List of works - José I Borrell

2-Methoxy-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitriles: versatile starting materials for the synthesis of libraries with diverse heterocyclic scaffolds

scientific article

4-Amino-2-arylamino-6-(2,6-dichlorophenyl)-pyrido[2,3-d]pyrimidin-7-(8H)-ones as BCR kinase inhibitors for B lymphoid malignancies.

scientific article

A captured room temperature stable Wheland intermediate as a key structure for the orthogonal decoration of 4-amino-pyrido[2,3-d]pyrimidin-7(8H)-ones

scientific article published on 01 October 2020

A convenient synthesis of 13N-labelled azo compounds: a new route for the preparation of amyloid imaging PET probes.

scientific article published on 15 September 2010

A diversity oriented, microwave assisted synthesis of N-substituted 2-hydro-4-amino-pyrido[2,3-d]pyrimidin-7(8H)-ones

scientific article published on 27 November 2008

A diversity-oriented synthesis of 3-(2-amino-1,6-dihydro-6-oxo-pyrimidin-5-yl)propanoic esters

scientific article published on 12 November 2010

A new and practical method for the synthesis of 6-aryl-5,6-dihydropyrido[2,3-[Formula: see text]]pyrimidine-4,7(3[Formula: see text],8[Formula: see text])-diones.

scientific article published on 26 May 2013

A one-pot microwave-assisted synthesis of pyrido[2,3-d]pyrimidines

scientific article published in January 2003

A regiospecific synthesis of both positional isomers of 4,6-disubstituted 2-dicyanomethylene-1, 2-dihydropyridin-3-carbonitriles

scientific article published on 14 January 2010

APIF: a new interaction fingerprint based on atom pairs and its application to virtual screening.

scientific article published in May 2009

An unusual Michael addition of 3,3-dimethoxypropanenitrile to 2-aryl acrylates: a convenient route to 4-unsubstituted 5,6-dihydropyrido[2,3-d]pyrimidines

scientific article published in January 2010

C4-C5 fused pyrazol-3-amines: when the degree of unsaturation and electronic characteristics of the fused ring controls regioselectivity in Ullmann and acylation reactions

scientific article published on 25 June 2020

Cell-integral-diversity criterion: a proposal for minimizing cluster artifact in cell-based selections

scientific article

Clustering and classifying diverse HIV entry inhibitors using a novel consensus shape-based virtual screening approach: further evidence for multiple binding sites within the CCR5 extracellular pocket.

scientific article published in November 2008

Comparison of ligand-based and receptor-based virtual screening of HIV entry inhibitors for the CXCR4 and CCR5 receptors using 3D ligand shape matching and ligand-receptor docking

scientific article

Design and analysis of a combinatorial library of HEPT analogues: comparison of selection methodologies and inspection of the actually covered chemical space

scientific article

Design, synthesis and biological activity of acyl substituted 3-amino-5-methyl-1,4,5,7-tetrahydropyrazolo[3,4-b]pyridin-6-ones as potential hypnotic drugs

scientific article published on 10 August 2005

Diethyl 2,7-dibromo-4H,5H- thieno[3,2-b:4,5-b']dipyrrole-3,6- dicarboxylate: a key intermediate for a diversity oriented synthesis of 2,7,12,17-tetraarylporphycenes

scientific article published on 01 March 2006

Discovery of novel HIV entry inhibitors for the CXCR4 receptor by prospective virtual screening.

scientific article

Discovery of novel non-cyclam polynitrogenated CXCR4 coreceptor inhibitors

scientific article

Diverse combinatorial design, synthesis and in vitro evaluation of new HEPT analogues as potential non-nucleoside HIV-1 reverse transcription inhibitors

scientific article

Effect of aza substitution on the photophysical and electrochemical properties of porphycenes: Characterization of the near-IR-absorbing photosensitizers 2,7,12,17-tetrakis(p-substituted phenyl)-3,6,13,16-tetraazaporphycenes.

scientific article

Efficient system for the preparation of [13N]labeled nitrosamines

scientific article published on 21 February 2009

Impact of the CXCR4 structure on docking-based virtual screening of HIV entry inhibitors.

