List of works - Christopher Yau

A descriptive marker gene approach to single-cell pseudotime inference

scientific article published on 01 January 2019

A highly accurate platform for clone-specific mutation discovery enables the study of active mutational processes

scientific article published on 07 April 2020

A pan-cancer genome-wide analysis reveals tumour dependencies by induction of nonsense-mediated decay

scientific article

A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data

scientific article

Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo

scientific article

An atlas of genetic scores to predict multi-omic traits

scientific article published on 29 March 2023

Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion

scientific article published on 3 January 2013

Bayesian statistical learning for big data biology

scientific article published on 07 February 2019

CIDER: an interpretable meta-clustering framework for single-cell RNA-seq data integration and evaluation

scientific article published on 13 December 2021

CNV discovery using SNP genotyping arrays.

scientific article published on January 2008

Colorectal Cancer Cell Line Proteomes are Representative of Primary Tumors and Predict Drug Sensitivity

scientific article

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

scientific article

GenoSNP: a variational Bayes within-sample SNP genotyping algorithm that does not require a reference population.

scientific article published on 24 July 2008

Germline Mutations in PALB2, BRCA1, and RAD51C, Which Regulate DNA Recombination Repair, in Patients With Gastric Cancer

scientific article published on 23 December 2016

Hierarchical Bayesian nonparametric mixture models for clustering with variable relevance determination

scientific article published on July 2011

Immuno-phenotypes of Pancreatic Ductal Adenocarcinoma: Metaanalysis of transcriptional subtypes

NucleoFinder: a statistical approach for the detection of nucleosome positions.

scientific article

On the Utility of Graphics Cards to Perform Massively Parallel Simulation of Advanced Monte Carlo Methods ⬇️

scientific article published on December 1, 2010

OncoSNP-SEQ: a statistical approach for the identification of somatic copy number alterations from next-generation sequencing of cancer genomes

scientific article published on 7 August 2013

Order Under Uncertainty: Robust Differential Expression Analysis Using Probabilistic Models for Pseudotime Inference

scientific article

Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma

scientific article published on 15 July 2019

Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies.

scientific article published on 02 July 2016

Presynaptic NMDARs in the hippocampus facilitate transmitter release at theta frequency

scientific article published on December 2010

Probabilistic modeling of bifurcations in single-cell gene expression data using a Bayesian mixture of factor analyzers.

scientific article

QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data

scientific article

Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia ⬇️

scientific article published on January 19, 2012

Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche

scientific journal article

Separation of Dual Oxidase 2 and Lactoperoxidase Expression in Intestinal Crypts and Species Differences May Limit Hydrogen Peroxide Scavenging During Mucosal Healing in Mice and Humans

scientific article published in December 2017

Statistical Inference in Hidden Markov Models Using k-Segment Constraints

scientific article

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

scientific article published on 17 September 2013

The Hamming Ball Sampler

scientific article published on 3 September 2017

Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.

scientific article

Uncovering pseudotemporal trajectories with covariates from single cell and bulk expression data.

scientific article

ZIFA: Dimensionality reduction for zero-inflated single-cell gene expression analysis

scientific article

pcaReduce: hierarchical clustering of single cell transcriptional profiles

scientific article

switchde: inference of switch-like differential expression along single-cell trajectories

scientific article published on 23 December 2016

List of works by Christopher Yau

A descriptive marker gene approach to single-cell pseudotime inference

A highly accurate platform for clone-specific mutation discovery enables the study of active mutational processes

A pan-cancer genome-wide analysis reveals tumour dependencies by induction of nonsense-mediated decay

A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data

Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo

An atlas of genetic scores to predict multi-omic traits

Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion

Bayesian statistical learning for big data biology

CIDER: an interpretable meta-clustering framework for single-cell RNA-seq data integration and evaluation

CNV discovery using SNP genotyping arrays.

Colorectal Cancer Cell Line Proteomes are Representative of Primary Tumors and Predict Drug Sensitivity

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

GenoSNP: a variational Bayes within-sample SNP genotyping algorithm that does not require a reference population.

Germline Mutations in PALB2, BRCA1, and RAD51C, Which Regulate DNA Recombination Repair, in Patients With Gastric Cancer

Hierarchical Bayesian nonparametric mixture models for clustering with variable relevance determination

Immuno-phenotypes of Pancreatic Ductal Adenocarcinoma: Metaanalysis of transcriptional subtypes

NucleoFinder: a statistical approach for the detection of nucleosome positions.

On the Utility of Graphics Cards to Perform Massively Parallel Simulation of Advanced Monte Carlo Methods ⬇️

OncoSNP-SEQ: a statistical approach for the identification of somatic copy number alterations from next-generation sequencing of cancer genomes

Order Under Uncertainty: Robust Differential Expression Analysis Using Probabilistic Models for Pseudotime Inference

Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma

Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies.

Presynaptic NMDARs in the hippocampus facilitate transmitter release at theta frequency

Probabilistic modeling of bifurcations in single-cell gene expression data using a Bayesian mixture of factor analyzers.

QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data

Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia ⬇️

Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche

Separation of Dual Oxidase 2 and Lactoperoxidase Expression in Intestinal Crypts and Species Differences May Limit Hydrogen Peroxide Scavenging During Mucosal Healing in Mice and Humans

Statistical Inference in Hidden Markov Models Using k-Segment Constraints

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

The Hamming Ball Sampler

Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.

Uncovering pseudotemporal trajectories with covariates from single cell and bulk expression data.

ZIFA: Dimensionality reduction for zero-inflated single-cell gene expression analysis

pcaReduce: hierarchical clustering of single cell transcriptional profiles

switchde: inference of switch-like differential expression along single-cell trajectories