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List of works by Boris C. Bastian

A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activity

scientific article published on 26 August 2015

A distinct subset of atypical Spitz tumors is characterized by BRAF mutation and loss of BAP1 expression

scientific article published in June 2012

A lymphohistiocytic variant of anaplastic large cell lymphoma with demonstration of the t(2;5)(p23;q35) chromosome translocation

scientific article published on 01 January 1998

A mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradation

scientific article

Absence of PDGFRA mutations in primary melanoma

scientific article published on 30 August 2007

Absence of somatic mutations of NEMO in keratoacanthoma

scientific article

Activating MET kinase rearrangements in melanoma and Spitz tumours

scientific article published on 27 May 2015

Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation

scientific article

Acute myeloid leukemia with t(14;21) involving RUNX1 and SYNE2: A novel favorable-risk translocation?

scientific article published on 31 July 2017

Adult rhabdomyoma of the lip

scientific article published on 01 February 1998

Allele-specific imbalance mapping identifies HDAC9 as a candidate gene for cutaneous squamous cell carcinoma.

scientific article published on 16 July 2013

Ambiguous melanocytic tumors with loss of 3p21.

scientific article

An isolated Merkel cell carcinoma metastasis at a distant cutaneous site presenting as a second 'primary' tumor.

scientific article published on 23 August 2011

An unconventional deep penetrating melanocytic nevus with microscopic involvement of regional lymph nodes

scientific article published in January 2012

Annexins in cancer and autoimmune diseases ⬇️

scientific article published on June 1, 1997

Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

scientific article

Assessment of Copy Number Status of Chromosomes 6 and 11 by FISH Provides Independent Prognostic Information in Primary Melanoma ⬇️

scientific article published on August 1, 2011

Atypical junctional melanocytic proliferations in benign lichenoid keratosis

scientific article published on 01 July 2003

Autoantibodies to annexins: a diagnostic marker for cutaneous disorders?

scientific article published on 01 December 1994

Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development

scientific article

CNVkit: Genome-Wide Copy Number Detection and Visualization from Targeted DNA Sequencing.

scientific article

Chromosomal aberrations in angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma unspecified: A matrix-based CGH approach

scientific article published on 01 January 2007

Chromosomal copy number analysis in melanoma diagnostics

scientific article published in January 2014

Clinical activity of the MEK inhibitor trametinib in metastatic melanoma containing BRAF kinase fusion

scientific article

Clinical, histopathologic, and genomic features of Spitz tumors with ALK fusions

scientific article

Clonal BRAF mutations in melanocytic nevi and initiating role of BRAF in melanocytic neoplasia

scientific article published on 20 May 2013

Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations

scientific article published on 21 October 2013

Comment on "Cutaneous melanoma in childhood and adolescence shows frequent loss of INK4A and gain of KIT"

scientific article published on 01 September 2010

Congenital uveal melanoma?

scientific article published on 12 August 2015

Constitutive activation of the phosphatidyl inositol 3 kinase signalling pathway in acral lentiginous melanoma

scientific article published on 10 November 2007

Consumption of the epidermis: a diagnostic criterion for the differential diagnosis of melanoma and Spitz nevus.

scientific article published on December 2004

Detection of elevated levels of IL-4, IL-6, and IL-10 in blister fluid of bullous pemphigoid

scientific article

Distinct senescence mechanisms restrain progression of dysplastic nevi

scientific article published in February 2024

Distinct sets of genetic alterations in melanoma

scientific article (publication date: 17 November 2005)

Dose-dependent, complete response to imatinib of a metastatic mucosal melanoma with a K642E KIT mutation

scientific article published on 29 May 2008

Dual inactivation of RB and p53 pathways in RAS-induced melanomas

scientific article published on March 2001

Efficacy and safety of nilotinib in patients with KIT-mutated metastatic or inoperable melanoma: final results from the global, single-arm, phase II TEAM trial

scientific article

Elevated cutaneous Smad activation associates with enhanced skin tumor susceptibility in organ transplant recipients

scientific article

Elevated levels of interleukin-8 in blister fluid of bullous pemphigoid compared with suction blisters of healthy control subjects

scientific article published on 01 February 1996

Eosinophilic globules in spitz nevi: no evidence for apoptosis

scientific article published on 01 December 1998

Erythropoietin receptor contributes to melanoma cell survival in vivo.

scientific article

Establishment of a novel melanoma cell line SMYM-PRGP showing cytogenetic and biological characteristics of the radial growth phase of acral melanomas.

