Search filters

List of works by Thomas Wisniewski

3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 1: Brain Stem

scientific article published on 31 January 2019

3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 2: Basal Forebrain

scientific article published on 13 June 2019

5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease

scientific article

A Prospective Study of Neurologic Disorders in Hospitalized COVID-19 Patients in New York City

scientific article published on 05 October 2020

A cross-species approach to disorders affecting brain and behaviour

A humanized single-chain antibody against beta 3 integrin inhibits pulmonary metastasis by preferentially fragmenting activated platelets in the tumor microenvironment.

scientific article

A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice

scientific article published on 08 February 2007

A novel human disease with abnormal prion protein sensitive to protease

scientific article

A safer vaccine for Alzheimer's disease?

scientific article

A synthetic peptide blocking the apolipoprotein E/beta-amyloid binding mitigates beta-amyloid toxicity and fibril formation in vitro and reduces beta-amyloid plaques in transgenic mice.

scientific article

ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice

scientific article published on 21 December 2018

APOE-amyloid interaction: Therapeutic targets

scientific article published on 04 February 2020

Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders

scientific article

Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro

scientific article published in November 1994

Accumulation of alpha B-crystallin in central nervous system glia and neurons in pathologic conditions

scientific article published on February 1992

Active immunotherapy for Alzheimer's disease.

scientific article published on 6 June 2012

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

scientific article published on 10 December 2015

Alpha B-crystallin is associated with intermediate filaments in astrocytoma cells

scientific article

Alzheimer Disease and Its Growing Epidemic: Risk Factors, Biomarkers, and the Urgent Need for Therapeutics

scientific article

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

scientific article

Alzheimer's beta-amyloid peptide is conformationally modified by apolipoprotein E in vitro.

scientific article published in February 1996

Alzheimer's disease: brain desmosterol levels.

scientific article published on January 2013

Alzheimer's disease: experimental models and reality

scientific article published on 26 December 2016

Alzheimer's presenilin 1 gene expression in platelets and megakaryocytes. Identification of a novel splice variant

scientific article published on September 1996

Amyloid beta 1-42 deposits do not lead to Alzheimer's neuritic plaques in aged dogs.

scientific article published on January 1996

Amyloid beta binding proteins in vitro and in normal human cerebrospinal fluid

scientific article published on 01 May 1995

Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization

scientific article published on April 2008

Amyloid beta40/42 clearance across the blood-brain barrier following intra-ventricular injections in wild-type, apoE knock-out and human apoE3 or E4 expressing transgenic mice.

scientific article published in February 2001

Amyloid β and Tau Alzheimer's disease related pathology is reduced by Toll-like receptor 9 stimulation.

scientific article

Amyloid-beta deposition is associated with decreased hippocampal glucose metabolism and spatial memory impairment in APP/PS1 mice.

scientific article

Amyloid-beta immunisation for Alzheimer's disease

scientific article published on 28 July 2008

Amyloidosis in Alzheimer's disease

scientific article published on 01 August 1995

An aggregation-specific enzyme-linked immunosorbent assay: detection of conformational differences between recombinant PrP protein dimers and PrP(Sc) aggregates

scientific article published on October 2005

An animal model of vascular amyloidosis

scientific article published on 01 September 2004

An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-beta derivatives.

scientific article published on July 2004

An entorhinal cortex sulcal pattern is associated with Alzheimer's disease

scientific article published on March 2009

Anti-PrP Mab 6D11 suppresses PrP(Sc) replication in prion infected myeloid precursor line FDC-P1/22L and in the lymphoreticular system in vivo

scientific article published on May 2009

Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an Alzheimer's disease model mouse

scientific article

Anti-prion antibodies for prophylaxis following prion exposure in mice

scientific article published on 01 January 2003

Anti-β-sheet conformation monoclonal antibody reduces tau and Aβ oligomer pathology in an Alzheimer's disease model

scientific article published on 29 January 2018

Antiviral therapy: Valacyclovir Treatment of Alzheimer's Disease (VALAD) Trial: protocol for a randomised, double-blind,placebo-controlled, treatment trial

