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List of works by Hannah J Gould

"Auto-anti-IgE": naturally occurring IgG anti-IgE antibodies may inhibit allergen-induced basophil activation.

scientific article

80S ribosomal proteins

scientific article published on September 1972

80S-ribosomal proteins.

scientific article

A Phl p 7-specific IgG4 antibody inhibits allergic patients IgE cross-reactivity to allergens from the EF-hand family: importance of affinity and degree of cross-reactivity

A novel IgE-neutralizing antibody for the treatment of severe uncontrolled asthma

scientific article

A reversible conformational transition in chromatin ⬇️

scientific article published on May 17, 1979

A study of the alkaline hydrolysis of fractionated reticulocyte ribosomal ribonucleic acid and its relevance to secondary structure

scientific article published on February 1968

A tool kit for rapid cloning and expression of recombinant antibodies

scientific article

A transcriptional regulatory element in the coding sequence of the human Bcl-2 gene.

scientific article

Activity of human monocytes in IgE antibody-dependent surveillance and killing of ovarian tumor cells.

scientific article

Allergen specificity of IgG4-expressing B cells in patients with grass pollen allergy undergoing immunotherapy

scientific article published on 13 May 2012

Allergen-specific IgE is not detectable in the bronchial mucosa of nonatopic asthmatic patients

scientific article published in May 2014

AllergoOncology: Microbiota in allergy and cancer-A European Academy for Allergy and Clinical Immunology position paper.

scientific article published on 6 March 2019

AllergoOncology: ultra-low IgE, a potential novel biomarker in cancer-a Position Paper of the European Academy of Allergy and Clinical Immunology (EAACI)

scientific article published on 17 July 2020

Alpha-helical coiled-coil stalks in the low-affinity receptor for IgE (Fc epsilon RII/CD23) and related C-type lectins ⬇️

scientific article published on January 15, 1992

Antibodies and superantibodies in patients with chronic rhinosinusitis with nasal polyps

scientific article published on 19 September 2016

Attenuation of IgE affinity for FcepsilonRI radically reduces the allergic response in vitro and in vivo

scientific article published on 13 August 2008

Basis of the 1:1 stoichiometry of the high affinity receptor FcεRI-IgE complex

scientific article published on 01 January 1997

Biased use of VH5 IgE-positive B cells in the nasal mucosa in allergic rhinitis

scientific article published in August 2005

Biosynthesis of the Crystal Protein of Bacillus thuringiensis var. tolworth. 2. On the Relation of Transcriptional and Translational Events in the Growth Cycle

scientific article published on 01 September 1973

Biosynthesis of the crystal protein of Bacillus thuringiensis var. tolworth. 1. Kinetics of formation of the polypeptide components of the crystal protein in vivo

scientific article published in September 1973

CD23/Fc epsilon RII and its soluble fragments can form oligomers on the cell surface and in solution.

scientific article published on February 1995

Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E

scientific article

Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells.

scientific article

Characterisation of eukaryotic ribosomal proteins ⬇️

scientific article published on December 31, 1976

Characterization of human complement receptor type 2 (CR2/CD21) as a receptor for IFN-alpha: a potential role in systemic lupus erythematosus

scientific article published on 01 July 2006

Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma

scientific article published on 01 January 2007

Cleavage of the low-affinity receptor for human IgE (CD23) by a mite cysteine protease: nature of the cleaved fragment in relation to the structure and function of CD23.

scientific article published on March 1997

Comparative reactivity of human IgE to cynomolgus monkey and human effector cells and effects on IgE effector cell potency.

scientific article published on 14 January 2014

Comprehensive FISH probe design tool applied to imaging human immunoglobulin class switch recombination

scientific article

Conformation of the isolated cepsilon3 domain of IgE and its complex with the high-affinity receptor, FcepsilonRI.

scientific article

Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcɛRI.

