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List of works by Paul G. Winyard

7,8-Dihydro-8-oxo-2'-deoxyguanosine present in DNA is not simply an artefact of isolation

scientific article published in February 1994

A Modified Form of Low-Density Lipoprotein with Increased Electronegative Charge is Present in Rheumatoid Arthritis Synovial Fluid

scientific article published on 01 January 1997

A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells.

scientific article published on 16 March 2018

A mechanism of release of calreticulin from cells during apoptosis

scientific article

A novel hybrid promoter responsive to pathophysiological and pharmacological regulation

scientific article

A panel of oxidative stress assays does not provide supplementary diagnostic information in Behcet's disease patients

scientific article

A possible role for ferritin during inflammation

scientific article published on January 1985

A reappraisal of xanthine dehydrogenase and oxidase in hypoxic reperfusion injury: the role of NADH as an electron donor

scientific article published on 01 February 1998

Action of free radical generating systems upon the biological and immunological properties of caeruloplasmin

scientific article published on 01 January 1984

Activation of the transcription factor NF-kappaB in the rat air pouch model of inflammation

scientific article published in April 2000

Activation of the transcription factor nuclear factor-κB in human inflamed synovial tissue

scientific article published on 01 April 1996

Acute L-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance

scientific article published on 19 August 2010

Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise

article

Acute dietary nitrate supplementation improves cycling time trial performance

scientific article published on 01 June 2011

Advances in understanding the genetic basis of rheumatoid arthritis and osteoarthritis: implications for therapy.

scientific article

Ageing modifies the effects of beetroot juice supplementation on 24-hour blood pressure variability: An individual participant meta-analysis.

scientific article published on 29 April 2015

Alpha-tocopherol, lipids and lipoproteins in knee-joint synovial fluid and serum from patients with inflammatory joint disease

scientific article published on 01 December 1992

Amelioration of antigen-induced arthritis in rats by transfer of extracellular superoxide dismutase and catalase genes

scientific article published in April 2003

An automated method for the kinetic measurement of ferroxidase activity

scientific article published in May 1988

An imaginative approach to synovitis--the role of hypoxic reperfusion damage in arthritis

scientific article

Analysis of nitrite and nitrate in the study of inflammation

scientific article

Analysis of radicals and radical reaction products in cell signalling and biomolecular damage: the long hard road to gold-standard measures

scientific article published on October 2011

Antioxidants, redox-regulated transcription factors, and inflammation

scientific article published on January 1997

Ascorbate promotes low density lipoprotein oxidation in the presence of ferritin

scientific article published on 01 December 1996

Aspects of the biological redox chemistry of cysteine: from simple redox responses to sophisticated signalling pathways.

scientific article published on October 2006

Autoantibodies to posttranslational modifications in rheumatoid arthritis ⬇️

scientific article published on 23 March 2014

Autoantibodies to posttranslationally modified type II collagen as potential biomarkers for rheumatoid arthritis

scientific article published in July 2013

Beetroot juice and exercise: pharmacodynamic and dose-response relationships.

scientific article published on 2 May 2013

Biomarkers of early stage osteoarthritis, rheumatoid arthritis and musculoskeletal health

scientific article

Bleomycin-induced unscheduled DNA synthesis in non-permeabilized human and rat hepatocytes is not paralleled by 8-oxo-7,8-dihydrodeoxyguanosine formation

scientific article published on 01 October 1992

COPPER CHELATION AND THE NEURO-OPHTHALMIC TOXICITY OF DESFERRIOXAMINE

scientific article published in The Lancet

Cerebral and ocular toxicity induced by desferrioxamine

scientific article published on July 1985

Changes in Apoptotic Gene Expression in Lymphocytes from Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients Compared with Healthy Lymphocytes

article

Changes in inflammatory gene expression induced by hyperbaric oxygen treatment in human endothelial cells under chronic wound conditions.

