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List of works by Michael Basler

A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis.

scientific article

Amelioration of autoimmunity with an inhibitor selectively targeting all active centres of the immunoproteasome

scientific article published on 15 October 2017

Analgesia in mice with experimental meningitis reduces pain without altering immune parameters

scientific article published on 24 March 2015

Attenuation of the cytotoxic T lymphocyte response to lymphocytic choriomeningitis virus in mice subjected to chronic social stress

scientific article published on 23 October 2010

Chaperone BAG6 is dispensable for MHC class I antigen processing and presentation

scientific article published on 17 November 2015

Co-inhibition of immunoproteasome subunits LMP2 and LMP7 is required to block autoimmunity

scientific article published on 02 October 2018

Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.

scientific article published on 13 April 2018

Evidence for an involvement of the ubiquitin-like modifier ISG15 in MHC class I antigen presentation

scientific article published on 20 July 2020

Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity ⬇️

scientific article published on February 17, 2012

Immuno- and constitutive proteasomes do not differ in their abilities to degrade ubiquitinated proteins

scientific article published on February 2013

Immunodominance of an antiviral cytotoxic T cell response is shaped by the kinetics of viral protein expression

scientific article published on November 2003

Immunoproteasome Inhibition Selectively Kills Human CD14+ Monocytes and as a Result Dampens IL-23 Secretion

scientific article published on 04 September 2019

Immunoproteasome inhibition prevents chronic antibody-mediated allograft rejection in renal transplantation

scientific article published on 4 December 2017

Immunoproteasome subunit LMP7 deficiency and inhibition suppresses Th1 and Th17 but enhances regulatory T cell differentiation

scientific article published on 14 September 2012

Immunoproteasome subunit deficiency has no influence on the canonical pathway of NF-κB activation.

scientific article published on 31 January 2017

Immunoproteasome-specific inhibitors and their application

scientific article published in January 2012

Immunoproteasomes are essential for survival and expansion of T cells in virus-infected mice

scientific article published on 11 November 2010

Inhibiting the immunoproteasome exacerbates the pathogenesis of systemic Candida albicans infection in mice.

scientific article published on 18 January 2016

Inhibition and deficiency of the immunoproteasome subunit LMP7 attenuates LCMV-induced meningitis

scientific article published on 14 October 2015

Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis

scientific article published on 16 January 2014

Long-lived signal peptide of lymphocytic choriomeningitis virus glycoprotein pGP-C.

scientific article

No prolongation of skin allograft survival by immunoproteasome inhibition in mice.

scientific article published on 2 June 2017

On the role of the immunoproteasome in transplant rejection

scientific article published on 15 September 2018

PLGA Particles in Immunotherapy

scientific article published in 2023

Prevention of experimental colitis by a selective inhibitor of the immunoproteasome

scientific article published on 4 June 2010

Proteasomes in immune cells: more than peptide producers?

scientific article

Recent insights how combined inhibition of immuno/proteasome subunits enables therapeutic efficacy

scientific article published on 25 August 2020

Reduced immunoproteasome formation and accumulation of immunoproteasomal precursors in the brains of lymphocytic choriomeningitis virus-infected mice

scientific article published on 29 September 2010

The Ubiquitin-like Modifier FAT10 Is Selectively Expressed in Medullary Thymic Epithelial Cells and Modifies T Cell Selection

scientific article published on 23 September 2015

The antiviral immune response in mice devoid of immunoproteasome activity

scientific article published on 19 October 2011

The expression profile of the ubiquitin-like modifier FAT10 in immune cells suggests cell type-specific functions.

scientific article published on 5 March 2018

The immunoproteasome in antigen processing and other immunological functions ⬇️

scientific article published on December 6, 2012

The immunoproteasome subunit LMP7 is required in the murine thymus for filling up a hole in the T cell repertoire

scientific article

The immunoproteasome: a novel drug target for autoimmune diseases

scientific article published on 12 October 2015

The proteasome inhibitor bortezomib enhances the susceptibility to viral infection

scientific article

The ubiquitin-like modifier FAT10 decorates autophagy-targeted Salmonella and contributes to Salmonella resistance in mice

scientific article published on 30 September 2014

Using Protease Inhibitors in Antigen Presentation Assays ⬇️

scientific article published on January 1, 2013

Why the structure but not the activity of the immunoproteasome subunit low molecular mass polypeptide 2 rescues antigen presentation

scientific article published on 6 July 2012

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