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List of works by Rafael Solana

(Challenges of vaccination in older people. Can we circumvent immunosenescence?).

scientific article

Adaptive Memory of Human NK-like CD8+ T-Cells to Aging, and Viral and Tumor Antigens

scientific article published on 19 December 2016

Age-dependent association between low frequency of CD27/CD28 expression on pp65 CD8+ T cells and cytomegalovirus replication after transplantation.

scientific article published on 05 August 2009

Age-related alterations to natural killer cell function

scientific article published on 01 January 2000

Aging and Innate Immunity

Aging of the immune system as a prognostic factor for human longevity

scientific article published on April 2008

Alterations in CFU-GM growth in preleukaemic and leukaemic AKR/J mice

scientific article published in January 1985

Analysis of the mechanisms involved in NK resistance induced by a new tumor factor NK-RIF.

scientific article published on October 1990

Are cancer and ageing different sides of the same coin? Conference on Cancer and Ageing

scientific article published on 8 February 2008

Association of the KIR3DS1*013 and KIR3DL1*004 alleles with susceptibility to ankylosing spondylitis.

scientific article published in April 2010

Basic biology and clinical impact of immunosenescence

scientific article published in January 2002

CD45RA expression on HCMV-specific effector memory CD8+ T cells is associated with the duration and intensity of HCMV replication after transplantation

scientific article published on 31 July 2010

CD69 is a stimulatory receptor for natural killer cell and its cytotoxic effect is blocked by CD94 inhibitory receptor

scientific article published on 01 May 1999

CD8 T cells expressing NK associated receptors are increased in melanoma patients and display an effector phenotype

scientific article published on 12 May 2005

CMV and Immunosenescence: from basics to clinics

scientific article published on 31 October 2012

CMV induces expansion of highly polyfunctional CD4+ T cell subset coexpressing CD57 and CD154.

scientific article published on 26 August 2016

CMV latent infection improves CD8+ T response to SEB due to expansion of polyfunctional CD57+ cells in young individuals

scientific article

Calcitriol effect on natural killer cells from hemodialyzed and normal subjects

scientific article published on 01 February 1995

Cell mediated immunity in ageing ⬇️

scientific article published on January 1, 1991

Cellular redox status influences both cytotoxic and NF-kappa B activation in natural killer cells

scientific article published on 01 March 1997

Changes in lymphoblastic transformation in preleukemic AKR/J mice

scientific article published on 01 January 1982

Changes in the expression of HLA-class II antigens on peripheral blood monocytes from aged humans

scientific article published on 01 March 1990

Characterization of the DNAM-1, TIGIT and TACTILE Axis on Circulating NK, NKT-Like and T Cell Subsets in Patients with Acute Myeloid Leukemia

scientific article published on 05 August 2020

Clinical factors influencing phenotype of HCMV-specific CD8+ T cells and HCMV-induced interferon-gamma production after allogeneic stem cells transplantation

scientific article published on 2 February 2013

Correlation of effector function with phenotype and cell division after in vitro differentiation of naive MART-1-specific CD8+ T cells

scientific article

Current progress in NK cell biology and NK cell-based cancer immunotherapy

scientific article published on 04 March 2020

Cytokine profiles in acute myeloid leukemia patients at diagnosis: survival is inversely correlated with IL-6 and directly correlated with IL-10 levels

scientific article published on 26 January 2013

Cytomegalovirus infection: a driving force in human T cell immunosenescence

scientific article published on October 2007

DNAM-1 and the TIGIT/PVRIG/TACTILE Axis: Novel Immune Checkpoints for Natural Killer Cell-Based Cancer Immunotherapy

scientific article published on 23 June 2019

Decreased expression of DNAM-1 on NK cells from acute myeloid leukemia patients

scientific article published on 08 March 2011

Decreased frequency and proliferative response of invariant Vα24Vβ11 natural killer T (iNKT) cells in healthy elderly

scientific article published on 01 October 2006

Depressed lymphoproliferative response in mixed leukocyte reaction after Mis-locus alloimmunization

scientific article published on 01 March 1984

Differences in GM-CSF production from mouse peripheral blood and spleen cells stimulated by different lectins