scientific article published on 4 May 2007

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

scientific article

Expanding the genetic spectrum of pigmentation

scientific article published on 20 August 2007

Filling the gaps in the genomic catalogue of melanoma subtypes

scientific article

Fluorescence in situ hybridization (FISH) as an ancillary diagnostic tool in the diagnosis of melanoma

scientific article published in August 2009

Fluorescence in situ hybridization as an ancillary tool in the diagnosis of ambiguous melanocytic neoplasms: a review of 804 cases

scientific article published on June 2014

Frequent mutations in the MITF pathway in melanoma

scientific article published on 29 April 2009

Frequent p16-independent inactivation of p14ARF in human melanoma

scientific article published on 27 May 2008

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

scientific article

From melanocytes to melanomas.

scientific article published on 29 April 2016

Functional characterization of uveal melanoma oncogenes

scientific article published on 01 December 2020

Fusion partners of NTRK3 affect subcellular localization of the fusion kinase and cytomorphology of melanocytes

scientific article published on 23 September 2020

GNAQ and GNA11 mutations in melanocytomas of the central nervous system

scientific article

Genetic and molecular characterization of uveal melanoma cell lines ⬇️

scientific article published on February 2, 2012

Genetic changes in neoplasms arising in congenital melanocytic nevi: differences between nodular proliferations and melanomas

scientific article published on October 2002

Genome-wide associations studies for melanoma and nevi

scientific article

Genomic analysis of blue nevi and related dermal melanocytic proliferations.

scientific article published on September 2005

Genomic analysis of melanocytic neoplasia.

scientific article

Genomic profiling of malignant peritoneal mesothelioma reveals recurrent alterations in epigenetic regulatory genes BAP1, SETD2, and DDX3X.

scientific article

Genomic profiling of malignant phyllodes tumors reveals aberrations in FGFR1 and PI-3 kinase/RAS signaling pathways and provides insights into intratumoral heterogeneity.

scientific article

Germline Variation Controls the Architecture of Somatic Alterations in Tumors ⬇️

scientific article published on September 23, 2010

Germline mutations in BAP1 predispose to melanocytic tumors

scientific article

Germline variation of the melanocortin-1 receptor does not explain shared risk for melanoma and thyroid cancer.

scientific article

Giant cell fibroblastoma. A rare soft tissue tumor in childhood

scientific article published in April 1996

Human tumor genomics and zebrafish modeling identify loss as a driver of mucosal melanoma

scientific article published in Science

Hypothesis: a role for telomere crisis in spontaneous regression of melanoma

scientific article published on 01 May 2003

Improving melanoma classification by integrating genetic and morphologic features

scientific article

In melanoma, Hippo signaling is affected by copy number alterations and YAP1 overexpression impairs patient survival.

scientific article

In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling

scientific article published on October 2006

Inactivating MUTYH germline mutations in pediatric patients with high-grade midline gliomas.

scientific article published on 21 February 2016

Interactive system for registering adjacent tissue sections

Interleukin-10 production in malignant melanoma: preferential detection of IL-10-secreting tumor cells in metastatic lesions

scientific article published on 01 May 1996

KIT as a therapeutic target in melanoma.

scientific article

KIT as a therapeutic target in metastatic melanoma

scientific article published on June 2011

Kinase fusions are frequent in Spitz tumours and spitzoid melanomas

scientific article

Localization of annexins in normal and diseased human skin

scientific article

Loss of the p53/p63 Regulated Desmosomal Protein Perp Promotes Tumorigenesis ⬇️

scientific article published on October 21, 2010

Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma

scientific article

MC1R germline variants confer risk for BRAF-mutant melanoma

scientific article published on 29 June 2006

MC1R variants increase risk of melanomas harboring BRAF mutations.

scientific article

Melanocytic tumors with MAP3K8 fusions: report of 33 cases with morphological-genetic correlations

scientific article published on 12 November 2019

Melanoma BRAF fusions--letter

scientific article published in December 2014

Melanoma from bench to bedside: meeting report from the 6th international melanoma congress

scientific article published on 17 December 2009

Metastatic melanoma in association with a giant congenital melanocytic nevus in an adult: controversial CGH findings

scientific article published in June 2015

Metastatic melanoma with striking adenocarcinomatous differentiation illustrating phenotypic plasticity in melanoma

scientific article published in September 2011

Microcystic adnexal carcinoma of the skin. An underestimated tumor

scientific article published in April 1996

Molecular analysis of a case of nevus of ota showing progressive evolution to melanoma with intermediate stages resembling cellular blue nevus

scientific article published in May 2010

Molecular cytogenetic analysis of Spitz nevi shows clear differences to melanoma

scientific article published on December 1999

Molecular genetics of melanocytic neoplasia: practical applications for diagnosis

scientific article published in October 2004

Molecular-microscopical correlation in dermatopathology

scientific article published on April 2011

Multiple Merkel cell carcinomas: Late metastasis or multiple primary tumors? A molecular study

scientific article published on 20 March 2017

Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP

scientific article

Mutations in GNA11 in uveal melanoma

scientific article

Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism

scientific article

NTRK3 kinase fusions in Spitz tumours

scientific article published on August 2016

Nodular lesions arising in a large congenital melanocytic naevus in a newborn with eruptive disseminated Spitz naevi

scientific article published on 01 November 2011

Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution.

