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List of works by Claudio Bucolo

1α,25-dihydroxyvitamin D<sub>3</sub> protects retinal ganglion cells in glaucomatous mice

scientific article published on 16 September 2021

A novel adamantane derivative attenuates retinal ischemia-reperfusion damage in the rat retina through sigma1 receptors

scientific article published on 06 March 2006

A water-soluble carbon monoxide-releasing molecule (CORM-3) lowers intraocular pressure in rabbits.

scientific article

Acidic Mammalian chitinase and the eye: implications for ocular inflammatory diseases

scientific article published on 25 July 2011

Acidic mammalian chitinase in dry eye conditions

scientific article

Activation of the VEGF-A/ERK/PLA2 Axis Mediates Early Retinal Endothelial Cell Damage Induced by High Glucose: New Insight from an In Vitro Model of Diabetic Retinopathy

scientific article published on 13 October 2020

Aflibercept regulates retinal inflammation elicited by high glucose via the PlGF/ERK pathway

scientific article published on 25 July 2019

Aflibercept, bevacizumab and ranibizumab prevent glucose-induced damage in human retinal pericytes in vitro, through a PLA2/COX-2/VEGF-A pathway

scientific article published on 6 June 2015

Antioxidant and Osmoprotecting Activity of Taurine in Dry Eye Models

scientific article

Apixaban Enhances Vasodilatation Mediated by Protease-Activated Receptor 2 in Isolated Rat Arteries

scientific article published on 18 July 2017

Behavioural and neurochemical changes induced by stress-related conditions are counteracted by the neurokinin-2 receptor antagonist saredutant.

scientific article published on 14 June 2012

Biocompatibility and biodegradation of intravitreal hyaluronan implants in rabbits.

scientific article

Blood-retinal barrier protection against high glucose damage: The role of P2X7 receptor

scientific article published on 11 July 2019

Buspirone Counteracts MK-801-Induced Schizophrenia-Like Phenotypes through Dopamine D3 Receptor Blockade.

scientific article published on 4 October 2017

Carbon monoxide and the eye: Implications for glaucoma therapy.

scientific article published on 02 February 2011

Carnosine Decreases PMA-Induced Oxidative Stress and Inflammation in Murine Macrophages

scientific article published on 06 August 2019

Cationic solid lipid nanoparticles enhance ocular hypotensive effect of melatonin in rabbit

scientific article published on 15 November 2014

Characterization and in-vivo ocular absorption of liposome-encapsulated acyclovir

scientific article published on 01 May 1999

Chitinase levels in the tears of subjects with ocular allergies

scientific article published in February 2008

Comparative Safety of Bevacizumab, Ranibizumab, and Aflibercept for Treatment of Neovascular Age-Related Macular Degeneration (AMD): A Systematic Review and Network Meta-Analysis of Direct Comparative Studies

scientific article published on 18 May 2020

Computational systems biology approach to identify novel pharmacological targets for diabetic retinopathy

scientific article published on 15 September 2018

Contribution of alpha4beta1 integrin to the antiallergic effect of levocabastine.

scientific article

Controversies in Glaucoma: Current Medical Treatment and Drug Development.

scientific article published on 08 September 2015

Curcumin prevents high glucose damage in retinal pigment epithelial cells through ERK1/2-mediated activation of the Nrf2/HO-1 pathway

scientific article published on 15 February 2019

Davunetide (NAP) protects the retina against early diabetic injury by reducing apoptotic death

scientific article published on 02 February 2014

Development and validation of an RP-HPLC-UV method for the determination of BOL-303225-A, a new coumarin-based anti-inflammatory drug, in rat plasma

scientific article published in April 2007

Different Retinal Expression Patterns of IL-1α, IL-1β, and Their Receptors in a Rat Model of Type 1 STZ-Induced Diabetes

scientific article published on 13 February 2015

Dopamine D(3) receptor as a new pharmacological target for the treatment of depression.

scientific article published on 18 July 2013

Dopamine D3 receptor is necessary for ethanol consumption: an approach with buspirone

scientific article

Dopamine D3 receptor-dependent changes in alpha6 GABAA subunit expression in striatum modulate anxiety-like behaviour: Responsiveness and tolerance to diazepam.

