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List of works by Sophia N. Karagiannis

<scp>AllergoOncology</scp>: Biomarkers and refined classification for research in the allergy and glioma nexus—A joint <scp>EAACI‐EANO</scp> position paper

scientific article published in 2024

A Novel Antibody-Drug Conjugate (ADC) Delivering a DNA Mono-Alkylating Payload to Chondroitin Sulfate Proteoglycan (CSPG4)-Expressing Melanoma

scientific article published on 22 April 2020

A novel IgE-neutralizing antibody for the treatment of severe uncontrolled asthma

scientific article

Activity of human monocytes in IgE antibody-dependent surveillance and killing of ovarian tumor cells.

scientific article

Advances in the treatment of melanoma.

scientific article published on April 2012

AllergoOncology: Expression platform development and functional profiling of an anti-HER2 IgE antibody

scientific article published on 27 May 2019

AllergoOncology: Generating a canine anticancer IgE against the epidermal growth factor receptor

scientific article published on 07 May 2018

AllergoOncology: High innate IgE levels are decisive for the survival of cancer-bearing mice

scientific article published on 29 July 2019

AllergoOncology: IgE- and IgG4-mediated immune mechanisms linking allergy with cancer and their translational implications

scientific article published on 16 May 2017

AllergoOncology: Microbiota in allergy and cancer-A European Academy for Allergy and Clinical Immunology position paper.

scientific article published on 6 March 2019

AllergoOncology: Opposite outcomes of immune tolerance in allergy and cancer.

scientific article published on 16 September 2017

AllergoOncology: the role of IgE-mediated allergy in cancer

scientific article

AllergoOncology: ultra-low IgE, a potential novel biomarker in cancer-a Position Paper of the European Academy of Allergy and Clinical Immunology (EAACI)

scientific article published on 17 July 2020

An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment.

scientific article published on July 2017

An immunologically relevant rodent model demonstrates safety of therapy using a tumour-specific IgE.

scientific article published on 13 April 2018

Anti-Folate Receptor Alpha-Directed Antibody Therapies Restrict the Growth of Triple-negative Breast Cancer

scientific article published on 01 August 2018

Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs).

scientific article published on 20 November 2017

Antibody therapies for melanoma: new and emerging opportunities to activate immunity (Review).

scientific article

Association of Serum Immunoglobulin Levels with Solid Cancer: A Systematic Review and Meta-analysis

scientific article published on 08 January 2020

Atopy and prostate cancer: Is there a link between circulating levels of IgE and PSA in humans?

scientific article published on 9 August 2017

B cells and the humoral response in melanoma: The overlooked players of the tumor microenvironment

scientific article

BRAF inhibitors: resistance and the promise of combination treatments for melanoma

scientific article published on 3 August 2017

Basophil activation test in cancer patient blood evaluating potential hypersensitivity to an anti-tumor IgE therapeutic candidate

scientific article published on 22 February 2020

Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome

scientific article published on 07 July 2020

Beta-glucan contamination of pharmaceutical products: How much should we accept?

scientific article

Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types.

scientific article published in January 2017

Chronic inflammation markers are associated with risk of pancreatic cancer in the Swedish AMORIS cohort study

scientific article published on 29 August 2019

Colocalisation of insulin and IGF‐1 receptors in cultured rat sensory and sympathetic ganglion cells ⬇️

scientific article published on October 1, 1997

Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma

article

Development of downstream processing to minimize beta-glucan impurities in GMP-manufactured therapeutic antibodies.

scientific article published on 7 September 2016

Dysregulated Antibody, Natural Killer Cell and Immune Mediator Profiles in Autoimmune Thyroid Diseases

scientific article published on 09 March 2020

Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma

scientific article

Endocytosis and recycling of the complex between CD23 and HLA-DR in human B cells

scientific article published in July 2001

Engineering and stable production of recombinant IgE for cancer immunotherapy and AllergoOncology.

scientific article published on 19 January 2018

Epidemiological associations of allergy, IgE and cancer.

scientific article published on October 2013

Epinephrine drives human M2a allergic macrophages to a regulatory phenotype reducing mast cell degranulation in vitro

scientific article published on 04 April 2020

Filling the Antibody Pipeline in Allergy: PIPE Cloning of IgE, IgG1 and IgG4 against the Major Birch Pollen Allergen Bet v 1

scientific article published on 08 August 2020

IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype

scientific article published on 15 November 2020

IgE Antibodies against Cancer: Efficacy and Safety

scientific article published on 16 October 2020

IgE Antibodies: From Structure to Function and Clinical Translation

scientific article published on 22 February 2019

IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural states

scientific article published on 05 April 2019

IgE-antibody-dependent immunotherapy of solid tumors: cytotoxic and phagocytic mechanisms of eradication of ovarian cancer cells.

scientific article published on September 2007

Immune mediator expression signatures are associated with improved outcome in ovarian carcinoma

scientific article published on 28 March 2019

Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and Treatment

scientific article

Immunoglobulin E and cancer: a meta-analysis and a large Swedish cohort study

scientific article published on 9 June 2010

In Planta Glycan Engineering and Functional Activities of IgE Antibodies

scientific article published on 25 September 2019

In vivo safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model

scientific article published on 01 January 2020

Investigating the association between allergen-specific immunoglobulin E, cancer risk and survival

scientific article

Is There a Role for Exercise When Treating Patients with Cancer with Immune Checkpoint Inhibitors? A Scoping Review

scientific article published in 2022

Mechanisms of checkpoint inhibition-induced adverse events

scientific article published on 28 January 2020

Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies

scientific article (publication date: 2011)

Near infrared photoimmunotherapy targeting bladder cancer with a canine anti-epidermal growth factor receptor (EGFR) antibody.

scientific article published on 10 April 2018

PIPE-cloned human IgE and IgG4 antibodies: New tools for investigating cow's milk allergy and tolerance

scientific article published on 29 September 2020

Potential for monocyte recruitment by IgE immunotherapy for cancer in a rat model of tumour metastasis

scientific article published in The Lancet

Recombinant plant-derived human IgE glycoproteomics

scientific article published on 8 April 2017

Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation

scientific article

Revisiting the role of B cells in skin immune surveillance.

scientific article

Role of IgE receptors in IgE antibody-dependent cytotoxicity and phagocytosis of ovarian tumor cells by human monocytic cells.

scientific article

Targeting folate receptor alpha for cancer treatment

scientific article

The Role of IgG4 in the Fine Tuning of Tolerance in IgE-Mediated Allergy and Cancer

scientific article published on 16 July 2020

Therapeutic IgE Antibodies: Harnessing a Macrophage-Mediated Immune Surveillance Mechanism against Cancer.

scientific article

Therapeutic targets and new directions for antibodies developed for ovarian cancer.

scientific article published on 05 August 2016

Toward prediction of immune mechanisms and design of immunotherapies in melanoma

scientific article published on January 2012

Tumour-associated macrophage polarisation and re-education with immunotherapy

scientific article published on January 2015

WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion

scientific article published on 20 October 2020

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