List of works - Nenad Bursac

A computer model of engineered cardiac monolayers.

scientific article

A method to measure myocardial calcium handling in adult Drosophila

scientific article

A method to replicate the microstructure of heart tissue in vitro using DTMRI-based cell micropatterning

scientific article published on 06 October 2009

Acceleration of functional reentry by rapid pacing in anisotropic cardiac monolayers: formation of multi-wave functional reentries

scientific article published on 7 November 2005

Adjunctive β2-agonist treatment reduces glycogen independently of receptor-mediated acid α-glucosidase uptake in the limb muscles of mice with Pompe disease

scientific article published on 21 January 2014

Age-dependent functional crosstalk between cardiac fibroblasts and cardiomyocytes in a 3D engineered cardiac tissue

scientific article published on 25 April 2017

Altering integrin engagement regulates membrane localization of Kir2.1 channels

scientific article published on 02 September 2019

Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs

scientific article published on 9 January 2015

Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo

scientific article

Calcium dependent CAMTA1 in adult stem cell commitment to a myocardial lineage ⬇️

scientific article published on June 8, 2012

Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes

scientific article published on 28 May 2009

Cardiac fibroblasts in pressure overload hypertrophy: the enemy within? ⬇️

scientific article

Cardiomyoplasty: the prospect of human stem cells

scientific article published in May 2005

Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues.

scientific article published on 19 February 2016

Characterizing functional stem cell-cardiomyocyte interactions.

scientific article published on January 2010

Collision-based spiral acceleration in cardiac media: roles of wavefront curvature and excitable gap.

scientific article

Colonizing the heart from the epicardial side ⬇️

scientific article published on April 30, 2012

Conduction block in micropatterned cardiomyocyte cultures replicating the structure of ventricular cross-sections

scientific article published on 09 November 2011

Controlling the structural and functional anisotropy of engineered cardiac tissues

scientific article

Cultivation in rotating bioreactors promotes maintenance of cardiac myocyte electrophysiology and molecular properties

scientific article published in December 2003

Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing

scientific article

Design, evaluation, and application of engineered skeletal muscle

scientific article published on 5 October 2015

Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues

scientific article

Distilling complexity to advance cardiac tissue engineering

scientific article

Dynamic culture yields engineered myocardium with near-adult functional output.

scientific article published on 30 September 2016

Electrical pacing counteracts intrinsic shortening of action potential duration of neonatal rat ventricular cells in culture

scientific article published in September 2006

Electrotonic loading of anisotropic cardiac monolayers by unexcitable cells depends on connexin type and expression level

scientific article published on 03 June 2009

Engineering biosynthetic excitable tissues from unexcitable cells for electrophysiological and cell therapy studies.

scientific article

Engineering prokaryotic channels for control of mammalian tissue excitability

scientific article published on 18 October 2016

Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts

scientific journal article

Functional Cardiac Tissue Engineering ⬇️

scientific article published on March 1, 2012

Genetic engineering and stem cells: combinatorial approaches for cardiac cell therapy

scientific article published on May 2008

Genetic engineering of somatic cells to study and improve cardiac function ⬇️

scientific article published on November 1, 2012

Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair.

scientific article

Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts

scientific article

Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues

scientific article

Introduction to the special issue on tissue engineering and regenerative medicine

scientific article published on July 2014

Local Tissue Geometry Determines Contractile Force Generation of Engineered Muscle Networks ⬇️

scientific article published on January 4, 2012

Mechanoelectrical excitation by fluid jets in monolayers of cultured cardiac myocytes

scientific article published on 24 February 2005

Mesoscopic hydrogel molding to control the 3D geometry of bioartificial muscle tissues

scientific article

Microheterogeneity-induced conduction slowing and wavefront collisions govern macroscopic conduction behavior: A computational and experimental study.

scientific article published on 16 July 2018

Modeling an Excitable Biosynthetic Tissue with Inherent Variability for Paired Computational-Experimental Studies

scientific article

Multiarm spirals in a two-dimensional cardiac substrate.

scholarly article

Novel anisotropic engineered cardiac tissues: studies of electrical propagation.

scientific article published on 2 August 2007

Novel micropatterned cardiac cell cultures with realistic ventricular microstructure.

