List of works - Hon Wai Lam

A second-generation ligand for the enantioselective rhodium-catalyzed addition of arylboronic acids to alkenylazaarenes

article

All-Carbon [3+3] Oxidative Annulations of 1,3-Enynes by Rhodium(III)-Catalyzed C-H Functionalization and 1,4-Migration

scientific article published on 15 July 2015

Aromatic Heterocycles as Activating Groups for Asymmetric Conjugate Addition Reactions. Enantioselective Copper-Catalyzed Reduction of 2-Alkenylheteroarenes

article

Arylative Intramolecular Allylation of Ketones with 1,3-Enynes Enabled by Catalytic Alkenyl-to-Allyl 1,4-Rhodium(I) Migration

scientific article published on 19 May 2017

Base-catalyzed synthesis of bicyclic 4-aminopyrimidines from the reaction of dinitriles with mononitriles

Catalyst-controlled divergent C-H functionalization of unsymmetrical 2-aryl cyclic 1,3-dicarbonyl compounds with alkynes and alkenes

scientific article published on 15 July 2013

Catalytic 1,4-rhodium(III) migration enables 1,3-enynes to function as one-carbon oxidative annulation partners in C-H functionalizations

scientific article published on 22 July 2014

Catalytic asymmetric dihydroxylation of enamides and application to the total synthesis of (+)-tanikolide

scientific article published on November 2010

Cobalt-catalyzed reductive Mannich reactions of 4-acryloylmorpholine with N-tosyl aldimines

scientific article published on 19 November 2007

Copper-Bisphosphine-Initiated Pentafluorophenylation of Aldehydes and Ketones

Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines.

scientific article published in March 2016

Copper-catalyzed silylation of cyclopropenes using (trifluoromethyl)trimethylsilane

scientific article

Cu(I)-catalyzed reductive aldol cyclizations: diastereo- and enantioselective synthesis of beta-hydroxylactones

scientific article published in September 2005

C═N-containing azaarenes as activating groups in enantioselective catalysis

scientific article published in February 2014

Diastereo- and Enantioselective Pd(II)-Catalyzed Additions of 2-Alkylazaarenes to N-Boc Imines and Nitroalkenes

article

Diastereoselective Cobalt-Catalyzed Alkylative Aldol Cyclizations Using Trialkylaluminum Reagents

scientific article published on 13 June 2008

Diastereoselective Cobalt-Catalyzed Reductive Aldol Cyclizations Using Diethylzinc as the Stoichiometric Reductant

scientific article published on 01 August 2006

Diastereoselective Intermolecular Cobalt-Catalyzed Reductive Aldol Reactions of α,β-Unsaturated Amides with Ketones

scientific article published on 15 September 2007

Diastereoselective Synthesis of 4-Hydroxypiperidin-2-ones via Cu(I)-Catalyzed Reductive Aldol Cyclization†

scientific article published on 01 December 2005

Diastereoselective nickel-catalyzed reductive aldol cyclizations using diethylzinc as the stoichiometric reductant: scope and mechanistic insight

scientific article published on 16 May 2008

Direct Synthesis of 5-Aryl Barbituric Acids by Rhodium(II)-Catalyzed Reactions of Arenes with Diazo Compounds

scientific article published on 8 May 2015

Enantioselective Copper(I)-Catalyzed Borylative Aldol Cyclizations of Enone Diones

scientific article published on 28 September 2012

Enantioselective Copper-Catalyzed Reductive Coupling of Alkenylazaarenes with Ketones

scientific article published on 11 May 2012

Enantioselective Copper-Catalyzed Reductive Coupling of Vinylazaarenes with N-Boc Aldimines

