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List of works by Luigi Tornillo

A simple and reproducible scoring system for EGFR in colorectal cancer: application to prognosis and prediction of response to preoperative brachytherapy.

scientific article published on 20 February 2007

A spectrum of histopathologic findings in autoimmune liver disease

scientific article published on 01 November 2000

Absence of myeloperoxidase and CD8 positive cells in colorectal cancer infiltrates identifies patients with severe prognosis.

scientific article

Activation of Pro-Inflammatory and Anti-Inflammatory Cytokines in Host Organs During Chronic Allograft Rejection: Role of Endothelin Receptor Signaling

scientific article published on 01 May 2005

An unusual association of malignant gastrointestinal neuroectodermal tumor (clear cell sarcoma-like) and Ewing sarcoma.

scientific article published on 17 June 2015

An update on molecular genetics of gastrointestinal stromal tumours.

scientific article published on June 2006

Bioreactor-engineered cancer tissue-like structures mimic phenotypes, gene expression profiles and drug resistance patterns observed "in vivo".

scientific article published on 20 May 2015

Case report: appearance of an intestinal metastasis from intrahepatic cholangiocarcinoma occurring 5 years after resection of the primary tumor

scientific article published on 01 July 2010

Chromosomal alterations in hepatocellular nodules by comparative genomic hybridization: high-grade dysplastic nodules represent early stages of hepatocellular carcinoma.

scientific article published in May 2002

Chromosomal imbalances in small cell carcinomas of the urinary bladder

scientific article published on 01 October 1999

Chromosomal instability in gastric mucosa-associated lymphoid tissue lymphomas: a fluorescent in situ hybridization study using a tissue microarray approach

scientific article

Clinical features and genotype-phenotype correlations in children with progressive familial intrahepatic cholestasis type 3 related to ABCB4 mutations

scientific article published in January 2011

Clinical impact of programmed cell death ligand 1 expression in colorectal cancer.

scientific article

Clinical significance of cell cycle- and apoptosis-related markers in biliary tract cancer: a tissue microarray-based approach revealing a distinctive immunophenotype for intrahepatic and extrahepatic cholangiocarcinomas

scientific article published on 01 November 2008

Clinicopathologic and immunohistochemical study of surgically treated primary gastric MALT lymphoma

scientific article published on 01 June 2003

Clinicopathological Features and Metastatic Pattern of Hepatocellular Carcinoma: An Autopsy Study of 398 Patients

scientific article published on 18 June 2016

Close association between HER-2 amplification and overexpression in human tumors of non-breast origin

scientific article published on 01 February 2007

Co-overexpression of p21 and Ki-67 in head and neck squamous cell carcinoma relative to a significantly poor prognosis

scientific article published in February 2011

Coexistence of primary gastric giant cell-rich leiomyosarcoma and gastrointestinal stromal tumor: report of a very rare combination and review of the literature.

scientific article published on 07 July 2011

Colorectal carcinoma infiltration by myeloperoxidase-expressing neutrophil granulocytes is associated with favorable prognosis

scientific article published on 12 September 2013

Combined histomorphologic and immunohistochemical phenotype to predict the presence of vascular invasion in colon cancer

scientific article published in June 2009

Comparative genomic hybridization analysis of hepatoblastoma reveals high frequency of X-chromosome gains and similarities between epithelial and stromal components

scientific article published on 01 September 2003

Constitutive Notch2 signaling induces hepatic tumors in mice

scientific article published on 14 March 2013

Defective infiltration of natural killer cells in MICA/B-positive renal cell carcinoma involves beta(2)-integrin-mediated interaction.

scientific article published on July 2009

Diagnostic value of HSP70, glypican 3, and glutamine synthetase in hepatocellular nodules in cirrhosis

scientific article published on 01 March 2007

Differential cell cycle and proliferation marker expression in ductal pancreatic adenocarcinoma and pancreatic intraepithelial neoplasia (PanIN)

scientific article published on 01 April 2010

Differential significance of tumour infiltrating lymphocytes in sporadic mismatch repair deficient versus proficient colorectal cancers: A potential role for dysregulation of the transforming growth factor-β pathway

scientific article published on 12 January 2007

Diffuse minute clear cell proliferation in kidney: case report and review of literature.

