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List of works by Gerhard Wiche

5' trans-splicing repair of the PLEC1 gene

scientific article published on 8 November 2007

A site-specific plectin mutation causes dominant epidermolysis bullosa simplex Ogna: two identical de novo mutations

scientific article (publication date: 2002)

Actin-binding domain of mouse plectin. Crystal structure and binding to vimentin

scientific article

BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin

scientific article

Chemical chaperone ameliorates pathological protein aggregation in plectin-deficient muscle

scientific article

Determining the mechanical properties of plectin in mouse myoblasts and keratinocytes

scientific article

Direct binding of plectin to Fer kinase and negative regulation of its catalytic activity

scientific journal article

Epiplakin attenuates experimental mouse liver injury by chaperoning keratin reorganization

scientific journal article

Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules

scientific journal article

Epiplakin gene analysis in mouse reveals a single exon encoding a 725-kDa protein with expression restricted to epithelial tissues

scientific journal article

FIP-2, an IkappaB-kinase-gamma-related protein, is associated with the Golgi apparatus and translocates to the marginal band during chicken erythroblast differentiation

scientific article

Ferritin associates with marginal band microtubules

scientific article

Fused in sarcoma (FUS) interacts with the cytolinker protein plectin: implications for FUS subcellular localization and function

scientific article

Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat.

scientific article

High-pressure freezing and low-temperature fixation of cell monolayers grown on sapphire coverslips

scientific article

Intermediate filament-associated cytolinker plectin 1c destabilizes microtubules in keratinocytes

scientific article published on 30 January 2013

Keratins Stabilize Hemidesmosomes through Regulation of β4-Integrin Turnover

scientific article published on 10 February 2015

Linking cytoarchitecture to metabolism: sarcolemma-associated plectin affects glucose uptake by destabilizing microtubule networks in mdx myofibers

scientific article published on 12 June 2013

Mechanosensing through focal adhesion-anchored intermediate filaments

scientific article published on 17 December 2013

Microtubule-associated protein 1A (MAP1A) and MAP1B: light chains determine distinct functional properties

scientific article (publication date: 15 March 2002)

Molecular architecture and function of the hemidesmosome

scientific article published on 09 December 2014

Molecular architecture and function of the hemidesmosome

scientific article published on 29 May 2015

Networking and anchoring through plectin: a key to IF functionality and mechanotransduction

scientific article

Neuromuscular synapse integrity requires linkage of acetylcholine receptors to postsynaptic intermediate filament networks via rapsyn-plectin 1f complexes

scientific article

Plectin gene defects lead to various forms of epidermolysis bullosa simplex

scientific article published on January 2010

Plectin isoform 1-dependent nuclear docking of desmin networks affects myonuclear architecture and expression of mechanotransducers

scientific article

Plectin isoform 1b mediates mitochondrion-intermediate filament network linkage and controls organelle shape

scientific article

Plectin isoform P1b and P1d deficiencies differentially affect mitochondrial morphology and function in skeletal muscle

scientific article published on 27 May 2015

Plectin isoforms as organizers of intermediate filament cytoarchitecture

scientific article published on January 2011

Plectin regulates the organization of glial fibrillary acidic protein in Alexander disease

scientific article

Plectin reinforces vascular integrity by mediating crosstalk between the vimentin and the actin networks.

scientific article

Plectin-RACK1 (receptor for activated C kinase 1) scaffolding: a novel mechanism to regulate protein kinase C activity

scientific article published on 14 February 2004

Plectin-controlled keratin cytoarchitecture affects MAP kinases involved in cellular stress response and migration

scientific article

Plectin-intermediate filament partnership in skin, skeletal muscle, and peripheral nerve

scientific article published on 09 June 2013

Plectin-isoform-specific rescue of hemidesmosomal defects in plectin (-/-) keratinocytes

scientific article published on February 2003

Plectin.

scientific article

Rapid microwave fixation of cell monolayers preserves microtubule-associated cell structures

scientific article

Schwann Cell Expressed Nogo-B Modulates Axonal Branching of Adult Sensory Neurons Through the Nogo-B Receptor NgBR.

scientific article published on 23 November 2015

Silencing GFAP isoforms in astrocytoma cells disturbs laminin-dependent motility and cell adhesion

scientific article published on 2 April 2014

Stress-induced recruitment of epiplakin to keratin networks increases their resistance to hyperphosphorylation-induced disruption

scientific journal article

Targeted ablation of plectin isoform 1 uncovers role of cytolinker proteins in leukocyte recruitment

scientific article

Targeted proteolysis of plectin isoform 1a accounts for hemidesmosome dysfunction in mice mimicking the dominant skin blistering disease EBS-Ogna

scientific article (publication date: December 2011)

The many faces of plectin and plectinopathies: pathology and mechanisms

scientific article

TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton

scientific article

Trichoplein/mitostatin regulates endoplasmic reticulum-mitochondria juxtaposition

scientific article

Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer

scientific article

Vimentin intermediate filament and plectin provide a scaffold for invadopodia, facilitating cancer cell invasion and extravasation for metastasis

scientific article published on 15 April 2014

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