scientific article

Characterization of the radical product formed from the reaction of nitric oxide with the spin trap 3,5-dibromo-4-nitrosobenzene sulfonate

scientific article published in April 2001

Clinical Relevance of Biomarkers of Oxidative Stress

scientific article

Copper-induced LDL peroxidation investigated by 1H-NMR spectroscopy

article

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

scientific article published on 26 October 2017

Cysteine-cystine redox cycling in a gold-gold dual-plate generator-collector microtrench sensor

scientific article published on 23 June 2014

Detection and isolation of human serum autoantibodies that recognize oxidatively modified autoantigens

scientific article published on 12 December 2012

Detection and measurement of reactive oxygen intermediates in mitochondria and cells

scientific article

Detection of hydrogen sulfide in plasma and knee-joint synovial fluid from rheumatoid arthritis patients: relation to clinical and laboratory measures of inflammation

scientific article published on 01 August 2010

Detection of oxidants in uremic plasma by electron spin resonance spectroscopy

scientific article published on 01 July 1995

Determination of S-nitrosothiols in biological and clinical samples using electron paramagnetic resonance spectrometry with spin trapping

scientific article published on January 2008

Determining the site of spin trapping of the equine myoglobin radical by combined use of EPR, electrophoretic purification, and mass spectrometry

scientific article

Dietary nitrate accelerates postexercise muscle metabolic recovery and O2 delivery in hypoxia

scientific article

Dietary nitrate modulates cerebral blood flow parameters and cognitive performance in humans: A double-blind, placebo-controlled, crossover investigation

scientific article published on 31 May 2015

Dietary nitrate reduces muscle metabolic perturbation and improves exercise tolerance in hypoxia

article by Anni Vanhatalo et al published 12 September 2011 in Journal of Physiology

Dietary nitrate supplementation improves reaction time in type 2 diabetes: Development and application of a novel nitrate-depleted beetroot juice placebo

article

Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans

article by Stephen J. Bailey et al published October 2009 in Journal of Applied Physiology

Dietary nitrate supplementation reduces the O2 cost of walking and running: a placebo-controlled study

scientific article published on 11 November 2010

Dietary nitrate supplementation: effects on plasma nitrite and pulmonary O2 uptake dynamics during exercise in hypoxia and normoxia

scientific article published on 09 July 2014

Dietary nitrate--good or bad?

scientific article published on 27 October 2009

Different oxygen treatment pressures alter inflammatory gene expression in human endothelial cells

scientific article

Effect of dietary nitrate on blood pressure, endothelial function, and insulin sensitivity in type 2 diabetes.

scientific article published on 8 February 2013

Effect of nitrate supplementation on hepatic blood flow and glucose homeostasis: a double-blind, placebo-controlled, randomized control trial

scientific article published on 14 July 2016

Effects of dietary nitrate supplementation on the oxygen cost of exercise and walking performance in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled crossover trial

article

Effects of oxidative stress on some physiochemical properties of caeruloplasmin

scientific article published on March 1989

Effects of short-term dietary nitrate supplementation on blood pressure, O2 uptake kinetics, and muscle and cognitive function in older adults.

scientific article published on 21 November 2012

Endothelial cell cytotoxicity in inflammatory vascular diseases--the possible role of oxidised lipoproteins

scientific article

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

scientific article published on 18 May 2017

Evidence for oxidised low density lipoprotein in synovial fluid from rheumatoid arthritis patients

scientific article published on 01 June 2000

Extent of oxidative modification of low density lipoprotein determines the degree of cytotoxicity to human coronary artery cells

scientific article published on January 1996

Extracellular calreticulin is present in the joints of patients with rheumatoid arthritis and inhibits FasL (CD95L)-mediated apoptosis of T cells

scientific article

Formation and role of plasma S-nitrosothiols in liver ischemia-reperfusion injury

scientific article

Free radicals in inflammation: second messengers and mediators of tissue destruction.

scientific article

Generation of Nitric Oxide by a Nitrite Reductase Activity of Xanthine Oxidase: A Potential Pathway for Nitric Oxide Formation in the Absence of Nitric Oxide Synthase Activity

scientific article published on 01 August 1998

Generation of neoantigenic epitopes after posttranslational modification of type II collagen by factors present within the inflamed joint

scientific article published in December 2005

Human single-chain variable fragment that specifically targets arthritic cartilage

scientific article

Human xanthine oxidase converts nitrite ions into nitric oxide (NO)

scientific article published on 01 August 1997

Hydrogen peroxide and tumour necrosis factor-alpha induce NF-kappaB-DNA binding in primary human T lymphocytes in addition to T cell lines

scientific article published in December 2001

Hydrogen sulfide and nitric oxide interactions in inflammation

scientific article

Hyperbaric oxygen treatment induces platelet aggregation and protein release, without altering expression of activation molecules.

scientific article published on 8 January 2009

Hyperbaric oxygen treatment reduces neutrophil-endothelial adhesion in chronic wound conditions through S-nitrosation.

