List of works - Akemi Ishida-Yamamoto

A homozygous nonsense mutation in the gene for Tmem79, a component for the lamellar granule secretory system, produces spontaneous eczema in an experimental model of atopic dermatitis

scientific journal article

A mutation in SNAP29, coding for a SNARE protein involved in intracellular trafficking, causes a novel neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma

scientific article

A novel protease inhibitor of the alpha2-macroglobulin family expressed in the human epidermis

scientific article

Activation of two caspase cascades, caspase 8/3/6 and caspase 9/3/6, during photodynamic therapy using a novel photosensitizer, ATX-S10(Na), in normal human keratinocytes

scientific article

Alopecia, neurological defects, and endocrinopathy syndrome caused by decreased expression of RBM28, a nucleolar protein associated with ribosome biogenesis

scientific article published on 24 April 2008

Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells

scientific article published on 27 October 2008

Autosomal recessive ichthyosis with hypotrichosis caused by a mutation in ST14, encoding type II transmembrane serine protease matriptase

scientific article published on 23 January 2007

Bone marrow transplantation for recessive dystrophic epidermolysis bullosa

scientific article

CD4+ T-cells from peripheral blood of a patient with psoriasis recognize keratin 14 peptide but not 'homologous' streptococcal M-protein epitope

scientific article published on December 2002

Close correlation of herpes zoster-induced voiding dysfunction with severity of zoster-related pain: A single faculty retrospective study

scientific article published on 28 May 2015

Cole Disease Results from Mutations in ENPP1.

scientific article published on 26 September 2013

Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response

scientific article

Corneodesmosomal cadherins are preferential targets of stratum corneum trypsin- and chymotrypsin-like hyperactivity in Netherton syndrome

scientific article (publication date: July 2006)

Cornoid lamellae associated with follicular infundibulum and acrosyringium in porokeratosis

scientific article

Cutaneous lesions of Kikuchi's disease: evolution of histopathological findings

scientific article published on 9 July 2014

Cutaneous necrotizing vasculitis as a manifestation of familial Mediterranean fever

scientific article published on 11 August 2014

Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting

scientific article published on 25 August 2013

Desmoglein 4 is expressed in highly differentiated keratinocytes and trichocytes in human epidermis and hair follicle

scientific article

Drug-induced hypersensitivity syndrome due to mexiletine associated with human herpes virus 6 and cytomegalovirus reactivation

scientific article published on April 2005

Epidermal lamellar granules transport different cargoes as distinct aggregates

scientific article published in May 2004

Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1.

scholarly article

Erythrokeratodermia variabilis et progressiva

scientific article published on March 2016

Expanding the phenotypic spectrum of Cx26 disorders: Bart-Pumphrey syndrome is caused by a novel missense mutation in GJB2.

scientific article

Fibroepithelioma-like changes occurring in perianal Paget's disease with rectal mucinous carcinoma: case report and review of 49 cases of extramammary Paget's disease

scientific article

Genetic skin diseases related to desmosomes and corneodesmosomes

scientific article published on 28 February 2014

Intercellular contact augments epidermal growth factor receptor (EGFR) and signal transducer and activator of transcription 3 (STAT3)-activation which increases podoplanin-expression in order to promote squamous cell carcinoma motility ⬇️

scientific article published on December 22, 2012

Intratumoral injection of IFN-β induces chemokine production in melanoma and augments the therapeutic efficacy of anti-PD-L1 mAb.

scientific article

Involvement of corneodesmosome degradation and lamellar granule transportation in the desquamation process ⬇️

scientific article (publication date: March 2011)

KRT14 haploinsufficiency results in increased susceptibility of keratinocytes to TNF-alpha-induced apoptosis and causes Naegeli-Franceschetti-Jadassohn syndrome

scientific article published on 29 November 2007

Kallikrein 8 is involved in skin desquamation in cooperation with other kallikreins

scientific journal article

LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum

scientific article

Lamellar Granule Secretion Starts before the Establishment of Tight Junction Barrier for Paracellular Tracers in Mammalian Epidermis ⬇️

scientific article published on February 6, 2012

Loricrin keratoderma: a novel disease entity characterized by nuclear accumulation of mutant loricrin

scientific article (publication date: February 2003)