scientific article

Improving VEGFR-2 Docking-Based Screening by Pharmacophore Postfiltering and Similarity Search Postprocessing ⬇️

scientific article published on March 18, 2011

Noncyclam tetraamines inhibit CXC chemokine receptor type 4 and target glioma-initiating cells

scientific article published on 29 August 2012

Novel monocyclam derivatives as HIV entry inhibitors: Design, synthesis, anti-HIV evaluation, and their interaction with the CXCR4 co-receptor.

scientific article

One-pot synthesis of substituted 2,2'-bipyrroles. A straightforward route to aryl porphycenes

scientific article published on 01 January 2009

Photochemical production and characterisation of the radical ions of tetraphenylporphycenes

scientific article published on 08 February 2006

Porphycenes: facts and prospects in photodynamic therapy of cancer.

scientific article published on January 2007

Preparative-scale synthesis of two metabolites isolated from soil treated with zoxium fungicide and kerb herbicide

scientific article published in January 2002

Pyrido[2,3-d]pyrimidin-7(8H)-ones: Synthesis and Biomedical Applications

scientific article published on 16 November 2019

Selective hydrolysis of 2,4-diaminopyrimidine systems: a theoretical and experimental insight into an old rule

scientific article

Solid phase vs. solution phase differential behavior: formation of a salicylate structure from a malondialdehyde moiety

scientific article published on 01 January 2000

Solid-phase synthesis of 2-substituted 4-amino-7-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidines: an example of cyclization-assisted cleavage.

scientific article

Structure-based virtual screening of FGFR inhibitors: cross-decoys and induced-fit effect.

scientific article

Studying the binding interactions of allosteric agonists and antagonists of the CXCR4 receptor.

scientific article

Synthesis and biological activity of 4-amino-7-oxo-substituted analogues of 5-deaza-5,6,7,8-tetrahydrofolic acid and 5,10-dideaza-5, 6,7,8-tetrahydrofolic acid

scientific article published on 01 August 1998

Synthesis and biological activity of 7-oxo substituted analogues of 5-deaza-5,6,7,8-tetrahydrofolic acid (5-DATHF) and 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF).

scientific article

Synthesis of 2-arylamino substituted 5,6-dihydropyrido[2,3-d]pyrimidine-7(8H)-ones from arylguanidines

scientific article published on 10 October 2012

Two-photon absorption in tetraphenylporphycenes: are porphycenes better candidates than porphyrins for providing optimal optical properties for two-photon photodynamic therapy?

scientific article published on 31 March 2007

List of works by José I Borrell

2-Methoxy-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitriles: versatile starting materials for the synthesis of libraries with diverse heterocyclic scaffolds

4-Amino-2-arylamino-6-(2,6-dichlorophenyl)-pyrido[2,3-d]pyrimidin-7-(8H)-ones as BCR kinase inhibitors for B lymphoid malignancies.

A captured room temperature stable Wheland intermediate as a key structure for the orthogonal decoration of 4-amino-pyrido[2,3-d]pyrimidin-7(8H)-ones

A convenient synthesis of 13N-labelled azo compounds: a new route for the preparation of amyloid imaging PET probes.

A diversity oriented, microwave assisted synthesis of N-substituted 2-hydro-4-amino-pyrido[2,3-d]pyrimidin-7(8H)-ones

A diversity-oriented synthesis of 3-(2-amino-1,6-dihydro-6-oxo-pyrimidin-5-yl)propanoic esters

A new and practical method for the synthesis of 6-aryl-5,6-dihydropyrido[2,3-[Formula: see text]]pyrimidine-4,7(3[Formula: see text],8[Formula: see text])-diones.

A one-pot microwave-assisted synthesis of pyrido[2,3-d]pyrimidines

A regiospecific synthesis of both positional isomers of 4,6-disubstituted 2-dicyanomethylene-1, 2-dihydropyridin-3-carbonitriles

APIF: a new interaction fingerprint based on atom pairs and its application to virtual screening.

