List of works - Bogdan A. Solaja

4-Amino-7-chloroquinolines: probing ligand efficiency provides botulinum neurotoxin serotype A light chain inhibitors with significant antiprotozoal activity

scientific article published on 12 July 2013

4-Aminoquinoline-based compounds as antileishmanial agents that inhibit the energy metabolism of Leishmania

scientific article published on 05 July 2019

A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus.

scientific article

A limited structural modification results in a significantly more efficacious diazachrysene-based filovirus inhibitor

scientific article

A refined pharmacophore identifies potent 4-amino-7-chloroquinoline-based inhibitors of the botulinum neurotoxin serotype A metalloprotease

scientific article published on 07 April 2007

Anti-Ebola Activity of Diazachrysene Small Molecules.

scientific article published on 4 May 2015

Antimalarial and antiproliferative evaluation of bis-steroidal tetraoxanes

scientific article published on July 2003

Antimalarial, antimycobacterial and antiproliferative activity of phenyl substituted mixed tetraoxanes

Antimalarials with Benzothiophene Moieties as Aminoquinoline Partners.

scientific article published on 24 February 2017

Benzothiazole carbamates and amides as antiproliferative species

scientific article published on 29 August 2018

Cholic acid derivatives as 1,2,4,5-tetraoxane carriers: structure and antimalarial and antiproliferative activity.

scientific article published on August 2000

Correlation between structure, retention and activity of cholic acid derived cis-trans isomeric bis-steroidal tetraoxanes.

scientific article

Correlation between structure, retention, property, and activity of biologically relevant 1,7-bis(aminoalkyl)diazachrysene derivatives.

scientific article published on 27 August 2012

Correlation study of retention data and antimalarial activity of 1,2,4,5-mixed tetraoxanes with their molecular structure descriptors and LSER parameters.

scientific article

Deoxycholic acid-derived tetraoxane antimalarials and antiproliferatives(1).

scientific article published on 21 September 2007

Examination of the antimalarial potential of experimental aminoquinolines: poor in vitro effect does not preclude in vivo efficacy.

scientific article published on 28 June 2017

Human serum albumin binding of certain antimalarials.

scientific article

Investigation into novel thiophene- and furan-based 4-amino-7-chloroquinolines afforded antimalarials that cure mice

scientific article published on 7 March 2015

Mixed steroidal 1,2,4,5-tetraoxanes: antimalarial and antimycobacterial activity

scientific article published on August 2002

Mixed steroidal tetraoxanes induce apoptotic cell death in tumor cells

scientific article published on 15 November 2008

Mixed tetraoxanes containing the acetone subunit as antimalarials

scientific article published on 10 May 2008

New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Post-intoxication Model.

scientific article published on 31 January 2018

New chimeric antimalarials with 4-aminoquinoline moiety linked to a tetraoxane skeleton

scientific article published on 6 September 2008

Novel 4-aminoquinolines active against chloroquine-resistant and sensitive P. falciparum strains that also inhibit botulinum serotype A.

scientific article published on 19 July 2008

Novel Aminoquinoline Derivatives Significantly Reduce Parasite Load in Leishmania infantum Infected Mice

scientific article published on 04 May 2018

Oxidation of steroidal 5-en-3 beta-ols with Jones reagent in ether.

scientific article published in May 1994

Protein covalent modification of biologically active quinones

Quantitative structure retention/activity relationships of biologically relevant 4-amino-7-chloroquinoline based compounds

scientific article published on 22 January 2016

Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials?

scientific article

Second generation steroidal 4-aminoquinolines are potent, dual-target inhibitors of the botulinum neurotoxin serotype A metalloprotease and P. falciparum malaria

scientific article

Steroidal geminal dihydroperoxides and 1,2,4,5-tetraoxanes: structure determination and their antimalarial activity

scientific article published in December 1996

Synthesis and anti-Candida activity of novel benzothiepino[3,2-c]pyridine derivatives.

scientific article published on 18 June 2016

Synthesis and antiproliferative activity of A-ring aromatised and conduritol-like steroidal compounds.

scientific article published on September 2005

Synthesis and antiproliferative activity of epoxy and bromo compounds derived from estrone

scientific article published in August 2001

Synthesis and evaluation of thiophene-based guanylhydrazones (iminoguanidines) efficient against panel of voriconazole-resistant fungal isolates

scientific article published on 2 February 2016

Tetraoxane antimalarials and their reaction with Fe(II).