scientific article

Impact of theophylline/corticosteroid combination therapy on sputum hydrogen sulfide levels in patients with COPD

scientific article published on 13 February 2014

Inactivation of antithrombin III in synovial fluid from patients with rheumatoid arthritis ⬇️

scientific article published on March 1, 1998

Inactivation of synovial fluid α1 -antitrypsin by exercise of the inflamed rheumatoid joint

scientific article published on 01 April 1993

Inactivation of the elastase inhibitory activity of alpha 1 antitrypsin in fresh samples of synovial fluid from patients with rheumatoid arthritis

scientific article

Inactivation of tissue inhibitor of metalloproteinase-1 by peroxynitrite

scientific article published on 01 February 1996

Increased proteolytic cleavage of alpha 1-antitrypsin (alpha 1-proteinase inhibitor) in knee-joint synovial fluid from patients with rheumatoid arthritis.

scientific article published in October 1990

Inducible hydrogen sulfide synthesis in chondrocytes and mesenchymal progenitor cells: is H2S a novel cytoprotective mediator in the inflamed joint?

scientific article published on April 2012

Influence of N-acetylcysteine administration on pulmonary O2 uptake kinetics and exercise tolerance in humans

scientific article published on 16 October 2010

Influence of dietary nitrate supplementation on human skeletal muscle metabolism and force production during maximum voluntary contractions

scientific article published on 26 January 2013

Influence of iodide ingestion on nitrate metabolism and blood pressure following short-term dietary nitrate supplementation in healthy normotensive adults

scientific article published on 23 December 2016

Inhibition of neutrophil superoxide production by human plasma α1 -antitrypsin

article

LIPID PEROXIDATION AND PARKINSON'S DISEASE

scientific article published in The Lancet

Lipoprotein oxidation and induction of ferroxidase activity in stored human extracellular fluids

scientific article published on 01 January 1989

Lymphocytes from rheumatoid arthritis patients have elevated levels of intracellular peroxiredoxin 2, and a greater frequency of cells with exofacial peroxiredoxin 2, compared with healthy human lymphocytes ⬇️

scientific article published on April 28, 2012

MECHANISM OF EXACERBATION OF RHEUMATOID SYNOVITIS BY TOTAL-DOSE IRON-DEXTRAN INFUSION: IN-VIVO DEMONSTRATION OF IRON-PROMOTED OXIDANT STRESS

scientific article published in The Lancet

Measurement and meaning of markers of reactive species of oxygen, nitrogen and sulfur in healthy human subjects and patients with inflammatory joint disease.

scientific article published on October 2011

Measurement of S-nitrosothiols in extracellular fluids from healthy human volunteers and rheumatoid arthritis patients, using electron paramagnetic resonance spectrometry

scientific article

Measurement of both native and inactivated forms of alpha1 proteinase inhibitor in human inflammatory extracellular fluids

scientific article published in September 2003

Mechanisms of α1-Antitrypsin Inactivation in Arthritic Joints: Comment on the Article by Abbink et a1

scientific article published on 01 January 1994

Modified low density lipoprotein and cytokines mediate monocyte adhesion to smooth muscle cells.

scientific article

Movement disorder associated with abnormal copper metabolism and decreased blood antioxidants

scientific article published on September 1987

Myeloperoxidase and oxidative stress in rheumatoid arthritis

scientific article published on 19 July 2012

NF-kappa B activation in human knee-joint synovial tissue during the early stage of joint inflammation

scientific article published on 01 August 1997

Network analysis of nitrate-sensitive oral microbiome reveals interactions with cognitive function and cardiovascular health across dietary interventions

scientific article published on 05 March 2021

Nitrate pharmacokinetics: Taking note of the difference

scientific article published on 29 April 2015

Nitric oxide and the regulation of apoptosis in tumour cells.

scientific article published on January 2006

Nitrite determination in human plasma and synovial fluid using reactions of nitric oxide with 3,5-dibromo-4-nitrosobenzenesulphonate (DBNBS)

article

Nitrite/nitrate detection in serum based on dual-plate generator-collector currents in a microtrench.

scientific article published on 5 August 2014

Non-caeruloplasmin-bound copper ('phenanthroline copper') is not detectable in fresh serum or synovial fluid from patients with rheumatoid arthritis

scientific article published on October 1987

Nuclear transcription factors: potential targets for new modes of intervention in skin disease.

scientific article published on November 1994

Ocular toxicity of desferrioxamine--an example of copper promoted auto-oxidative damage?

scientific article

On the mechanism by which dietary nitrate improves human skeletal muscle function

scientific article (publication date: 2015)