scientific article published in May 2009

Physiology and metabolism of tissue-engineered skeletal muscle

scientific article

Quantifying electrical interactions between cardiomyocytes and other cells in micropatterned cell pairs.

scientific article published in January 2014

Rapid fusion between mesenchymal stem cells and cardiomyocytes yields electrically active, non-contractile hybrid cells

scientific article

Reflective interferometric chamber for quantitative phase imaging of biological sample dynamics

scientific article published on May 2010

Robust T-tubulation and maturation of cardiomyocytes using tissue-engineered epicardial mimetics.

scientific article

Roles of adherent myogenic cells and dynamic culture in engineered muscle function and maintenance of satellite cells

scientific article

STIM1-Ca2+ signaling modulates automaticity of the mouse sinoatrial node.

scientific article

Single-detector simultaneous optical mapping of V(m) and [Ca(2+)](i) in cardiac monolayers.

scientific article published on 29 November 2011

Size and ionic currents of unexcitable cells coupled to cardiomyocytes distinctly modulate cardiac action potential shape and pacemaking activity in micropatterned cell pairs

scientific article

Sodium channel kinetic changes that produce Brugada syndrome or progressive cardiac conduction system disease.

scientific article published on 28 July 2006

Soluble miniagrin enhances contractile function of engineered skeletal muscle ⬇️

scientific article published on November 10, 2011

Spatial profiles of electrical mismatch determine vulnerability to conduction failure across a host-donor cell interface

scientific article

Stoichiometry of Gata4, Mef2c, and Tbx5 influences the efficiency and quality of induced cardiac myocyte reprogramming

scientific article published on 21 November 2014

Striated muscle function, regeneration, and repair

scientific article

Structural coupling of cardiomyocytes and noncardiomyocytes: quantitative comparisons using a novel micropatterned cell pair assay.

scientific article published on 23 May 2008

Synergizing Engineering and Biology to Treat and Model Skeletal Muscle Injury and Disease.

scientific article published on December 2015

System identification of dynamic closed-loop control of total peripheral resistance by arterial and cardiopulmonary baroreceptors ⬇️

scientific article published on 01 August 2001

The extracellular matrix protein agrin promotes heart regeneration in mice

scientific article published on 5 June 2017

The role of extracellular matrix composition in structure and function of bioengineered skeletal muscle

scientific article

The role restitution in pacing induced spiral wave acceleration

scientific article published on 01 January 2006

Tissue-engineered 3-dimensional (3D) microenvironment enhances the direct reprogramming of fibroblasts into cardiomyocytes by microRNAs

scientific article published on 12 December 2016

Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes

scientific article

Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming

scientific article

Use of flow, electrical, and mechanical stimulation to promote engineering of striated muscles

scientific article

WNT3 is a biomarker capable of predicting the definitive endoderm differentiation potential of hESCs

scientific article published on 4 June 2013

Whole-cell-analysis of live cardiomyocytes using wide-field interferometric phase microscopy

scientific article

X-linked inhibitor of apoptosis protein-mediated attenuation of apoptosis, using a novel cardiac-enhanced adeno-associated viral vector.

scientific article

List of works by Nenad Bursac

A computer model of engineered cardiac monolayers.

A method to measure myocardial calcium handling in adult Drosophila

A method to replicate the microstructure of heart tissue in vitro using DTMRI-based cell micropatterning

Acceleration of functional reentry by rapid pacing in anisotropic cardiac monolayers: formation of multi-wave functional reentries

Adjunctive β2-agonist treatment reduces glycogen independently of receptor-mediated acid α-glucosidase uptake in the limb muscles of mice with Pompe disease

Age-dependent functional crosstalk between cardiac fibroblasts and cardiomyocytes in a 3D engineered cardiac tissue

Altering integrin engagement regulates membrane localization of Kir2.1 channels

Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs

Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo

Calcium dependent CAMTA1 in adult stem cell commitment to a myocardial lineage ⬇️

Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes

Cardiac fibroblasts in pressure overload hypertrophy: the enemy within? ⬇️

Cardiomyoplasty: the prospect of human stem cells

Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues.

Characterizing functional stem cell-cardiomyocyte interactions.

Collision-based spiral acceleration in cardiac media: roles of wavefront curvature and excitable gap.

