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List of works by David Cowburn

13C NMR Assignments of the Protonated Carbons of [d(TAGCGCTA)]2by Two-Dimensional Proton-Detected Heteronuclear Correlation

A cell-penetrating helical peptide as a potential HIV-1 inhibitor

scientific article

A conformational switch in the scaffolding protein NHERF1 controls autoinhibition and complex formation

scientific article

A full-length group 1 bacterial sigma factor adopts a compact structure incompatible with DNA binding

scientific article published on October 2008

A never ending frontier

scientific article published on 01 October 1997

A novel, specific interaction involving the Csk SH3 domain and its natural ligand

scientific article

A peptide mimic blocks the cross-reaction of anti-DNA antibodies with glomerular antigens

scientific article

A promiscuous split intein with expanded protein engineering applications

scientific article

A rapid, efficient synthesis of oxytocin and 8-arginine-vasopressin. Comparison of benzyl, p-methoxybenzyl, and p-methylbenzyl as protecting groups for cysteine

scientific article

A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein

scientific article published on 16 October 1995

A ubiquitin-interacting motif from Hrs binds to and occludes the ubiquitin surface necessary for polyubiquitination in monoubiquitinated proteins

scientific article

Abl kinase constructs expressed in bacteria: facilitation of structural and functional studies including segmental labeling by expressed protein ligation

scientific article published on 16 May 2012

Accurate quantitation of protein expression and site-specific phosphorylation

scientific article

Accurate sampling of high-frequency motions in proteins by steady-state (15)N-{(1)H} nuclear Overhauser effect measurements in the presence of cross-correlated relaxation

scientific article published on May 2009

Adaptors and integrators

scientific article published on September 1996

Affinity and specificity requirements for the first Src homology 3 domain of the Crk proteins

scientific article

Affinity labeling of the acetylcholine receptor in the electroplax: electrophoretic separtion in sodium dodecyl sulfate.

scientific article

Allosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1

scientific article

An Approach to Direct Determination of Protein Dynamics from15N NMR Relaxation at Multiple Fields, Independent of Variable15N Chemical Shift Anisotropy and Chemical Exchange Contributions

article

An Atypical Mechanism of Split Intein Molecular Recognition and Folding

scientific article published on 10 September 2018

An Investigation of the Conformation of Bovine alpha-Lactalbumin by Proton Magnetic Resonance and Optical Spectroscopy

scientific article published on 01 May 1970

An ab initio study of intermolecular hydrogen bonding between small peptide fragments

An analysis of the circular dichroism of the lysozyme- -lactalbumin group of proteins

scientific article published in March 1972

Analysis of Multivalent IDP Interactions: Stoichiometry, Affinity, and Local Concentration Effect Measurements

scientific article published on 01 January 2020

Anomalous exchange kinetics of peptide amide protons in aqueous solutions

Anti-DNA antibody mediated catalysis is isotype dependent

scientific article published in December 2015

Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain ⬇️

scientific article

Approaches to the Complete Determination of the Rotation Axes and Flexibility in the Methylene Segments of Phospholipids: Deuterium, Carbon-13, and Proton NMR Studies of Dipalmitolyl Phosphatidyl Choline

Are zinc-finger domains of protein kinase C dynamic structures that unfold by lipid or redox activation?

scientific article

Assay of the acetylcholine receptor by affinity labeling

scientific article published on 01 December 1976

Autoregulation of a bacterial sigma factor explored by using segmental isotopic labeling and NMR

scientific article

Averaging of φ2 and φ3 in [5-leucyl]-enkephalin

scientific article published on 01 October 1978

Benzyl alcohol: high levels found in plasma of uremic patients on hemodialysis

scientific article

Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms

scientific article

Binding of oxytocin and 8-arginine-vasopressin to neurophysin studied by nitrogen-15 NMR using magnetization transfer and indirect detection via protons

scientific article published on 01 October 1987

Biosynthesis and intra-axonal transport of proteins during neuronal regeneration ⬇️

scientific article published in Journal of Biological Chemistry

Branched intermediate formation stimulates peptide bond cleavage in protein splicing

scientific article

Carbon-13 NMR of the bases of three DNA oligonucleotide duplexes: assignment methods and structural features