scientific article published on 06 February 2020

Apolipoprotein Ε ε4 Frequency Is Increased among Chinese Patients with Frontotemporal Dementia and Alzheimer's Disease

scientific article published on July 23, 2013

Apolipoprotein E and amyloidogenesis

scientific article published on 01 January 1996

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

scientific article

Apolipoprotein E isoform-specific regulation of dendritic spine morphology in apolipoprotein E transgenic mice and Alzheimer's disease patients

scientific article

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

scientific article

Apolipoprotein E: binding to soluble Alzheimer's beta-amyloid

scientific article published on 01 April 1993

Apolipoprotein e: essential catalyst of the Alzheimer amyloid cascade

scientific article published on 15 July 2012

Assessment of chemokine receptor function on monocytes in whole blood: In vitro and ex vivo evaluations of a CCR2 antagonist

scientific article

Biochemical and conformational variability of human prion strains in sporadic Creutzfeldt-Jakob disease.

scientific article

Biology of Aβ Amyloid in Alzheimer's Disease

scientific article published on January 1, 1997

Blocking the apolipoprotein E/amyloid β interaction in triple transgenic mice ameliorates Alzheimer's disease related amyloid β and tau pathology

scientific article

Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta

scientific article

Brain-region-specific alterations of the trajectories of neuronal volume growth throughout the lifespan in autism

scientific article

Carbonic anhydrase inhibition selectively prevents amyloid β neurovascular mitochondrial toxicity

scientific article published on 05 June 2018

Cell type- and brain structure-specific patterns of distribution of minibrain kinase in human brain

scientific article published in June 2004

Cerebrospinal fluid inhibits Alzheimer beta-amyloid fibril formation in vitro

scientific article published in October 1993

Chemical Fluorescent Probe for Detection of Aβ Oligomers

scientific article published on 28 July 2015

Circulating amyloid-beta peptide crosses the blood-brain barrier in aged monkeys and contributes to Alzheimer's disease lesions

scientific article published in June 2002

Class C CpG Oligodeoxynucleotide Immunomodulatory Response in Aged Squirrel Monkey (Saimiri Boliviensis Boliviensis)

scientific article published on 03 March 2020

Clearance and prevention of prion infection in cell culture by anti-PrP antibodies.

scientific article published in May 2006

Clearance systems in the brain--implications for Alzheimer diseaser

scientific article

Clearance systems in the brain-implications for Alzheimer disease

scientific article

Comparative analysis of cognitive impairment prevalence and its etiological subtypes in a rural area of northern China between 2010 and 2015

scientific article published in Scientific Reports

Conformation as therapeutic target in the prionoses and other neurodegenerative conditions

scientific article

Contribution of olivofloccular circuitry developmental defects to atypical gaze in autism

scientific article published on 02 April 2013

Copper chelation delays the onset of prion disease

scientific article published on 30 September 2003

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature

scientific article published on May 2012

Could immunomodulation be used to prevent prion diseases?

scientific article published on March 1, 2012

CpG oligodeoxynucleotide-enhanced humoral immune response and production of antibodies to prion protein PrPSc in mice immunized with 139A scrapie-associated fibrils

scientific article published on 22 March 2007

Decreases in plasma A beta 1-40 levels with aging in non-demented elderly with ApoE-epsilon 4 allele

article

Deficit of corpus callosum axons, reduced axon diameter and decreased area are markers of abnormal development of interhemispheric connections in autistic subjects

scientific article published on 19 December 2018

Detection of Alzheimer's amyloid in transgenic mice using magnetic resonance microimaging

scientific article published in August 2003

Detection of amyloid plaques targeted by USPIO-Aβ1-42 in Alzheimer's disease transgenic mice using magnetic resonance microimaging

scientific article published on 19 January 2011

Detection of amyloid plaques targeted by bifunctional USPIO in Alzheimer's disease transgenic mice using magnetic resonance microimaging

scientific article

Detection of apolipoprotein E/dimeric soluble amyloid beta complexes in Alzheimer's disease brain supernatants

scientific article

Developing therapeutic vaccines against Alzheimer's disease

scientific article

Diaryl substituted pyrazoles as potent CCR2 receptor antagonists

scientific article published on 25 October 2006

Differences between the pattern of developmental abnormalities in autism associated with duplications 15q11.2-q13 and idiopathic autism

scientific article published on May 2012

Disease modifying approaches for Alzheimer's pathology.

