List of works - Robert Grützmann

A common variant of PNPLA3 (p.I148M) is not associated with alcoholic chronic pancreatitis

scientific article

A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis

scientific article published on 16 March 2015

Activation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profiling

scientific article

An update on molecular research of pancreatic adenocarcinoma

scientific article published on June 2011

Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis

scientific article

Blood Glucose Homeostasis in the Course of Partial Pancreatectomy--Evidence for Surgically Reversible Diabetes Induced by Cholestasis

scientific article published on 6 August 2015

Chronic pancreatitis of the pancreatic remnant is an independent risk factor for pancreatic fistula after distal pancreatectomy

scientific article

Circulating methylated SEPT9 DNA in plasma is a biomarker for colorectal cancer

scientific article

DNA methylation biomarkers for blood-based colorectal cancer screening

scientific article

DNA methylation in pancreatic cancer: protocols for the isolation of DNA and bisulfite modification

scientific article published on January 2012

DNA microarray analysis of pancreatic malignancies

scientific article

Effect of Hospital Volume on In-hospital Morbidity and Mortality Following Pancreatic Surgery in Germany

scientific article published on 4 April 2017

Evaluation of central pancreatectomy and pancreatic enucleation as pancreatic resections--A comparison

scientific article published on 13 August 2015

Evaluation of survival in patients after pancreatic head resection for ductal adenocarcinoma

scientific article

Examination of apoptosis signaling in pancreatic cancer by computational signal transduction analysis

scientific article

Feedback within the inter-cellular communication and tumorigenesis in carcinomas

scientific article

Five primary human pancreatic adenocarcinoma cell lines established by the outgrowth method

scientific article published on 7 May 2011

Functional analysis of LOXL2 in pancreatic carcinoma

scientific article

Gene expression analysis of pancreatic cell lines reveals genes overexpressed in pancreatic cancer

scientific article published on 23 June 2005

Gene expression profiling of ampullary carcinomas classifies ampullary carcinomas into biliary-like and intestinal-like subtypes that are prognostic of outcome

scientific article published on 11 June 2013

Gene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarrays

scientific article

Genetic analyses of heme oxygenase 1 (HMOX1) in different forms of pancreatitis

scientific article

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis

scientific article

Genomic analyses identify molecular subtypes of pancreatic cancer

scientific article published on 24 February 2016

Google goes cancer: improving outcome prediction for cancer patients by network-based ranking of marker genes

scientific article

Improved protocol for laser microdissection of human pancreatic islets from surgical specimens

scientific article

Influence of Hospital Volume Effects and Minimum Caseload Requirements on Quality of Care in Pancreatic Surgery in Germany

scientific article published on 30 March 2017

Inhibition of MIF leads to cell cycle arrest and apoptosis in pancreatic cancer cells

scientific article

Integrated proteomic profiling of cell line conditioned media and pancreatic juice for the identification of pancreatic cancer biomarkers

scientific article

Intraductal papillary mucinous neoplasia (IPMN) of the pancreas: its diagnosis, treatment, and prognosis

scientific article published on 18 November 2011

Intraductal papillary mucinous tumors of the pancreas: biology, diagnosis, and treatment

scientific article published on 8 December 2010

Isolation of Human Islets from Partially Pancreatectomized Patients ⬇️

scientific article published on July 30, 2011

Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis

scientific article

Meta-analysis of microarray data on pancreatic cancer defines a set of commonly dysregulated genes

scientific article

Microarray-based gene expression profiling in pancreatic ductal carcinoma: status quo and perspectives

scientific article published on 24 January 2004

Molecular pathogenesis of pancreatic neuroendocrine tumors

scientific article

Multicenter study using paraffin-embedded tumor tissue testing PITX2 DNA methylation as a marker for outcome prediction in tamoxifen-treated, node-negative breast cancer patients

scientific article published on 18 August 2008

Nationwide In-hospital Mortality Following Pancreatic Surgery in Germany is Higher than Anticipated

scientific article

Outcome of invasive and noninvasive intraductal papillary-mucinous neoplasms of the pancreas (IPMN): a 10-year experience

scientific article published on October 2008

Pancreatic acinar cell carcinoma: a multi-institutional study

scientific article published on 03 June 2009

Pathogenic, immunologic, and clinical aspects of sepsis - update 2016.