scientific article published in 1988

Changes in 31P nuclear magnetic resonance with tumor growth in radioresistant and radiosensitive tumors

scientific article published on March 1990

Chemical ligation of folded recombinant proteins: segmental isotopic labeling of domains for NMR studies

scientific article published on January 1999

Combining biophysical methods to analyze the disulfide bond in SH2 domain of C-terminal Src kinase

scientific article published on July 2016

Conformations of side chains of somatostatin very high field proton NMR studies

Controlling lipid micelle stability using oligonucleotide headgroups

scientific article published on 3 February 2015

Correlation of chemical shifts predicted by molecular dynamics simulations for partially disordered proteins

scientific article

Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations

scientific article

Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

scientific article

Deciphering the "Fuzzy" Interaction of FG Nucleoporins and Transport Factors Using Small-Angle Neutron Scattering

scientific article published on 29 January 2018

Design of a Split Intein with Exceptional Protein Splicing Activity

scientific article

Development of highly selective SH3 binding peptides for Crk and CRKL which disrupt Crk-complexes with DOCK180, SoS and C3G.

scientific article

Direct Determination of Changes of Interdomain Orientation on Ligation: Use of the Orientational Dependence of15N NMR Relaxation in Abl SH(32)†

article

Direct Measurement of15N Chemical Shift Anisotropy in Solution

article by David Fushman et al published October 1998 in Journal of the American Chemical Society

Domain interactions of C-terminal Src Kinase determined through NMR spectroscopy with segmental isotope labeling

scientific article published on 4 November 2016

Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release

scientific article published on 20 December 2017

Effects of FGFR2 kinase activation loop dynamics on catalytic activity

scientific article

Eigenvector synchronization, graph rigidity and the molecule problem.

scientific article published on December 2012

Enhanced affinities and specificities of consolidated ligands for the Src homology (SH) 3 and SH2 domains of Abelson protein-tyrosine kinase.

scientific article

Enzymatic semisynthesis of porcine despentapeptide (B26-30) insulin using unprotected desoctapeptide (B23-30) insulin as a substrate

Erratum to: Correlation of chemical shifts predicted by molecular dynamics simulations for partially disordered proteins

article

Evidence for the cerebral uptake in vivo from two pools of glucose and the role of glucose-6-phosphatase in removing excess substrate from brain

scientific article

Expression and purification of Src-family kinases for solution NMR studies

scientific article published in January 2012

Extein residues play an intimate role in the rate-limiting step of protein trans-splicing

scientific article published on 2 April 2013

Flexibility of interdomain contacts revealed by topological isomers of bivalent consolidated ligands to the dual Src homology domain SH(32) of abelson.

scientific article

From individual proteins to whole cells

Global structures of IgG isotypes expressing identical variable regions

scientific article

Helical encounter

scientific article published on 01 August 1994

Heteronuclear two-dimensional15N- and13C-nmr studies of DNA oligomers and their netropsin complexes using indirect proton detection

scientific article published in 1991

Hydrogen--deuterium exchange kinetics of the amide protons of oxytocin studied by nuclear magnetic resonance

scientific article

INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication

scientific article published on 12 May 2021

Identification of Hydrophobic Interfaces in Protein-Ligand Complexes by Selective Saturation Transfer NMR Spectroscopy.

scientific article published on 9 December 2015

Identification of the Binding Site for Acidic Phospholipids on the PH Domain of Dynamin: Implications for Stimulation of GTPase Activity

Impact of Cl and Na ions on simulated structure and dynamics of βARK1 PH domain

scholarly article by Stefania Pfeiffer published in May 1999

Impact of Cl- and Na+ ions on simulated structure and dynamics of betaARK1 PH domain

article

In vivo monitoring of changes in 5-fluorouracil metabolism induced by methotrexate measured by 19F NMR spectroscopy

scientific article published on May 1991

In-Cell Protein NMR Spectroscopy

In-cell NMR for protein-protein interactions (STINT-NMR).

scientific article published in January 2006

Integrating NOE and RDC using sum-of-squares relaxation for protein structure determination.

scientific article

Interactions of a cobra neurotoxin and affinity labels of the acetylcholine receptor in the electroplax

scientific article published on 01 November 1972

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

scientific journal article

Joint composite-rotation adiabatic-sweep isotope filtration

scientific article published on 13 March 2007

Lectin domains in the toxin of Bordetella pertussis: selectin mimicry linked to microbial pathogenesis.