scientific article

Conformational plasticity at the IgE-binding site of the B-cell receptor CD23

scientific article

Conservation of the structure of ribosomal RNA during evolution

scientific article published in March 1969

Crystal protein of Bacillus thuringiensis var. tolworthi. Subunit structure and toxicity to Pieris brassicae

scientific article

Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor Fc RI

scientific article

Crystal structure of the human IgG4 CH3 dimer reveals the role of Arg409 in the mechanism of Fab-arm exchange ⬇️

scientific article published on November 17, 2012

Cytokinergic IgE Action in Mast Cell Activation

scientific article

DNase I hypersensitive sites in the chromatin of human mu immunoglobulin heavy-chain genes

scientific article published in December 1983

Deletional switch recombination occurs in interleukin-4-induced isotype switching to IgE expression by human B cells.

scientific article published on September 1991

Detection of refractive index changes in individual living cells by means of surface plasmon resonance imaging.

scientific article published on 31 July 2010

Domain One of the High Affinity IgE Receptor, FcεRI, Regulates Binding to IgE through Its Interface with Domain Two

scientific article published in Journal of Biological Chemistry

Downregulation of polymeric immunoglobulin receptor and secretory IgA antibodies in eosinophilic upper airway diseases.

scientific article

Early pre-B cells from normal and X-linked agammaglobulinaemia produce Cμ without an attached VH region

scientific article published in Nature

Effect of DDT on egg-laying by Oscinella frit L.

scientific article published in December 1958

Endocytosis and recycling of the complex between CD23 and HLA-DR in human B cells

scientific article published in July 2001

Enumeration of rabbit reticulocyte ribosomal proteins

scientific article published on 01 December 1971

Epidemiological associations of allergy, IgE and cancer.

scientific article published on October 2013

Epitope specificity determines cross-protection of a SIT-induced IgG4 antibody

scientific article

Expression of IL-4, Cϵ RNA, and Iϵ RNA in the nasal mucosa of patients with seasonal rhinitis: Effect of topical corticosteroids☆☆☆★★★

scientific article published on 01 March 1998

Expression of IgE heavy chain transcripts in the sinus mucosa of atopic and nonatopic patients with chronic sinusitis.

scientific article

Expression of ɛ germ-line gene transcripts and mRNA for the ɛ heavy chain of IgE in nasal B cells and the effects of topical corticosteroid

article

Facilitated diffusion of a DNA binding protein on chromatin.

scientific article published on December 1986

Fractionation of low molecular weight fragments of ribosomal and viral RNA by polyacrylamide gel electrophoresis

scientific article published in April 1969

Function of CD23 in the response of human B cells to antigen

scientific article published on February 1997

Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of FcɛRI-mediated basophil activation by a tumour-specific IgE antibody to evaluate the risk of type I hypersensitivity.

scientific article published on 16 May 2011

Heterogeneous Glycosylation of Immunoglobulin E Constructs Characterized by Top-Down High-Resolution 2-D Mass Spectrometry†

scientific article published on 01 March 2000

High resolution analysis of the chromatin landscape of the IgE switch region in human B cells

scientific article

Human IgE against the major allergen Bet v 1 - defining an epitope with limited cross-reactivity between different PR-10 family proteins

scientific article

Identification of Contact Residues in the IgE Binding Site of Human FcεRIα†

scientific article published on 01 December 1997

IgE Trimers Drive SPE-7 Cytokinergic Activity

scientific article published on 15 August 2017

IgE binds asymmetrically to its B cell receptor CD23

scientific article

IgE immunotherapy: a novel concept with promise for the treatment of cancer

scientific article published on January 2014

IgE in allergy and asthma today

scientific article published on March 2008

IgE responses in mouse and man and the persistence of IgE memory

scientific article

IgE-antibody-dependent immunotherapy of solid tumors: cytotoxic and phagocytic mechanisms of eradication of ovarian cancer cells.

scientific article published on September 2007

IgEs targeted on tumor cells: therapeutic activity and potential in the design of tumor vaccines

scientific article published in July 2001

IgG4 inhibits peanut-induced basophil and mast cell activation in peanut-tolerant children sensitized to peanut major allergens

scientific article published on 7 February 2015

Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and Treatment

scientific article

Immunoglobulin gene organisation and expression in haemopoietic stem cell leukaemia.