scientific article published on January 2007

Dissolution of arterial platelet thrombi in vivo with a bifunctional platelet GPIIIa49-66 ligand which specifically targets the platelet thrombus

scientific article

Dissolution of pre-existing platelet thrombus by synergistic administration of low concentrations of bifunctional antibodies against β3 integrin

scientific article

Early onset Alzheimer's disease in a South American pedigree from Argentina

scientific article published in January 1995

Enrichment of presenilin 1 peptides in neuronal large dense-core and somatodendritic clathrin-coated vesicles

scientific article published in December 1998

Epitope map of two polyclonal antibodies that recognize amyloid lesions in patients with Alzheimer's disease

scientific article published on March 1992

Epitope scanning reveals gain and loss of strain specific antibody binding epitopes associated with the conversion of normal cellular prion to scrapie prion.

scientific article

Evidence for cyclic diguanylate as a vaccine adjuvant with novel immunostimulatory activities

scientific article published in July 2012

FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer's disease

scientific article published on 14 January 2009

Familial Alzheimer's disease connected with mutation in presenilin gene 1 (P117L)

scientific article

Familial cerebral amyloid angiopathy (British type) with nonneuritic amyloid plaque formation may be due to a novel amyloid protein

scientific article published on 01 March 1995

Familial meningocerebrovascular amyloidosis, Hungarian type, with mutant transthyretin (TTR Asp18Gly)

scientific article published in December 1996

Fibrillar amyloid-beta affects neurofibrillary changes but only in neurons already involved in neurofibrillary degeneration

scientific article published in June 2001

Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E.

scientific article published on March 1995

Follow-up of active Aβ immunization in Alzheimer disease

scientific article published on 01 September 2019

Future horizons in Alzheimer's disease research

scientific article published on 22 August 2019

GATA1-mediated transcriptional regulation of the γ-secretase activating protein increases Aβ formation in Down syndrome

scientific article published on 08 October 2015

Gelsolin immunoreactivity in corneal amyloid, wound healing, and macular and granular dystrophies

scientific article published on 01 May 1993

Gelsolin variant and beta-amyloid co-occur in a case of Alzheimer's with Lewy bodies

scientific article published in July 1991

Generation and Partial Characterization of Rabbit Monoclonal Antibody to Pyroglutamate Amyloid-β3-42 (pE3-Aβ).

scientific article published on 22 August 2018

Greater specificity for cerebrospinal fluid P-tau231 over P-tau181 in the differentiation of healthy controls from Alzheimer's disease

scientific article

HB-GAM is a cytokine present in Alzheimer's and Down's syndrome lesions.

scientific article published in January 1996

Henry M. Wisniewski M.D. Ph.D.

scientific article published on 01 February 2001

High titers of mucosal and systemic anti-PrP antibodies abrogate oral prion infection in mucosal-vaccinated mice.

scientific article published on 6 March 2008

Human Umbilical Cord Stem Cell Xenografts Improve Cognitive Decline and Reduce the Amyloid Burden in a Mouse Model of Alzheimer's Disease

scientific article published on 4 October 2016

Immunization delays the onset of prion disease in mice.

scientific article published on July 2002

Immunization treatment approaches in Alzheimer's and prion diseases.

scientific article

Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice

scientific article published on August 2001

Immunomodulation for prion and prion-related diseases

scientific article published on December 1, 2010

Immunomodulation targeting abnormal protein conformation reduces pathology in a mouse model of Alzheimer's disease

scientific article

Immunomodulation targeting of both Aβ and tau pathological conformers ameliorates Alzheimer's disease pathology in TgSwDI and 3xTg mouse models

scientific article published on 13 December 2013

Immunotherapeutic approaches for Alzheimer's disease

scientific article

Immunotherapeutic approaches for Alzheimer's disease in transgenic mouse models.

scientific article published on 10 December 2009

Immunotherapy for Alzheimer's disease

scientific article published on 09 January 2014

Immunotherapy to improve cognition and reduce pathological species in an Alzheimer's disease mouse model.