scientific article published on December 1994

Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1

scientific article

Local control of a disorder-order transition in 4E-BP1 underpins regulation of translation via eIF4E.

scientific article

Mapping structural interactions using in-cell NMR spectroscopy (STINT-NMR).

scientific article published on February 2006

Methods for the study of the conformation of small peptide hormones and antibiotics in solution

scientific article

Model-Independent Analysis of15N Chemical Shift Anisotropy from NMR Relaxation Data. Ubiquitin as a Test Example

article

Modular peptide recognition domains in eukaryotic signaling ⬇️

scientific article published on January 1, 1997

Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex.

scientific article published on 2 February 2017

Moving parts: how the adaptor protein CRK is regulated and regulates

Much more than the sum of the parts: structures of the dual SH2 domains of ZAP-70 and Syp.

scientific article published on February 1996

N-terminal cysteinyl proteins can be prepared using thrombin cleavage

scientific article published on 10 March 2008

NMR determination that an extended BH3 motif of pro-apoptotic BID is specifically bound to BCL-XL.

scientific article published in July 2006

NMR solution structure and backbone dynamics of domain III of the E protein of tick-borne Langat flavivirus suggests a potential site for molecular recognition

scientific article (publication date: June 2006)

NMR structure determination and investigation using a reduced proton (REDPRO) labeling strategy for proteins

scientific article published on 01 July 2002

Naturally split inteins assemble through a "capture and collapse" mechanism

scientific article

Novel mechanism of regulation of the non-receptor protein tyrosine kinase Csk: insights from NMR mapping studies and site-directed mutagenesis

scientific article

Novel structures of self-associating stapled peptides

scientific article published on 14 December 2011

Nuclear magnetic resonance relaxation in determination of residue-specific 15N chemical shift tensors in proteins in solution: protein dynamics, structure, and applications of transverse relaxation optimized spectroscopy.

scientific article

Nuclear spin relaxation in isotropic and anisotropic media

scientific article

Observation of arginyl-deoxyoligonucleotide interactions in Taq I endonuclease by detection of specific 1H NMR signals from 140kD [N eta 1, N eta 2, 15N Arg]Taq I/oligomer complexes.

scientific article

On the measurement of 15N-{1H} nuclear Overhauser effects

scientific article

On the measurement of ¹⁵N-{¹H} nuclear Overhauser effects. 2. Effects of the saturation scheme and water signal suppression

scientific article

Optical Activity of Biopolymers ⬇️

scientific article

Optimized bacterial expression and purification of the c-Src catalytic domain for solution NMR studies

scientific article published on 28 April 2009

Peptide chemical ligation inside living cells: in vivo generation of a circular protein domain.

scientific article

Peptide recognition by PTB and PDZ domains ⬇️

scientific article published on December 1, 1997

Peptide recognition mechanisms of eukaryotic signaling modules.

scientific article published in January 1998

Perspectives on NMR in drug discovery: a technique comes of age

scientific article

Protein backbone dynamics through 13C'-13Calpha cross-relaxation in NMR spectroscopy

scientific article published on August 2006

Proton NMR studies of vesicles incorporating glycophorin

scientific article published on 01 November 1981

Quantitative changes in tumor metabolism, partial pressure of oxygen, and radiobiological oxygenation status postradiation

scientific article published in September 1992

Radiation dose-dependent changes in tumor metabolism measured by 31P nuclear magnetic resonance spectroscopy

scientific article published on 01 September 1994

Resurfaced ZIKV EDIII nanoparticle immunogens elicit neutralizing and protective responses in vivo

scientific article published on 28 February 2022

Rotational isomerism in leucine: proton magnetic resonance study of [gamma-2H]leucine and thermodynamic analysis

scientific article published in April 1977

Secondary structure of Src homology 2 domain of c-Abl by heteronuclear NMR spectroscopy in solution

scientific article published on December 1992

Segmental Isotopic Labeling of Proteins for NMR Study Using Intein Technology

scientific article published in January 2017

Segmental isotopic labeling for structural biological applications of NMR.