scientific article published on January 1983

Increased IgA production by B-cells in COPD via lung epithelial interleukin-6 and TACI pathways

scientific article published on 23 December 2014

Increases in allergen-specific IgE in BAL after segmental allergen challenge in atopic asthmatics.

scientific article published on January 2002

Influence of seasonal exposure to grass pollen on local and peripheral blood IgE repertoires in patients with allergic rhinitis

scientific article

Inhibition of allergen-dependent IgE activity by antibodies of the same specificity but different class

scientific article published on 28 March 2015

Inhibition of mast cell sensitization in vitro by a human immunoglobulin epsilon-chain fragment synthesized in Escherichia coli.

scientific article published in September 1985

Interplay between Affinity and Valency in Effector Cell Degranulation: A Model System with Polcalcin Allergens and Human Patient-Derived IgE Antibodies

scientific article published on 28 August 2019

Intrinsic properties of germinal center-derived B cells promote their enhanced class switching to IgE.

scientific article published on 25 June 2015

Isolation and identification of separated messenger RNAs for rabbit α and β globin

scientific article published on 01 May 1975

Laboratory and field investigations with organophosphorus resistant Tetranychus urticae on strawberries ⬇️

scientific article published on May 1, 1973

Local Clonal Diversification and Dissemination of B Lymphocytes in the Human Bronchial Mucosa

scientific article published on 07 September 2018

Local IgE in non-allergic rhinitis.

scientific article published on May 2015

Local expression of ϵ germline gene transcripts and RNA for the ϵ heavy chain of IgE in the bronchial mucosa in atopic and nonatopic asthma

article

Local receptor revision and class switching to IgE in chronic rhinosinusitis with nasal polyps.

scientific article published on 15 November 2012

Local somatic hypermutation and class switch recombination in the nasal mucosa of allergic rhinitis patients.

scientific article published on November 2003

Mapping of the CD23 Binding Site on Immunoglobulin E (IgE) and Allosteric Control of the IgE-FcϵRI Interaction ⬇️

scientific article published on July 19, 2012

Mechanism of the antigen-independent cytokinergic SPE-7 IgE activation of human mast cells in vitro

scientific article

Molecular weight distribution of proteins in rabbit reticulocyte ribosomal subunits

scientific article published in October 1971

Molecular weight distribution of ribosomal proteins from several vertebrate species

scientific article published in December 1976

Molecular weights of separated rabbit alpha-and beta-globin messenger RNAs

scientific article

Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies

scientific article (publication date: 2011)

Mutagenesis within human FcepsilonRIalpha differentially affects human and murine IgE binding.

scientific article published on February 2002

Ontogeny of human IgE-expressing B cells and plasma cells

scientific article published on 08 April 2016

Participation of the N-Terminal Region of Cε3 in the Binding of Human IgE to Its High-Affinity Receptor FcεRI ⬇️

scientific article published on December 16, 1997

Peptide analogs that inhibit IgE-Fc epsilon RI alpha interactions ameliorate the development of lethal graft-versus-host disease

scientific article published on October 1, 1997

Persistent IgE synthesis in the nasal mucosa of hay fever patients ⬇️

scientific article published on December 1, 2001

Phosphorylation of rabbit reticulocyte ribosomal proteins in vitro

scientific article published in February 1973

Proteins of Rabbit Reticulocyte Ribosomal Subunits ⬇️

scientific article published on September 12, 1970

Quantitation of eukaryotic ribosomal proteins separated by two-dimensional polyacrylamide gel electrophoresis

scientific article published in August 1975

Recombinant IgE antibodies for passive immunotherapy of solid tumours: from concept towards clinical application.

scientific article published on 03 December 2011

Recombinant human IgE.

scientific article

Regulation of IgE production requires oligomerization of CD23.

scientific article

Regulation of human epsilon germline transcription: role of B-cell-specific activator protein

scientific article published on 01 May 1997

Role of IgE receptors in IgE antibody-dependent cytotoxicity and phagocytosis of ovarian tumor cells by human monocytic cells.