Enantioselective Copper-Catalyzed Reductive Michael Cyclizations

scientific article published on 01 October 2009

Enantioselective Nickel-Catalyzed Intramolecular Allylic Alkenylations Enabled by Reversible Alkenylnickel E/Z Isomerization

scientific article published on 24 May 2017

Enantioselective Nickel-Catalyzed Michael Additions of 2-Acetylazaarenes to Nitroalkenes

article

Enantioselective Nickel-Catalyzed Michael Additions of Azaarylacetates and Acetamides to Nitroalkenes

article

Enantioselective Nickel-Catalyzed anti-Carbometallative Cyclizations of Alkynyl Electrophiles Enabled by Reversible Alkenylnickel E/Z Isomerization

scientific article published on 22 June 2016

Enantioselective Rh(I)-catalyzed cyclization of arylboron compounds onto ketones.

scientific article

Enantioselective Rhodium-Catalyzed Addition of Arylboronic Acids to Alkenylheteroarenes

article

Enantioselective Rhodium-Catalyzed Addition of Potassium Alkenyltrifluoroborates to Cyclic Imines

article

Enantioselective Rhodium-Catalyzed Allylation of Cyclic Imines with Potassium Allyltrifluoroborates

scholarly article by Hon Wai Lam et al published 31 July 2013 in Synthesis

Enantioselective Rhodium-Catalyzed Coupling of Arylboronic Acids, 1,3-Enynes, and Imines by Alkenyl-to-Allyl 1,4-Rhodium(I) Migration

scientific article

Enantioselective Rhodium‐Catalyzed Nucleophilic Allylation of Cyclic Imines with Allylboron Reagents ⬇️

scientific article published on July 11, 2012

Enantioselective Synthesis of Allylboronates and Allylic Alcohols by Copper-Catalyzed 1,6-Boration

scientific article published on 12 March 2014

Enantioselective Synthesis of Chiral Cyclopent-2-enones by Nickel-Catalyzed Desymmetrization of Malonate Esters.

scientific article published on 19 June 2018

Enantioselective Synthesis of Spiroindenes by Enol-Directed Rhodium(III)-Catalyzed C-H Functionalization and Spiroannulation.

scientific article published on 25 September 2015

Enantioselective nickel-catalyzed arylative intramolecular 1,4-allylations

scientific article published on 01 May 2018

Enantioselective rhodium-catalyzed arylation of electron-deficient alkenylarenes

Enantioselective synthesis of bicyclo[3.n.1]alkanes by chiral phosphoric acid-catalyzed desymmetrizing Michael cyclizations.

scientific article

Formal synthesis of salinosporamide A using a nickel-catalyzed reductive aldol cyclization–lactonization as a key step

scholarly article by Isabel Villanueva Margalef et al published August 2008 in Tetrahedron

Functionalization of C sp 3H and C sp 2H Bonds: Synthesis of Spiroindenes by Enolate-Directed Ruthenium-Catalyzed Oxidative Annulation of Alkynes with 2-Aryl-1,3-dicarbonyl Compounds

scientific article published on 24 October 2012

Heteroatom methods

Iridium-catalyzed 1,5-(aryl)aminomethylation of 1,3-enynes by alkenyl-to-allyl 1,4-iridium(i) migration

scientific article published on 01 January 2019

Iridium-catalyzed arylative cyclization of alkynones by 1,4-iridium migration

scientific article published on 19 May 2014

Nickel-catalyzed, ligand-free, diastereoselective synthesis of 3-methyleneindan-1-ols

article

One-Carbon Oxidative Annulations of 1,3-Enynes by Catalytic C-H Functionalization and 1,4-Rhodium(III) Migration.

scientific article published on 21 February 2018

Palladium-catalyzed hydroacyloxylation of ynamides

article

Preparation of multisubstituted enamides via rhodium-catalyzed carbozincation and hydrozincation of ynamides

scientific article published in October 2009

Racemic and asymmetric cobalt-catalysed reductive aldol couplings of α,β-unsaturated amides with ketones

scholarly article by Ralph J.R. Lumby et al published August 2008 in Tetrahedron

Remote Nucleophilic Allylation by Allylrhodium Chain Walking

scientific article published on 20 August 2018

Rhodium-Catalyzed Annulation of Ynamides with Bifunctional Arylboron Reagents

scientific article published on 01 June 2010

Rhodium-Catalyzed Oxidative C-H Allylation of Benzamides with 1,3-Dienes by Allyl-to-Allyl 1,4-Rh(III) Migration.