scientific article published on 17 August 2016

Precursor lesions for sporadic pancreatic cancer: PanIN, IPMN, and MCN.

scientific article

Predictive factors for better bypass patency and limb salvage after prosthetic above-knee bypass reconstruction

scientific article

Primary and recurrent sporadic desmoids: Prognostic factors influencing recurrence-free survival after complete gross resection

scientific article

Prognostic relevance of minimal residual disease in colorectal cancer

scientific article

Prognostic significance of AGR2 in pancreatic ductal adenocarcinoma

scientific article

Quality of life in patients after pancreaticoduodenectomy for chronic pancreatitis

scientific article

Recent patents concerning diagnostic and therapeutic applications of aberrantly methylated sequences in pancreatic cancer

scientific article published on January 2008

Recent patents concerning targeted therapy of apoptosis resistance in pancreatic cancer

scientific article published on April 2011

Search for and identification of novel tumor-associated autoantigens

scientific article

Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay

scientific article published in 2008

Serum tumor markers in pancreatic cancer-recent discoveries

scientific article published on 02 June 2010

Simultaneous gene silencing of Bcl-2, XIAP and Survivin re-sensitizes pancreatic cancer cells towards apoptosis

scientific article

Simultaneous gene silencing of KRAS and anti-apoptotic genes as a multitarget therapy

scientific article published on 26 December 2015

Solid pseudopapillary neoplasms of the pancreas: a multi-institutional study of 21 patients

scientific article published on 08 May 2009

Structural templates predict novel protein interactions and targets from pancreas tumour gene expression data

scientific article

Survival analysis in rectal carcinoma after neoadjuvant chemoradiation: various methods with different results

scientific article published on 20 July 2017

Systematic identification and molecular characterization of genes differentially expressed in breast and ovarian cancer

scientific article

Systematic isolation of genes differentially expressed in normal and cancerous tissue of the pancreas

scientific article

The G Protein-Coupled Receptor RAI3 Is an Independent Prognostic Factor for Pancreatic Cancer Survival and Regulates Proliferation via STAT3 Phosphorylation

scientific article

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

scientific article

Tumor-associated CD75s- and iso-CD75s-gangliosides are potential targets for adjuvant therapy in pancreatic cancer

scientific article

Variants in CPA1 are strongly associated with early onset chronic pancreatitis

scientific article published on 18 August 2013

What is Changing in Indications and Treatment of Focal Nodular Hyperplasia of the Liver. Is There Any Place for Surgery?

scientific article

Whole genomes redefine the mutational landscape of pancreatic cancer

scientific article published in February 2015

List of works by Robert Grützmann

A common variant of PNPLA3 (p.I148M) is not associated with alcoholic chronic pancreatitis

A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis

Activation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profiling

An update on molecular research of pancreatic adenocarcinoma

Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis

Blood Glucose Homeostasis in the Course of Partial Pancreatectomy--Evidence for Surgically Reversible Diabetes Induced by Cholestasis

Chronic pancreatitis of the pancreatic remnant is an independent risk factor for pancreatic fistula after distal pancreatectomy

Circulating methylated SEPT9 DNA in plasma is a biomarker for colorectal cancer

DNA methylation biomarkers for blood-based colorectal cancer screening

DNA methylation in pancreatic cancer: protocols for the isolation of DNA and bisulfite modification

DNA microarray analysis of pancreatic malignancies

Effect of Hospital Volume on In-hospital Morbidity and Mortality Following Pancreatic Surgery in Germany

Evaluation of central pancreatectomy and pancreatic enucleation as pancreatic resections--A comparison

Evaluation of survival in patients after pancreatic head resection for ductal adenocarcinoma

Examination of apoptosis signaling in pancreatic cancer by computational signal transduction analysis

Feedback within the inter-cellular communication and tumorigenesis in carcinomas

Five primary human pancreatic adenocarcinoma cell lines established by the outgrowth method