scientific article

Role of Optical Isomers in Determining the Antigenicity of Synthetic Polypeptides

scientific article published in Nature

STUDIES ON SYNTHETIC POLYPEPTIDE ANTIGENS. 13. THE EFFECTS OF SYSTEMATIC VARIATION IN COMPOSITION AND CHEMICAL MODIFICATIONS OF THE SYNTHETIC POLYPEPTIDES ON THE ANTIBODY-SYNTHETIC POLYPEPTIDE ANTIGEN INTERACTION

scientific article published in Journal of Biological Chemistry

STUDIES ON SYNTHETIC POLYPEPTIDE ANTIGENS. XI. THE ANTIGENICITY OF OPTICALLY ISOMERIC SYNTHETIC POLYPEPTIDES

scientific article published in Journal of Biological Chemistry

STUDIES ON SYNTHETIC POLYPEPTIDE ANTIGENS. XII. THE EFFECTS OF PH, IONIC STRENGTH, TEMPERATURE, AND NONAQUEOUS SOLVENTS ON ANTIBODY ACTIVITY AND THE ANTIBODY-SYNTHETIC POLYPEPTIDE INTERACTION

scientific article published in Journal of Biological Chemistry

Secretion of recombinant human IgE-Fc by mammalian cells and biological activity of glycosylation site mutants

article

Soluble CD23 controls IgE synthesis and homeostasis in human B cells.

scientific article

Soluble CD23 monomers inhibit and oligomers stimulate IGE synthesis in human B cells

scientific article

Stoichiometry and thermodynamics of the interaction between the Fc fragment of human IgG1 and its low-affinity receptor Fc gamma RIII.

scientific article published in October 1995

Structural Determinants of Unique Properties of Human IgG4-Fc

scientific article

Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody

scientific article published in Scientific Reports

Structural basis of the IgE-Fc epsilon RI interaction

scientific article

Structure based design and characterization of peptides that inhibit IgE binding to its high-affinity receptor

article

Structure of a patient-derived antibody in complex with allergen reveals simultaneous conventional and superantigen-like recognition

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structure-based design of peptides that inhibit IgE binding to its high-affinity receptor Fc epsilon RI.

scientific article published on May 1997

THE CONFORMATION AND HYDROGEN ION EQUILIBRIUM OF NORMAL RABBIT GAMMA-GLOBULIN

scientific article published in Journal of Biological Chemistry

The allergic march from Staphylococcus aureus superantigens to immunoglobulin E.

scientific article published on January 2007

The assay of globin gene transcription in reconstituted chromatin

scientific article published on January 1, 1978

The biology of IGE and the basis of allergic disease

scientific article

The crystal structure of IgE Fc reveals an asymmetrically bent conformation

scientific article

The dissociation of reticulocyte polysomes into subunits and the location of messenger RNA

article

The human IgE network

scientific article

The molecular weight of rabbit globin messenger RNA's

scientific article published in March 1973

The oligomeric nature of the murine Fc epsilon RII/CD23. Implications for function.

scientific article published in March 1993

The structure of human CD23 and its interactions with IgE and CD21.

scientific article published on September 2005

The structure of the IgE Cepsilon2 domain and its role in stabilizing the complex with its high-affinity receptor FcepsilonRIalpha

scientific article

The transcription factor B cell-specific activator protein (BSAP) enhances both IL-4- and CD40-mediated activation of the human epsilon germline promoter

scientific article published on 01 June 1997

The who, where, and when of IgE in allergic airway disease.

scientific article published on 09 December 2011

Thermodynamics of the interaction of human immunoglobulin E with its high-affinity receptor Fc epsilon RI.

scientific article published in June 1998

Transcription of Ig germline genes in single human B cells and the role of cytokines in isotype determination

article

Transcription of globin genes in reticulocyte chromatin

scientific article published on September 1979

Upregulation of FcϵRI on human basophils by IgE antibody is mediated by interaction of IgE with FcϵRI☆☆☆★

scientific article published on 01 August 1999

Zonal Ultracentrifuge for the Separation of Ribosomal Subunits

scientific article

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