scientific article published on 6 September 2016

Rhodium-Catalyzed [2 + 2] Cycloaddition of Ynamides with Nitroalkenes

article

Rhodium-catalyzed carbometalation of ynamides with organoboron reagents

scholarly article by Benoit Gourdet et al published August 2010 in Tetrahedron

Stereoselective Formation of Alkenyl Halides via Magnesium Halide Promoted Ring Opening of Bis-Activated Cyclopropenes

scientific article published on 01 February 2009

Stereoselective synthesis of multisubstituted enamides via rhodium-catalyzed carbozincation of ynamides

scientific article published in March 2009

Stereoselective synthesis of tri- and tetrasubstituted alkenes by iron-catalyzed carbometalation ring-opening reactions of cyclopropenes

scientific article published in January 2008

Sulfonylative and Azidosulfonylative Cyclizations by Visible-Light-Photosensitization of Sulfonyl Azides in THF.

scientific article

Switchable Synthesis of Z-Homoallylic Boronates and E-Allylic Boronates by Enantioselective Copper-Catalyzed 1,6-Boration

scientific article published on 15 May 2018

Synthesis and Application of Alkenylstannanes Derived from Base-Sensitive Cyclopropenes

scientific article published on 23 August 2008

Synthesis of Benzopyrans by Pd(II)- or Ru(II)-Catalyzed C–H Alkenylation of 2-Aryl-3-hydroxy-2-cyclohexenones

scientific article published on 14 January 2013

Synthesis of Pyroglutamic Acid Derivatives via Double Michael Reactions of Alkynones

scientific article published on 25 April 2007

Synthesis of Spirocyclic Enones by Rhodium-Catalyzed Dearomatizing Oxidative Annulation of 2-Alkenylphenols with Alkynes and Enynes

scientific article published on 06 June 2014

Synthesis of multisubstituted pyrroles by nickel-catalyzed arylative cyclizations of N-tosyl alkynamides

article

Synthesis of spiroindanes by palladium-catalyzed oxidative annulation of non- or weakly activated 1,3-dienes involving C–H functionalization

scientific article published on 01 February 2015

TADDOL-Derived Phosphonites, Phosphites, and Phosphoramidites in Asymmetric Catalysis

The isomerization of allylrhodium intermediates in the rhodium-catalyzed nucleophilic allylation of cyclic imines

scientific article published on 9 September 2014

Total synthesis of the presumed amphidinolide A

scientific article published on 01 February 2002

Ytterbium-Catalyzed Conjugate Allylation of Alkylidene Malonates

scientific article published on 27 April 2011

List of works by Hon Wai Lam

A second-generation ligand for the enantioselective rhodium-catalyzed addition of arylboronic acids to alkenylazaarenes

All-Carbon [3+3] Oxidative Annulations of 1,3-Enynes by Rhodium(III)-Catalyzed C-H Functionalization and 1,4-Migration

Aromatic Heterocycles as Activating Groups for Asymmetric Conjugate Addition Reactions. Enantioselective Copper-Catalyzed Reduction of 2-Alkenylheteroarenes

Arylative Intramolecular Allylation of Ketones with 1,3-Enynes Enabled by Catalytic Alkenyl-to-Allyl 1,4-Rhodium(I) Migration

Base-catalyzed synthesis of bicyclic 4-aminopyrimidines from the reaction of dinitriles with mononitriles

Catalyst-controlled divergent C-H functionalization of unsymmetrical 2-aryl cyclic 1,3-dicarbonyl compounds with alkynes and alkenes

Catalytic 1,4-rhodium(III) migration enables 1,3-enynes to function as one-carbon oxidative annulation partners in C-H functionalizations

Catalytic asymmetric dihydroxylation of enamides and application to the total synthesis of (+)-tanikolide

Cobalt-catalyzed reductive Mannich reactions of 4-acryloylmorpholine with N-tosyl aldimines

Copper-Bisphosphine-Initiated Pentafluorophenylation of Aldehydes and Ketones

Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines.