scientific article published on 01 June 1983

Differential Effect of Cytomegalovirus Infection with Age on the Expression of CD57, CD300a, and CD161 on T-Cell Subpopulations

scientific article

Differential expression of HLA-DR and HLA-DQ antigens on normal cells of the myelomonocytic lineage

scientific article published on 01 November 1985

Downregulation of Fc gamma receptor IIIA alpha (CD16-II) on natural killer cells induced by anti-CD16 mAb is independent of protein tyrosine kinases and protein kinase C

scientific article published on 01 October 1994

Editorial: NK Cell-Based Cancer Immunotherapy

scientific article published on 27 June 2016

Effect of Age on NK Cell Compartment in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors

scientific article published on 08 November 2018

Effect of CMV and Aging on the Differential Expression of CD300a, CD161, T-bet, and Eomes on NK Cell Subsets.

scientific article

Effect of Cytomegalovirus (CMV) and Ageing on T-Bet and Eomes Expression on T-Cell Subsets

scientific article published on 29 June 2017

Effect of Fiblaferon-L on the human immune system

scientific article published on 01 January 1984

Effect of a new synthetic C-nucleoside (EDTO) on cell proliferation.

scientific article published on May 1984

Effect of a new synthetic cyclic-nucleoside on cell proliferation

scientific article published on January 1983

Effect of age and CMV on NK cell subpopulations

scientific article published on 17 January 2014

Effect of age and latent CMV infection on CD8+ CD56+ T cells (NKT-like) frequency and functionality

scientific article

Effect of ageing on CMV-specific CD8 T cells from CMV seropositive healthy donors

scientific article published on 28 August 2009

Effect of cyproheptadine on gastric secretion in rats

scientific article published on 01 January 1983

Effect of exogenous serotonin on intragastric pH and its influence on serum gastrin levels in rats

scientific article published on December 1, 1979

Effect of phorbol ester TPA on macrophage metabolic activity

scientific article published in February 1984

Expression of HLA molecules on cells from fresh explants of human digestive tract cancer

scientific article published on 01 April 1986

Expression of NK-associated receptors on cytotoxic T cells from melanoma patients: a two-edged sword?

scientific article published on 4 May 2004

Expression of NKp30, NKp46 and DNAM-1 activating receptors on resting and IL-2 activated NK cells from healthy donors according to CMV-serostatus and age.

scientific article

Expression of adhesion molecules and ligands for activating and costimulatory receptors involved in cell-mediated cytotoxicity in a large panel of human melanoma cell lines

scientific article published on 04 March 2009

Expression of killer inhibitory receptors on cytotoxic cells from HIV-1-infected individuals

scientific article published in March 1999

Factors related to the development of CMV-specific CD8+ T cell response in CMV-seropositive solid organ transplant candidates.

scientific article published on 3 February 2015

Flow Cytometry Analysis of NK Cell Phenotype and Function in Aging

scientific article published on January 2015

Functional Implications of HNK-1 Expression on Invasive Behaviour of Melanoma Cells

scientific article published on 19 September 2008

HAART induces the expression of HLA-G on peripheral monocytes in HIV-1 infected individuals.

scientific article published in November 2003

HLA antigen familial study in complete Behçet's syndrome affecting three sisters

scientific article

HLA expression in basal cell carcinomas.

scientific article published on January 1991

HLA molecule expression in cutaneous squamous cell carcinomas: an immunopathological study and clinical-immunohistopathological correlations

scientific article published on 01 April 1993

HLA-B2702 (77-83/83-77) peptide binds to beta-tubulin on human NK cells and blocks their cytotoxic capacity

scientific article

HLA-DQ molecular heterogeneity in HLA-DR4-Dw4 consanguineous cell lines

scientific article

Histocompatibility antigens and natural killer susceptibility

scientific article published on January 1, 1992

Human CD4+ T cell clone longevity in tissue culture: lack of influence of donor age or cell origin ⬇️

scientific article published on January 1, 2002

Human NK cells in acute myeloid leukaemia patients: analysis of NK cell-activating receptors and their ligands

scientific article published on 05 June 2011

Human cytomegalovirus infection and T cell immunosenescence: a mini review

scientific article

Human immunosenescence: is it infectious?

