List of works - Francesc Posas

Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 "two-component" osmosensor.

scientific article

Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK.

scientific article

Controlling gene expression in response to stress.

scientific article

Response to hyperosmotic stress

scientific article published on October 2012

The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes.

scientific article

Distributed biological computation with multicellular engineered networks

scientific article

Yeast Cdc42 GTPase and Ste20 PAK-like kinase regulate Sho1-dependent activation of the Hog1 MAPK pathway.

scientific article

Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress

scientific article

Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1.

scientific article

Dealing with osmostress through MAP kinase activation.

scientific article

The PPZ protein phosphatases are important determinants of salt tolerance in yeast cells.

scientific article

The MAPK Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast.

scientific article

Signal transduction by MAP kinase cascades in budding yeast

scientific article

The Stress-Activated Hog1 Kinase Is a Selective Transcriptional Elongation Factor for Genes Responding to Osmotic Stress

article

Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells

scientific article

The mRNA export factor Sus1 is involved in Spt/Ada/Gcn5 acetyltransferase-mediated H2B deubiquitinylation through its interaction with Ubp8 and Sgf11.

scientific article

Phosphorylation of Hsl1 by Hog1 leads to a G2 arrest essential for cell survival at high osmolarity

scientific article

Transient activation of the HOG MAPK pathway regulates bimodal gene expression.

scientific article

The yeast halotolerance determinant Hal3p is an inhibitory subunit of the Ppz1p Ser/Thr protein phosphatase.

scientific article

Control of Cdc28 CDK1 by a stress-induced lncRNA

scientific article

Biophysical properties of Saccharomyces cerevisiae and their relationship with HOG pathway activation

scientific article

The PPZ protein phosphatases are involved in the maintenance of osmotic stability of yeast cells

scientific article published on 01 March 1993

Control of cell cycle in response to osmostress: lessons from yeast.

scientific article published on January 2007

Cooperation between the INO80 complex and histone chaperones determines adaptation of stress gene transcription in the yeast Saccharomyces cerevisiae

scientific article

Coordinated control of replication and transcription by a SAPK protects genomic integrity.

scientific article

3D-printing of transparent bio-microfluidic devices in PEG-DA

scientific article published on 24 May 2016

Hog1 bypasses stress-mediated down-regulation of transcription by RNA polymerase II redistribution and chromatin remodeling

scientific article

Whole genome analysis of p38 SAPK-mediated gene expression upon stress.

scientific article

Time-dependent quantitative multicomponent control of the G₁-S network by the stress-activated protein kinase Hog1 upon osmostress

scientific article published in September 2011

The stress-activated protein kinase Hog1 mediates S phase delay in response to osmostress

scientific article published on 28 May 2009

Sir2 histone deacetylase prevents programmed cell death caused by sustained activation of the Hog1 stress-activated protein kinase

scientific article

The Hog1 SAPK controls the Rtg1/Rtg3 transcriptional complex activity by multiple regulatory mechanisms

scientific article published on 5 September 2012

The gene DIS2S1 is essential in Saccharomyces cerevisiae and is involved in glycogen phosphorylase activation

scientific article published on 01 May 1991

Expression of the HXT1 low affinity glucose transporter requires the coordinated activities of the HOG and glucose signalling pathways

scientific article published on 10 March 2004

Biochemical characterization of recombinant yeast PPZ1, a protein phosphatase involved in salt tolerance.

scientific article

Osmostress-induced gene expression--a model to understand how stress-activated protein kinases (SAPKs) regulate transcription

scientific article

Evolution of protein phosphorylation across 18 fungal species.

scientific article published in October 2016

Hog1 targets Whi5 and Msa1 transcription factors to downregulate cyclin expression upon stress.

scientific article

The N-Terminal Phosphorylation of RB by p38 Bypasses Its Inactivation by CDKs and Prevents Proliferation in Cancer Cells.

scientific article published on 14 September 2016

The Hog1 stress-activated protein kinase targets nucleoporins to control mRNA export upon stress

scientific article

A novel role for lncRNAs in cell cycle control during stress adaptation

scientific article published on September 28, 2014

A Synthetic Multicellular Memory Device.

scientific article published on 21 July 2016

Validation of regulated protein phosphorylation events in yeast by quantitative mass spectrometry analysis of purified proteins

scientific article published on 19 September 2012

H3K4 monomethylation dictates nucleosome dynamics and chromatin remodeling at stress-responsive genes

scientific article published on 26 March 2015

Sic1 plays a role in timing and oscillatory behaviour of B-type cyclins

scientific article published on 18 September 2011

Role of protein phosphatase 2A in the control of glycogen metabolism in yeast

scientific article published in April 1995

Saccharomyces cerevisiaegene SIT4 is involved in the control of glycogen metabolism

scientific article published on February 25, 1991

Mucins, osmosensors in eukaryotic cells?

scientific article published on 05 November 2007

Implementation of Complex Biological Logic Circuits Using Spatially Distributed Multicellular Consortia

scientific article published in February 2016

Control of cell cycle progression by the stress-activated Hog1 MAPK

scientific article published on 03 January 2005

List of works by Francesc Posas

Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 "two-component" osmosensor.

Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK.

Controlling gene expression in response to stress.

Response to hyperosmotic stress

The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes.

Distributed biological computation with multicellular engineered networks

Yeast Cdc42 GTPase and Ste20 PAK-like kinase regulate Sho1-dependent activation of the Hog1 MAPK pathway.

Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress

Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1.

Dealing with osmostress through MAP kinase activation.

The PPZ protein phosphatases are important determinants of salt tolerance in yeast cells.

The MAPK Hog1p modulates Fps1p-dependent arsenite uptake and tolerance in yeast.

Signal transduction by MAP kinase cascades in budding yeast

The Stress-Activated Hog1 Kinase Is a Selective Transcriptional Elongation Factor for Genes Responding to Osmotic Stress

Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells

The mRNA export factor Sus1 is involved in Spt/Ada/Gcn5 acetyltransferase-mediated H2B deubiquitinylation through its interaction with Ubp8 and Sgf11.

Phosphorylation of Hsl1 by Hog1 leads to a G2 arrest essential for cell survival at high osmolarity

Transient activation of the HOG MAPK pathway regulates bimodal gene expression.

The yeast halotolerance determinant Hal3p is an inhibitory subunit of the Ppz1p Ser/Thr protein phosphatase.

Control of Cdc28 CDK1 by a stress-induced lncRNA

Biophysical properties of Saccharomyces cerevisiae and their relationship with HOG pathway activation

The PPZ protein phosphatases are involved in the maintenance of osmotic stability of yeast cells

Control of cell cycle in response to osmostress: lessons from yeast.

Cooperation between the INO80 complex and histone chaperones determines adaptation of stress gene transcription in the yeast Saccharomyces cerevisiae

Coordinated control of replication and transcription by a SAPK protects genomic integrity.

3D-printing of transparent bio-microfluidic devices in PEG-DA

Hog1 bypasses stress-mediated down-regulation of transcription by RNA polymerase II redistribution and chromatin remodeling

Whole genome analysis of p38 SAPK-mediated gene expression upon stress.

Time-dependent quantitative multicomponent control of the G₁-S network by the stress-activated protein kinase Hog1 upon osmostress

The stress-activated protein kinase Hog1 mediates S phase delay in response to osmostress

Sir2 histone deacetylase prevents programmed cell death caused by sustained activation of the Hog1 stress-activated protein kinase

The Hog1 SAPK controls the Rtg1/Rtg3 transcriptional complex activity by multiple regulatory mechanisms

The gene DIS2S1 is essential in Saccharomyces cerevisiae and is involved in glycogen phosphorylase activation

Expression of the HXT1 low affinity glucose transporter requires the coordinated activities of the HOG and glucose signalling pathways

Biochemical characterization of recombinant yeast PPZ1, a protein phosphatase involved in salt tolerance.

Osmostress-induced gene expression--a model to understand how stress-activated protein kinases (SAPKs) regulate transcription

Evolution of protein phosphorylation across 18 fungal species.

Hog1 targets Whi5 and Msa1 transcription factors to downregulate cyclin expression upon stress.

The N-Terminal Phosphorylation of RB by p38 Bypasses Its Inactivation by CDKs and Prevents Proliferation in Cancer Cells.

The Hog1 stress-activated protein kinase targets nucleoporins to control mRNA export upon stress

A novel role for lncRNAs in cell cycle control during stress adaptation

A Synthetic Multicellular Memory Device.

Validation of regulated protein phosphorylation events in yeast by quantitative mass spectrometry analysis of purified proteins

H3K4 monomethylation dictates nucleosome dynamics and chromatin remodeling at stress-responsive genes

Sic1 plays a role in timing and oscillatory behaviour of B-type cyclins

Role of protein phosphatase 2A in the control of glycogen metabolism in yeast

Saccharomyces cerevisiaegene SIT4 is involved in the control of glycogen metabolism

Mucins, osmosensors in eukaryotic cells?

Implementation of Complex Biological Logic Circuits Using Spatially Distributed Multicellular Consortia

Control of cell cycle progression by the stress-activated Hog1 MAPK