List of works - Chiara Mondello

A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds

scientific article

A comprehensive strategy for the analysis of acoustic compressibility and optical deformability on single cells.

scientific article

An integrated fluorescence activated cell sorter fabricated by femtosecond laser micromachining

An integrated optofluidic device for single-cell sorting driven by mechanical properties

scientific article

An optofluidic constriction chip for monitoring metastatic potential and drug response of cancer cells

scientific article published in April 2015

Aphidicolin does not inhibit the repair synthesis of mitotic chromosomes

scientific article published on 01 April 1981

Apoptosis: a way to maintain healthy individuals

scientific article published on January 2010

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: focus on the cancer hallmark of tumor angiogenesis

scientific article

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

scientific article

Causes of genome instability: the effect of low dose chemical exposures in modern society

scientific article

Cells with stemness features are generated from in vitro transformed human fibroblasts

scientific article published in Scientific Reports

Cellular and genetic studies in three UV-sensitive Chinese hamster mutants.

scientific article published in October 1987

Cellular immortalization and neoplastic transformation: Simultaneous, sequential or independent? Telomeres, telomerase or karyotypic variations?

scientific article published on 08 May 2013

Cellular response to glutamine and/or glucose deprivation in in vitro transformed human fibroblasts

scientific article published on 17 April 2019

Chemical compounds from anthropogenic environment and immune evasion mechanisms: potential interactions

scientific article

Chromosomal Instability and Telomere Length Variations during the Life Span of Human Fibroblast Clones

scientific article published on 01 November 1997

Chromosomal effects of methotrexate on cultured human lymphocytes

scientific article published on 01 February 1984

Chromosomal end-to-end fusions in immortalized mouse embryonic fibroblasts deficient in the DNA-dependent protein kinase catalytic subunit

scientific article published on January 2004

Condensation anomalies and exclusion in micronuclei of rearranged chromosomes in human fibroblasts cultured in vitro

scientific article published on 01 November 1995

Contribution of telomerase RNA retrotranscription to DNA double-strand break repair during mammalian genome evolution

scientific article published on January 2007

Cross-analysis of gene and miRNA genome-wide expression profiles in human fibroblasts at different stages of transformation

scientific article published on January 2012

Disruptive chemicals, senescence and immortality

scientific article

Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death

scientific article

Drug treatment of cancer cell lines: a way to select for cancer stem cells?

scientific article published on 04 March 2011

Enhanced gene amplification in human cells knocked down for DNA-PKcs

scientific article published on 21 October 2008

Environmental immune disruptors, inflammation and cancer risk

scientific article

Gamma-ray and hydrogen peroxide induction of gene amplification in hamster cells deficient in DNA double strand break repair

scientific article published on June 2002

Gene amplification in Chinese hamster DNA repair deficient mutants.

scientific article published on February 1995

Gene amplification in human cells knocked down for RAD54

scientific article published on 18 March 2011

Gene amplification, radiation sensitivity and DNA double-strand breaks

scientific article published on 20 January 2010

Inhibition of gene amplification in telomerase deficient immortalized mouse embryonic fibroblasts.

scientific article published on 14 September 2006

Insertion of telomeric repeats at intrachromosomal break sites during primate evolution

scientific article published on 12 August 2004

Instability of interstitial telomeric sequences in the human genome

scientific article published in September 2000

Interstitial telomeric repeats are not preferentially involved in radiation-induced chromosome aberrations in human cells.

scientific article published on January 2004

Karyotype instability and anchorage-independent growth in telomerase-immortalized fibroblasts from two centenarian individuals

scientific article published in September 2003

Late onset of CAD gene amplification in unamplified PALA resistant Chinese hamster mutants

article

Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.

scientific article

Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?

scientific article

Methylation and expression of a housekeeping gene

article

Molecular analysis of the XP-D gene in Italian families with patients affected by trichothiodystrophy and xeroderma pigmentosum group D

article

Molecular organization of internal telomeric sequences in Chinese hamster chromosomes

scientific article published on January 2002

Multiple DNA-protein interactions at the CpG island of the human pseudoautosomal geneMIC2

article

New mammalian cellular systems to study mutations introduced at the break site by non-homologous end-joining

scientific article

Occurrence and expansion of trisomy 7 in a fibroblast strain from a centenarian individual.

scientific article published on August 1999

Optofluidic integrated cell sorter fabricated by femtosecond lasers

scientific article

Oxidative stress response in telomerase-immortalized fibroblasts from a centenarian

scientific article

Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells

scientific article

Relocalization of cell adhesion molecules during neoplastic transformation of human fibroblasts ⬇️

scientific article published on July 8, 2011

Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair

scholarly article

Sensitivity to DNA-damaging agents and mutation induction by UV light in UV-sensitive CHO cells

scientific article published on 01 June 1986

Snail levels control the migration mechanism of mesenchymal tumor cells.

scientific article published on 30 May 2016

Sorting on the basis of deformability of single cells in a femtosecond laser fabricated optofluidic device

Stable cellular senescence is associated with persistent DDR activation

scientific article

Stepwise neoplastic transformation of a telomerase immortalized fibroblast cell line

scientific article published on December 2005

Structural instability of a transmissible end-to-end dicentric chromosome in a xeroderma pigmentosum fibroblast clone

scientific article published on 01 January 1995

Super-telomeres in transformed human fibroblasts

scientific article published on 6 April 2013

Telomerase: cellular immortalization and neoplastic transformation. Multiple functions of a multifaceted complex.

scientific article published on January 2008

Telomere Length in Fibroblasts and Blood Cells from Healthy Centenarians

scientific article published on 01 April 1999

Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria ⬇️

scientific article published on September 28, 2012

Telomeres

Telomeres, telomerase, and apoptosis.

scientific article published in August 2004

The catalytic and the RNA subunits of human telomerase are required to immortalize equid primary fibroblasts

scientific article

The effect of environmental chemicals on the tumor microenvironment

scientific article

The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis

scientific article

The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling

scientific article

Transfer of a human chromosomal vector from a hamster cell line to a mouse embryonic stem cell line.

scientific article

X-linked ichthyosis, due to steroid sulphatase deficiency, associated with Kallmann syndrome (hypogonadotropic hypogonadism and anosmia): linkage relationships with Xg and cloned DNA sequences from the distal short arm of the X chromosome

scientific article published on 01 March 1986

List of works by Chiara Mondello

A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds

A comprehensive strategy for the analysis of acoustic compressibility and optical deformability on single cells.

