRNA synthetases

scientific article

Crystal structure of tryptophanase

scientific article

Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of human dihydrouridine synthase ⬇️

scientific article published on February 22, 2012

Crystallization and preliminary X-ray diffraction of Trypanosoma cruzi dUTPase

scientific article published on 01 February 1999

Crystallization and preliminary X-ray investigation of holotryptophanases from Escherichia coli and Proteus vulgaris.

scientific article

Crystallographic Snapshots of Tyrosine Phenol-lyase Show That Substrate Strain Plays a Role in C–C Bond Cleavage

scientific article

DNA recognition for virus assembly through multiple sequence-independent interactions with a helix-turn-helix motif.

scientific article published on 15 December 2015

Determination of interspin distances between spin labels attached to insulin: comparison of electron paramagnetic resonance data with the X-ray structure.

scientific article published in December 1997

Dimerization of the human papillomavirus type 16 E2 N terminus results in DNA looping within the upstream regulatory region

scientific article

Diversity and Host Interactions Among Virulent and Temperate Baltic Sea Flavobacterium Phages

scientific article published on 30 January 2020

Expression, crystallization and preliminary X-ray analysis of the E2 transactivation domain from papillomavirus type 16

scientific article published on 01 November 1998

Expression, purification, crystallization and preliminary X-ray studies of the TAN1 orthologue from Methanothermobacter thermautotrophicus

scientific article published on 31 October 2008

From bacterial to human dihydrouridine synthase: automated structure determination

scientific article

Going for RNA repeats

scientific article published on 01 April 2005

How to Change the Oligomeric State of a Circular Protein Assembly: Switch from 11-Subunit to 12-Subunit TRAP Suggests a General Mechanism

scientific article

Human Lin28 Forms a High-Affinity 1:1 Complex with the 106~363 Cluster miRNA miR-363.

scientific article published on September 2016

Insights into the Catalytic Mechanism of Tyrosine Phenol-lyase from X-ray Structures of Quinonoid Intermediates

scientific article

Interaction of the 11-subunit trp RNA-binding attenuation protein (TRAP) with its RNA target

scientific article published on 01 January 1995

Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues

scientific article

Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases

scientific article published on 22 April 2015

Monomeric 14-3-3ζ has a chaperone-like activity and is stabilized by phosphorylated HspB6.

scientific article published on 25 July 2012

Papillomavirus E1 helicase assembly maintains an asymmetric state in the absence of DNA and nucleotide cofactors

scientific article

Porphyrin-Assisted Docking of a Thermophage Portal Protein into Lipid Bilayers: Nanopore Engineering and Characterization.

scientific article published on 9 November 2017

Properties of the monomeric form of human 14-3-3ζ protein and its interaction with tau and HspB6.

scientific article

Quantitative characterization of protein-protein complexes involved in base excision DNA repair

scientific article published on 26 May 2015

RNA protects a nucleoprotein complex against radiation damage

scientific article (publication date: May 2016)

Recombinant portal protein from Staphylococcus epidermidis bacteriophage CNPH82 is a 13-subunit oligomer

scientific article

Regulatory features of the trp operon and the crystal structure of the trp RNA-binding attenuation protein from Bacillus stearothermophilus

scientific article

S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA

scientific article

Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator

scientific article published on 30 December 2016

Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase

Structural basis for DNA recognition and loading into a viral packaging motor

scientific article

Structural basis for DNA strand separation by a hexameric replicative helicase

scientific article

Structural basis for the nuclease activity of a bacteriophage large terminase

scientific article

Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system

scientific article published in 2022

Structural framework for DNA translocation via the viral portal protein

scientific article

Structural investigation of transcriptional regulator HlyIIR: influence of a disordered region on protein fold and dimerization

scientific article

Structural rearrangements between portal protein subunits are essential for viral DNA translocation

scientific article published on 18 April 2007

Structure and Activity of a Novel Archaeal β-CASP Protein with N-Terminal KH Domains

scientific article

Structure of the Methanothermobacter thermautotrophicus exosome RNase PH ring

scientific article

Structure of the large terminase from a hyperthermophilic virus reveals a unique mechanism for oligomerization and ATP hydrolysis