scientific article

Segmental isotopic labeling of proteins for nuclear magnetic resonance

scientific article published on January 2009

Segmental isotopic labeling using expressed protein ligation

scientific article

Semisynthesis of a segmental isotopically labeled protein splicing precursor: NMR evidence for an unusual peptide bond at the N-extein-intein junction

scientific article

Side chain torsional angles and rotational isomerism of oxytocin in aqueous solution

scientific article published in August 1977

Slide-and-exchange mechanism for rapid and selective transport through the nuclear pore complex

scientific article published on 18 April 2016

Solution Structure of a Hydrocarbon Stapled Peptide Inhibitor in Complex with Monomeric C-terminal Domain of HIV-1 Capsid

scientific article

Solution Structures of FcεRI α-Chain Mimics: A β-Hairpin Peptide and Its Retroenantiomer

scientific article published in 1997

Solution structure and dynamics of the bioactive retroviral M domain from Rous sarcoma virus

scientific article

Solution structure and folding characteristics of the C-terminal SH3 domain of c-Crk-II.

scientific article

Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists

scientific article

Src homology adaptor proteins: more than the sum of the parts?

scientific article

Structural and dynamical features of inteins and implications on protein splicing

scientific article published in Journal of Biological Chemistry

Structural and dynamical features of inteins and implications on protein splicing.

scientific article

Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk

scientific article

Structural determination of biomolecular interfaces by nuclear magnetic resonance of proteins with reduced proton density

scientific article published on 7 April 2010

Suppression of artefacts in nuclear overhauser effect difference spectroscopy by reference deconvolution

Suppression of t1 Noise in 2D NMR Spectroscopy by Reference Deconvolution

Synthesis of 1-13C and 3-13C isotopic isomers of aspartic and glutamic acids

scholarly article by Upinder Fotadar & David Cowburn published August 1983 in Journal of Labelled Compounds and Radiopharmaceuticals

The Affinity-Labeling of Partially Purified Acetylcholine Receptor from Electric Tissue of Electrophorus ⬇️

scientific article published on December 1, 1973

The Effect of Finite Sampling on the Determination of Orientational Properties: A Theoretical Treatment with Application to Interatomic Vectors in Proteins

scientific article published in 2000

The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition

scientific article

The binding of ATP and AMP to Escherichia coli adenylate kinase investigated by 1H and 15N NMR spectroscopy

scientific article

The corrected nucleotide sequences of the TaqI restriction and modification enzymes reveal a thirteen-codon overlap.

scientific article published in March 1992

The effect of noncollinearity of 15N-1H dipolar and 15N CSA tensors and rotational anisotropy on 15N relaxation, CSA/dipolar cross correlation, and TROSY.

scientific article

The main-chain dynamics of the dynamin pleckstrin homology (PH) domain in solution: analysis of 15N relaxation with monomer/dimer equilibration 1 1 Edited by P.E.Wright

article

The molecular mechanism of nuclear transport revealed by atomic-scale measurements

scientific article

The origin of multiple quadrupole couplings in the deuterium NMR spectra of the 2 chain of 1,2 dipalmitoyl-sn -glycero-3-phosphorylcholine

scientific article published on 01 April 1981

The solution structure and dynamics of the pleckstrin homology domain of G protein-coupled receptor kinase 2 (beta-adrenergic receptor kinase 1). A binding partner of Gbetagamma subunits

scientific article

The solution structure of Abl SH3, and its relationship to SH2 in the SH(32) construct

scientific article

The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains

scientific article

The structure of the IgE Cepsilon2 domain and its role in stabilizing the complex with its high-affinity receptor FcepsilonRIalpha

scientific article

The virtual NMR spectrometer: a computer program for efficient simulation of NMR experiments involving pulsed field gradients

scientific article published in August 2000

Thermodynamic characterization of the multivalent interactions underlying rapid and selective translocation through the nuclear pore complex

scientific article published on 26 January 2018

Three-dimensional solution structure of the src homology 2 domain of c-abl

article

Triple resonance-based assignment for Abl SH(32) and its complex with a consolidated ligand.

scientific article

Trypsin-catalysed formation of pig des-(23-63)-proinsulin from desoctapeptide-(B23-30)-insulin

scientific article published on March 1986

Variable region identical immunoglobulins differing in isotype express different paratopes

scientific article

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