scientific article published on 15 November 2014

Dopamine outside the brain: The eye, cardiovascular system and endocrine pancreas

scientific article published on 09 July 2019

Dopamine-₃ receptor modulates intraocular pressure: implications for glaucoma

scientific article published on 8 December 2011

Dopaminergic-GABAergic interplay and alcohol binge drinking

scientific article published on 12 January 2019

Early changes in pituitary adenylate cyclase-activating peptide, vasoactive intestinal peptide and related receptors expression in retina of streptozotocin-induced diabetic rats ⬇️

scientific article published on June 18, 2012

Effect of chitinase inhibitors on endotoxin-induced uveitis (EIU) in rabbits

scientific article

Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells

scientific article published on 12 October 2017

Effects of Topical Fucosyl-Lactose, a Milk Oligosaccharide, on Dry Eye Model: An Example of Nutraceutical Candidate

scientific article

Effects of cloricromene, a coumarin derivative, on endotoxin-induced uveitis in Lewis rats

scientific article published in March 2003

Effects of hyaluronan on free-radical formation, corneal endothelium damage, and inflammation parameters after phacoemulsification in rabbits

scientific article published in April 2004

Effects of neurosteroids on ischemia-reperfusion injury in the rat retina: role of sigma1 recognition sites

scientific article published in September 2004

Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation.

scientific article published on 19 February 2015

Effects of topical indomethacin, bromfenac and nepafenac on lipopolysaccharide-induced ocular inflammation

scientific article published on 12 February 2014

Enhanced ocular anti-inflammatory activity of ibuprofen carried by an Eudragit RS100 nanoparticle suspension

scientific article published in September 2002

Enhancement of availability of cloricromene at brain level by a lipophilic prodrug

scientific article published in July 2006

Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats

scientific article

Eudragit RL100 nanoparticle system for the ophthalmic delivery of cloricromene

scientific article published in July 2004

Eudragit RS100 nanosuspensions for the ophthalmic controlled delivery of ibuprofen

scientific article

Evaluation of cell tolerability of a series of lipoamino acids using biological membranes and a biomembrane model

scientific article

Flurbiprofen-loaded acrylate polymer nanosuspensions for ophthalmic application

scientific article published in August 2002

Focus on molecules: heme oxygenase-1

scientific article published on 15 August 2009

Folate status in type 2 diabetic patients with and without retinopathy.

scientific article

Fortified extract of red berry, Ginkgo biloba, and white willow bark in experimental early diabetic retinopathy

scientific article published on 23 May 2013

Gabapentin Attenuates Ocular Inflammation: In vitro and In vivo Studies.

scientific article published on 4 April 2017

Genetic blockade of the dopamine D3 receptor enhances hippocampal expression of PACAP and receptors and alters their cortical distribution

scientific article published on 21 December 2015

Hemin, an inducer of heme oxygenase-1, lowers intraocular pressure in rabbits

scientific article

Homocysteine serum levels in diabetic patients with non proliferative, proliferative and without retinopathy

scientific article

Homology Modeling of Dopamine D2 and D3 Receptors: Molecular Dynamics Refinement and Docking Evaluation ⬇️

scientific article published on September 6, 2012

Hyaluronan-induced stimulation of corneal wound healing is a pure pharmacological effect

scientific article

Hydroxyl radical scavenging activity of a new ophthalmic viscosurgical device

scientific article published in February 2007

In vivo ocular efficacy profile of mapracorat, a novel selective glucocorticoid receptor agonist, in rabbit models of ocular disease

scientific article published on 14 March 2011

Influence of different surfactants on the technological properties and in vivo ocular tolerability of lipid nanoparticles

scientific article published in August 2014

Influence of preparation conditions on acyclovir-loaded poly-d,l-lactic acid nanospheres and effect of PEG coating on ocular drug bioavailability

scientific article published in April 2003

Innovative Nanoparticles Enhance N-Palmitoylethanolamide Intraocular Delivery.

