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List of works by Malin Flodström-Tullberg

A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes

scientific article published on 18 November 2017

A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defence.

scientific article published on 9 September 2017

A comparative study of the effect of UV and formalin inactivation on the stability and immunogenicity of a Coxsackievirus B1 vaccine

scientific article published on 27 August 2019

A critical role for inducible nitric oxide synthase in host survival following coxsackievirus B4 infection.

scientific article published in March 2001

A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates

scientific article published on 06 May 2020

A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses.

scientific article published on 8 January 2018

A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models.

scientific article published on 5 November 2014

Alloreactivity but Failure to Reject Human Islet Transplants by Humanized Balb/c/Rag2−/−gc−/−Mice

scientific article published on 01 February 2010

An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets

scientific article published on 21 December 2016

Antibody Responses against Enterovirus Proteases are Potential Markers for an Acute Infection

scientific article published on 09 January 2020

Application of bioinformatics in probe design enables detection of enteroviruses on different taxonomic levels by advanced in situ hybridization technology

scientific article published on 23 June 2015

B7-2 (CD86) controls the priming of autoreactive CD4 T cell response against pancreatic islets

article

Beta-cell specific expression of suppressor of cytokine signaling-1 (SOCS-1) delays islet allograft rejection by down-regulating Interferon Regulatory Factor-1 (IRF-1) signaling

scientific article published on 01 December 2010

CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells

scientific article

CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells

scientific article

Co-transplantation of stromal cells interferes with the rejection of allogeneic islet grafts

scientific article

Composition and functionality of the intrahepatic innate lymphoid cell-compartment in human nonfibrotic and fibrotic livers

scientific article published on 14 June 2017

Coxsackievirus B Persistence Modifies the Proteome and the Secretome of Pancreatic Ductal Cells

scientific article published on 29 July 2019

Coxsackievirus counters the host innate immune response by blocking type III interferon expression.

scientific article

Cystic fibrosis bronchial epithelial cells have impaired ability to activate vitamin D.

scientific article published on 10 February 2016

Cytokines activate the nuclear factor kappa B (NF-kappa B) and induce nitric oxide production in human pancreatic islets

article

Defective exocytosis and processing of insulin in a cystic fibrosis mouse model

scientific article published on 01 February 2019

Defining the proteolytic landscape during enterovirus infection

scientific article published on 30 September 2020

Depletion of IL-2 receptor β-positive cells protects from diabetes in non-obese diabetic mice.

scientific article published on 5 August 2015

Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? Reply to Hansson SF, Korsgren S, Pontén F et al [letter].

scientific article published on 16 January 2014

Diabetogenic potential of human pathogens uncovered in experimentally permissive beta-cells.

scientific article published in August 2003

Differences in suppressor of cytokine signaling-1 (SOCS-1) expressing islet allograft destruction in normal BALB/c and spontaneously-diabetic NOD recipient mice.

scientific article published in May 2005

Distinct phenotype and function of NK cells in the pancreas of nonobese diabetic mice.

scientific article

Ebselen and cytokine-induced nitric oxide synthase expression in insulin-producing cells.

scientific article published on December 1996

Enteroviral proteases: structure, host interactions and pathogenicity.

scientific article published on 4 May 2016

Enterovirus Exposure Uniquely Discriminates Type 1 Diabetes Patients with a Homozygous from a Heterozygous Melanoma Differentiation-Associated Protein 5/Interferon Induced with Helicase C Domain 1 A946T Genotype

scientific article published on 2 August 2016

Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein, VP1, in human pancreas.

scientific article published on 5 November 2013

Expression of Intestinal and Lung Alkaline Sphingomyelinase and Neutral Ceramidase in Cystic Fibrosis F508del Transgenic Mice

scientific article published on 01 November 2008

Expression of the citrulline-nitric oxide cycle in rodent and human pancreatic beta-cells: induction of argininosuccinate synthetase by cytokines

scientific article published on 01 August 1995

Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education

article

Formalin treatment increases the stability and immunogenicity of coxsackievirus B1 VLP vaccine

scientific article published on 03 September 2019

Genetic and Environmental Interaction in Type 1 Diabetes: a Relationship Between Genetic Risk Alleles and Molecular Traits of Enterovirus Infection?

