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List of works by Hans-Ulrich Schildhaus

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Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

scientific article
Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate

scientific article
Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p.V600E and non-p.V600E BRAFmutations

scientific article published on January 10, 2014
Harmonized PD-L1 immunohistochemistry for pulmonary squamous-cell and adenocarcinomas

scientific article published on 8 July 2016
Heterogeneous mechanisms of primary and acquired resistance to third-generation EGFR inhibitors

scientific article published on June 2016
Pelvic lymph node dissection for nodal oligometastatic prostate cancer detected by 68 Ga-PSMA-positron emission tomography/computerized tomography

scientific article published on September 10, 2015
β‐Catenin (CTNNB1) mutations and clinicopathological features of mesenteric desmoid‐type fibromatosis

scientific article published on September 28, 2012
Residual tumor cells are unique cellular targets in glioblastoma

scientific article published on August 2010
Fibroblast growth factor receptor 1 (FGFR1) amplification is a potential therapeutic target in small-cell lung cancer

scientific article published on July 26, 2013
miRNA-221 and miRNA-222 induce apoptosis via the KIT/AKT signalling pathway in gastrointestinal stromal tumours

scientific article
MET Amplification Status in Therapy-Naïve Adeno- and Squamous Cell Carcinomas of the Lung

scientific article published on December 9, 2014
Mutation analysis of gastrointestinal stromal tumors: increasing significance for risk assessment and effective targeted therapy

scientific article published on 14 August 2007
Lysine-specific demethylase 1 is highly expressed in solitary fibrous tumors, synovial sarcomas, rhabdomyosarcomas, desmoplastic small round cell tumors, and malignant peripheral nerve sheath tumors

scientific article published on 29 April 2011
Multicenter immunohistochemical ALK-testing of non-small-cell lung cancer shows high concordance after harmonization of techniques and interpretation criteria

scientific article published on November 2014
EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy

scientific article published on 23 July 2008
ROS1 rearrangements in lung adenocarcinoma: prognostic impact, therapeutic options and genetic variability

scientific article published in April 2015
Interlaboratory-concordance of PD-L1 immunohistochemistry for non-small cell lung cancer

scientific article published on 29 August 2017
A subset of gastrointestinal stromal tumors previously regarded as wild-type tumors carries somatic activating mutations in KIT exon 8 (p.D419del)

scientific article
Activating PDGFRA mutations in inflammatory fibroid polyps occur in exons 12, 14 and 18 and are associated with tumour localization

scientific article published on March 6, 2012
Post-transcriptional dysregulation by miRNAs is implicated in the pathogenesis of gastrointestinal stromal tumor [GIST]

scientific article published in 2013
Clear cell papillary renal cell carcinoma and renal angiomyoadenomatous tumor: two variants of a morphologic, immunohistochemical, and genetic distinct entity of renal cell carcinoma

scientific article published on July 2015
Pitfalls in mutational testing and reporting of common KIT and PDGFRA mutations in gastrointestinal stromal tumors

scientific article
Soft tissue sarcoma: from molecular diagnosis to selection of treatment. Pathological diagnosis of soft tissue sarcoma amid molecular biology and targeted therapies

scientific article published on October 1, 2010
Sensitive and specific detection of EML4-ALK rearrangements in non-small cell lung cancer (NSCLC) specimens by multiplex amplicon RNA massive parallel sequencing

scientific article published on 13 March 2014
Clinicopathological Characteristics of RET Rearranged Lung Cancer in European Patients

scientific article
Fibroblast Growth Factor Receptor 1 and Related Ligands in Small-Cell Lung Cancer

scientific article published on July 2015
Comparison of pre-analytical FFPE sample preparation methods and their impact on massively parallel sequencing in routine diagnostics

scientific article
FGFR2 is overexpressed in myxoid liposarcoma and inhibition of FGFR signaling impairs tumor growth in vitro

scientific article published on 8 May 2015
Impact of updated HER2 testing guidelines in breast cancer--re-evaluation of HERA trial fluorescence in situ hybridization data

scientific article
Clinicopathological and molecular features of a large cohort of gastrointestinal stromal tumors (GISTs) and review of the literature: BRAF mutations in KIT/PDGFRA wild-type GISTs are rare events

scientific article published on 31 January 2017
Chromogenic in situ hybridization is a reliable assay for detection of ALK rearrangements in adenocarcinomas of the lung

scientific article
Single-cell analysis of mtDNA deletion levels in sporadic amyotrophic lateral sclerosis

scientific article published in April 2004
SRC inhibition represents a potential therapeutic strategy in liposarcoma

scientific article
c-myc copy number gain is a powerful prognosticator of disease outcome in cervical dysplasia

scientific article
Activated RET and ROS: two new driver mutations in lung adenocarcinoma

scientific article
MET gene copy number alterations and expression of MET and hepatocyte growth factor are potential biomarkers in angiosarcomas and undifferentiated pleomorphic sarcomas

scientific article published on 6 April 2015
Squamous Cell Carcinoma of the Pancreas in a Patient with Germline BRCA2 Mutation-Response to Neoadjuvant Radiochemotherapy

scientific article
HR23b expression is a potential predictive biomarker for HDAC inhibitor treatment in mesenchymal tumours and is associated with response to vorinostat

scientific article published on 05 February 2016
High-resolution melting analysis is a sensitive diagnostic tool to detect imatinib-resistant and imatinib-sensitive PDGFRA exon 18 mutations in gastrointestinal stromal tumors

scientific article published on November 4, 2013
MET-GRB2 Signaling-Associated Complexes Correlate with Oncogenic MET Signaling and Sensitivity to MET Kinase Inhibitors

scientific article published on 29 August 2017
Ovarian-type epithelial tumours of the testis: immunohistochemical and molecular analysis of two serous borderline tumours of the testis

scientific article published on 22 July 2015
qPCR in gastrointestinal stromal tumors: Evaluation of reference genes and expression analysis of KIT and the alternative receptor tyrosine kinases FLT3, CSF1-R, PDGFRB, MET and AXL.

scientific article
Heterogeneity of KRAS Mutation Status in Rectal Cancer

scientific article
Diagnostic red flags: steroid-treated malignant CNS lymphoma mimicking autoimmune inflammatory demyelination

scientific article published on 18 February 2017
Massively parallel sequencing fails to detect minor resistant subclones in tissue samples prior to tyrosine kinase inhibitor therapy

scientific article
FGFR1 amplifications in squamous cell carcinomas of the lung: diagnostic and therapeutic implications

scientific article
Current Standard and Future Perspectives in the Treatment of Gastrointestinal Stromal Tumors

scientific article published on 07 April 2017
Challenging dedifferentiated liposarcoma identified by MDM2-amplification, a report of two cases

scientific article
Rhabdoid morphology in gastrointestinal stromal tumours (GISTs) is associated with PDGFRA mutations but does not imply aggressive behaviour

scientific article published on November 22, 2013
Partial Response to First-Line Crizotinib in an Elderly Male Patient with ROS1 Translocation-Positive Lung Cancer

scientific article published on January 2016

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