scientific article published on 24 October 2017

Structure of the trp RNA-binding attenuation protein, TRAP, bound to RNA

scientific article

Structures of apo- and holo-tyrosine phenol-lyase reveal a catalytically critical closed conformation and suggest a mechanism for activation by K+ ions

scientific article published on June 2006

The crystal structure of Citrobacter freundii tyrosine phenol-lyase complexed with 3-(4'-hydroxyphenyl)propionic acid, together with site-directed mutagenesis and kinetic analysis, demonstrates that arginine 381 is required for substrate specificity

scientific article

The crystal structure of YloQ, a circularly permuted GTPase essential for Bacillus subtilis viability

scientific article

The crystal structure of unmodified tRNAPhe from Escherichia coli

scientific article published in July 2010

The interaction of RNA with TRAP: the role of triplet repeats and separating spacer nucleotides

scientific article published in April 2004

The neonatal phenotype of Prader-Willi syndrome

scientific article published on 01 June 2006

The polypeptide chain fold in tyrosine phenol-lyase, a pyridoxal-5'-phosphate-dependent enzyme

scientific article

The putative small terminase from the thermophilic dsDNA bacteriophage G20C is a nine-subunit oligomer

scientific article

The structure of trp RNA-binding attenuation protein

scientific article

The three-dimensional structure of human S100A12

scientific article

Thermostable virus portal proteins as reprogrammable adapters for solid-state nanopore sensors

scientific article published in Nature Communications

Transcription activator structure reveals redox control of a replication initiation reaction

scientific article

Trp RNA-Binding Attenuation Protein: Modifying Symmetry and Stability of a Circular Oligomer

scientific article

Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism

scientific article published on 18 January 2017

lin28 proteins promote expression of 17∼92 family miRNAs during amphibian development

scientific article published on 08 October 2015

List of works by Alfred Antson

11-fold symmetry of the trp RNA-binding attenuation protein (TRAP) from Bacillus subtilis determined by X-ray analysis

12-Fold symmetry of the putative portal protein from the Thermus thermophilus bacteriophage G20C determined by X-ray analysis

A flexible brace maintains the assembly of a hexameric replicative helicase during DNA unwinding

Anti-TRAP protein from Bacillus subtilis: crystallization and internal symmetry

Bacillus licheniformis Anti-TRAP can assemble into two types of dodecameric particles with the same symmetry but inverted orientation of trimers

Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners

Circular assemblies

Complexity in regulation of tryptophan biosynthesis in Bacillus subtilis

Conformational flexibility and molecular interactions of an archaeal homologue of the Shwachman-Bodian-Diamond syndrome protein

Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids

Cryo-EM structure in situ reveals a molecular switch that safeguards virus against genome loss

Crystal structure of Bacillus anthracis ThiI, a tRNA-modifying enzyme containing the predicted RNA-binding THUMP domain

Crystal structure of Bacillus cereus HlyIIR, a transcriptional regulator of the gene for pore-forming toxin hemolysin II.

Crystal structure of Bacillus subtilis anti-TRAP protein, an antagonist of TRAP/RNA interaction

Crystal structure of Mil (Mth680): internal duplication and similarity between the Imp4/Brix domain and the anticodon-binding domain of class IIa aminoacyl-tRNA synthetases

Crystal structure of tryptophanase

Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of human dihydrouridine synthase ⬇️

Crystallization and preliminary X-ray diffraction of Trypanosoma cruzi dUTPase

Crystallization and preliminary X-ray investigation of holotryptophanases from Escherichia coli and Proteus vulgaris.

Crystallographic Snapshots of Tyrosine Phenol-lyase Show That Substrate Strain Plays a Role in C–C Bond Cleavage

DNA recognition for virus assembly through multiple sequence-independent interactions with a helix-turn-helix motif.

Determination of interspin distances between spin labels attached to insulin: comparison of electron paramagnetic resonance data with the X-ray structure.