Naegeli-Franceschetti-Jadassohn syndrome and dermatopathia pigmentosa reticularis: two allelic ectodermal dysplasias caused by dominant mutations in KRT14

scientific article

Order and disorder in corneocyte adhesion

scientific article published on 04 May 2011

Pathophysiology of generalized pustular psoriasis

scientific article

Periplakin gene targeting reveals a constituent of the cornified cell envelope dispensable for normal mouse development

scientific article

Photodynamic therapy using a novel photosensitizer, ATX-S10(Na): comparative effect with 5-aminolevulinic acid on squamous cell carcinoma cell line, SCC15, ultraviolet B-induced skin tumor, and phorbol ester-induced hyperproliferative skin.

scientific article

Prevalence of coronary artery calcification in Japanese patients with psoriasis: A close correlation with bilateral diagonal earlobe creases

scientific article published on 2 May 2017

Psoriatic architecture constructed by epidermal remodeling

scientific article published in August 2004

RIN2 deficiency results in macrocephaly, alopecia, cutis laxa, and scoliosis: MACS syndrome

scientific article published on 23 July 2009

Rab11 is associated with epidermal lamellar granules

scientific article

Reduction of E-cadherin by human defensin-5 in esophageal squamous cells

scientific article published on 16 August 2013

Revised nomenclature and classification of inherited ichthyoses: results of the First Ichthyosis Consensus Conference in Sorèze 2009.

scientific article

Roxithromycin decreases ultraviolet B irradiation-induced reactive oxygen intermediates production and apoptosis of keratinocytes

scientific article published on February 2004

Roxithromycin suppresses involucrin expression by modulation of activator protein-1 and nuclear factor-kappaB activities of keratinocytes

scientific article

Sarcoidosis during infliximab therapy for Crohn's disease

scientific article published on May 2010

Short Stature, Onychodysplasia, Facial Dysmorphism, and Hypotrichosis Syndrome Is Caused by a POC1A Mutation ⬇️

scientific article published on July 26, 2012

Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity

scientific article

Targeted deletion of the murine corneodesmosin gene delineates its essential role in skin and hair physiology

scholarly article

The biology and regulation of corneodesmosomes

scientific article

Ultraviolet B irradiation increases keratin 5 and keratin 14 expression through epidermal growth factor receptor of SV40-transformed human keratinocytes

scientific article published on 23 January 2002

Unique keratinization process in psoriasis: late differentiation markers are abolished because of the premature cell death

scientific article published on April 2004

Vesicular LL-37 contributes to inflammation of the lesional skin of palmoplantar pustulosis

scientific article

List of works by Akemi Ishida-Yamamoto

A homozygous nonsense mutation in the gene for Tmem79, a component for the lamellar granule secretory system, produces spontaneous eczema in an experimental model of atopic dermatitis

A mutation in SNAP29, coding for a SNARE protein involved in intracellular trafficking, causes a novel neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma

A novel protease inhibitor of the alpha2-macroglobulin family expressed in the human epidermis

Activation of two caspase cascades, caspase 8/3/6 and caspase 9/3/6, during photodynamic therapy using a novel photosensitizer, ATX-S10(Na), in normal human keratinocytes

Alopecia, neurological defects, and endocrinopathy syndrome caused by decreased expression of RBM28, a nucleolar protein associated with ribosome biogenesis

Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells

Autosomal recessive ichthyosis with hypotrichosis caused by a mutation in ST14, encoding type II transmembrane serine protease matriptase

Bone marrow transplantation for recessive dystrophic epidermolysis bullosa

CD4+ T-cells from peripheral blood of a patient with psoriasis recognize keratin 14 peptide but not 'homologous' streptococcal M-protein epitope

Close correlation of herpes zoster-induced voiding dysfunction with severity of zoster-related pain: A single faculty retrospective study

Cole Disease Results from Mutations in ENPP1.

Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response

Corneodesmosomal cadherins are preferential targets of stratum corneum trypsin- and chymotrypsin-like hyperactivity in Netherton syndrome

Cornoid lamellae associated with follicular infundibulum and acrosyringium in porokeratosis

Cutaneous lesions of Kikuchi's disease: evolution of histopathological findings

Cutaneous necrotizing vasculitis as a manifestation of familial Mediterranean fever

Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting

Desmoglein 4 is expressed in highly differentiated keratinocytes and trichocytes in human epidermis and hair follicle

Drug-induced hypersensitivity syndrome due to mexiletine associated with human herpes virus 6 and cytomegalovirus reactivation

Epidermal lamellar granules transport different cargoes as distinct aggregates

Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1.

Erythrokeratodermia variabilis et progressiva

Expanding the phenotypic spectrum of Cx26 disorders: Bart-Pumphrey syndrome is caused by a novel missense mutation in GJB2.

Fibroepithelioma-like changes occurring in perianal Paget's disease with rectal mucinous carcinoma: case report and review of 49 cases of extramammary Paget's disease

Genetic skin diseases related to desmosomes and corneodesmosomes

Intercellular contact augments epidermal growth factor receptor (EGFR) and signal transducer and activator of transcription 3 (STAT3)-activation which increases podoplanin-expression in order to promote squamous cell carcinoma motility ⬇️

Intratumoral injection of IFN-β induces chemokine production in melanoma and augments the therapeutic efficacy of anti-PD-L1 mAb.

Involvement of corneodesmosome degradation and lamellar granule transportation in the desquamation process ⬇️

KRT14 haploinsufficiency results in increased susceptibility of keratinocytes to TNF-alpha-induced apoptosis and causes Naegeli-Franceschetti-Jadassohn syndrome

Kallikrein 8 is involved in skin desquamation in cooperation with other kallikreins

LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum

Lamellar Granule Secretion Starts before the Establishment of Tight Junction Barrier for Paracellular Tracers in Mammalian Epidermis ⬇️

Loricrin keratoderma: a novel disease entity characterized by nuclear accumulation of mutant loricrin

Naegeli-Franceschetti-Jadassohn syndrome and dermatopathia pigmentosa reticularis: two allelic ectodermal dysplasias caused by dominant mutations in KRT14

Order and disorder in corneocyte adhesion

Pathophysiology of generalized pustular psoriasis

Periplakin gene targeting reveals a constituent of the cornified cell envelope dispensable for normal mouse development

Photodynamic therapy using a novel photosensitizer, ATX-S10(Na): comparative effect with 5-aminolevulinic acid on squamous cell carcinoma cell line, SCC15, ultraviolet B-induced skin tumor, and phorbol ester-induced hyperproliferative skin.

Prevalence of coronary artery calcification in Japanese patients with psoriasis: A close correlation with bilateral diagonal earlobe creases

Psoriatic architecture constructed by epidermal remodeling

RIN2 deficiency results in macrocephaly, alopecia, cutis laxa, and scoliosis: MACS syndrome

Rab11 is associated with epidermal lamellar granules

Reduction of E-cadherin by human defensin-5 in esophageal squamous cells

Revised nomenclature and classification of inherited ichthyoses: results of the First Ichthyosis Consensus Conference in Sorèze 2009.

Roxithromycin decreases ultraviolet B irradiation-induced reactive oxygen intermediates production and apoptosis of keratinocytes

Roxithromycin suppresses involucrin expression by modulation of activator protein-1 and nuclear factor-kappaB activities of keratinocytes

Sarcoidosis during infliximab therapy for Crohn's disease

Short Stature, Onychodysplasia, Facial Dysmorphism, and Hypotrichosis Syndrome Is Caused by a POC1A Mutation ⬇️

Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity

Targeted deletion of the murine corneodesmosin gene delineates its essential role in skin and hair physiology

The biology and regulation of corneodesmosomes

Ultraviolet B irradiation increases keratin 5 and keratin 14 expression through epidermal growth factor receptor of SV40-transformed human keratinocytes

Unique keratinization process in psoriasis: late differentiation markers are abolished because of the premature cell death

Vesicular LL-37 contributes to inflammation of the lesional skin of palmoplantar pustulosis