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List of works by Choon Kiat Ong

2-Chloroethyl-3-sarcosinamide-1-nitrosourea (SarCNU) exhibits p53-dependent and -independent antiproliferative activity in human nasopharyngeal carcinoma cells in vitro and in vivo.

scientific article

A clinicohaematological prognostic model for nasal-type natural killer/T-cell lymphoma: A multicenter study

scientific article published on 18 October 2019

An Optimised Protocol Harnessing Laser Capture Microdissection for Transcriptomic Analysis on Matched Primary and Metastatic Colorectal Tumours

scientific article published on 20 January 2020

Application of an ex-vivo drug sensitivity platform towards achieving complete remission in a refractory T-cell lymphoma

scientific article published on 27 January 2020

Complications of pancreatic surgery

scientific article published on January 2005

EBV-associated primary nodal T/NK-cell lymphoma shows distinct molecular signature and copy number changes.

scientific article published on 2 November 2017

Effect of Ang-2-VEGF-A Bispecific Antibody in Renal Cell Carcinoma

scientific article published on 26 June 2015

Evaluation of the PIK3 pathway in peripheral T-cell lymphoma and NK/T-cell lymphoma

scientific article published on 31 January 2020

Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers

scientific article published on 3 November 2013

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

scientific article

Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma.

scientific article

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

scientific article published on 01 May 2012

Exome-wide Sequencing Shows Low Mutation Rates and Identifies Novel Mutated Genes in Seminomas

scientific article published on 14 January 2015

Expression of the PTTG1 oncogene is associated with aggressive clear cell renal cell carcinoma

scientific article

First somatic mutation of E2F1 in a critical DNA binding residue discovered in well-differentiated papillary mesothelioma of the peritoneum.

scientific article published on 28 September 2011

Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencing

scientific article

Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma

scientific article published on 19 February 2019

Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study in multiple populations

scientific article published on 23 December 2019

Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study.

scientific article published on 25 July 2016

Genome-wide mutational signatures of aristolochic acid and its application as a screening tool

scientific article

Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes

scientific article published on 23 May 2019

Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma

scientific article published on 13 December 2018

Genomic landscapes of breast fibroepithelial tumors

scientific article published on 5 October 2015

Genomic structure of human OKL38 gene and its differential expression in kidney carcinogenesis

scientific article published on 21 October 2003

Haem oxygenase 1 expression is associated with prognosis in cholangiocarcinoma patients and with drug sensitivity in xenografted mice

scientific article published on 4 January 2016

JAK-STAT and G-protein-coupled receptor signaling pathways are frequently altered in epitheliotropic intestinal T-cell lymphoma

scientific article published on 08 February 2016

Janus kinase 3-activating mutations identified in natural killer/T-cell lymphoma

scientific article

MED12 is frequently mutated in breast phyllodes tumours: a study of 112 cases

scientific article published on 27 May 2015

Mutational Signatures in Mandibular Ameloblastoma Correlate with Smoking

scientific article published on 27 March 2019

Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance.

scientific article

Oncogenic activation of JAK3-STAT signaling confers clinical sensitivity to PRN371, a novel selective and potent JAK3 inhibitor, in natural killer/T-cell lymphoma

scientific article published on 2 February 2018

Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma

scientific article published on 27 July 2018

Overexpression of microRNA-21 regulating PDCD4 during tumorigenesis of liver fluke-associated cholangiocarcinoma contributes to tumor growth and metastasis

scientific article published on 17 February 2013

PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis

scientific article published on 14 July 2020

Pathogenesis and biomarkers of natural killer T cell lymphoma (NKTL)

scientific article published on 15 March 2019

Pathogenesis of cholangiocarcinoma: From genetics to signalling pathways

scientific article published on 17 February 2015

Perioperative and follow-up results after central pancreatic head resection (Berne technique) in a consecutive series of patients with chronic pancreatitis

scientific article

Reproducing the molecular subclassification of peripheral T-cell lymphoma-NOS by immunohistochemistry

scientific article published on 01 December 2019

SETD2 histone modifier loss in aggressive GI stromal tumours

scientific article published on 3 September 2015

Serglycin is a theranostic target in nasopharyngeal carcinoma that promotes metastasis

scientific article published on 2 February 2011

Silencing expression of UO-44 (CUZD1) using small interfering RNA sensitizes human ovarian cancer cells to cisplatin in vitro.

scientific article

Successful therapeutic rechallenge after a severe episode of high dose methotrexate-induced choreoathetosis: A case report

scientific article published on 16 July 2019

The draft genome of tropical fruit durian (Durio zibethinus).

scientific article published on 9 October 2017

The role of 5' untranslated region in translational suppression of OKL38 mRNA in hepatocellular carcinoma

scientific article

Tissue Microbiome Profiling Identifies an Enrichment of Specific Enteric Bacteria in Opisthorchis viverrini Associated Cholangiocarcinoma

scientific article

Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma.

scientific article published on 21 June 2016

Whole exome sequencing identifies recessive germline mutations in FAM160A1 in familial NK/T cell lymphoma

scientific article published on 12 November 2018

Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma.

scientific article published on 30 June 2017

Whole-exome sequencing of breast cancer, malignant peripheral nerve sheath tumor and neurofibroma from a patient with neurofibromatosis type 1.

scientific article published on 03 October 2015

Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion

scientific article

Whole-genome reconstruction and mutational signatures in gastric cancer.

scientific article

Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma

scientific article published on 05 August 2020

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