Dimerization of the human papillomavirus type 16 E2 N terminus results in DNA looping within the upstream regulatory region

Diversity and Host Interactions Among Virulent and Temperate Baltic Sea Flavobacterium Phages

Expression, crystallization and preliminary X-ray analysis of the E2 transactivation domain from papillomavirus type 16

Expression, purification, crystallization and preliminary X-ray studies of the TAN1 orthologue from Methanothermobacter thermautotrophicus

From bacterial to human dihydrouridine synthase: automated structure determination

Going for RNA repeats

How to Change the Oligomeric State of a Circular Protein Assembly: Switch from 11-Subunit to 12-Subunit TRAP Suggests a General Mechanism

Human Lin28 Forms a High-Affinity 1:1 Complex with the 106~363 Cluster miRNA miR-363.

Insights into the Catalytic Mechanism of Tyrosine Phenol-lyase from X-ray Structures of Quinonoid Intermediates

Interaction of the 11-subunit trp RNA-binding attenuation protein (TRAP) with its RNA target

Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues

Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases

Monomeric 14-3-3ζ has a chaperone-like activity and is stabilized by phosphorylated HspB6.

Papillomavirus E1 helicase assembly maintains an asymmetric state in the absence of DNA and nucleotide cofactors

Porphyrin-Assisted Docking of a Thermophage Portal Protein into Lipid Bilayers: Nanopore Engineering and Characterization.

Properties of the monomeric form of human 14-3-3ζ protein and its interaction with tau and HspB6.

Quantitative characterization of protein-protein complexes involved in base excision DNA repair

RNA protects a nucleoprotein complex against radiation damage

Recombinant portal protein from Staphylococcus epidermidis bacteriophage CNPH82 is a 13-subunit oligomer

Regulatory features of the trp operon and the crystal structure of the trp RNA-binding attenuation protein from Bacillus stearothermophilus

S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA

Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator

Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase

Structural basis for DNA recognition and loading into a viral packaging motor

Structural basis for DNA strand separation by a hexameric replicative helicase

Structural basis for the nuclease activity of a bacteriophage large terminase

Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system

Structural framework for DNA translocation via the viral portal protein

Structural investigation of transcriptional regulator HlyIIR: influence of a disordered region on protein fold and dimerization

Structural rearrangements between portal protein subunits are essential for viral DNA translocation

Structure and Activity of a Novel Archaeal β-CASP Protein with N-Terminal KH Domains

Structure of the Methanothermobacter thermautotrophicus exosome RNase PH ring

Structure of the large terminase from a hyperthermophilic virus reveals a unique mechanism for oligomerization and ATP hydrolysis

Structure of the trp RNA-binding attenuation protein, TRAP, bound to RNA

Structures of apo- and holo-tyrosine phenol-lyase reveal a catalytically critical closed conformation and suggest a mechanism for activation by K+ ions

The crystal structure of Citrobacter freundii tyrosine phenol-lyase complexed with 3-(4'-hydroxyphenyl)propionic acid, together with site-directed mutagenesis and kinetic analysis, demonstrates that arginine 381 is required for substrate specificity

The crystal structure of YloQ, a circularly permuted GTPase essential for Bacillus subtilis viability

The crystal structure of unmodified tRNAPhe from Escherichia coli

The interaction of RNA with TRAP: the role of triplet repeats and separating spacer nucleotides

The neonatal phenotype of Prader-Willi syndrome

The polypeptide chain fold in tyrosine phenol-lyase, a pyridoxal-5'-phosphate-dependent enzyme

The putative small terminase from the thermophilic dsDNA bacteriophage G20C is a nine-subunit oligomer

The structure of trp RNA-binding attenuation protein

The three-dimensional structure of human S100A12

Thermostable virus portal proteins as reprogrammable adapters for solid-state nanopore sensors

Transcription activator structure reveals redox control of a replication initiation reaction

Trp RNA-Binding Attenuation Protein: Modifying Symmetry and Stability of a Circular Oligomer

Viral genome packaging terminase cleaves DNA using the canonical RuvC-like two-metal catalysis mechanism

lin28 proteins promote expression of 17∼92 family miRNAs during amphibian development