An integrated fluorescence activated cell sorter fabricated by femtosecond laser micromachining

An integrated optofluidic device for single-cell sorting driven by mechanical properties

An optofluidic constriction chip for monitoring metastatic potential and drug response of cancer cells

Aphidicolin does not inhibit the repair synthesis of mitotic chromosomes

Apoptosis: a way to maintain healthy individuals

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: focus on the cancer hallmark of tumor angiogenesis

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

Causes of genome instability: the effect of low dose chemical exposures in modern society

Cells with stemness features are generated from in vitro transformed human fibroblasts

Cellular and genetic studies in three UV-sensitive Chinese hamster mutants.

Cellular immortalization and neoplastic transformation: Simultaneous, sequential or independent? Telomeres, telomerase or karyotypic variations?

Cellular response to glutamine and/or glucose deprivation in in vitro transformed human fibroblasts

Chemical compounds from anthropogenic environment and immune evasion mechanisms: potential interactions

Chromosomal Instability and Telomere Length Variations during the Life Span of Human Fibroblast Clones

Chromosomal effects of methotrexate on cultured human lymphocytes

Chromosomal end-to-end fusions in immortalized mouse embryonic fibroblasts deficient in the DNA-dependent protein kinase catalytic subunit

Condensation anomalies and exclusion in micronuclei of rearranged chromosomes in human fibroblasts cultured in vitro

Condensation anomalies and exclusion in micronuclei of rearranged chromosomes in human fibroblasts cultured in vitro

Contribution of telomerase RNA retrotranscription to DNA double-strand break repair during mammalian genome evolution

Cross-analysis of gene and miRNA genome-wide expression profiles in human fibroblasts at different stages of transformation

Disruptive chemicals, senescence and immortality

Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death

Drug treatment of cancer cell lines: a way to select for cancer stem cells?

Enhanced gene amplification in human cells knocked down for DNA-PKcs

Environmental immune disruptors, inflammation and cancer risk

Gamma-ray and hydrogen peroxide induction of gene amplification in hamster cells deficient in DNA double strand break repair

Gene amplification in Chinese hamster DNA repair deficient mutants.

Gene amplification in human cells knocked down for RAD54

Gene amplification, radiation sensitivity and DNA double-strand breaks

Inhibition of gene amplification in telomerase deficient immortalized mouse embryonic fibroblasts.

Insertion of telomeric repeats at intrachromosomal break sites during primate evolution

Instability of interstitial telomeric sequences in the human genome

Interstitial telomeric repeats are not preferentially involved in radiation-induced chromosome aberrations in human cells.

Karyotype instability and anchorage-independent growth in telomerase-immortalized fibroblasts from two centenarian individuals

Late onset of CAD gene amplification in unamplified PALA resistant Chinese hamster mutants

Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.

Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?

Methylation and expression of a housekeeping gene

Molecular analysis of the XP-D gene in Italian families with patients affected by trichothiodystrophy and xeroderma pigmentosum group D

Molecular organization of internal telomeric sequences in Chinese hamster chromosomes

Multiple DNA-protein interactions at the CpG island of the human pseudoautosomal geneMIC2

New mammalian cellular systems to study mutations introduced at the break site by non-homologous end-joining

Occurrence and expansion of trisomy 7 in a fibroblast strain from a centenarian individual.

Optofluidic integrated cell sorter fabricated by femtosecond lasers

Oxidative stress response in telomerase-immortalized fibroblasts from a centenarian

Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells

Relocalization of cell adhesion molecules during neoplastic transformation of human fibroblasts ⬇️

Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair

Sensitivity to DNA-damaging agents and mutation induction by UV light in UV-sensitive CHO cells

Snail levels control the migration mechanism of mesenchymal tumor cells.

Sorting on the basis of deformability of single cells in a femtosecond laser fabricated optofluidic device

Stable cellular senescence is associated with persistent DDR activation

Stepwise neoplastic transformation of a telomerase immortalized fibroblast cell line

Structural instability of a transmissible end-to-end dicentric chromosome in a xeroderma pigmentosum fibroblast clone

Super-telomeres in transformed human fibroblasts

Telomerase: cellular immortalization and neoplastic transformation. Multiple functions of a multifaceted complex.

Telomere Length in Fibroblasts and Blood Cells from Healthy Centenarians

Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria ⬇️

Telomeres

Telomeres, telomerase, and apoptosis.

The catalytic and the RNA subunits of human telomerase are required to immortalize equid primary fibroblasts

The effect of environmental chemicals on the tumor microenvironment

The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis

The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling

Transfer of a human chromosomal vector from a hamster cell line to a mouse embryonic stem cell line.

X-linked ichthyosis, due to steroid sulphatase deficiency, associated with Kallmann syndrome (hypogonadotropic hypogonadism and anosmia): linkage relationships with Xg and cloned DNA sequences from the distal short arm of the X chromosome