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List of works by Grzegorz Dubin

1,4,5-Trisubstituted Imidazole-Based p53-MDM2/MDMX Antagonists with Aliphatic Linkers for Conjugation with Biological Carriers.

scientific article

1H, 15N and 13C NMR resonance assignments of staphostatin A, a specific Staphylococcus aureus cysteine proteinase inhibitor

scientific article published in March 2004

A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction

scientific article

A fluorinated indole-based MDM2 antagonist selectively inhibits the growth of p53wt osteosarcoma cells

scientific article published on 16 February 2019

A novel class of cysteine protease inhibitors: solution structure of staphostatin A from Staphylococcus aureus

scientific article

A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037

scientific article

A novel, dual pan-PIM/FLT3 inhibitor SEL24 exhibits broad therapeutic potential in acute myeloid leukemia.

scientific article published on 30 March 2018

A real-time cell-binding assay reveals dynamic features of STxB-Gb3 co-internalization and STxB-mediated cargo delivery into cancer cells

scientific article published on 30 May 2020

A regulatory role for Staphylococcus aureus toxin-antitoxin system PemIKSa

scientific article published in January 2013

A systematic investigation of the stability of green fluorescent protein fusion proteins

scientific article published on 21 July 2015

Activation mechanism of thiol protease precursor from broiler chicken specific Staphylococcus aureus strain CH-91.

scientific article

Adenoviral gene delivery to primary human cutaneous cells and burn wounds

scientific article published in September 2006

Anti-CD44 DNA Aptamers Selectively Target Cancer Cells

scientific article published on 06 May 2020

Application of Two-Dimensional Difference Gel Electrophoresis in Identification of Factors Responsible for Virulence of Staphylococcus aureus

scientific article published on 01 January 2020

Atomic resolution crystal structure of HV-BBI protease inhibitor from amphibian skin in complex with bovine trypsin

scientific article

Bacterial proteases in disease - role in intracellular survival, evasion of coagulation/ fibrinolysis innate defenses, toxicoses and viral infections

scientific article published on January 2013

Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.

scientific article

Biochemical and structural characterization of SplD protease from Staphylococcus aureus

scientific article

Characterisation of a highly specific, endogenous inhibitor of cysteine protease from Staphylococcus epidermidis, a new member of the staphostatin family

scientific article published in June 2004

Chromosomal localization of PemIK toxin-antitoxin system results in the loss of toxicity - Characterization of pemIKSa1-Sp from Staphylococcus pseudintermedius

scientific article published on 21 June 2020

Correction: Properties of halogenated and sulfonated porphyrins relevant for the selection of photosensitizers in anticancer and antimicrobial therapies

scientific article

Crystal Structure of Kluyveromyces lactis Glucokinase (KlGlk1)

scientific article published on 28 September 2019

Crystal Structure of Mannose Specific IIA Subunit of Phosphotransferase System from Streptococcus pneumoniae

scientific article published on 12 October 2020

Crystal structure of ADP-dependent glucokinase from Methanocaldococcus jannaschii in complex with 5-iodotubercidin reveals phosphoryl transfer mechanism

scientific article published on 20 January 2018

Crystal structure of Maternal Embryonic Leucine Zipper Kinase (MELK) in complex with dorsomorphin (Compound C)

scientific article published on 17 May 2019

Crystal structure of a low molecular weight activator Blm-pep with yeast 20S proteasome - insights into the enzyme activation mechanism

scientific article published on 21 July 2017

Crystal structure of the FAS1 domain of the hyaluronic acid receptor stabilin-2

scientific article published on 27 June 2018

DYRK1A Kinase Inhibitors Promote β-Cell Survival and Insulin Homeostasis

scientific article published on 31 August 2021

Defense against own arms: staphylococcal cysteine proteases and their inhibitors

scientific article published on January 1, 2003

Development and binding characteristics of phosphonate inhibitors of SplA protease from Staphylococcus aureus

scientific article

Development and characterization of a new inhibitor of heme oxygenase activity for cancer treatment

scientific article published on 02 July 2019

Development of Chemical Tools to Monitor Human Kallikrein 13 (KLK13) Activity ⬇️

article

Development of a novel, high-affinity ssDNA trypsin inhibitor

article

Distinct 3D Architecture and Dynamics of the Human HtrA2(Omi) Protease and Its Mutated Variants

scientific article

Distinct sequence and structural feature of trypanosoma malate dehydrogenase

scientific article published in June 2021

Elafin is specifically inactivated by RgpB from Porphyromonas gingivalis by distinct proteolytic cleavage

scientific article published on December 2009

Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln

scientific article

Evaluation of P1' substrate specificity of staphylococcal SplB protease.

