Search filters

List of works by Shahid M Khan

A Plasmodium phospholipase is involved in disruption of the liver stage parasitophorous vacuole membrane

scientific article

A double-blind, placebo-controlled phase 1/2a trial of the genetically attenuated malaria vaccine PfSPZ-GA1

scientific article published on 01 May 2020

A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites

scientific article

A genotype and phenotype database of genetically modified malaria-parasites

scientific article

A novel 'gene insertion/marker out' (GIMO) method for transgene expression and gene complementation in rodent malaria parasites

scientific article

A sporozoite-based vaccination platform against human malaria

scientific article published on 24 August 2018

Adenovirus-prime and baculovirus-boost heterologous immunization achieves sterile protection against malaria sporozoite challenge in a murine model.

scientific article published in March 2018

Aminoindoles, a novel scaffold with potent activity against Plasmodium falciparum

scientific article

An in vitro assay to measure antibody-mediated inhibition of P. berghei sporozoite invasion against P. falciparum antigens.

scientific article published on 5 December 2017

Assessing the adequacy of attenuation of genetically modified malaria parasite vaccine candidates

scientific article published on 16 February 2012

Assessment of the Plasmodium falciparum Preerythrocytic Antigen UIS3 as a Potential Candidate for a Malaria Vaccine

scientific article published on 28 December 2016

CCR4-associated factor 1 coordinates the expression of Plasmodium falciparum egress and invasion proteins ⬇️

scientific article

CD8+ T Cells Induce Fatal Brainstem Pathology during Cerebral Malaria via Luminal Antigen-Specific Engagement of Brain Vasculature

scientific article

Chimeric Plasmodium falciparum parasites expressing Plasmodium vivax circumsporozoite protein fail to produce salivary gland sporozoites

scientific article published on 09 August 2018

Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection

scientific article published on 8 March 2018

Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates

scientific article published on 3 July 2015

Correction: Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole

scientific article published on 17 January 2017

Correction: Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole

scientific article published on 14 December 2016

Costs of crowding for the transmission of malaria parasites

scientific article published on 11 February 2013

Deletion of the rodent malaria ortholog for falcipain-1 highlights differences between hepatic and blood stage merozoites.

scientific article published on 18 September 2017

Development of a Plasmodium vivax malaria vaccine for clinical applications using transgenic parasites, virus-like particles and recombinant viruses

scientific article published on 22 September 2014

Development of an in vitro Plasmodium parasite killing assay for the evaluation of cell-mediated immune responses following vaccination with pre-erythrocytic malaria vaccine candidates

scientific article published on 22 September 2014

Development of novel vaccine candidates and challenge models for Plasmodium vivax

scientific article published on 22 September 2014

Development of the piggyBac transposable system for Plasmodium berghei and its application for random mutagenesis in malaria parasites

scientific article

Developmental transition of Plasmodium sporozoites into liver-stage forms is regulated by the RNA binding protein Pumilio 2.

scientific article

Distribution and characterisation of the 235 kDa rhoptry multigene family within the genomes of virulent and avirulent lines of Plasmodium yoelii

scientific article published in May 2001

Efficacy and safety of artemehter-lumefantrine in uncomplicated falciparum malaria in Liberia.

scientific article published on February 2011

Evaluation of Plasmodium vivax Cell-Traversal Protein for Ookinetes and Sporozoites as a Preerythrocytic P. vivax Vaccine

scientific article published on 08 February 2017

Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility

scientific article (publication date: December 2011)

Expression of full-length Plasmodium falciparum P48/45 in P. berghei blood stages: A method to express and evaluate vaccine antigens

article by Ahmad Syibli Othman et al published 24 July 2018 in Molecular and Biochemical Parasitology

Failure to block adhesion of Plasmodium falciparum-infected erythrocytes to ICAM-1 with soluble ICAM-1 ⬇️

scientific article published on November 1, 1997

Functional Identification of the Plasmodium Centromere and Generation of a Plasmodium Artificial Chromosome

scientific article published in May 2010

Functional identification of the Plasmodium centromere and generation of a Plasmodium artificial chromosome

scientific article published in March 2010

Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes

scientific article

Generation of Transgenic Rodent Malaria Parasites Expressing Human Malaria Parasite Proteins

scientific article published on January 2015

Genetic engineering of attenuated malaria parasites for vaccination

scientific article (publication date: December 2012)

Hybridization and pre-zygotic reproductive barriers in Plasmodium

scientific article published in May 2015

Imaging & identification of malaria parasites using cellphone microscope with a ball lens

scientific article published in PLoS ONE

Imaging of the spleen in malaria.

scientific article published on 31 August 2013

Immunization with genetically attenuated P52-deficient Plasmodium berghei sporozoites induces a long-lasting effector memory CD8+ T cell response in the liver

scientific article published on 17 October 2011

In vivo and in vitro characterization of a Plasmodium liver stage-specific promoter

scientific article (publication date: 2015)