Optimisation of an Advanced Oxidation Protein Products Assay: Its Application to Studies of Oxidative Stress in Diabetes Mellitus

scientific article published on 14 May 2015

Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases

scientific article

Oxidative Stress in Rheumatoid Arthritis

article

Oxidative activation of antioxidant defence

scientific article

Oxidative and other posttranslational modifications in extracellular vesicle biology

scientific article published on 24 February 2015

Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases.

scientific article

Oxidative stress and its control: a pathogenetic role in inflammatory joint disease

scientific article

Peroxiredoxin V in multiple sclerosis lesions: predominant expression by astrocytes

scientific article (publication date: September 2007)

Plasma S-nitrosothiol status in neonatal calves: ontogenetic associations with tissue-specific S-nitrosylation and nitric oxide synthase

scientific article published on 01 February 2007

Presence of foam cells containing oxidised low density lipoprotein in the synovial membrane from patients with rheumatoid arthritis

scientific article published on September 1993

Proteolysis of human native and oxidised α1-proteinase inhibitor by matrulysin and stromelysin

scientific article published on 01 March 1994

Proteolytic inactivation of human α1 antitrypsin by human stromelysin

scientific article published on 01 February 1991

Proton NMR studies of a tetrasaccharide which is a receptor for uropathogenic E. coli bacteria.

scientific article published in January 1982

Purity of different preparations of sodium 3,5-dibromo-4-nitrosobenzenesulphonate and their applicability for EPR spin trapping

scientific article published in January 2003

Putative analgesic activity of repeated oral doses of vitamin E in the treatment of rheumatoid arthritis. Results of a prospective placebo controlled double blind trial ⬇️

scientific article published on November 1, 1997

Reaction of the spin trap 3,5-dibromo-4-nitrosobenzene sulfonate with human biofluids

scientific article published in August 2002

Redox Signaling and Regulation in Biology and Medicine

Relationship Between Urinary Nitrate Excretion and Blood Pressure in the InChianti Cohort.

scientific article published on 19 April 2017

Relationship between α1-antitrypsin inactivation and tumor necrosis factor α concentration in the synovial fluid of patients with rheumatoid arthritis

scientific article published on 01 December 1994

Reply to Lundberg, Larsen, and Weitzberg

Role of inorganic nitrate and nitrite in driving nitric oxide-cGMP-mediated inhibition of platelet aggregation in vitro and in vivo

scientific article published in October 2014

Role of oxidative modification in the lability of ceruloplasmin

scientific article published on 01 January 1988

Selective antimicrobial activity associated with sulfur nanoparticles.

scientific article published in June 2011

Simultaneous analysis of nitrite, nitrate and the nicotinamide nucleotides by capillary electrophoresis: application to biochemical studies and human extracellular fluids

scientific article published on July 1999

The Effects of Chronic Nitrate Supplementation and the Use of Strong and Weak Antibacterial Agents on Plasma Nitrite Concentration and Exercise Blood Pressure.

scientific article published on 2 September 2015

The behaviour of caeruloplasmin in stored human extracellular fluids in relation to ferroxidase II activity, lipid peroxidation and phenanthroline-detectable copper

scientific article published on September 1985

The complex effects of the slow-releasing hydrogen sulfide donor GYY4137 in a model of acute joint inflammation and in human cartilage cells.

scientific article published on 28 January 2013

The contribution of hypoxia-reperfusion injury to inflammatory synovitis: the influence of reactive oxygen intermediates on the transcriptional control of inflammation.

scientific article published on June 1994

The effect of dietary nitrate supplementation on the oxygen cost of cycling, walking performance and resting blood pressure in individuals with chronic obstructive pulmonary disease: A double blind placebo controlled, randomised control trial.

scientific article published on 13 January 2015

The effect of substance P on nitric oxide release in a rheumatoid arthritis model

article

The natural organosulfur compound dipropyltetrasulfide prevents HOCl-induced systemic sclerosis in the mouse

scientific article published on 28 October 2013

Thrombin in inflammation and healing: relevance to rheumatoid arthritis.

scientific article published on January 1994

Thrombin receptor expression in rheumatoid and osteoarthritic synovial tissue

scientific article published on November 1996

Two weeks of watermelon juice supplementation improves nitric oxide bioavailability but not endurance exercise performance in humans.

scientific article published in July 2016

Xanthine oxidase: four roles for the enzyme in rheumatoid pathology.

scientific article published on August 1997

l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans

scientific article published on 28 May 2015

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