Search filters

List of works by Florian Markowetz

A phylogenetic latent feature model for clonal deconvolution ⬇️

article

A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes.

scientific article

A saltationist theory of cancer evolution

scientific article published in September 2016

A sparse regulatory network of copy-number driven expression reveals putative breast cancer oncogenes

Accumulated Metabolites of Hydroxybutyric Acid Serve as Diagnostic and Prognostic Biomarkers of Ovarian High-Grade Serous Carcinomas

scientific article published on 18 December 2015

Acetylcysteine for prevention of contrast nephropathy: meta-analysis

scientific article published in August 2003

All biology is computational biology.

scientific article

Allele-specific multi-sample copy number segmentation

Analyzing gene perturbation screens with nested effects models in R and bioconductor

scientific article published on 21 August 2008

BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes.

scientific article

BitPhylogeny: a probabilistic framework for reconstructing intra-tumor phylogenies

scientific article published on 13 February 2015

Cancer evolution: mathematical models and computational inference

scientific article

Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier

scientific article

Computational diagnostics with gene expression profiles.

scientific article

Computational identification of cellular networks and pathways

scientific article published on 14 May 2007

Copy number signatures and mutational processes in ovarian carcinoma

scientific article published on 13 August 2018

Decoding the Interdependence of Multiparametric Magnetic Resonance Imaging to Reveal Patient Subgroups Correlated with Survivals

scientific article published on 31 March 2019

Deregulation upon DNA damage revealed by joint analysis of context-specific perturbation data.

scientific article

Differential C3NET reveals disease networks of direct physical interactions

scientific article

Dissecting cancer heterogeneity--an unsupervised classification approach

scientific article published on September 2013

Diverse epigenetic strategies interact to control epidermal differentiation

scientific article

Evolutionary distances in the twilight zone--a rational kernel approach

scientific article

Five selfish reasons to work reproducibly

scientific article

Genome-wide Estrogen Receptor-alpha activation is sustained, not cyclical

Genome-wide Estrogen Receptor-α activation is sustained, not cyclical

scientific article published on 20 November 2018

GoIFISH: a system for the quantification of single cell heterogeneity from IFISH images

scientific article

How Subclonal Modeling Is Changing the Metastatic Paradigm

scientific article published on 18 November 2016

How to understand the cell by breaking it: network analysis of gene perturbation screens

scientific article

Immuno-phenotypes of Pancreatic Ductal Adenocarcinoma: Metaanalysis of transcriptional subtypes

Immunophenotypes of pancreatic ductal adenocarcinoma: Meta‐analysis of transcriptional subtypes

Inferring cellular networks--a review

scientific article

Inferring structural variant cancer cell fraction

scientific article published on 05 February 2020

Intra-tumor heterogeneity defines treatment-resistant HER2+ breast tumors

Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors

scholarly article by Inga H Rye et al published November 2018 in Molecular Oncology

Joining the dots: network analysis of gene perturbation data

article

KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice ⬇️

scientific article published on 01 August 2018

Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells

scientific article

Master Regulators of Oncogenic KRAS Response in Pancreatic Cancer: An Integrative Network Biology Analysis

scientific article

Master regulators of FGFR2 signalling and breast cancer risk

scientific article published on January 2013

Multi-omic machine learning predictor of breast cancer therapy response

scientific article published on 07 December 2021

Nested effects models for high-dimensional phenotyping screens

scientific article published in July 2007

Neutral tumor evolution?

scientific article

Non-transcriptional pathway features reconstructed from secondary effects of RNA interference

scientific article published on 13 September 2005

OncoNEM: inferring tumor evolution from single-cell sequencing data

scientific article

Parallel factor ChIP provides essential internal control for quantitative differential ChIP-seq

scientific article published on 17 April 2018

Patient-specific data fusion defines prognostic cancer subtypes

scientific article

Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study

scientific article

Penalized regression elucidates aberration hotspots mediating subtype-specific transcriptional responses in breast cancer

scientific article published on 30 July 2011

Phylogenetic quantification of intra-tumour heterogeneity

scientific article (publication date: April 2014)

Portraits of genetic intra-tumour heterogeneity and subclonal selection across cancer types

Posterior association networks and functional modules inferred from rich phenotypes of gene perturbations

scientific article

Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling

scientific article

Reconstructing evolving signalling networks by hidden Markov nested effects models ⬇️

RedeR: R/Bioconductor package for representing modular structures, nested networks and multiple levels of hierarchical associations.

scientific article

Regulators of genetic risk of breast cancer identified by integrative network analysis

scientific article

Reproducibility standards for machine learning in the life sciences

scientific article

SANTA: quantifying the functional content of molecular networks ⬇️

scientific article

SVclone: inferring structural variant cancer cell fraction

scientific article published on 4 August 2017

Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis

scientific article

Structure learning in Nested Effects Models

scientific article published in March 2008

Systems-level dynamic analyses of fate change in murine embryonic stem cells

scientific article

The evolutionary history of 2,658 cancers

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups ⬇️

scientific article (publication date: 18 April 2012)

The small molecule KHS101 induces bioenergetic dysfunction in glioblastoma cells through inhibition of mitochondrial HSPD1

scientific article published on 18 October 2017

Unraveling tumor-immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy

scientific article published on 01 June 2020

VULCAN: Network Analysis of ER-α activation reveals reprogramming of GRHL2

You Are Not Working for Me; I Am Working with You.

scientific article published on 24 September 2015

Paulina is supported by:

About Paulina

Help