scientific article

In vivo magnetic resonance imaging of amyloid-β plaques in mice

scientific article published on January 2012

In vivo micro magnetic resonance imaging signal changes in scrapie infected mice

scientific article

In vivo reversal of amyloid-beta lesions in rat brain

scientific article published in January 2000

Induction of toll-like receptor 9 signaling as a method for ameliorating Alzheimer's disease-related pathology

scientific article

Infectivity of amyloid diseases

scientific article published on 01 September 2002

Influence of Mabs on PrPSc Formation Using In Vitro and Cell-Free Systems

scientific article published on July 27, 2012

Inherited amyloids of the nervous system

scientific article published on October 1, 1991

Innate Immunity Stimulation via Toll-Like Receptor 9 Ameliorates Vascular Amyloid Pathology in Tg-SwDI Mice with Associated Cognitive Benefits

scientific article published on January 2017

Inner SPACE: 400-Micron Isotropic Resolution MRI of the Human Brain

scientific article published on 19 March 2020

Intraneuronal Abeta immunoreactivity is not a predictor of brain amyloidosis-beta or neurofibrillary degeneration

scientific article published on 20 January 2007

Intraneuronal Abeta42 accumulation in Down syndrome brain

scientific article published in June 2002

Is Alzheimer's disease an apolipoprotein E amyloidosis?

scientific article published in April 1995

Is multiple system atrophy an infectious disease?

scientific article published on 2 January 2018

Is vaccination against transmissible spongiform encephalopathy feasible?

scientific article published on April 2007

Isolation of Amyloid Plaques and Neurofibrillary Tangles from Archived Alzheimer's Disease Tissue Using Laser-Capture Microdissection for Downstream Proteomics

scientific article published in January 2018

LATE to the PART-y

scientific article published on 01 September 2019

Lewy bodies are immunoreactive with antibodies raised to gelsolin related amyloid-Finnish type

scientific article published on May 1, 1991

Light and electron microscopic immunolocalization of presenilin 1 in abnormal muscle fibers of patients with sporadic inclusion-body myositis and autosomal-recessive inclusion-body myopathy

scientific article published on April 1998

Link between DYRK1A overexpression and several-fold enhancement of neurofibrillary degeneration with 3-repeat tau protein in Down syndrome

scientific article

Localization of alpha-tocopherol transfer protein in the brains of patients with ataxia with vitamin E deficiency and other oxidative stress related neurodegenerative disorders

scientific article

Longitudinal cerebrospinal fluid tau load increases in mild cognitive impairment

scientific article published in November 2002

Lower CSF amyloid beta peptides and higher F2-isoprostanes in cognitively intact elderly individuals with major depressive disorder

scientific article published on May 2012

MRI assessment of neuropathology in a transgenic mouse model of Alzheimer's disease.

scientific article published in April 2004

Magnetic resonance imaging of amyloid plaques in transgenic mice

scientific article published in January 2005

Mapping the antigenicity of copper-treated cellular prion protein with the scrapie isoform.

scientific article

Mechanistic insights into the cure of prion disease by novel antiprion compounds

scientific article

Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid Abeta peptide

scientific article published in December 2001

Memantine leads to behavioral improvement and amyloid reduction in Alzheimer's-disease-model transgenic mice shown as by micromagnetic resonance imaging

scientific article published in September 2008

Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein

scientific article

Micropreparative gel electrophoresis of low-molecular-weight peptides: purification of highly insoluble amyloid peptide fragments

scientific article published in May 1996

Molecular biology of Alzheimer's amyloid--Dutch variant

scientific article published on January 1, 1992

Molecular biology of brain aging and neurodegenerative disorders.

scientific article published on January 1996

Molecular targeting of Alzheimer's amyloid plaques for contrast-enhanced magnetic resonance imaging

scientific article

Mucosal immunization with an attenuated Salmonella vaccine partially protects white-tailed deer from chronic wasting disease

scientific article published on 21 December 2014

Mucosal vaccination delays or prevents prion infection via an oral route.

scientific article

Multiregional Age-Associated Reduction of Brain Neuronal Reserve Without Association With Neurofibrillary Degeneration or β-Amyloidosis

scientific article published on 13 May 2017

Murine models of Alzheimer's disease and their use in developing immunotherapies.

