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List of works by Lorenz Trümper

A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling

scientific article published in June 2006

A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms

scientific article

A modular transcriptome map of mature B cell lymphomas

article

A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma

scientific article

ABC transporter ABCA3 is expressed in acute myeloid leukemia blast cells and participates in vesicular transport

scientific article

Aberrant Lymphocyte Enhancer–Binding Factor 1 Expression Is Characteristic for Sporadic Burkitt’s Lymphoma ⬇️

scientific article published on January 31, 2013

Abundant Expression of Spliced HDM2 in Hodgkin Lymphoma Cells does not Interfere with p14ARFand p53 Binding ⬇️

scientific article published on September 1, 2003

Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC.

scientific article published on 25 August 2017

Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis

scientific article

Autotransplant with and without induction chemotherapy in older multiple myeloma patients: long-term outcome of a randomized trial

scientific article published on 04 August 2016

B-cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice

scientific article published on 05 April 2016

B-lymphoma cells escape rituximab-triggered elimination by NK cells through increased HLA class I expression

scientific article

Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma

scientific article

CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera International Trial (MInT) Group

scientific article

Classical Hodgkin lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2.

scientific article

Clinical Impact of the Cell-of-Origin Classification and the MYC/ BCL2 Dual Expresser Status in Diffuse Large B-Cell Lymphoma Treated Within Prospective Clinical Trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group

scientific article published on 19 May 2017

DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control

scientific article

Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis

scientific article

Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteases

scientific article published on 25 March 2004

Escalated-dose BEACOPP in the treatment of patients with advanced-stage Hodgkin's lymphoma: 10 years of follow-up of the GHSG HD9 study

scientific article

Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3 ⬇️

scientific article published on August 25, 2011

Expression of endothelins and their receptors promotes an invasive phenotype of breast tumor cells but is insufficient to induce invasion in benign cells

scientific article published on November 2005

Frequency of del(12p) is commonly underestimated in myelodysplastic syndromes: Results from a German diagnostic study in comparison with an international control group

scientific article published on 10 September 2015

Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma

scientific article published on 26 March 2008

Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2.

scientific article published on 22 March 2018

Genetic polymorphisms in the amino acid transporters LAT1 and LAT2 in relation to the pharmacokinetics and side effects of melphalan

scientific article

High myc activity is an independent negative prognostic factor for diffuse large B cell lymphomas ⬇️

scientific article published on October 23, 2011

Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression data

scientific article

Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL.

scientific article published on 24 August 2010

Immunophenotypic and genetic characterization of a CD8 positive mantle cell lymphoma in a patient with concomitant Mycosis fungoides

scientific article

Increased myelotoxicity of idarubicin: is there a pharmacological basis? Results of a pharmacokinetic and an in vitro cytotoxicity study

scientific article published on 3 September 2003

Interleukin-10 Gene Polymorphisms are Associated With Freedom From Treatment Failure for Patients With Hodgkin Lymphoma ⬇️

scientific article published on January 8, 2013

Intestinal Pneumatosis Associated with Tuberculosis after Allogeneic Hematopoietic Stem Cell Transplantation

scientific article

Lenalidomide versus investigator's choice in relapsed or refractory mantle cell lymphoma (MCL-002; SPRINT): a phase 2, randomised, multicentre trial

scientific article

Loss of HLA-DR expression and immunoblastic morphology predict adverse outcome in diffuse large B-cell lymphoma - analyses of cases from two prospective randomized clinical trials

scientific article

Loss of p73 promotes dissemination of Myc-induced B cell lymphomas in mice ⬇️

scientific article

MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells

scientific article

MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma ⬇️

scientific article published on January 18, 2013

Modified BEAM with triple autologous stem cell transplantation for patients with relapsed aggressive non-Hodgkin lymphoma

scientific article published on 11 May 2016

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling

scientific article

Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell Lymphomas

scientific article published on 29 June 2016

Partial Response to First-Line Crizotinib in an Elderly Male Patient with ROS1 Translocation-Positive Lung Cancer

scientific article published on January 2016

Peripheral blood cytogenetics allows treatment monitoring and early identification of treatment failure to lenalidomide in MDS patients: results of the LE-MON-5 trial

scientific article

Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma

scientific article published on 21 February 2014

Recurrent deletions of the TNFSF7 and TNFSF9 genes in 19p13.3 in diffuse large B-cell and Burkitt lymphomas

scientific article

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

scientific article

Reduced Treatment Intensity in Patients with Early-Stage Hodgkin's Lymphoma ⬇️

scientific article published on August 12, 2010

Rituximab retherapy in patients with relapsed aggressive B cell and mantle cell lymphoma

scientific article

SOCS1 Mutation Subtypes Predict Divergent Outcomes in Diffuse Large B-Cell Lymphoma (DLBCL) Patients ⬇️

scientific article published on January 1, 2013

Secondary leukaemia after cure for locally advanced NSCLC: alkylating type secondary leukaemia after induction therapy with docetaxel and carboplatin for NSCLC IIIB.

scientific article published on May 2004

Significant dose Escalation of Idarubicin in the treatment of aggressive Non- Hodgkin Lymphoma leads to increased hematotoxicity without improvement in efficacy in comparison to standard CHOEP-14: 9-year follow up results of the CIVEP trial of the D

scientific article published on 03 January 2014

Six versus eight cycles of bi-weekly CHOP-14 with or without rituximab in elderly patients with aggressive CD20+ B-cell lymphomas: a randomised controlled trial (RICOVER-60).

scientific article

TP53 mutation and survival in aggressive B cell lymphoma

scientific article published on 14 June 2017

The PCBP1 gene encoding poly(rC) binding protein I is recurrently mutated in Burkitt lymphoma

scientific article published on 14 July 2015

Therapeutic options in relapsed or refractory peripheral T-cell lymphoma

scientific article published on 24 August 2014

USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma

scientific article published on 16 June 2016

Validation of cytogenetic risk groups according to International Prognostic Scoring Systems by peripheral blood CD34+FISH: results from a German diagnostic study in comparison with an international control group

scientific article published on 24 October 2014

Yttrium 90 ibritumomab tiuxetan (Zevalin): a new bullet in the fight against malignant lymphoma?

scientific article published on November 2007

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