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List of works by Stephen M Richardson

A Membranome-Centered Approach Defines Novel Biomarkers for Cellular Subtypes in the Intervertebral Disc

scientific article published in April 2018

Acidic pH promotes intervertebral disc degeneration: Acid-sensing ion channel -3 as a potential therapeutic target

scientific article

An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness.

scientific article published on 12 June 2018

An optimized culture system for notochordal cell expansion with retention of phenotype

scientific article published on 26 July 2018

An understanding of intervertebral disc development, maturation and cell phenotype provides clues to direct cell-based tissue regeneration therapies for disc degeneration.

scientific article published on 29 April 2014

Bi-directional exchange of membrane components occurs during co-culture of mesenchymal stem cells and nucleus pulposus cells

scientific article

Biogelx: Cell Culture on Self-Assembling Peptide Gels

scientific article published on 01 January 2018

Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation.

scientific article

Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1.

scientific article

Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype

scientific article published in September 2010

Comparative quantification of the surfaceome of human multipotent mesenchymal progenitor cells.

scientific article

Correction: Human decellularized bone scaffolds from aged donors show improved osteoinductive capacity compared to young donor bone

scientific article

Degenerate human nucleus pulposus cells promote neurite outgrowth in neural cells

scientific article

Degenerate intervertebral disc-like pH induces a catabolic mechanoresponse in human nucleus pulposus cells

scientific article published on 11 March 2018

EGR1 controls divergent cellular responses of distinctive nucleus pulposus cell types

scientific article

Exploiting the role of nanoparticle shape in enhancing hydrogel adhesive and mechanical properties

scientific article published on 17 March 2020

Expression of receptors for putative anabolic growth factors in human intervertebral disc: implications for repair and regeneration of the disc.

scientific article published in December 2005

Expression of semaphorin 3A and its receptors in the human intervertebral disc: potential role in regulating neural ingrowth in the degenerate intervertebral disc.

scientific article

Fabrication of 3-dimensional cellular constructs via microstereolithography using a simple, three-component, poly(ethylene glycol) acrylate-based system.

scientific article published on 5 December 2012

Graphene oxide: A growth factor delivery carrier to enhance chondrogenic differentiation of human mesenchymal stem cells in 3D hydrogels

scientific article published on 17 July 2019

Growth differentiation factor 6 and transforming growth factor-beta differentially mediate mesenchymal stem cell differentiation, composition, and micromechanical properties of nucleus pulposus constructs

scientific article

High BMPR2 expression leads to enhanced SMAD1/5/8 signalling and GDF6 responsiveness in human adipose-derived stem cells: implications for stem cell therapies for intervertebral disc degeneration

scientific article published on 01 January 2020

Human Adipose-Derived Stem Cells Exhibit Enhanced Proliferative Capacity and Retain Multipotency Longer than Donor-Matched Bone Marrow Mesenchymal Stem Cells during Expansion In Vitro

scientific article

Human decellularized bone scaffolds from aged donors show improved osteoinductive capacity compared to young donor bone

scientific article

Human notochordal cell transcriptome unveils potential regulators of cell function in the developing intervertebral disc

scientific article published in Scientific Reports

Hydroxyapatite-decorated Fmoc-hydrogel as a bone-mimicking substrate for osteoclast differentiation and culture

scientific article published on 13 November 2021

Identification of novel nucleus pulposus markers: Interspecies variations and implications for cell-based therapiesfor intervertebral disc degeneration.

scientific article published on 19 August 2013

Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc.

scientific article published on 20 August 2009

Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism

scientific article published on 16 September 2019

Introducing chemical functionality in Fmoc-peptide gels for cell culture.

scientific article

Low-density subculture: a technical note on the importance of avoiding cell-to-cell contact during mesenchymal stromal cell expansion

scientific article published on 7 July 2015

Material Characterization of PCL:PLLA Electrospun Fibers Following Six Months Degradation In Vitro

scientific article published on 21 March 2020

Mesenchymal stem cells in regenerative medicine: Focus on articular cartilage and intervertebral disc regeneration

scientific article

Microparticles for controlled growth differentiation factor 6 delivery to direct adipose stem cell-based nucleus pulposus regeneration

scientific article published on 19 June 2019

Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration

scientific article

Novel Immortal Cell Lines Support Cellular Heterogeneity in the Human Annulus Fibrosus

scientific article published on 21 January 2016

Novel immortal human cell lines reveal subpopulations in the nucleus pulposus

scientific article

Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading

scientific article published on 12 September 2019

Photo-responsive hydrogels with photoswitchable mechanical properties allow time-resolved analysis of cellular responses to matrix stiffening.

scientific article published on 12 February 2018

Photoresponsive Hydrogels with Photoswitchable Stiffness: Emerging Platforms to Study Temporal Aspects of Mesenchymal Stem Cell Responses to Extracellular Stiffness Regulation

scientific article published on 01 January 2019

Povidone-Iodine Has a Profound Effect on In Vitro Osteoblast Proliferation and Metabolic Function and Inhibits Their Ability to Mineralize and Form Bone

scientific article published on 3 December 2015

Regenerative Response of Degenerate Human Nucleus Pulposus Cells to GDF6 Stimulation

scientific article published on 27 September 2020

Robust alginate/hyaluronic acid thiol-yne click-hydrogel scaffolds with superior mechanical performance and stability for load-bearing soft tissue engineering

scientific article published on 15 November 2019

Self-assembling peptide hydrogel for intervertebral disc tissue engineering.

scientific article published on 24 September 2016

Self-healing, stretchable and robust interpenetrating network hydrogels

scientific article published on 21 September 2018

Simultaneous orthogonal dual-click approach to tough, in-situ-forming hydrogels for cell encapsulation

scientific article published on 26 January 2015

Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord-specific markers during early human intervertebral disc development

scientific article published on 22 February 2016

Stem cell regeneration of degenerated intervertebral discs: current status (update).

scientific article published on December 2013

The use of a novel bone allograft wash process to generate a biocompatible, mechanically stable and osteoinductive biological scaffold for use in bone tissue engineering.

scientific article

Therapeutic potential of growth differentiation factors in the treatment of degenerative disc diseases

scientific article published on 08 March 2019

Thermally-triggered gelation of PLGA dispersions: towards an injectable colloidal cell delivery system

scientific article published on 22 December 2009

Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes

scientific article published on 11 February 2010

Understanding the native nucleus pulposus cell phenotype has important implications for intervertebral disc regeneration strategies.

scientific article published on January 2013

Urocortin-1 Is Chondroprotective in Response to Acute Cartilage Injury via Modulation of Piezo1

scientific article published on 04 May 2022

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