List of works - Margherita Doria

ADAR1 restricts LINE-1 retrotransposition.

scientific article published on 21 September 2016

ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor

scientific article

An RNA molecule copurifies with RNase P activity from Xenopus laevis oocytes ⬇️

scientific article published on May 11, 1991

Brief Report: L-Selectin (CD62L) Is Downregulated on CD4+ and CD8+ T Lymphocytes of HIV-1-Infected Individuals Naive for ART.

scientific article published on 19 March 2016

CD4 and major histocompatibility complex class I downregulation by the human immunodeficiency virus type 1 nef protein in pediatric AIDS progression

scientific article published on November 2003

CD4 downregulation by the human immunodeficiency virus type 1 Nef protein is dispensable for optimal output and functionality of viral particles in primary T cells

scientific article published on 29 September 2010

Chloroquine enhances human CD8+ T cell responses against soluble antigens in vivo

scientific article (publication date: 19 September 2005)

DNAM-1 Activating Receptor and Its Ligands: How Do Viruses Affect the NK Cell-Mediated Immune Surveillance during the Various Phases of Infection?

scientific article published on 30 July 2019

Dual regulation of L-selectin (CD62L) by HIV-1: Enhanced expression by Vpr in contrast with cell-surface down-modulation by Nef and Vpu

article

Early ART initiation during infancy preserves natural killer cells in young European adolescents living with HIV (CARMA cohort)

scientific article published on 01 July 2021

Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infection

scientific article

Expanding Phenotype of Schimke Immuno-Osseous Dysplasia: Congenital Anomalies of the Kidneys and of the Urinary Tract and Alteration of NK Cells

scientific article published on 15 November 2020

Exposure to Prostratin but Not Bryostatin-1 Improves Natural Killer Cell Functions Including Killing of CD4 T Cells Harboring Reactivated Human Immunodeficiency Virus

HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4+ T Lymphocytes

scientific article published on 11 March 2015

HIV-1 infection causes a down-regulation of genes involved in ribosome biogenesis

scientific article

Hexamethylene bisacetamide impairs NK cell-mediated clearance of acute T lymphoblastic leukemia cells and HIV-1-infected T cells that exit viral latency

article

Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity

scientific article published on January 2007

Internalization and intracellular retention of CD4 are two separate functions of the human immunodeficiency virus type 1 Nef protein

scientific article published in November 2007

MEOX2 Regulates the Growth and Survival of Glioblastoma Stem Cells by Modulating Genes of the Glycolytic Pathway and Response to Hypoxia

scientific article published on 06 May 2022

NK cells of HIV-1-infected patients with poor CD4+ T-cell reconstitution despite suppressive HAART show reduced IFN-γ production and high frequency of autoreactive CD56bright cells.

scientific article

Nef alleles from children with non-progressive HIV-1 infection modulate MHC-II expression more efficiently than those from rapid progressors.

scientific article published in May 2007

Partial T cell defects and expanded CD56bright NK cells in an SCID patient carrying hypomorphic mutation in the IL2RG gene

scientific article published on 11 May 2020

Plasma levels of soluble MICA and ULBP2 are increased in children allergic to dust mites

Potential of the NKG2D/NKG2DL Axis in NK Cell-Mediated Clearance of the HIV-1 Reservoir

scientific article published on 11 September 2019

Role of the CD4 Down-Modulation Activity of Nef in HIV-1 Infectivity ⬇️

scientific article published on October 1, 2011

Site selection by Xenopus laevis RNAase P.

scientific article

Soluble ligands for the NKG2D receptor are released during HIV-1 infection and impair NKG2D expression and cytotoxicity of NK cells

scientific article published on 8 February 2013

Structural defects and variations in the HIV-1 nef gene from rapid, slow and non-progressor children

article

The ADAR1 editing enzyme is encapsidated into HIV-1 virions

scientific article published on 9 September 2015

The HIV-1 Nef protein has a dual role in T cell receptor signaling in infected CD4+ T lymphocytes

article

The HIV-1 Tat protein modulates CD4 expression in human T cells through the induction of miR-222.

scientific article published on 6 March 2014

The Pro78 residue regulates the capacity of the human immunodeficiency virus type 1 Nef protein to inhibit recycling of major histocompatibility complex class I molecules in an SH3-independent manner

scientific article

The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport

scientific article

The histone deacetylase inhibitor SAHA simultaneously reactivates HIV-1 from latency and up-regulates NKG2D ligands sensitizing for natural killer cell cytotoxicity

scientific article published on 6 July 2017

The human immunodeficiency virus type 1 Nef and Vpu proteins downregulate the natural killer cell-activating ligand PVR.

scientific article published on February 2012

The human immunodeficiency virus type 1 Vpr protein upregulates PVR via activation of the ATR-mediated DNA damage response pathway

scientific article

Vδ2 T-Cells Kill ZIKV-Infected Cells by NKG2D-Mediated Cytotoxicity

scientific article published on 12 September 2019

List of works by Margherita Doria

ADAR1 restricts LINE-1 retrotransposition.

ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor

An RNA molecule copurifies with RNase P activity from Xenopus laevis oocytes ⬇️

Brief Report: L-Selectin (CD62L) Is Downregulated on CD4+ and CD8+ T Lymphocytes of HIV-1-Infected Individuals Naive for ART.

CD4 and major histocompatibility complex class I downregulation by the human immunodeficiency virus type 1 nef protein in pediatric AIDS progression

CD4 downregulation by the human immunodeficiency virus type 1 Nef protein is dispensable for optimal output and functionality of viral particles in primary T cells

Chloroquine enhances human CD8+ T cell responses against soluble antigens in vivo

DNAM-1 Activating Receptor and Its Ligands: How Do Viruses Affect the NK Cell-Mediated Immune Surveillance during the Various Phases of Infection?

Dual regulation of L-selectin (CD62L) by HIV-1: Enhanced expression by Vpr in contrast with cell-surface down-modulation by Nef and Vpu

Early ART initiation during infancy preserves natural killer cells in young European adolescents living with HIV (CARMA cohort)

Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infection

Expanding Phenotype of Schimke Immuno-Osseous Dysplasia: Congenital Anomalies of the Kidneys and of the Urinary Tract and Alteration of NK Cells

Exposure to Prostratin but Not Bryostatin-1 Improves Natural Killer Cell Functions Including Killing of CD4 T Cells Harboring Reactivated Human Immunodeficiency Virus

HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4+ T Lymphocytes

HIV-1 infection causes a down-regulation of genes involved in ribosome biogenesis

Hexamethylene bisacetamide impairs NK cell-mediated clearance of acute T lymphoblastic leukemia cells and HIV-1-infected T cells that exit viral latency

Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity

Internalization and intracellular retention of CD4 are two separate functions of the human immunodeficiency virus type 1 Nef protein

MEOX2 Regulates the Growth and Survival of Glioblastoma Stem Cells by Modulating Genes of the Glycolytic Pathway and Response to Hypoxia

NK cells of HIV-1-infected patients with poor CD4+ T-cell reconstitution despite suppressive HAART show reduced IFN-γ production and high frequency of autoreactive CD56bright cells.

Nef alleles from children with non-progressive HIV-1 infection modulate MHC-II expression more efficiently than those from rapid progressors.

Partial T cell defects and expanded CD56bright NK cells in an SCID patient carrying hypomorphic mutation in the IL2RG gene

Plasma levels of soluble MICA and ULBP2 are increased in children allergic to dust mites

Potential of the NKG2D/NKG2DL Axis in NK Cell-Mediated Clearance of the HIV-1 Reservoir

Role of the CD4 Down-Modulation Activity of Nef in HIV-1 Infectivity ⬇️

Site selection by Xenopus laevis RNAase P.

Soluble ligands for the NKG2D receptor are released during HIV-1 infection and impair NKG2D expression and cytotoxicity of NK cells

Structural defects and variations in the HIV-1 nef gene from rapid, slow and non-progressor children

The ADAR1 editing enzyme is encapsidated into HIV-1 virions

The HIV-1 Nef protein has a dual role in T cell receptor signaling in infected CD4+ T lymphocytes

The HIV-1 Tat protein modulates CD4 expression in human T cells through the induction of miR-222.

The Pro78 residue regulates the capacity of the human immunodeficiency virus type 1 Nef protein to inhibit recycling of major histocompatibility complex class I molecules in an SH3-independent manner

The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport

The histone deacetylase inhibitor SAHA simultaneously reactivates HIV-1 from latency and up-regulates NKG2D ligands sensitizing for natural killer cell cytotoxicity

The human immunodeficiency virus type 1 Nef and Vpu proteins downregulate the natural killer cell-activating ligand PVR.

The human immunodeficiency virus type 1 Vpr protein upregulates PVR via activation of the ATR-mediated DNA damage response pathway

Vδ2 T-Cells Kill ZIKV-Infected Cells by NKG2D-Mediated Cytotoxicity