scientific article

IFNγ⁻TNFα⁻IL2⁻MIP1α⁻CD107a⁺PRF1⁺ CD8 pp65-Specific T-Cell Response Is Independently Associated With Time to Death in Elderly Humans

scientific article

IL-2 increased RANTES production and CD25 expression in cultured PBMCs only from antiretroviral treated HIV-1+ patients with detectable viral loads

scientific article published on 03 February 2006

Identification of a tumour factor inducing resistance to NK cell lysis

scientific article published on 01 March 1989

Immunity, ageing and cancer

scientific article published on 24 September 2008

Immunoageing - the cause or effect of morbidity

scientific article published on 01 July 2001

Immunologic effects of vitamin D

scientific article published on 01 September 1989

Immunological biomarkers of ageing in man: changes in both innate and adaptive immunity are associated with health and longevity

scientific article published on October 2006

Immunosenescence

scientific article published on 01 November 1997

Immunosenescence and vaccine failure in the elderly

scientific article published on June 2009

Immunosenescence of Natural Killer Cells, Inflammation, and Alzheimer's Disease

scholarly article by Corona Solana et al published 2018 in International journal of Alzheimer's disease

Immunosenescence of human natural killer cells

scientific article published on 11 May 2011

Immunosenescence: Implications for response to infection and vaccination in older people

scientific article published on 18 May 2015

Immunosenescence: limitations of natural killer cell-based cancer immunotherapy.

scientific article published on 16 August 2016

Impact of Cytomegalovirus on Early Immunosenescence of CD8+ T Lymphocytes After Solid Organ Transplantation ⬇️

scientific article published on 02 May 2012

Impact of Preformed Donor-Specific Anti-Human Leukocyte Antigen Antibody C1q-Binding Ability on Kidney Allograft Outcome.

scientific article published on 31 October 2017

Impact of age and cytomegalovirus on CD8+ T-cell compartment remodeling after solid organ transplantation: A one-year follow-up study

scientific article

Impact of aging on innate immunity

scientific article published on 01 December 1998

Impaired capacity of the macrophages of newborn mice for T-lymphocyte activation by phytohemagglutinin

scientific article published on 01 March 1982

Impaired response of HIV type 1-specific CD8(+) cells from antiretroviral-treated patients

scientific article published on 01 October 2007

In Vitro Culture with Interleukin-15 Leads to Expression of Activating Receptors and Recovery of Natural Killer Cell Function in Acute Myeloid Leukemia Patients

scientific article published on 7 August 2017

Inhibition of CD28-mediated natural cytotoxicity by KIR2DL2 does not require p56(lck) in the NK cell line YT-Indy

scientific article

Innate immunosenescence: effect of aging on cells and receptors of the innate immune system in humans

scientific article published on 04 May 2012

Isolation of a novel tumor protein that induces resistance to natural killer cell lysis.

scientific article published on November 1990

Kinetics and characteristics of murine macrophage-lymphocyte interaction in presence of PHA: appearance of multinucleated giant cells in vitro

scientific article published on 01 September 1983

Lifespans of T lymphocytes.

scientific article published on October 1996

Longevity in vitro of human CD4+ T helper cell clones derived from young donors and elderly donors, or from progenitor cells: age-associated differences in cell surface molecule expression and cytokine secretion

scientific article

Lymphocyte activation in response to melanoma: interaction of NK-associated receptors and their ligands

scientific article

MHC antigens in NK cell recognition and lysis

scientific article

MHC class I antigen expression is inversely related with tumor malignancy and ras oncogene product (p21ras) levels in human breast tumors

scientific article published on 01 January 1992

MHC class I expression on human tumour cells and their susceptibility to NK lysis

scientific article published on 01 August 1989

Macrophage and lymphocyte antibody-dependent cellular cytotoxicity in spontaneous leukemogenesis of AKR/J mice

scientific article published on 01 January 1989

Mechanisms involved in NK resistance induced by interferon-gamma.