scientific article

Exfoliative Toxins of Staphylococcus aureus ⬇️

scientific article published on May 25, 2010

Extracellular proteases of Staphylococcus spp.

scientific article

Functional and structural characterization of Spl proteases from Staphylococcus aureus

scientific article published on 13 February 2006

High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx

scientific article published on 16 April 2009

Identification of Secreted Exoproteome Fingerprints of Highly-Virulent and Non-Virulent Staphylococcus aureus Strains.

scientific article published on 06 May 2016

Identification of novel mazEF/pemIK family toxin-antitoxin loci and their distribution in the Staphylococcus genus

scientific article published on 18 October 2017

Identification of small-molecule inhibitors of USP2a

scientific article published on 5 March 2018

Inhibitors of programmed cell death 1 (PD-1): a patent review (2010-2015).

scientific article published on July 2016

Insights into eukaryotic Rubisco assembly - crystal structures of RbcX chaperones from Arabidopsis thaliana

scientific article

Interaction of regulators Mdm2 and Mdmx with transcription factors p53, p63 and p73.

scientific article published on 15 November 2010

Investigation of Serine-Proteinase-Catalyzed Peptide Splicing in Analogues of Sunflower Trypsin Inhibitor 1 (SFTI-1)

scientific article

Isolation, Identification, and Bioinformatic Analysis of Antibacterial Proteins and Peptides from Immunized Hemolymph of Red Palm Weevil

scientific article

Isolation, biochemical characterization, and cloning of a bacteriocin from the poultry-associated Staphylococcus aureus strain CH-91.

scientific article

Joint Genomic and Proteomic Analysis Identifies Meta-Trait Characteristics of Virulent and Non-virulent Staphylococcus aureus Strains.

scholarly article by Emilia A Bonar et al published 2018 in Frontiers in cellular and infection microbiology

Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)-A CleavEx Based Analysis

scientific article published on 19 June 2020

Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a

scientific article

Macrocyclic Peptide Inhibitor of PD‐1/PD‐L1 Immune Checkpoint

scientific article published on 18 November 2020

Malassezia globosa MgMDL2 lipase: Crystal structure and rational modification of substrate specificity

scientific article published on 19 April 2017

Mdm2 and MdmX inhibitors for the treatment of cancer: a patent review (2011-present).

scientific article published on 04 February 2013

Mechanism of MyD88S mediated signal termination

scientific article published on 20 January 2022

Modular endolysin of Burkholderia AP3 phage has the largest lysozyme-like catalytic subunit discovered to date and no catalytic aspartate residue

scientific article published on 6 November 2017

New generation of peptide antibiotics.

scientific article

On the mechanism of action of SJ-172550 in inhibiting the interaction of MDM4 and p53

scientific article

Photoinactivation of microorganisms with sub-micromolar concentrations of imidazolium metallophthalocyanine salts

scientific article published on 28 September 2019

Prevalence of genes encoding extracellular proteases in Staphylococcus aureus - important targets triggering immune response in vivo.

scientific article

Production of Lysostaphin by Nonproprietary Method Utilizing a Promoter from Toxin-Antitoxin System

scientific article published on 01 October 2019

Properties of halogenated and sulfonated porphyrins relevant for the selection of photosensitizers in anticancer and antimicrobial therapies

scientific article published on 10 October 2017

Rational design and synthesis of 1,5-disubstituted tetrazoles as potent inhibitors of the MDM2-p53 interaction.

scientific article published on 16 November 2016

Sensitization of TiO2 by halogenated porphyrin derivatives for visible light biomedical and environmental photocatalysis

scientific article published in September 2019

Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1.