scientific article published on 10 August 2019

Immunology in the clinic review series; focus on type 1 diabetes and viruses: the innate immune response to enteroviruses and its possible role in regulating type 1 diabetes.

scientific article published on April 2012

Induction of an antiviral state and attenuated coxsackievirus replication in type III interferon-treated primary human pancreatic islets

scientific article published on May 2013

Interferons induce an antiviral state in human pancreatic islet cells

scientific article published on 08 June 2007

Interleukin 1beta increases arginine accumulation and activates the citrulline-NO cycle in rat pancreatic beta cells

scientific article published on 01 June 1999

Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence. Reply to Skog O, Klingel K, Roivainen M et al [letter]

scientific article published on 23 April 2019

Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus

scholarly article

Mechanisms of Defective Glucose-Induced Insulin Release in Human Pancreatic Islets Transplanted to Diabetic Nude Mice1

scientific article published on 01 August 1997

Natural killer cells in human autoimmunity

scientific article

New Coxsackievirus 2Apro and 3Cpro protease antibodies for virus detection and discovery of pathogenic mechanisms.

scientific article published on 6 February 2018

Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling

scientific article

Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model.

scientific article published on June 2017

Previous maternal infection protects offspring from enterovirus infection and prevents experimental diabetes development in mice.

scientific article published on 24 January 2013

Protection against type 1 diabetes upon Coxsackievirus B4 infection and iNKT-cell stimulation: role of suppressive macrophages

scientific article published on 26 July 2013

Pyrrolidine dithiocarbamate prevents IL-1-induced nitric oxide synthase mRNA, but not superoxide dismutase mRNA, in insulin producing cells.

scientific article published on May 1995

RNase L and double-stranded RNA-dependent protein kinase exert complementary roles in islet cell defense during coxsackievirus infection.

scientific article published in February 2005

Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes

scientific article published on 23 January 2019

Recent acquisitions on the genetic basis of autoimmune disease

scientific article published on May 2008

Role of the citrulline-nitric oxide cycle in the functional response of adult human and rodent pancreatic islets to cytokines

article

SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high-fat-diet-fed mice

scientific article published on 04 May 2012

Severely Impaired Control of Bacterial Infections in a Patient With Cystic Fibrosis Defective in Mucosal-Associated Invariant T Cells.

scientific article

Short-term CFTR inhibition reduces islet area in C57BL/6 mice

scientific article published on 02 August 2019

Strong attraction may be dangerous: parameters for the development of long term commitment.

scientific article

Structural Insight into CVB3-VLP Non-Adjuvanted Vaccine

scientific article published on 24 August 2020

Target cell defense prevents the development of diabetes after viral infection.

scientific article published on 4 March 2002

Target cell expression of suppressor of cytokine signaling-1 prevents diabetes in the NOD mouse.

scientific article published in November 2003

The TheraCyte™ Device Protects against Islet Allograft Rejection in Immunized Hosts

scientific article published on 03 October 2012

The natural killer cell -- friend or foe in autoimmune disease?

scientific article

The stromal cell-derived factor-1alpha/CXCR4 ligand-receptor axis is critical for progenitor survival and migration in the pancreas

scientific article

The target cell response to cytokines governs the autoreactive T cell repertoire in the pancreas of NOD mice.

scientific article

The target tissue in autoimmunity--an influential niche

scientific article published on March 2007

Type III interferons are expressed by Coxsackievirus-infected human primary hepatocytes and regulate hepatocyte permissiveness to infection.

scientific article published on September 2014

Viral infections: their elusive role in regulating susceptibility to autoimmune disease

scientific article

Vitamin D treatment modulates immune activation in cystic fibrosis.

scientific article published on 3 May 2017