scientific article

Modulation of NK cells with checkpoint inhibitors in the context of cancer immunotherapy

scientific article published on 05 April 2019

Modulation of the expression of HLA class II antigens by gamma interferon and phorbol ester TPA on myeloid leukaemic cell lines

scientific article published on 01 April 1986

Molecular and cellular basis of immunosenescence

scientific article published on 01 May 1998

Multifunctional cytomegalovirus (CMV)-specific CD8(+) T cells are not restricted by telomere-related senescence in young or old adults.

scientific article

NK cell recognition and killing of melanoma cells is controlled by multiple activating receptor-ligand interactions

scientific article published on 11 May 2011

NK cells in healthy aging and age-associated diseases

scientific article

NK phenotypic markers and IL2 response in NK cells from elderly people

scientific article

NK-associated receptors on CD8 T cells from treatment-naive HIV-infected individuals: defective expression of CD56

scientific article published on 01 January 2002

Natural Killer Cell Recognition of Melanoma: New Clues for a More Effective Immunotherapy

scientific article

Natural killer cell immunosenescence in acute myeloid leukaemia patients: new targets for immunotherapeutic strategies?

scientific article published on 10 June 2015

Natural killer susceptibility is independent of HLA class I antigen expression on cell lines obtained from human solid tumors.

scientific article

Natural killer susceptibility of brain tumor cell lines inversely correlates with the degree of cell differentiation and not with the level of human histocompatibility antigen expression

scientific article

New advances in CMV and immunosenescence

scientific article

PHA reactivity of spontaneous AKR lymphomas: absolute macrophage requirement.

scientific article published in September 1984

Polymorphisms of HLA-A, -B, -Cw and DRB1 antigens in Moroccan patients with ankylosing spondylitis and a comparison of clinical features with frequencies of HLA-B*27.

scientific article

Possible central antisecretory action of exogenous serotonin in rats

scientific article published on March 1980

Possible mechanism of stimulation of gastrin secretion by exogenous serotonin in rats

scientific article published on 01 September 1980

Pre-transplant thymic function is associated with the risk of cytomegalovirus disease after solid organ transplantation.

scientific article published on 14 January 2015

Pretransplant interferon-γ secretion by CMV-specific CD8+ T cells informs the risk of CMV replication after transplantation.

scientific article published on 11 January 2013

Prevention strategies differentially modulate the impact of cytomegalovirus replication on CD8(+) T-cell differentiation in high-risk solid organ transplant patients

scientific article published on July 2016

Proinflammatory status influences NK cells subsets in the elderly

scientific article published on 3 July 2014

Regulation of CD69 expression on human natural killer cells: differential involvement of protein kinase C and protein tyrosine kinases

scientific article published on 01 May 1993

Report from the second cytomegalovirus and immunosenescence workshop

scientific article published on 28 October 2011

Requirement of macrophage metabolic activity for T-lymphocyte activation

scientific article published on 01 March 1982

Response to "Influence of Age and HLA Alleles on the CMV-Specific Cell-Mediated Immunity Among CMV-Seropositive Kidney Transplant Candidates".

scientific article published on 2 July 2015

Role of defective thymic function in onset of ganciclovir-resistant cytomegalovirus after cord blood transplantation

scientific article published on 10 October 2012

Role of the carboxy-termini of tubulin on its chaperone-like activity

scientific article published in August 2001

Selective depletion of CD56(dim) NK cell subsets and maintenance of CD56(bright) NK cells in treatment-naive HIV-1-seropositive individuals

scientific article published on 01 May 2002

Shaping of NK cell subsets by aging

scientific article published on 08 May 2014

Soluble suppressor of T cell proliferation in primary in vitro response to murine minor histocompatibility antigens

scientific article published on 01 September 1984

T cells and aging

scientific article published on 15 January 1998

T cells and aging, January 2002 update.

scientific article

The B-ring substituent at C-7 of colchicine and the alpha-C-terminus of tubulin communicate through the "tail-body" interaction

scientific article published in November 2004

The T cell in the ageing individual

scientific article published on February 1997

The effect of calcitriol on natural killer cell activity in hemodialyzed patients.

scientific article published in January 1989

Threonine 80 on HLA-B27 confers protection against lysis by a group of natural killer clones

scientific article published on 01 August 1996

Vα24+ NKT cells are decreased in elderly humans

scientific article published on 01 January 2002

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