scientific article published on 13 March 2017

Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma.

scientific article published on 04 August 2009

Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells

scientific article published on June 2013

PI3-kinase subunits are infrequent somatic targets in melanoma.

scientific article published on 13 April 2006

Persistent (recurrent) Spitz nevi: a histopathologic, immunohistochemical, and molecular pathologic study of 22 cases

scientific article

Pervasive chromosomal instability and karyotype order in tumour evolution

scientific article published on 02 September 2020

Phase II Study of Nilotinib in Melanoma Harboring KIT Alterations Following Progression to Prior KIT Inhibition

scientific article published on 18 February 2015

Phospholipase A2 is secreted by murine keratinocytes after stimulation with IL-1 alpha and TNF-alpha

scientific article published on 01 March 1996

Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination.

scientific article

Preoperative characterization of pigmented skin lesions by epiluminescence microscopy and high-frequency ultrasound

scientific article published in March 1995

Primary cutaneous natural killer/T-cell lymphoma

scientific article published on 01 January 1998

Primary neuroendocrine carcinoma of the skin with an unusual follicular lymphocytic infiltrate of the dermis

scientific article published on 01 December 1996

RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma.

scientific article

Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy

scientific article

Regulatory network decoded from epigenomes of surface ectoderm-derived cell types

scientific article

SOX10 ablation arrests cell cycle, induces senescence, and suppresses melanomagenesis

scientific article published on August 2013

Somatic activation of KIT in distinct subtypes of melanoma

scientific article

Somatic mutation of epidermal growth factor receptor in a small subset of cutaneous squamous cell carcinoma.

scientific article

Spitz melanoma is a distinct subset of spitzoid melanoma

scientific article published on 03 January 2020

Sporadic naturally occurring melanoma in dogs as a preclinical model for human melanoma

scientific article

Sunitinib therapy for melanoma patients with KIT mutations

scientific article

Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.

scientific article

Targeting activated KIT signaling for melanoma therapy.

scientific article published on 12 August 2013

The Genetic Evolution of Melanoma

scientific article published on 01 March 2016

The Genetic Evolution of Melanoma from Precursor Lesions

scientific article published in November 2015

The combination of axitinib followed by paclitaxel/carboplatin yields extended survival in advanced BRAF wild-type melanoma: results of a clinical/correlative prospective phase II clinical trial

scientific article

The genetic evolution of metastatic uveal melanoma

scientific article published on 28 June 2019

The genomic landscapes of individual melanocytes from human skin

scientific article published on 07 October 2020

The longer your telomeres, the larger your nevus?

scientific article

The melanomas: a synthesis of epidemiological, clinical, histopathological, genetic, and biological aspects, supporting distinct subtypes, causal pathways, and cells of origin ⬇️

scientific article published on August 16, 2011

The molecular pathology of melanoma: an integrated taxonomy of melanocytic neoplasia

scientific article published on January 2014

The presence of polyomavirus in non-melanoma skin cancer in organ transplant recipients is rare.

scientific article published on 24 July 2008

The prevalence and prognostic value of BRAF mutation in thyroid cancer

scientific article

The state of melanoma: challenges and opportunities

scientific article

The tumor suppressor BAP1 cooperates with BRAFV600E to promote tumor formation in cutaneous melanoma

scientific article published on 24 September 2018

Two cases of unusual acral melanocytic tumors: illustration of molecular cytogenetics as a diagnostic tool

scientific article published in January 2003

Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets

scientific article published on 18 July 2019

[Benign giant cell tumor of the tendon sheath. A differential diagnosis of cutaneous tumors near the joint]

scientific article published on 01 June 1994

[DNA copy number changes in the diagnosis of melanocytic tumors]

scientific article published on 01 November 2007

[Is acrolentiginous melanoma (ALM) more malignant than superficially spreading melanoma (SSM) at a high-risk site? A matched-pair comparison between 113 ALM and SSM within the scope of a multicenter study]

scientific article published on 01 August 1994

[Pilomatrix carcinoma in an unusual location. Case report and review of the literature]

scientific article published on 01 May 1999

[Prognostic advantage for defined risk groups by lymphocyte dissection. Long-term study of 3,616 melanoma patients]

scientific article published on 01 September 1994

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