scientific article published on 13 May 2010

Nerve growth factor metabolic dysfunction in Down's syndrome brains.

scientific article published on 11 February 2014

Neuronal nucleus and cytoplasm volume deficit in children with autism and volume increase in adolescents and adults.

scientific article

Notch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: Implications for cellular Aβ metabolism

scientific article published on October 19, 2011

Novel Mouse Tauopathy Model for Repetitive Mild Traumatic Brain Injury: Evaluation of Long-Term Effects on Cognition and Biomarker Levels After Therapeutic Inhibition of Tau Phosphorylation

scientific article published on 11 March 2019

Novel immunological approaches for the treatment of Alzheimer's disease

scientific article

On the biological activity of vitamin E

scientific article published on 01 July 2000

Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice

scientific article

PART, a distinct tauopathy, different from classical sporadic Alzheimer disease

scientific article

Partial Agenesis and Hypoplasia of the Corpus Callosum in Idiopathic Autism

scientific article published in March 2017

Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation

scientific article published in November 1991

Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation

scientific article published in September 1991

Perturbed mitochondria-ER contacts in live neurons that model the amyloid pathology of Alzheimer's disease

scientific article published on 22 October 2019

Phosphorylated tau interactome in the human Alzheimer's disease brain

scientific article published on 19 August 2020

Pituitary hemorrhage into a Rathke's cleft cyst

scientific article published on 01 October 1990

Plaque-associated overexpression of insulin-degrading enzyme in the cerebral cortex of aged transgenic tg2576 mice with Alzheimer pathology

scientific article published in October 2006

Potential Novel Approaches to Understand the Pathogenesis and Treat Alzheimer's Disease

scientific article published on 16 March 2018

Potential role of apolipoprotein-E in fibrillogenesis

scientific article published on September 1994

Presenilin-1 is associated with Alzheimer's disease amyloid

scientific article published on August 1, 1997

Prevalence of cognitive impairment no dementia in a rural area of Northern China

scientific article

Prevalence of dementia and main subtypes in rural northern China

scientific article published on 14 March 2015

Preventing beta-amyloid fibrillization and deposition: beta-sheet breakers and pathological chaperone inhibitors

scientific article

Primary age-related tauopathy (PART): a common pathology associated with human aging

scientific article

Prion diseases and the immune system

scientific article published on 01 February 1999

Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice

scientific article published in May 2004

Production of Monoclonal Antibodies to Pathologic β-sheet Oligomeric Conformers in Neurodegenerative Diseases

scientific article

Prominent neuroleptic sensitivity in a case of early-onset Alzheimer disease due to presenilin-1 G206A mutation

scientific article published on September 2008

Promising developments in prion immunotherapy

scientific article published on 01 October 2005

Proteomic analysis of neurons microdissected from formalin-fixed, paraffin-embedded Alzheimer's disease brain tissue

scientific article published on 21 October 2015

Proteomic differences in amyloid plaques in rapidly progressive and sporadic Alzheimer's disease

scientific article

Proteomic differences in the hippocampus and cortex of epilepsy brain tissue

scientific article published on 09 March 2021

Psychometric Cognitive Decline Precedes the Advent of Subjective Cognitive Decline in the Evolution of Alzheimer's Disease

scientific article published on 08 May 2020

Recent advancements toward therapeutic vaccines against Alzheimer’s disease

scientific article published on 09 August 2018

Reversion of prion protein conformational changes by synthetic b-sheet breaker peptides

scientific article published in The Lancet

Rhesus monkey model for concurrent analyses of in vivo selectivity, pharmacokinetics and pharmacodynamics of aldosterone synthase inhibitors

scientific article published on 07 October 2014

Role of CD40 in prion disease and the immune response to recombinant PrP

scientific article published on 16 February 2013

S182 protein in Alzheimer's disease neuritic plaques

scientific article published in November 1995

Secernin-1 is a novel phosphorylated tau binding protein that accumulates in Alzheimer's disease and not in other tauopathies

scientific article published on 03 December 2019

Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation.