scientific article published on 28 March 2018

Intravitreal Triamcinolone Acetonide in the Treatment of Ophthalmic Inflammatory Diseases with Macular Edema: A Meta-Analysis Study

scientific article published on 31 March 2015

LATE-ONSET OCULAR HYPERTENSION AFTER VITRECTOMY: A Multicenter Study of 6,048 Eyes

scientific article published on 01 November 2019

Lipoprotein(a) serum levels in diabetic patients with retinopathy

scientific article published on 05 June 2013

Long-term efficacy and safety profile of multiple injections of intravitreal dexamethasone implant to manage diabetic macular edema: A systematic review of real-world studies

scientific article published on 20 November 2018

Long-term efficacy of latanoprost in primary congenital glaucoma

scientific article published on 25 October 2013

Low levels of 17-β-oestradiol, oestrone and testosterone correlate with severe evaporative dysfunctional tear syndrome in postmenopausal women: a case-control study.

scientific article published on 3 January 2014

Metal fume fever

scientific article published on June 2013

MicroRNA target prediction in glaucoma

scientific article

MicroRNAs in the Vitreous Humor of Patients with Retinal Detachment and a Different Grading of Proliferative Vitreoretinopathy: A Pilot Study

scientific article published on 22 May 2020

Modulation of IL-1β and VEGF expression in rat diabetic retinopathy after PACAP administration.

scientific article published on 27 September 2017

Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach

scientific article

Morphine-induced ocular hypotension is modulated by nitric oxide and carbon monoxide: role of mu3 receptors

scientific article published in February 2010

NAP modulates hyperglycemic-inflammatory event of diabetic retina by counteracting outer blood retinal barrier damage

scientific article published on 30 October 2018

Nanosystems based on siRNA silencing HuR expression counteract diabetic retinopathy in rat.

scientific article published on 27 July 2016

Nap Interferes with Hypoxia-Inducible Factors and VEGF Expression in Retina of Diabetic Rats.

scientific article published on December 2016

Neuroactive steroids protect retinal pigment epithelium against oxidative stress

scientific article published on August 2005

Neuroactive steroids protect retinal tissue through sigma1 receptors

scientific article published on 01 March 2007

New coumarin-based anti-inflammatory drug: putative antagonist of the integrins alphaLbeta2 and alphaMbeta2.

scientific article published in November 2008

Novel ophthalmic formulation of myriocin: implications in retinitis pigmentosa

scientific article published on 01 December 2019

Novel polysaccharides-based viscoelastic formulations for ophthalmic surgery: rheological characterization.

scientific article

Novel therapeutics in glaucoma management

scientific article published on 15 September 2017

Nrf2 activators modulate oxidative stress responses and bioenergetic profiles of human retinal epithelial cells cultured in normal or high glucose conditions

scientific article published on 15 July 2015

Ocular Formulation Based on Palmitoylethanolamide-Loaded Nanostructured Lipid Carriers: Technological and Pharmacological Profile

scientific article published on 08 February 2020

Ocular Pharmacological Profile of Hydrocortisone in Dry Eye Disease

scientific article published on 18 October 2019

Ocular drug delivery: a clue from nanotechnology ⬇️

scientific article published on October 25, 2012

Ocular hypotensive action of topical flunarizine in the rabbit: role of sigma 1 recognition sites

scientific article published in December 2002

Ocular pharmacokinetics profile of different indomethacin topical formulations

scientific article

Ocular pharmacology: Cinderella becomes the queen

scientific article published on 01 September 2016

Ocular tolerability of Eudragit RS100 and RL100 nanosuspensions as carriers for ophthalmic controlled drug delivery

scientific article published on 01 December 2002

Omega-3 fatty acids and depression: scientific evidence and biological mechanisms

scientific article

P2X7 receptor antagonism: Implications in diabetic retinopathy

scientific article published on 4 May 2017

PACAP Modulates Expression of Hypoxia-Inducible Factors in Streptozotocin-Induced Diabetic Rat Retina

scientific article published on 23 July 2015

POOLED ESTIMATES OF INCIDENCE OF ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTION OF ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR AGENTS WITH AND WITHOUT TOPICAL ANTIBIOTIC PROPHYLAXIS.