scientific article published on June 2006

The synthesis and in vitro activity of some delta 7,9(11)-lanostadienes

scientific article published on 01 November 1997

The synthesis of 2,5-bis(4-amidinophenyl)thiophene derivatives providing submicromolar-range inhibition of the botulinum neurotoxin serotype A metalloprotease

scientific article

Three-dimensional database mining identifies a unique chemotype that unites structurally diverse botulinum neurotoxin serotype A inhibitors in a three-zone pharmacophore.

scientific article published in December 2008

List of works by Bogdan A. Solaja

4-Amino-7-chloroquinolines: probing ligand efficiency provides botulinum neurotoxin serotype A light chain inhibitors with significant antiprotozoal activity

4-Aminoquinoline-based compounds as antileishmanial agents that inhibit the energy metabolism of Leishmania

A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus.

A limited structural modification results in a significantly more efficacious diazachrysene-based filovirus inhibitor

A refined pharmacophore identifies potent 4-amino-7-chloroquinoline-based inhibitors of the botulinum neurotoxin serotype A metalloprotease

Anti-Ebola Activity of Diazachrysene Small Molecules.

Antimalarial and antiproliferative evaluation of bis-steroidal tetraoxanes

Antimalarial, antimycobacterial and antiproliferative activity of phenyl substituted mixed tetraoxanes

Antimalarials with Benzothiophene Moieties as Aminoquinoline Partners.

Benzothiazole carbamates and amides as antiproliferative species

Cholic acid derivatives as 1,2,4,5-tetraoxane carriers: structure and antimalarial and antiproliferative activity.

Correlation between structure, retention and activity of cholic acid derived cis-trans isomeric bis-steroidal tetraoxanes.

Correlation between structure, retention, property, and activity of biologically relevant 1,7-bis(aminoalkyl)diazachrysene derivatives.

Correlation study of retention data and antimalarial activity of 1,2,4,5-mixed tetraoxanes with their molecular structure descriptors and LSER parameters.

Deoxycholic acid-derived tetraoxane antimalarials and antiproliferatives(1).

Examination of the antimalarial potential of experimental aminoquinolines: poor in vitro effect does not preclude in vivo efficacy.

Human serum albumin binding of certain antimalarials.

Investigation into novel thiophene- and furan-based 4-amino-7-chloroquinolines afforded antimalarials that cure mice

Mixed steroidal 1,2,4,5-tetraoxanes: antimalarial and antimycobacterial activity

Mixed steroidal tetraoxanes induce apoptotic cell death in tumor cells

Mixed tetraoxanes containing the acetone subunit as antimalarials

New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Post-intoxication Model.

New chimeric antimalarials with 4-aminoquinoline moiety linked to a tetraoxane skeleton

Novel 4-aminoquinolines active against chloroquine-resistant and sensitive P. falciparum strains that also inhibit botulinum serotype A.

Novel Aminoquinoline Derivatives Significantly Reduce Parasite Load in Leishmania infantum Infected Mice

Oxidation of steroidal 5-en-3 beta-ols with Jones reagent in ether.

Protein covalent modification of biologically active quinones

Quantitative structure retention/activity relationships of biologically relevant 4-amino-7-chloroquinoline based compounds

Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials?

Second generation steroidal 4-aminoquinolines are potent, dual-target inhibitors of the botulinum neurotoxin serotype A metalloprotease and P. falciparum malaria

Steroidal geminal dihydroperoxides and 1,2,4,5-tetraoxanes: structure determination and their antimalarial activity

Synthesis and anti-Candida activity of novel benzothiepino[3,2-c]pyridine derivatives.

Synthesis and antiproliferative activity of A-ring aromatised and conduritol-like steroidal compounds.

Synthesis and antiproliferative activity of epoxy and bromo compounds derived from estrone

Synthesis and evaluation of thiophene-based guanylhydrazones (iminoguanidines) efficient against panel of voriconazole-resistant fungal isolates

Tetraoxane antimalarials and their reaction with Fe(II).

The synthesis and in vitro activity of some delta 7,9(11)-lanostadienes

The synthesis of 2,5-bis(4-amidinophenyl)thiophene derivatives providing submicromolar-range inhibition of the botulinum neurotoxin serotype A metalloprotease

Three-dimensional database mining identifies a unique chemotype that unites structurally diverse botulinum neurotoxin serotype A inhibitors in a three-zone pharmacophore.