Copper-catalyzed silylation of cyclopropenes using (trifluoromethyl)trimethylsilane

Cu(I)-catalyzed reductive aldol cyclizations: diastereo- and enantioselective synthesis of beta-hydroxylactones

C═N-containing azaarenes as activating groups in enantioselective catalysis

Diastereo- and Enantioselective Pd(II)-Catalyzed Additions of 2-Alkylazaarenes to N-Boc Imines and Nitroalkenes

Diastereoselective Cobalt-Catalyzed Alkylative Aldol Cyclizations Using Trialkylaluminum Reagents

Diastereoselective Cobalt-Catalyzed Reductive Aldol Cyclizations Using Diethylzinc as the Stoichiometric Reductant

Diastereoselective Intermolecular Cobalt-Catalyzed Reductive Aldol Reactions of α,β-Unsaturated Amides with Ketones

Diastereoselective Synthesis of 4-Hydroxypiperidin-2-ones via Cu(I)-Catalyzed Reductive Aldol Cyclization†

Diastereoselective nickel-catalyzed reductive aldol cyclizations using diethylzinc as the stoichiometric reductant: scope and mechanistic insight

Direct Synthesis of 5-Aryl Barbituric Acids by Rhodium(II)-Catalyzed Reactions of Arenes with Diazo Compounds

Enantioselective Copper(I)-Catalyzed Borylative Aldol Cyclizations of Enone Diones

Enantioselective Copper-Catalyzed Reductive Coupling of Alkenylazaarenes with Ketones

Enantioselective Copper-Catalyzed Reductive Coupling of Vinylazaarenes with N-Boc Aldimines

Enantioselective Copper-Catalyzed Reductive Michael Cyclizations

Enantioselective Nickel-Catalyzed Intramolecular Allylic Alkenylations Enabled by Reversible Alkenylnickel E/Z Isomerization

Enantioselective Nickel-Catalyzed Michael Additions of 2-Acetylazaarenes to Nitroalkenes

Enantioselective Nickel-Catalyzed Michael Additions of Azaarylacetates and Acetamides to Nitroalkenes

Enantioselective Nickel-Catalyzed anti-Carbometallative Cyclizations of Alkynyl Electrophiles Enabled by Reversible Alkenylnickel E/Z Isomerization

Enantioselective Rh(I)-catalyzed cyclization of arylboron compounds onto ketones.

Enantioselective Rhodium-Catalyzed Addition of Arylboronic Acids to Alkenylheteroarenes

Enantioselective Rhodium-Catalyzed Addition of Potassium Alkenyltrifluoroborates to Cyclic Imines

Enantioselective Rhodium-Catalyzed Allylation of Cyclic Imines with Potassium Allyltrifluoroborates

Enantioselective Rhodium-Catalyzed Coupling of Arylboronic Acids, 1,3-Enynes, and Imines by Alkenyl-to-Allyl 1,4-Rhodium(I) Migration

Enantioselective Rhodium‐Catalyzed Nucleophilic Allylation of Cyclic Imines with Allylboron Reagents ⬇️

Enantioselective Synthesis of Allylboronates and Allylic Alcohols by Copper-Catalyzed 1,6-Boration

Enantioselective Synthesis of Chiral Cyclopent-2-enones by Nickel-Catalyzed Desymmetrization of Malonate Esters.

Enantioselective Synthesis of Spiroindenes by Enol-Directed Rhodium(III)-Catalyzed C-H Functionalization and Spiroannulation.

