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List of works by Ian M Hastings

A Two-Locus Model of the Evolution of Insecticide Resistance to Inform and Optimise Public Health Insecticide Deployment Strategies ⬇️

scientific article

Altering Antimalarial Drug Regimens May Dramatically Enhance and Restore Drug Effectiveness.

scientific article

Analysing malaria drug trials on a per‐individual or per‐clone basis: a comparison of methods ⬇️

scientific article published on December 19, 2012

Analysis of lines of mice selected on fat content: 4. Correlated responses in growth and reproduction ⬇️

scientific article published on 01 December 1991

Antibiotic chemotherapy of onchocerciasis: in a bovine model, killing of adult parasites requires a sustained depletion of endosymbiotic bacteria (Wolbachia species).

scientific article published on 14 September 2005

Antimalarial drugs and pregnancy: safety, pharmacokinetics, and pharmacovigilance.

scientific article published on February 2007

Climate prediction of El Niño malaria epidemics in north-west Tanzania

scientific article

Coartem (artemether-lumefantrine) in Africa: the beginning of the end?

scientific article published in October 2005

Complex dynamics and stability of resistance to antimalarial drugs.

scientific article published on 23 January 2006

Continued correspondence 'Will ART rollout in Africa drive an epidemic of drug-resistant HIV?'.

scientific article published in January 2007

Development, evaluation, and application of an in silico model for antimalarial drug treatment and failure.

scientific article

Entomological indices of malaria transmission in Chikhwawa district, Southern Malawi.

scientific article published on 21 November 2012

Environmental, pharmacological and genetic influences on the spread of drug-resistant malaria

scientific article published on 17 November 2010

Estimation of changes in genetic parameters in selected lines of mice using REML with an animal model. 1. Lean mass

scientific article published on October 1, 1992

Estimation of changes in genetic parameters in selected lines of mice using REML with an animal model. 2. Body weight, body composition and litter size

scientific article published on October 1, 1992

Field, genetic, and modeling approaches show strong positive selection acting upon an insecticide resistance mutation in Anopheles gambiae s.s.

scientific article published on 7 January 2010

Genetics and malaria--more questions than answers.

scientific article published in February 2001

How Robust Are Malaria Parasite Clearance Rates as Indicators of Drug Effectiveness and Resistance?

scientific article

How artemisinin-containing combination therapies slow the spread of antimalarial drug resistance ⬇️

scientific article published on February 1, 2011

Impaired fitness of drug-resistant malaria parasites: evidence and implication on drug-deployment policies.

scientific article published on June 2009

Improving Methods for Analyzing Antimalarial Drug Efficacy Trials: Molecular Correction Based on Length-Polymorphic Markers msp-1, msp-2, and glurp

scientific article published on 23 August 2019

Improving the role and contribution of pharmacokinetic analyses in antimalarial drug clinical trials.

scientific article published on 30 June 2014

Incorporating Stage-Specific Drug Action into Pharmacological Modeling of Antimalarial Drug Treatment

scientific article published on 22 February 2016

Incorporating genetic selection into individual-based models of malaria and other infectious diseases

scientific article published on 11 August 2020

Insecticide resistance evolution with mixtures and sequences: a model-based explanation

scientific article published on 15 February 2018

MalHaploFreq: a computer programme for estimating malaria haplotype frequencies from blood samples.

scientific article published on 15 July 2008

Malaria control and the evolution of drug resistance: an intriguing link.

scientific article published on February 2003

Markov chain Monte Carlo and expectation maximization approaches for estimation of haplotype frequencies for multiply infected human blood samples.

scientific article published on 25 August 2016

Mathematical models of human african trypanosomiasis epidemiology.

scientific article published on 11 February 2015

Measuring windows of selection for anti-malarial drug treatments

scientific article published on 31 July 2015

Modelling parasite drug resistance: lessons for management and control strategies.

scientific article

Modelling the impact of insecticide-based control interventions on the evolution of insecticide resistance and disease transmission

article

Molecular markers as indicators of antimalarial drug failure rates.

scientific article published on 22 October 2007

Mutation and selection within the individual

scientific article published on January 1, 1998

No room for complacency on drug resistance in Africa

scientific article published in Nature

Optimal Treatments for Severe Malaria and the Threat Posed by Artemisinin Resistance

scientific article published on 01 April 2019

Pharmacological considerations in the design of anti-malarial drug combination therapies - is matching half-lives enough?

scientific article published on 20 February 2014

Policy options for deploying anti-malarial drugs in endemic countries: a population genetics approach.

scientific article published on 17 December 2012

Population genetic aspects of deleterious cytoplasmic genomes and their effect on the evolution of sexual reproduction

scientific article published on 01 June 1992

Population genetics: XYZW as nature's language of love?

scientific article published on 01 April 2006

Prediction of hospital mortality from admission laboratory data and patient age: a simple model.

scientific article

Probability of emergence of antimalarial resistance in different stages of the parasite life cycle.

scientific article

Quantifying the pharmacology of antimalarial drug combination therapy.

scientific article published on 08 September 2016

Reply to "Parasite Strain, Host Immunity, and Circulating Blood Cells with Dead Parasites: Why Predicting Malaria Parasite Clearance Is Not a Simple Task".

scientific article published on 29 January 2016

Reproductive compensation and human genetic disease

scientific article published on 01 June 2001

The Importance of Scientific Debate in the Identification, Containment, and Control of Artemisinin Resistance

scientific article

The effect of testosterone in mice divergently selected on fat content or body weight ⬇️

scientific article published on 01 October 1997

The evolution of multiple drug resistance in malaria parasites ⬇️

scientific article published on March 1, 1998

The genetic polymorphism of Plasmodium vivax genes in endemic regions of Thailand.

scientific article published in December 2011

The impact of antimalarial drug resistance mutations on parasite fitness, and its implications for the evolution of resistance.

scientific article

The importance of modelling the spread of insecticide resistance in a heterogeneous environment: the example of adding synergists to bed nets

scientific article published on 2 August 2012

The importance of mosquito behavioural adaptations to malaria control in Africa.

scientific article published on 15 February 2013

The population genetics of alleles affecting enzyme activity

scientific article published on August 7, 1992

The role of windows of selection and windows of dominance in the evolution of insecticide resistance in human disease vectors

scientific article published on 10 December 2019

Tolerance is the key to understanding antimalarial drug resistance.

scientific article

Tsetse Control and Gambian Sleeping Sickness; Implications for Control Strategy.

scientific article published on 12 August 2015

Why is sex so frequent? ⬇️

scientific article published on 01 August 1992

Why we should effectively treat malaria.

scientific article published in February 2011

Will ART rollout in Africa drive an epidemic of drug resistant HIV?

article

ogaraK: a population genetics simulator for malaria.

scientific article published on 16 March 2011

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