scientific article published on 09 April 2008

Disruption of Notch1 Induces Vascular Remodeling, Intussusceptive Angiogenesis, and Angiosarcomas in Livers of Mice

scientific article published on 12 January 2012

Downregulation of the endothelial genes Notch1 and ephrinB2 in patients with nodular regenerative hyperplasia

scientific article published on 21 July 2013

Dual role of tumour-infiltrating T helper 17 cells in human colorectal cancer

scientific article published on 30 December 2015

Effect of EpCAM, CD44, CD133 and CD166 expression on patient survival in tumours of the ampulla of Vater

scientific article

Endothelin inhibition delays onset of hyperglycemia and associated vascular injury in type I diabetes: evidence for endothelin release by pancreatic islet beta-cells

scientific article published in August 2005

Enhanced expression of ANO1 in head and neck squamous cell carcinoma causes cell migration and correlates with poor prognosis

scientific article

EphB2 expression across 138 human tumor types in a tissue microarray: high levels of expression in gastrointestinal cancers

scientific article published in September 2005

Expression of CD24, P-cadherin and S100A4 in tumors of the ampulla of Vater

scientific article

Expression of Voltage-Gated Potassium Channels in Human and Mouse Colonic Carcinoma

scientific article published on 01 February 2007

Fatal herpes simplex virus hepatitis complicating chemotherapy with weekly docetaxel

scientific article

Frequency, phenotype, and genotype of minute gastrointestinal stromal tumors in the stomach: an autopsy study.

scientific article

Frequent high-level expression of the immunotherapeutic target Ep-CAM in colon, stomach, prostate and lung cancers.

scientific article published on January 2006

GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer.

scientific article

Galectin-1 and its involvement in hepatocellular carcinoma aggressiveness

scientific article

Glypican 3 expression in human nonneoplastic, preneoplastic, and neoplastic tissues: a tissue microarray analysis of 4,387 tissue samples

scientific article published on 01 June 2008

HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer

scientific article published on August 2006

HLA class II antigen expression in colorectal carcinoma tumors as a favorable prognostic marker

scientific article published on January 2014

HOX D13 expression across 79 tumor tissue types

scientific article published in October 2009

Hands-On Experience: Accreditation of Pathology Laboratories according to ISO 15189.

scientific article published on 7 December 2016

Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation

scientific article published on 18 July 2016

Hepatocyte paraffin 1 expression in human normal and neoplastic tissues: tissue microarray analysis on 3,940 tissue samples

scientific article published on 01 November 2004

Hepatoid adenocarcinoma with liver metastasis mimicking hepatocellular carcinoma: an immunohistochemical and molecular study of eight cases

scientific article published on 01 October 2003

High frequency of CD8 positive lymphocyte infiltration correlates with lack of lymph node involvement in early rectal cancer

scientific article

High frequency of tumor-infiltrating FOXP3(+) regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients

scientific article published on 01 June 2010

High myeloperoxidase positive cell infiltration in colorectal cancer is an independent favorable prognostic factor.

scientific article

Histopathologic features and microsatellite instability of cancers of the papilla of vater and their precursor lesions

scientific article published in May 2009

Human Papillomavirus (HPV) Detection in Cytologic Specimens: Similarities and Differences of Available Methodology

scientific article

Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment.

scientific article published on 31 March 2014

Immunophenotyping and oncogene amplifications in tumors of the papilla of Vater.

scientific article

Impaired vascular function in normoglycemic mice prone to autoimmune diabetes: Role of nitric oxide

Incarcerated umbilical hernia of unexpected origin: a primitive neuroectodermal tumor with early recurrence.

scientific article published on 6 January 2014

Infiltration by interleukin-22 producing T cells promotes neutrophil recruitment and predicts favorable clinical outcome in human colorectal cancer

scientific article published on 24 August 2020

Interferon-γ-stimulated genes, but not USP18, are expressed in livers of patients with acute hepatitis C.

scientific article published on 4 June 2012

Is immunohistochemical epidermal growth factor receptor expression overestimated as a prognostic factor in head-neck squamous cell carcinoma? A retrospective analysis based on a tissue microarray of 365 carcinomas

scientific article published on 11 July 2008

Is the improved prognosis of p16 positive oropharyngeal squamous cell carcinoma dependent of the treatment modality?

scientific article published in March 2010

KIT, PDGFRalpha and EGFR analysis in nephroblastoma

scientific article

KRAS mutation testing in colorectal cancer: comparison of the results obtained using 3 different methods for the analysis of codons G12 and G13.

scientific article published in March 2012

Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients

scientific article

Loss of APAF-1 expression is associated with tumour progression and adverse prognosis in colorectal cancer

scientific article published on 12 March 2007

Loss of Raf-1 Kinase Inhibitor Protein Expression Is Associated With Tumor Progression and Metastasis in Colorectal Cancer

scientific article published on 01 May 2007

Loss of the CBX7 protein expression correlates with a more aggressive phenotype in pancreatic cancer.

scientific article published on 23 February 2010

Low Expression of Programmed Death 1 (PD-1), PD-1 Ligand 1 (PD-L1), and Low CD8+ T Lymphocyte Infiltration Identify a Subgroup of Patients With Gastric and Esophageal Adenocarcinoma With Severe Prognosis

scientific article published on 28 April 2020

MAGE-A10 is a nuclear protein frequently expressed in high percentages of tumor cells in lung, skin and urothelial malignancies.