scientific article

Pain Following the Use of Anesthesia Formulation Among Individuals Undergoing Cataract Surgery: A Randomized Controlled Trial

scientific article published on 16 April 2020

Pharmacological evaluation of a new timolol/pilocarpine formulation

scientific article published on 01 January 1998

Pharmacological management of ocular hypertension: current approaches and future prospective

scientific article published on 12 October 2012

Polymeric nanoparticles augment the ocular hypotensive effect of melatonin in rabbits

scientific article published on 16 October 2012

Possible involvement of nitric oxide in morphine-induced miosis and reduction of intraocular pressure in rabbits

scientific article published on 3 March 2006

Potential drug mechanism(s) targeting the contractile status of hepatic stellate cells ⬇️

scientific article published on October 25, 2012

Prognostic significance of deregulated microRNAs in uveal melanomas

scientific article published on 11 February 2019

Protective effect of PACAP-38 on retinal pigmented epithelium in an in vitro and in vivo model of diabetic retinopathy through EGFR-dependent mechanism

scientific article published on 24 June 2019

Protective effects of a coumarin derivative in diabetic rats

scientific article published on 11 March 2009

Protective effects of the sigma agonist Pre-084 in the rat retina.

scientific article published on 23 May 2007

Rapid determination of nimesulide in rabbit aqueous humor by liquid chromatography

scientific article published in May 2004

Rapid high-performance liquid chromatographic assay of dorzolamide in rabbit aqueous humor.

scientific article

Regulation of intraocular pressure in mice: structural analysis of dopaminergic and serotonergic systems in response to cabergoline.

scientific article published on 17 August 2013

Regulation of vascular tone in rabbit ophthalmic artery: cross talk of endogenous and exogenous gas mediators

scientific article published on 29 October 2014

Retinal Protection and Distribution of Curcumin in Vitro and in Vivo

scientific article published on 22 June 2018

Retinal and Circulating miRNAs in Age-Related Macular Degeneration: An In vivo Animal and Human Study

scientific article published on 30 March 2017

Retinal and circulating miRNA expression patterns in diabetic retinopathy: An in silico and in vivo approach

scientific article published on 09 May 2019

Retinal and systemic pharmacokinetics of the anti-inflammatory drug cloricromene following oral administration in the rat and rabbit

scientific article published on 01 June 2007

Reversible inhibition of vasoconstriction by thiazolidinediones related to PI3K/Akt inhibition in vascular smooth muscle cells

scientific article

Role of omega-3 fatty acids in the treatment of depressive disorders: a comprehensive meta-analysis of randomized clinical trials

scientific article

Role of phospholipases A2 in diabetic retinopathy: in vitro and in vivo studies

scientific article published on 25 September 2013

Safety profile assessment of buflomedil: an overview of adverse reactions between 1975 and 2011.

scientific article published on 31 July 2012

Sigma receptor ligands protect human retinal cells against oxidative stress

scientific article published in February 2006

Simple determination of riluzole in rat brain by high-performance liquid chromatography and spectrophotometric detection

scientific article

Simultaneous determination of cloricromene and its active metabolite in rabbit aqueous humor by high-performance liquid chromatography

scientific article published in February 2002

Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells

scientific article

Sulodexide prevents activation of the PLA2/COX-2/VEGF inflammatory pathway in human retinal endothelial cells by blocking the effect of AGE/RAGE.

scientific article

Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents

scientific article published on 01 July 2019

Systemic omega-6 essential fatty acid treatment and pge1 tear content in Sjögren's syndrome patients

scientific article published in December 2005

TGF-β1 prevents rat retinal insult induced by amyloid-β (1-42) oligomers.

scientific article published on February 2016

The PKCbeta/HuR/VEGF pathway in diabetic retinopathy.

scientific article published on July 2010

The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome

scientific article published in PLoS ONE

The antineoplastic drug flavopiridol reverses memory impairment induced by Amyloid-ß1-42 oligomers in mice.

scientific article published on 10 February 2016

The effect of ganglioside on oxidation-induced permeability changes in lens and in epithelial cells of lens and retina

scientific article published on 01 June 1994

The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans

scientific article published on 06 September 2019

Topical Ocular Delivery of TGF-β1 to the Back of the Eye: Implications in Age-Related Neurodegenerative Diseases

scientific article published on 30 September 2017

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