scientific article published in February 1996

Significant neuronal soma volume deficit in the limbic system in subjects with 15q11.2-q13 duplications

scientific article

State-dependent alterations in cerebrospinal fluid Aβ42 levels in cognitively intact elderly with late-life major depression

scientific article published on 9 August 2016

Stereological study of the neuronal number and volume of 38 brain subdivisions of subjects diagnosed with autism reveals significant alterations restricted to the striatum, amygdala and cerebellum

scientific article

Styryl-based and tricyclic compounds as potential anti-prion agents

scientific article (publication date: 2011)

Styryl-based compounds as potential in vivo imaging agents for beta-amyloid plaques

scientific article published in September 2007

Synthesis and immunological activities of novel Toll-like receptor 7 and 8 agonists.

scientific article published on 22 April 2011

Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides, aluminum hydroxide and its soluble salts

scientific article

TGF-β Blockade Reduces Mortality and Metabolic Changes in a Validated Murine Model of Pancreatic Cancer Cachexia

scientific article published on 14 July 2015

Targeting Apolipoprotein E/Amyloid β Binding by Peptoid CPO_Aβ17-21 P Ameliorates Alzheimer's Disease Related Pathology and Cognitive Decline.

scientific article published on 14 August 2017

Targeting prion amyloid deposits in vivo.

scientific article

Tau phosphorylation induced by severe closed head traumatic brain injury is linked to the cellular prion protein

scientific article

Tau-based therapeutic approaches for Alzheimer's disease - a mini-review.

scientific article published on 08 April 2014

Test for detection of disease-associated prion aggregate in the blood of infected but asymptomatic animals

scientific article published on November 2006

The Cox-2 Inhibitor Meloxicam Ameliorates Neuroinflammation and Depressive Behavior in Adult Mice after Splenectomy

scientific article published on 5 August 2016

The Role of TREM2 in Alzheimer's Disease and Other Neurological Disorders.

scientific article

The amino acid sequence of neuritic plaque amyloid from a familial Alzheimer's disease patient

scientific article published in February 1994

The amyloid plaque proteome in early onset Alzheimer's disease and Down syndrome

scientific article published on 13 April 2022

The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex

scientific article published on July 1993

The dominant form of the pigmentary orthochromatic leukodystrophy

scientific article published on January 1, 1991

The innate immune system in Alzheimer's disease.

scientific article published on 02 October 2013

The interaction between apolipoprotein E and Alzheimer's amyloid beta-peptide is dependent on beta-peptide conformation

scientific article published on 01 May 1996

The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes

scientific article

The prionoses and other conformational disorders

scientific article published in September 1998

The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome

scientific article published on 12 August 2008

The role of reduced expression of fragile X mental retardation protein in neurons and increased expression in astrocytes in idiopathic and syndromic autism (duplications 15q11.2-q13)

scientific article published on 14 August 2018

The use of localized proteomics to identify the drivers of Alzheimer's disease pathogenesis

scientific article published on June 2017

Therapeutic effects of astrocytes expressing both tyrosine hydroxylase and brain-derived neurotrophic factor on a rat model of Parkinson's disease

scientific article published in January 2002

Therapeutics and prion disease: can immunisation or drugs be effective?

scientific article

Thymoma-associated panencephalitis: a newly emerging paraneoplastic neurologic syndrome.

scientific article published on 16 June 2017

Transthyretin gene in Alzheimer's disease patients

scientific article published in February 1996

Two Year Outcomes, Cognitive and Behavioral Markers of Decline in Healthy, Cognitively Normal Older Persons with Global Deterioration Scale Stage 2 (Subjective Cognitive Decline with Impairment)

scientific article published on 01 January 2019

Using Proteomics to Understand Alzheimer’s Disease Pathogenesis

Vaccination as a therapeutic approach to Alzheimer's disease.

scientific article published on January 2010

Vaccination of Alzheimer's model mice with Abeta derivative in alum adjuvant reduces Abeta burden without microhemorrhages

scientific article published on November 2006

Vaccination strategies

scientific article published on 01 January 2018

Vascular fibrosis and calcification in the hippocampus in aging, Alzheimer disease, and Down syndrome.

scientific article published on 28 November 2001