scientific article published on 12 January 2011

Melanoma cells inhibit NK cell functions

scientific article published on 09 October 2012

Microscopic gastrointestinal stromal tumors in esophageal and intestinal surgical resection specimens: a clinicopathologic, immunohistochemical, and molecular study of 19 lesions

scientific article published on 01 June 2008

Multiple sporadic gastrointestinal stromal tumors (GISTs) of the proximal stomach are caused by different somatic KIT mutations suggesting a field effect

article

Multiple sporadic gastrointestinal stromal tumours arising at different gastrointestinal sites: pattern of involvement of the muscularis propria as a clue to independent primary GISTs.

scientific article

NK cells and T cells cooperate during the clinical course of colorectal cancer

scientific article

NY-ESO-1/LAGE-1 coexpression with MAGE-A cancer/testis antigens: a tissue microarray study

scientific article published on 01 July 2005

Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice

article

OX40 expression enhances the prognostic significance of CD8 positive lymphocyte infiltration in colorectal cancer

scientific article published on 30 September 2015

Overexpression of the receptor for hyaluronic acid mediated motility is an independent adverse prognostic factor in colorectal cancer

scientific article published on 09 June 2006

PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients

scientific article published on 28 October 2014

PED is overexpressed and mediates TRAIL resistance in human non-small cell lung cancer

scientific article published on 15 February 2008

Patterns of gene amplification in gastrointestinal stromal tumors (GIST)

scientific article published on 01 July 2005

Patterns of liver infiltration in lymphoproliferative disease.

scientific article published on 06 June 2008

Primary rhabdoid tumour of the skin in a 14-month-old child

scientific article published on 01 January 1994

Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer.

scientific article

Prognostic significance of mammalian sterile20-like kinase 1 in colorectal cancer.

scientific article published on 2 February 2007

Prognostic significance of mucins in colorectal cancer with different DNA mismatch-repair status.

scientific article

Prognostic significance of the wnt signalling pathway molecules APC, beta-catenin and E-cadherin in colorectal cancer: a tissue microarray-based analysis.

scientific article published in March 2007

Prognostic value of apoptotic index in cutaneous basal cell carcinomas of head and neck

scientific article published on November 1999

Prognostic value of cell cycle and apoptosis regulatory proteins in mismatch repair-proficient colorectal cancer: a tissue microarray-based approach.

scientific article published in January 2007

Role of RHAMM within the hierarchy of well-established prognostic factors in colorectal cancer

scientific article published on 24 April 2008

Role of the mitogen-activated protein kinase and phosphoinositide 3-kinase/AKT pathways downstream molecules, phosphorylated extracellular signal–regulated kinase, and phosphorylated AKT in colorectal cancer—A tissue microarray–based approach?

scientific article published on 26 May 2006

SH2D4A is frequently downregulated in hepatocellular carcinoma and cirrhotic nodules

scientific article published on 3 December 2013

Salmonella enterocolitis and hemorrhagic shock

scientific article published on 23 April 2007

Screening for ALK in non-small cell lung carcinomas: 5A4 and D5F3 antibodies perform equally well, but combined use with FISH is recommended

scientific article published on 21 May 2015

Silencing of the SEC62 gene inhibits migratory and invasive potential of various tumor cells ⬇️

scientific article published on May 15, 2011

Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours

scientific article

Systematic assessment of the prognostic impact of membranous CD44v6 protein expression in colorectal cancer

scientific article published on 01 November 2009

Tenascin-W, a new marker of cancer stroma, is elevated in sera of colon and breast cancer patients

scientific article published on 01 June 2008

The HOX gene network in hepatocellular carcinoma.

scientific article published on 30 May 2011

The RNA-binding protein RBM3 is required for cell proliferation and protects against serum deprivation-induced cell death.

scientific article

The clinical impact of p16 status in fine-needle aspirates of cervical lymph node metastasis of head and neck squamous cell carcinomas

scientific article published on 16 May 2012

The homeobox intestinal differentiation factor CDX2 is selectively expressed in gastrointestinal adenocarcinomas

scientific article published in November 2004

The loss of the CBX7 gene expression represents an adverse prognostic marker for survival of colon carcinoma patients.

scientific article

Transcriptional regulation of vascular bone morphogenetic protein by endothelin receptors in early autoimmune diabetes mellitus

scientific article

Tumor infiltration by FcγRIII (CD16)+ myeloid cells is associated with improved survival in patients with colorectal carcinoma.

scientific article

V600E BRAF mutations are alternative early molecular events in a subset of KIT/PDGFRA wild-type gastrointestinal stromal tumours.

scientific article

VEGFA gene locus (6p12) amplification identifies a small but highly aggressive subgroup of colorectal cancer [corrected] patients.

scientific article

VEGFA gene locus analysis across 80 human tumour types reveals gene amplification in several neoplastic entities

scientific article published on 11 October 2013

YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors

scientific article published on 14 July 2015

p16 expression in oropharyngeal cancer: its impact on staging and prognosis compared with the conventional clinical staging parameters

scientific article

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