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List of works by Paul J. McLaren

A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis ⬇️

scientific article published on 21 December 2016

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control

scientific article published on 29 October 2013

A genome-wide association study of resistance to HIV infection in highly exposed uninfected individuals with hemophilia A.

scientific article published on 30 January 2013

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

A novel Acute Retroviral Syndrome Severity Score predicts the key surrogate markers for HIV-1 disease progression

scientific article

Additive effects of HLA alleles and innate immune genes determine viral outcome in HCV infection

scientific article published on 4 July 2014

Amino Acid Variation in HLA Class II Proteins Is a Major Determinant of Humoral Response to Common Viruses

scientific article

Analysis of stop-gain and frameshift variants in human innate immunity genes

scientific article

Antigen-specific gene expression profiles of peripheral blood mononuclear cells do not reflect those of T-lymphocyte subsets

scientific article published on September 2004

Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls

scientific article

Author Correction: CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome

scientific article published on 01 November 2019

CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome

scientific article published on 17 June 2019

CYFIP2 is highly abundant in CD4+ cells from multiple sclerosis patients and is involved in T cell adhesion

scientific article

Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

scientific article

Corrigendum: Exome Sequencing Reveals Primary Immunodeficiencies in Children with Community-Acquired Pseudomonas aeruginosa Sepsis.

scientific article published on 27 October 2016

Decreased immune activation in resistance to HIV-1 infection is associated with an elevated frequency of CD4(+)CD25(+)FOXP3(+) regulatory T cells

scientific article published in May 2009

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Disentangling human tolerance and resistance against HIV.

scientific article

Estimating the Respective Contributions of Human and Viral Genetic Variation to HIV Control

scientific article

European genetic diversity and susceptibility to pathogens

scientific article published on January 2013

Exome Sequencing Reveals Primary Immunodeficiencies in Children with Community-Acquired Pseudomonas aeruginosa Sepsis

scientific article published on 20 September 2016

Exome sequencing and the genetic basis of complex traits

scientific article published on 29 May 2012

Expansion of cytotoxic tissue-resident CD8+ T cells and CCR6+CD161+ CD4+ T cells in the nasal mucosa following mRNA COVID-19 vaccination

scientific article published in 2022

Extremely low-coverage sequencing and imputation increases power for genome-wide association studies

scientific article published on 20 May 2012

Fine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African Americans

scientific article

Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease

scientific article

Genetic predictors of cervical dysplasia in African American HIV-infected women: ACTG DACS 268.

scientific article

Genome-Wide Association Study of Human Immunodeficiency Virus (HIV)-1 Coreceptor Usage in Treatment-Naive Patients from An AIDS Clinical Trials Group Study

scientific article

Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.

scientific article

Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants

scientific article published on December 2012

Genome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols

scientific article

Genomewide association study of atazanavir pharmacokinetics and hyperbilirubinemia in AIDS Clinical Trials Group protocol A5202.

scientific article

Genomic approaches to the study of HIV‐1 acquisition

scientific article

Guanylate Binding Protein (GBP) 5 Is an Interferon-Inducible Inhibitor of HIV-1 Infectivity

scientific article published on 15 March 2016

GuavaH: a compendium of host genomic data in HIV biology and disease

scientific article

HIV Peptidome-Wide Association Study Reveals Patient-Specific Epitope Repertoires Associated with HIV Control

article

HIV and innate immunity - a genomics perspective

scientific article published on August 2013

HIV peptidome-wide association study reveals patient-specific epitope repertoires associated with HIV control

scientific article published on 02 January 2019

HIV-1 capture and transmission by dendritic cells: the role of viral glycolipids and the cellular receptor Siglec-1

scientific article published on 17 July 2014

HIV‐exposed seronegative commercial sex workers show a quiescent phenotype in the CD4+ T cell compartment and reduced expression of HIV‐dependent host factors

scientific article

HLA class I and KIR genes do not protect against HIV type 1 infection in highly exposed uninfected individuals with hemophilia A.

scientific article

Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans

scientific article published on 14 April 2016

Human genetic variation in HIV disease: beyond genome-wide association studies

scientific article

Identification of Siglec-1 null individuals infected with HIV-1.

scientific article published on 11 August 2016

Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses

scientific article published on 16 May 2015

Increased CHIP Prevalence Amongst People Living with HIV

scientific article published on 07 November 2020

Influence of HLA-C expression level on HIV control

scientific article published on April 2013

Microarray analysis of HIV resistant female sex workers reveal a gene expression signature pattern reminiscent of a lowered immune activation state

scientific article

Minding the gap in HIV host genetics: opportunities and challenges

scientific article published on 14 May 2020

No Evidence for Association of β-Defensin Genomic Copy Number with HIV Susceptibility, HIV Load during Clinical Latency, or Progression to AIDS.

scientific article published on January 2017

On stand by: host genetics of HIV control.

scientific article

Polymorphisms in IRF-1 associated with resistance to HIV-1 infection in highly exposed uninfected Kenyan sex workers

scientific article

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

scientific article

Privacy-preserving genomic testing in the clinic: a model using HIV treatment.

scientific article published on 14 January 2016

Severe viral respiratory infections in children with IFIH1 loss-of-function mutations.

scientific article

Susceptibility and adaptation to human TRIM5α alleles at positive selected sites in HIV-1 capsid

scientific article published on 17 April 2013

Systemic inflammation before and after antiretroviral therapy initiation as a predictor of immune response among HIV-infected individuals in Manitoba

scientific article published on 21 December 2016

The Characteristics of Heterozygous Protein Truncating Variants in the Human Genome

scientific article published on 7 December 2015

The impact of host genetic variation on infection with HIV-1.

scientific article

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

scientific article

The role of regulatory T cells in chronic and acute viral infections

scientific article published on April 2008

Vitamin D time profile based on the contribution of non-genetic and genetic factors in HIV-infected individuals of European ancestry

scientific article published on 17 July 2014

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