List of works - Georg Karpel-Massler

A Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy

scientific article published on 29 June 2015

A Synthetic Cell-Penetrating Dominant-Negative ATF5 Peptide Exerts Anticancer Activity against a Broad Spectrum of Treatment-Resistant Cancers

scientific article

A critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapy

scientific article

A paired comparison between glioblastoma "stem cells" and differentiated cells

scientific article published on 30 October 2015

Anti-glioma Activity of Dapsone and Its Enhancement by Synthetic Chemical Modification

scientific article published on 29 August 2017

Artesunate enhances the antiproliferative effect of temozolomide on U87MG and A172 glioblastoma cell lines

scientific article published on February 2014

Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis

scientific article

CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide

scientific article

Cell Death Induction in Cancer Therapy - Past, Present, and Future

scientific article published on January 2016

Combined inhibition of Bcl-2/Bcl-xL and Usp9X/Bag3 overcomes apoptotic resistance in glioblastoma in vitro and in vivo

scientific article

Combined inhibition of HER1/EGFR and RAC1 results in a synergistic antiproliferative effect on established and primary cultured human glioblastoma cells

scientific article published on 5 July 2013

Drug combinations enhancing the antineoplastic effects of erlotinib in high-grade glioma

scientific article published on September 2011

Epidermal to Mesenchymal Transition and Failure of EGFR-Targeted Therapy in Glioblastoma

scientific article published on 08 May 2012

Erlotinib in glioblastoma: lost in translation?

scientific article published on October 2011

GDC-0941 enhances the lysosomal compartment via TFEB and primes glioblastoma cells to lysosomal membrane permeabilization and cell death

scientific article

Glioblastoma-synthesized G-CSF and GM-CSF contribute to growth and immunosuppression: Potential therapeutic benefit from dapsone, fenofibrate, and ribavirin

scientific article published on May 2017

Inhibition of NF-κB signaling ablates the invasive phenotype of glioblastoma

scientific article published on 21 October 2013

Inhibition of deubiquitinases primes glioblastoma cells to apoptosis in vitro and in vivo

scientific article published on 10 February 2016

Killing me softly--future challenges in apoptosis research

scientific article

Metabolic reprogramming of glioblastoma cells by L-asparaginase sensitizes for apoptosis in vitro and in vivo

scientific article published on 09 May 2016

Molecular, histopathological, and genomic variants of glioblastoma

scientific article published on June 2014

Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect

scientific article published on 19 December 2014

PARP inhibition restores extrinsic apoptotic sensitivity in glioblastoma

scientific article published on 22 December 2014

Phosphoinositide 3-kinases upregulate system xc(-) via eukaryotic initiation factor 2α and activating transcription factor 4 - A pathway active in glioblastomas and epilepsy

scientific article

RIST: a potent new combination therapy for glioblastoma

scientific article published on September 2014

Regression/eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide

scientific article published on 05 February 2016

TIC10/ONC201 synergizes with Bcl-2/Bcl-xL inhibition in glioblastoma by suppression of Mcl-1 and its binding partners in vitro and in vivo

scientific article published on 12 October 2015

Targeting intrinsic apoptosis and other forms of cell death by BH3-mimetics in glioblastoma

scientific article published on 17 July 2017

The rationale of targeting neutrophils with dapsone during glioblastoma treatment

scientific article published on October 2011

Therapeutic inhibition of the epidermal growth factor receptor in high-grade gliomas: where do we stand?

scientific article published on 07 July 2009

Toward a noncytotoxic glioblastoma therapy: blocking MCP-1 with the MTZ Regimen

scientific article

List of works by Georg Karpel-Massler

A Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy

A Synthetic Cell-Penetrating Dominant-Negative ATF5 Peptide Exerts Anticancer Activity against a Broad Spectrum of Treatment-Resistant Cancers

A critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapy

A paired comparison between glioblastoma "stem cells" and differentiated cells

Anti-glioma Activity of Dapsone and Its Enhancement by Synthetic Chemical Modification

Artesunate enhances the antiproliferative effect of temozolomide on U87MG and A172 glioblastoma cell lines

Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis

CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide

Cell Death Induction in Cancer Therapy - Past, Present, and Future

Combined inhibition of Bcl-2/Bcl-xL and Usp9X/Bag3 overcomes apoptotic resistance in glioblastoma in vitro and in vivo

Combined inhibition of HER1/EGFR and RAC1 results in a synergistic antiproliferative effect on established and primary cultured human glioblastoma cells

Drug combinations enhancing the antineoplastic effects of erlotinib in high-grade glioma

Epidermal to Mesenchymal Transition and Failure of EGFR-Targeted Therapy in Glioblastoma

Erlotinib in glioblastoma: lost in translation?

GDC-0941 enhances the lysosomal compartment via TFEB and primes glioblastoma cells to lysosomal membrane permeabilization and cell death

Glioblastoma-synthesized G-CSF and GM-CSF contribute to growth and immunosuppression: Potential therapeutic benefit from dapsone, fenofibrate, and ribavirin

Inhibition of NF-κB signaling ablates the invasive phenotype of glioblastoma

Inhibition of deubiquitinases primes glioblastoma cells to apoptosis in vitro and in vivo

Killing me softly--future challenges in apoptosis research

Metabolic reprogramming of glioblastoma cells by L-asparaginase sensitizes for apoptosis in vitro and in vivo

Molecular, histopathological, and genomic variants of glioblastoma

Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect

PARP inhibition restores extrinsic apoptotic sensitivity in glioblastoma

Phosphoinositide 3-kinases upregulate system xc(-) via eukaryotic initiation factor 2α and activating transcription factor 4 - A pathway active in glioblastomas and epilepsy

RIST: a potent new combination therapy for glioblastoma

Regression/eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide

TIC10/ONC201 synergizes with Bcl-2/Bcl-xL inhibition in glioblastoma by suppression of Mcl-1 and its binding partners in vitro and in vivo

Targeting intrinsic apoptosis and other forms of cell death by BH3-mimetics in glioblastoma

The rationale of targeting neutrophils with dapsone during glioblastoma treatment

Therapeutic inhibition of the epidermal growth factor receptor in high-grade gliomas: where do we stand?

Toward a noncytotoxic glioblastoma therapy: blocking MCP-1 with the MTZ Regimen