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List of works by Eric Angevin

A first-in-human phase I study of SAR125844, a selective MET tyrosine kinase inhibitor, in patients with advanced solid tumours with MET amplification

scientific article published on 13 November 2017

A phase I/II, multiple-dose, dose-escalation study of siltuximab, an anti-interleukin-6 monoclonal antibody, in patients with advanced solid tumors

scientific article published on 21 February 2014

Analysis of the natural killer mediated immune response in metastatic renal cell carcinoma patients

scientific article published in April 2004

Antitumor activity in advanced cancer patients with thymic malignancies enrolled in early clinical drug development programs (Phase I trials) at Gustave Roussy

scientific article published on 22 June 2015

Bromohydrin pyrophosphate-stimulated Vgamma9delta2 T cells expanded ex vivo from patients with poor-prognosis neuroblastoma lyse autologous primary tumor cells

scientific article published on July 2010

Cardiac troponin I elevation and overall survival among cancer patients receiving investigational compounds during phase I trials

scientific article

Combination of interleukin-2 and gamma interferon in metastatic renal cell carcinoma

scientific article published in January 1993

Communication en oncologie dans le cadre d’essais thérapeutiques de phase I : mise en œuvre et évaluation d’un programme de formation

scientific article published in February 2015

Cost analysis of adverse events associated with non-small cell lung cancer management in France

scientific article published on 27 July 2017

Dendritic cell maturation overrules H-2D-mediated natural killer T (NKT) cell inhibition: critical role for B7 in CD1d-dependent NKT cell interferon gamma production

scientific article

Dendritic cell-based immunotherapy of cancer

scientific article

Dendritic cells (DC) promote natural killer (NK) cell functions: dynamics of the human DC/NK cell cross talk.

scientific article

Dendritic cells for NK/LAK activation: rationale for multicellular immunotherapy in neuroblastoma patients

scientific article published on 18 September 2002

Exosome-based immunotherapy

scientific article published on 16 January 2004

Exosomes as a tumor vaccine: enhancing potency through direct loading of antigenic peptides

scientific article published on September 2003

Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells

scientific article published on February 2004

Exosomes as potent cell-free peptide-based vaccine. II. Exosomes in CpG adjuvants efficiently prime naive Tc1 lymphocytes leading to tumor rejection

scientific article published on February 2004

Exosomes for cancer immunotherapy

scientific article published in January 2004

Exosomes in cancer immunotherapy: preclinical data

scientific article

FGFR inhibitor induced peripheral neuropathy in patients with advanced RCC.

scientific article published on 5 May 2010

First-in-human phase 1 of YS110, a monoclonal antibody directed against CD26 in advanced CD26-expressing cancers

scientific article

Generation of monocyte-derived dendritic cells from patients with renal cell cancer: modulation of their functional properties after therapy with biological response modifiers (IFN-alpha plus IL-2 and IL-12).

scientific article

IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 molecules

scientific article published in May 2004

Immune-related adverse events with immune checkpoint blockade: a comprehensive review

scientific article

Immunotherapy with interleukin-2 (IL2) and lymphokine-activated natural killer cells: improvement of clinical responses in metastatic renal cell carcinoma patients previously treated with IL2.

scientific article published in January 1994

In Vivo-Targeted Gene Delivery Using Antibody-Based Nonviral Vector

scientific article published on 10 June 2002

In vitro generation of cytotoxic effectors activated by interleukin 2 (IL-2): comparison of autologous peripheral blood stem cells (PBSC) from adults and children

scientific article published in April 2001

Isolation and characterization of renal cancer stem cells from patient-derived xenografts

scientific article

Long-term protective effect of mature DC-LAMP+ dendritic cell accumulation in sentinel lymph nodes containing micrometastatic melanoma

scientific article (publication date: July 2007)

Low-dose IL-2 treatment: Activation of discrete T- and NK-cell sub-populationsin vivo

scientific article published on 4 September 1995

Malignant effusions and immunogenic tumour-derived exosomes

scientific article published in July 2002

Metastatic renal-cell carcinoma patients treated with interleukin 2 or interleukin 2 plus interferon γ: Immunological monitoring

scientific article published on 15 June 1994

No evidence for abnormal immune activation in peripheral blood T cells in patients with hepatitis C virus (HCV) infection with or without cryoglobulinaemia. Multivirc Group

scientific article published in July 1998

Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects

scientific article published on August 2004

Patients aged over 75 years enrolled in Phase I clinical trials: the Gustave Roussy experience

scientific article published on 15 September 2015

Patterns of specific genomic alterations associated with poor prognosis in high-grade renal cell carcinomas ⬇️

scientific article published on October 15, 2001

Phase I study of dovitinib (TKI258), an oral FGFR, VEGFR, and PDGFR inhibitor, in advanced or metastatic renal cell carcinoma

scientific article published on 21 January 2013

Phase I trial of bortezomib daily dose: safety, pharmacokinetic profile, biological effects and early clinical evaluation in patients with advanced solid tumors

scientific article published on 2 November 2017

Phase I trial of everolimus in combination with thoracic radiotherapy in non-small-cell lung cancer.

scientific article

Phase I trial of sorafenib in combination with IFN alpha-2a in patients with unresectable and/or metastatic renal cell carcinoma or malignant melanoma

scientific article published on March 2007

Phase II results of Dovitinib (TKI258) in patients with metastatic renal cell cancer

scientific article published in April 2014

Phase II trial of thalidomide in renal-cell carcinoma

scientific article published in July 2002

Population pharmacokinetic/pharmacodynamic modeling to assist dosing schedule selection for dovitinib

scientific article

Preclinical assessment of JNJ-26854165 (Serdemetan), a novel tryptamine compound with radiosensitizing activity in vitro and in tumor xenografts.

scientific article published on 22 August 2011

Prospective validation of a prognostic score for patients in immunotherapy phase I trials: The Gustave Roussy Immune Score (GRIm-Score).

scientific article

Recombinant adenovirus shedding after intratumoral gene transfer in lung cancer patients

scientific article published in March 2003

Seeking the driver in tumours with apparent normal molecular profile on comparative genomic hybridization and targeted gene panel sequencing: what is the added value of whole exome sequencing?

scientific article published on 23 November 2015

Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma

scientific article published in March 2004

Sequential research-related biopsies in phase I trials: acceptance, feasibility and safety

scientific article published on 14 September 2011

T-cell receptor CDR3 size distribution analysis to evaluate specific T-cell response to cancer vaccines

scientific article published in June 1997

The decreased expression of CD3 ζ chains in cancer patients is not reversed BY IL-2 Administration

scientific article published on 15 December 1994

Totally implanted catheters to reduce catheter-related infections in patients receiving interleukin-2: a 2-year experience

scientific article published on September 1995

Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

scientific article

Vasculature analysis of patient derived tumor xenografts using species-specific PCR assays: evidence of tumor endothelial cells and atypical VEGFA-VEGFR1/2 signalings

scientific article

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