scientific article published on 14 June 2017

Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells.

scientific article published on 7 August 2017

Spatial attributes of the four-helix bundle group of bacteriocins - The high-resolution structure of BacSp222 in solution

scientific article published on 26 October 2017

Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation

scientific article

Staphylococcal proteases aid evasion of human complement system

scientific article published in November 2012

Staphylococcal proteases aid in evasion of the human complement system

scientific article

Staphylococcus Aureus V8 protease disrupts the integrity of the airway epithelial barrier and impairs IL-6 production in vitro.

scientific article

Staphylococcus aureus infection triggers production of neutralizing, V8 protease-specific antibodies

scientific article published on 16 January 2008

Staphylococcus aureus-derived staphopain B, a potent cysteine protease activator of plasma chemerin

scientific article published in March 2007

Structural Basis of GD2 Ganglioside and Mimetic Peptide Recognition by 14G2a Antibody.

scientific article

Structural Biology of the Immune Checkpoint Receptor PD-1 and Its Ligands PD-L1/PD-L2.

scientific article published in August 2017

Structural Characterization of Glycerol Kinase from the Thermophilic Fungus <i>Chaetomium thermophilum</i>

scientific article published on 16 December 2020

Structural Characterization of Human Coronavirus NL63 N Protein

scientific article published on 22 March 2017

Structural Characterization of a Macrocyclic Peptide Modulator of the PD-1/PD-L1 Immune Checkpoint Axis

scientific article published on 11 August 2021

Structural Determinants of Substrate Specificity of SplF Protease from

scientific article published on 23 February 2021

Structural analysis of PIM1 kinase complexes with ATP-competitive inhibitors

scientific article published on 17 October 2017

Structural and functional characterization of SplA, an exclusively specific protease of Staphylococcus aureus

scientific article

Structural basis for ADP-dependent glucokinase inhibition by 8-bromo-substituted adenosine nucleotide

scientific article published on 21 May 2018

Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)

scientific article (publication date: 24 May 2016)

Structural phase transition and related electronic properties in quasi-one-dimensional (NbSe4)(10/3)I.

scientific article published on 17 May 2013

Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1.

scientific article published on 22 October 2015

Structure, Biosynthesis, and Biological Activity of Succinylated Forms of Bacteriocin BacSp222

scientific article published on 10 June 2021

Structure-Activity Relationship in Pyrazolo[4,3-c]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity

scientific article published on 06 January 2020

Substrate specificity of Staphylococcus aureus cysteine proteases--Staphopains A, B and C.

scientific article

Surface Modification of Nanocrystalline TiO2 Materials with Sulfonated Porphyrins for Visible Light Antimicrobial Therapy

scientific article published on 29 September 2019

The human fibrinolytic system is a target for the staphylococcal metalloprotease aureolysin

scientific article published on February 2008

The nucleocapsid protein of human coronavirus NL63

scientific article

The outer-membrane export signal of Porphyromonas gingivalis type IX secretion system (T9SS) is a conserved C-terminal β-sandwich domain

scientific article published on 23 March 2016

The staphostatin family of cysteine protease inhibitors in the genus Staphylococcus as an example of parallel evolution of protease and inhibitor specificity.

scientific article published in February 2007

The virulence of Staphylococcus aureus correlates with strain genotype in a chicken embryo model but not a nematode model.

scientific article published on 4 October 2012

Ultrasensitive electrochemical determination of the cancer biomarker protein sPD-L1 based on a BMS-8-modified gold electrode

scientific article published in June 2021

Unique Substrate Specificity of SplE Serine Protease from Staphylococcus aureus

scientific article published in March 2018

Visualization of kallikreins in thyroid epithelial and carcinoma cells

scholarly article by Eileen Kroll et al published 13 May 2016 in Endocrine Abstracts

Water envelope has a critical impact on the design of protein-protein interaction inhibitors

scientific article published on 20 March 2020

α1-Antichymotrypsin inactivates staphylococcal cysteine protease in cross-class inhibition

scientific article published on 3 February 2011

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