Integrated transcriptomic and proteomic analyses of P. falciparum gametocytes: molecular insight into sex-specific processes and translational repression

scientific article published on 13 June 2016

Investigating the evolution of apoptosis in malaria parasites: the importance of ecology

scientific article published on 16 November 2010

LC3-association with the parasitophorous vacuole membrane of Plasmodium berghei liver stages follows a noncanonical autophagy pathway

scientific article published on June 2017

Localisation and timing of expression of putative Plasmodium berghei rhoptry proteins in merozoites and sporozoites

scientific article (publication date: July 2009)

Long-term live imaging reveals cytosolic immune responses of host hepatocytes against Plasmodium infection and parasite escape mechanisms

scientific article

Longitudinal analysis of Plasmodium sporozoite motility in the dermis reveals component of blood vessel recognition

scientific article

Loss-of-function analyses defines vital and redundant functions of the Plasmodium rhomboid protease family.

scientific article

Mechanisms of gene regulation in Plasmodium.

scientific article published on August 2007

Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites

scientific article published on 29 August 2015

Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies

scientific article published on 28 November 2017

Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model

scientific article

Novel approaches to whole sporozoite vaccination against malaria.

scientific article published on 12 October 2015

OX40 Stimulation Enhances Protective Immune Responses Induced After Vaccination With Attenuated Malaria Parasites

article

Plasmodium falciparum Rab5B is an N-terminally myristoylated Rab GTPase that is targeted to the parasite's plasma and food vacuole membranes

scientific article (publication date: 2014)

Plasmodium falciparum subtilisin-like ookinete protein SOPT plays an important and conserved role during ookinete infection of the Anopheles stephensi midgut

scientific article published on 01 August 2018

Plasmodium liver load following parenteral sporozoite administration in rodents

scientific article published on 9 October 2012

Plasmodium products persist in the bone marrow and promote chronic bone loss.

scientific article

Prime and target immunization protects against liver-stage malaria in mice

scholarly article by Anita Gola et al published 26 September 2018 in Science Translational Medicine

Probabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites

scientific article published on 11 January 2018

Probabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites

scholarly article published 10 October 2017

Protective immunity differs between routes of administration of attenuated malaria parasites independent of parasite liver load.

scientific article

Proteome analysis of separated male and female gametocytes reveals novel sex-specific Plasmodium biology

scientific article published in June 2005

Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity

scientific article

Quantitative analysis of Plasmodium berghei liver stages by bioluminescence imaging

scientific article

Rapid Generation of Marker-Free P. falciparum Fluorescent Reporter Lines Using Modified CRISPR/Cas9 Constructs and Selection Protocol

scientific article

Rational development of a protective P. vivax vaccine evaluated with transgenic rodent parasite challenge models

scientific article

Reduced CD36-dependent tissue sequestration of Plasmodium-infected erythrocytes is detrimental to malaria parasite growth in vivo

scientific article published on 19 December 2011

Regulation of sexual development of Plasmodium by translational repression

scientific article

Removal of heterologous sequences from Plasmodium falciparum mutants using FLPe-recombinase

scientific article

Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance

scientific article

Screening inhibitors of P. berghei blood stages using bioluminescent reporter parasites

scientific article published in January 2013

Sequestration and Tissue Accumulation of Human Malaria Parasites: Can We Learn Anything from Rodent Models of Malaria?

scientific article (publication date: 30 September 2010)

Stage-specific transcription of distinct repertoires of a multigene family during Plasmodium life cycle.

scientific article

Standardization in generating and reporting genetically modified rodent malaria parasites: the RMgmDB database

scientific article

Tailoring a Plasmodium vivax Vaccine To Enhance Efficacy through a Combination of a CSP Virus-Like Particle and TRAP Viral Vectors

scientific article published in 2018

The 235 kDa rhoptry protein of Plasmodium (yoelii) yoelii: function at the junction.

scientific article

The Plasmodium falciparum Cell-Traversal Protein for Ookinetes and Sporozoites as a Candidate for Preerythrocytic and Transmission-Blocking Vaccines

scientific article

The Plasmodium falciparum male gametocyte protein P230p, a paralog of P230, is vital for ookinete formation and mosquito transmission

scientific article published in Scientific Reports

The apical organelles of malaria merozoites: host cell selection, invasion, host immunity and immune evasion.

scientific article

The subcellular location of ovalbumin in Plasmodium berghei blood stages influences the magnitude of T-cell responses

scientific article

The use of transgenic parasites in malaria vaccine research

scientific article

Three members of the 6-cys protein family of Plasmodium play a role in gamete fertility

scientific article

Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria

scientific article published on 19 December 2016

Transition of Plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein Pumilio

scientific article (publication date: May 2011)

Two Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage development

scientific article (publication date: May 2014)

Type II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoes

scientific article (publication date: May 2014)

Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole

scientific article (publication date: November 2016)

Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging

scientific article

Why are male malaria parasites in such a rush?: Sex-specific evolution and host-parasite interactions

scientific article

Paulina is supported by:

About Paulina

Help