Enantioselective nickel-catalyzed arylative intramolecular 1,4-allylations

Enantioselective rhodium-catalyzed arylation of electron-deficient alkenylarenes

Enantioselective synthesis of bicyclo[3.n.1]alkanes by chiral phosphoric acid-catalyzed desymmetrizing Michael cyclizations.

Formal synthesis of salinosporamide A using a nickel-catalyzed reductive aldol cyclization–lactonization as a key step

Functionalization of C sp 3H and C sp 2H Bonds: Synthesis of Spiroindenes by Enolate-Directed Ruthenium-Catalyzed Oxidative Annulation of Alkynes with 2-Aryl-1,3-dicarbonyl Compounds

Heteroatom methods

Iridium-catalyzed 1,5-(aryl)aminomethylation of 1,3-enynes by alkenyl-to-allyl 1,4-iridium(i) migration

Iridium-catalyzed arylative cyclization of alkynones by 1,4-iridium migration

Nickel-catalyzed, ligand-free, diastereoselective synthesis of 3-methyleneindan-1-ols

One-Carbon Oxidative Annulations of 1,3-Enynes by Catalytic C-H Functionalization and 1,4-Rhodium(III) Migration.

Palladium-catalyzed hydroacyloxylation of ynamides

Preparation of multisubstituted enamides via rhodium-catalyzed carbozincation and hydrozincation of ynamides

Racemic and asymmetric cobalt-catalysed reductive aldol couplings of α,β-unsaturated amides with ketones

Remote Nucleophilic Allylation by Allylrhodium Chain Walking

Rhodium-Catalyzed Annulation of Ynamides with Bifunctional Arylboron Reagents

Rhodium-Catalyzed Oxidative C-H Allylation of Benzamides with 1,3-Dienes by Allyl-to-Allyl 1,4-Rh(III) Migration.

Rhodium-Catalyzed [2 + 2] Cycloaddition of Ynamides with Nitroalkenes

Rhodium-catalyzed carbometalation of ynamides with organoboron reagents

Stereoselective Formation of Alkenyl Halides via Magnesium Halide Promoted Ring Opening of Bis-Activated Cyclopropenes

Stereoselective synthesis of multisubstituted enamides via rhodium-catalyzed carbozincation of ynamides

Stereoselective synthesis of tri- and tetrasubstituted alkenes by iron-catalyzed carbometalation ring-opening reactions of cyclopropenes

Sulfonylative and Azidosulfonylative Cyclizations by Visible-Light-Photosensitization of Sulfonyl Azides in THF.

Switchable Synthesis of Z-Homoallylic Boronates and E-Allylic Boronates by Enantioselective Copper-Catalyzed 1,6-Boration

Synthesis and Application of Alkenylstannanes Derived from Base-Sensitive Cyclopropenes

Synthesis of Benzopyrans by Pd(II)- or Ru(II)-Catalyzed C–H Alkenylation of 2-Aryl-3-hydroxy-2-cyclohexenones

Synthesis of Pyroglutamic Acid Derivatives via Double Michael Reactions of Alkynones

Synthesis of Spirocyclic Enones by Rhodium-Catalyzed Dearomatizing Oxidative Annulation of 2-Alkenylphenols with Alkynes and Enynes

Synthesis of multisubstituted pyrroles by nickel-catalyzed arylative cyclizations of N-tosyl alkynamides

Synthesis of spiroindanes by palladium-catalyzed oxidative annulation of non- or weakly activated 1,3-dienes involving C–H functionalization

TADDOL-Derived Phosphonites, Phosphites, and Phosphoramidites in Asymmetric Catalysis

The isomerization of allylrhodium intermediates in the rhodium-catalyzed nucleophilic allylation of cyclic imines

Total synthesis of the presumed amphidinolide A

Ytterbium-Catalyzed Conjugate Allylation of Alkylidene Malonates