Colonizing the heart from the epicardial side ⬇️

Conduction block in micropatterned cardiomyocyte cultures replicating the structure of ventricular cross-sections

Controlling the structural and functional anisotropy of engineered cardiac tissues

Cultivation in rotating bioreactors promotes maintenance of cardiac myocyte electrophysiology and molecular properties

Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing

Design, evaluation, and application of engineered skeletal muscle

Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues

Distilling complexity to advance cardiac tissue engineering

Dynamic culture yields engineered myocardium with near-adult functional output.

Electrical pacing counteracts intrinsic shortening of action potential duration of neonatal rat ventricular cells in culture

Electrotonic loading of anisotropic cardiac monolayers by unexcitable cells depends on connexin type and expression level

Engineering biosynthetic excitable tissues from unexcitable cells for electrophysiological and cell therapy studies.

Engineering prokaryotic channels for control of mammalian tissue excitability

Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts

Functional Cardiac Tissue Engineering ⬇️

Genetic engineering and stem cells: combinatorial approaches for cardiac cell therapy

Genetic engineering of somatic cells to study and improve cardiac function ⬇️

Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair.

Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts

Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues

Introduction to the special issue on tissue engineering and regenerative medicine

Local Tissue Geometry Determines Contractile Force Generation of Engineered Muscle Networks ⬇️

Mechanoelectrical excitation by fluid jets in monolayers of cultured cardiac myocytes

Mesoscopic hydrogel molding to control the 3D geometry of bioartificial muscle tissues

Microheterogeneity-induced conduction slowing and wavefront collisions govern macroscopic conduction behavior: A computational and experimental study.

Modeling an Excitable Biosynthetic Tissue with Inherent Variability for Paired Computational-Experimental Studies

Multiarm spirals in a two-dimensional cardiac substrate.

Novel anisotropic engineered cardiac tissues: studies of electrical propagation.

Novel micropatterned cardiac cell cultures with realistic ventricular microstructure.

Physiology and metabolism of tissue-engineered skeletal muscle

Quantifying electrical interactions between cardiomyocytes and other cells in micropatterned cell pairs.

Rapid fusion between mesenchymal stem cells and cardiomyocytes yields electrically active, non-contractile hybrid cells

Reflective interferometric chamber for quantitative phase imaging of biological sample dynamics

Robust T-tubulation and maturation of cardiomyocytes using tissue-engineered epicardial mimetics.

Roles of adherent myogenic cells and dynamic culture in engineered muscle function and maintenance of satellite cells

STIM1-Ca2+ signaling modulates automaticity of the mouse sinoatrial node.

Single-detector simultaneous optical mapping of V(m) and [Ca(2+)](i) in cardiac monolayers.

Size and ionic currents of unexcitable cells coupled to cardiomyocytes distinctly modulate cardiac action potential shape and pacemaking activity in micropatterned cell pairs

Sodium channel kinetic changes that produce Brugada syndrome or progressive cardiac conduction system disease.

Soluble miniagrin enhances contractile function of engineered skeletal muscle ⬇️

Spatial profiles of electrical mismatch determine vulnerability to conduction failure across a host-donor cell interface

Stoichiometry of Gata4, Mef2c, and Tbx5 influences the efficiency and quality of induced cardiac myocyte reprogramming

Striated muscle function, regeneration, and repair

Structural coupling of cardiomyocytes and noncardiomyocytes: quantitative comparisons using a novel micropatterned cell pair assay.

Synergizing Engineering and Biology to Treat and Model Skeletal Muscle Injury and Disease.

System identification of dynamic closed-loop control of total peripheral resistance by arterial and cardiopulmonary baroreceptors ⬇️

The extracellular matrix protein agrin promotes heart regeneration in mice

The role of extracellular matrix composition in structure and function of bioengineered skeletal muscle

The role restitution in pacing induced spiral wave acceleration

Tissue-engineered 3-dimensional (3D) microenvironment enhances the direct reprogramming of fibroblasts into cardiomyocytes by microRNAs

Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes

Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming

Use of flow, electrical, and mechanical stimulation to promote engineering of striated muscles

WNT3 is a biomarker capable of predicting the definitive endoderm differentiation potential of hESCs

Whole-cell-analysis of live cardiomyocytes using wide-field interferometric phase microscopy

X-linked inhibitor of apoptosis protein-mediated attenuation of apoptosis, using a novel cardiac-enhanced adeno-associated viral vector.