An unusual Michael addition of 3,3-dimethoxypropanenitrile to 2-aryl acrylates: a convenient route to 4-unsubstituted 5,6-dihydropyrido[2,3-d]pyrimidines

C4-C5 fused pyrazol-3-amines: when the degree of unsaturation and electronic characteristics of the fused ring controls regioselectivity in Ullmann and acylation reactions

Cell-integral-diversity criterion: a proposal for minimizing cluster artifact in cell-based selections

Clustering and classifying diverse HIV entry inhibitors using a novel consensus shape-based virtual screening approach: further evidence for multiple binding sites within the CCR5 extracellular pocket.

Comparison of ligand-based and receptor-based virtual screening of HIV entry inhibitors for the CXCR4 and CCR5 receptors using 3D ligand shape matching and ligand-receptor docking

Design and analysis of a combinatorial library of HEPT analogues: comparison of selection methodologies and inspection of the actually covered chemical space

Design, synthesis and biological activity of acyl substituted 3-amino-5-methyl-1,4,5,7-tetrahydropyrazolo[3,4-b]pyridin-6-ones as potential hypnotic drugs

Diethyl 2,7-dibromo-4H,5H- thieno[3,2-b:4,5-b']dipyrrole-3,6- dicarboxylate: a key intermediate for a diversity oriented synthesis of 2,7,12,17-tetraarylporphycenes

Discovery of novel HIV entry inhibitors for the CXCR4 receptor by prospective virtual screening.

Discovery of novel non-cyclam polynitrogenated CXCR4 coreceptor inhibitors

Diverse combinatorial design, synthesis and in vitro evaluation of new HEPT analogues as potential non-nucleoside HIV-1 reverse transcription inhibitors

Effect of aza substitution on the photophysical and electrochemical properties of porphycenes: Characterization of the near-IR-absorbing photosensitizers 2,7,12,17-tetrakis(p-substituted phenyl)-3,6,13,16-tetraazaporphycenes.

Efficient system for the preparation of [13N]labeled nitrosamines

Impact of the CXCR4 structure on docking-based virtual screening of HIV entry inhibitors.

Improving VEGFR-2 Docking-Based Screening by Pharmacophore Postfiltering and Similarity Search Postprocessing ⬇️

Noncyclam tetraamines inhibit CXC chemokine receptor type 4 and target glioma-initiating cells

Novel monocyclam derivatives as HIV entry inhibitors: Design, synthesis, anti-HIV evaluation, and their interaction with the CXCR4 co-receptor.

One-pot synthesis of substituted 2,2'-bipyrroles. A straightforward route to aryl porphycenes

Photochemical production and characterisation of the radical ions of tetraphenylporphycenes

Porphycenes: facts and prospects in photodynamic therapy of cancer.

Preparative-scale synthesis of two metabolites isolated from soil treated with zoxium fungicide and kerb herbicide

Pyrido[2,3-d]pyrimidin-7(8H)-ones: Synthesis and Biomedical Applications

Selective hydrolysis of 2,4-diaminopyrimidine systems: a theoretical and experimental insight into an old rule

Solid phase vs. solution phase differential behavior: formation of a salicylate structure from a malondialdehyde moiety

Solid-phase synthesis of 2-substituted 4-amino-7-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidines: an example of cyclization-assisted cleavage.

Structure-based virtual screening of FGFR inhibitors: cross-decoys and induced-fit effect.

Studying the binding interactions of allosteric agonists and antagonists of the CXCR4 receptor.

Synthesis and biological activity of 4-amino-7-oxo-substituted analogues of 5-deaza-5,6,7,8-tetrahydrofolic acid and 5,10-dideaza-5, 6,7,8-tetrahydrofolic acid

Synthesis and biological activity of 7-oxo substituted analogues of 5-deaza-5,6,7,8-tetrahydrofolic acid (5-DATHF) and 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF).

Synthesis of 2-arylamino substituted 5,6-dihydropyrido[2,3-d]pyrimidine-7(8H)-ones from arylguanidines

Two-photon absorption in tetraphenylporphycenes: are porphycenes better candidates than porphyrins for providing optimal optical properties for two-photon photodynamic therapy?