Functional analysis of LOXL2 in pancreatic carcinoma

Gene expression analysis of pancreatic cell lines reveals genes overexpressed in pancreatic cancer

Gene expression profiling of ampullary carcinomas classifies ampullary carcinomas into biliary-like and intestinal-like subtypes that are prognostic of outcome

Gene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarrays

Genetic analyses of heme oxygenase 1 (HMOX1) in different forms of pancreatitis

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis

Genomic analyses identify molecular subtypes of pancreatic cancer

Google goes cancer: improving outcome prediction for cancer patients by network-based ranking of marker genes

Improved protocol for laser microdissection of human pancreatic islets from surgical specimens

Influence of Hospital Volume Effects and Minimum Caseload Requirements on Quality of Care in Pancreatic Surgery in Germany

Inhibition of MIF leads to cell cycle arrest and apoptosis in pancreatic cancer cells

Integrated proteomic profiling of cell line conditioned media and pancreatic juice for the identification of pancreatic cancer biomarkers

Intraductal papillary mucinous neoplasia (IPMN) of the pancreas: its diagnosis, treatment, and prognosis

Intraductal papillary mucinous tumors of the pancreas: biology, diagnosis, and treatment

Isolation of Human Islets from Partially Pancreatectomized Patients ⬇️

Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis

Meta-analysis of microarray data on pancreatic cancer defines a set of commonly dysregulated genes

Microarray-based gene expression profiling in pancreatic ductal carcinoma: status quo and perspectives

Molecular pathogenesis of pancreatic neuroendocrine tumors

Multicenter study using paraffin-embedded tumor tissue testing PITX2 DNA methylation as a marker for outcome prediction in tamoxifen-treated, node-negative breast cancer patients

Nationwide In-hospital Mortality Following Pancreatic Surgery in Germany is Higher than Anticipated

Outcome of invasive and noninvasive intraductal papillary-mucinous neoplasms of the pancreas (IPMN): a 10-year experience

Pancreatic acinar cell carcinoma: a multi-institutional study

Pathogenic, immunologic, and clinical aspects of sepsis - update 2016.

Precursor lesions for sporadic pancreatic cancer: PanIN, IPMN, and MCN.

Predictive factors for better bypass patency and limb salvage after prosthetic above-knee bypass reconstruction

Primary and recurrent sporadic desmoids: Prognostic factors influencing recurrence-free survival after complete gross resection

Prognostic relevance of minimal residual disease in colorectal cancer

Prognostic significance of AGR2 in pancreatic ductal adenocarcinoma

Quality of life in patients after pancreaticoduodenectomy for chronic pancreatitis

Recent patents concerning diagnostic and therapeutic applications of aberrantly methylated sequences in pancreatic cancer

Recent patents concerning targeted therapy of apoptosis resistance in pancreatic cancer

Search for and identification of novel tumor-associated autoantigens

Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay

Serum tumor markers in pancreatic cancer-recent discoveries

Simultaneous gene silencing of Bcl-2, XIAP and Survivin re-sensitizes pancreatic cancer cells towards apoptosis

Simultaneous gene silencing of KRAS and anti-apoptotic genes as a multitarget therapy

Solid pseudopapillary neoplasms of the pancreas: a multi-institutional study of 21 patients

Structural templates predict novel protein interactions and targets from pancreas tumour gene expression data

Survival analysis in rectal carcinoma after neoadjuvant chemoradiation: various methods with different results

Systematic identification and molecular characterization of genes differentially expressed in breast and ovarian cancer

Systematic isolation of genes differentially expressed in normal and cancerous tissue of the pancreas

The G Protein-Coupled Receptor RAI3 Is an Independent Prognostic Factor for Pancreatic Cancer Survival and Regulates Proliferation via STAT3 Phosphorylation

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

Tumor-associated CD75s- and iso-CD75s-gangliosides are potential targets for adjuvant therapy in pancreatic cancer

Variants in CPA1 are strongly associated with early onset chronic pancreatitis

What is Changing in Indications and Treatment of Focal Nodular Hyperplasia of the Liver. Is There Any Place for Surgery?

Whole genomes redefine the mutational landscape of pancreatic cancer