Search filters

List of works by Thomas Karn

"Stem cell like" breast cancers-a model for the identification of new prognostic/predictive markers in endocrine responsive breast cancer exemplified by Plexin B1

scientific article published on 15 April 2008

A Comprehensive Analysis of Human Gene Expression Profiles Identifies Stromal Immunoglobulin C as a Compatible Prognostic Marker in Human Solid Tumors

article

A Small Hypoxia Signature Predicted pCR Response to Bevacizumab in the Neoadjuvant GeparQuinto Breast Cancer Trial

scientific article published on 13 January 2020

A clinically relevant gene signature in triple negative and basal-like breast cancer

scientific article published on 6 October 2011

Acid ceramidase (AC)--a key enzyme of sphingolipid metabolism--correlates with better prognosis in epithelial ovarian cancer

scientific article published on 01 May 2013

Acid ceramidase 1 expression correlates with a better prognosis in ER-positive breast cancer

scientific article published in December 2009

Acid ceramidase is associated with an improved prognosis in both DCIS and invasive breast cancer.

scientific article published on 31 July 2014

Androgen receptor expression and response to chemotherapy in breast cancer patients treated in the neoadjuvant TECHNO and PREPARE trial

scientific article published on 15 November 2019

Androgen receptor expression is a predictive marker in chemotherapy-treated patients with endocrine receptor-positive primary breast cancers.

scientific article

Association Between Genomic Metrics and Immune Infiltration in Triple-Negative Breast Cancer

scientific article

Breast Cancer Proteomics - Differences in Protein Expression between Estrogen Receptor-Positive and -Negative Tumors Identified by Tandem Mass Tag Technology

scientific article

C-KIT expression in ductal carcinoma in situ of the breast: co-expression with HER-2/neu

scientific article published in February 2006

CD73 is associated with poor prognosis in high-grade serous ovarian cancer

scientific article published on 11 September 2015

Catheter-related Complications of Subcutaneous Implantable Venous Access Devices in Breast Cancer Patients

scientific article

Characterization of WNT7A expression in human endometrium and endometriotic lesions

scientific article

Characterization of the human CSK locus

scientific article published on 01 May 1993

Claudin-1 expression in cervical cancer.

scientific article published on 25 August 2017

Claudin-1 is linked to presence of implants and micropapillary pattern in serous borderline epithelial tumours of the ovary

scientific article published on 31 August 2018

Clinical Relevance of Collagen Protein Degradation Markers C3M and C4M in the Serum of Breast Cancer Patients Treated with Neoadjuvant Therapy in the GeparQuinto Trial

scientific article published on 15 August 2019

Clinical relevance of the putative stem cell marker p63 in breast cancer

scientific article published on 7 November 2009

Control of dataset bias in combined Affymetrix cohorts of triple negative breast cancer

scientific article

Controversies concerning the use of neoadjuvant systemic therapy for primary breast cancer

scientific article published on 01 July 2012

Correction: The lipid-transfer protein Nir2 enhances epithelial-mesenchymal transition and facilitates breast cancer metastasis (doi:10.1242/jcs.155721)

scientific article published on 07 March 2019

Data-driven derivation of cutoffs from a pool of 3,030 Affymetrix arrays to stratify distinct clinical types of breast cancer

scientific article

Differential effect on different immune subsets of neoadjuvant chemotherapy in patients with TNBC

scientific article published on 01 November 2020

Differential expression of claudins in human endometrium and endometriosis

scientific article published on 01 August 2008

Differentially expressed genes of reprogrammed human pluripotent stem cells in breast cancer

scientific article published on 06 August 2008

Dynamic classification using case-specific training cohorts outperforms static gene expression signatures in breast cancer.

scientific article

Evaluation of soluble carbonic anhydrase IX as predictive marker for efficacy of bevacizumab: A biomarker analysis from the geparquinto phase III neoadjuvant breast cancer trial

scientific article published on 04 March 2019

Expression of membrane-type 5 matrix metalloproteinase in human endometrium and endometriosis

scientific article

Expression of secreted protein acidic and rich in cysteine (SPARC) in breast cancer and response to neoadjuvant chemotherapy

scientific article published on 29 October 2014

Fascin-1 expression as stratification marker in borderline epithelial tumours of the ovary

scientific article published on 11 September 2015

Gene expression of ceramide kinase, galactosyl ceramide synthase and ganglioside GD3 synthase is associated with prognosis in breast cancer

scientific article

Gene expression of topoisomerase II alpha (TOP2A) by microarray analysis is highly prognostic in estrogen receptor (ER) positive breast cancer

scientific article published on 14 March 2008

Gene expression profiles of breast cancer obtained from core cut biopsies before neoadjuvant docetaxel, adriamycin, and cyclophoshamide chemotherapy correlate with routine prognostic markers and could be used to identify predictive signatures

scientific article published on 01 April 2006

Gene expression profiling of luminal B breast cancers reveals NHERF1 as a new marker of endocrine resistance

scientific article published on 04 January 2011

Genomic predictor of residual risk of recurrence after adjuvant chemotherapy and endocrine therapy in high risk estrogen receptor-positive breast cancers.

scientific article published on 5 February 2015

High-throughput gene expression and mutation profiling: current methods and future perspectives.

scientific article published on December 2013

Histotype-specific analysis of acid ceramidase expression in ovarian cancer

scientific article published on 02 January 2020

Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures

scientific article

Human SAK related to the PLK/polo family of cell cycle kinases shows high mRNA expression in testis.

scientific article published in May 1997

Human and Xenopus mo15 messenger-RNA are highly conserved but show different patterns of expression in adult tissues ⬇️

scientific article published on November 1, 1994

Human leucocyte antigen class I in hormone receptor-positive, HER2-negative breast cancer: association with response and survival after neoadjuvant chemotherapy

scientific article published on 11 December 2019

IMP3 Expression in Borderline Tumors of the Ovary

scientific article published in February 2017

Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer

scientific article published on 17 October 2019

Identification of preeclampsia by cDNA-gene expression profiling in human placentas and serum -- a pilot study

scientific article published in June 2006

Immune Gene Expression Is Associated with Genomic Aberrations in Breast Cancer

scientific article published on 20 April 2017

Impact of re-excision of residual adjacent vulvar intraepithelial neoplasia (VIN III) and histological tumour-free margin (hTFM) on survival in primary squamous cell carcinoma of vulva

scientific article published on 06 September 2018

Ki67 measured after neoadjuvant chemotherapy for primary breast cancer

scientific article

Loss of Plexin B1 is highly prognostic in low proliferating ER positive breast cancers--results of a large scale microarray analysis

scientific article published on 04 December 2008

Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation

scientific article

Methylation of estrogen receptor beta promoter correlates with loss of ER-beta expression in mammary carcinoma and is an early indication marker in premalignant lesions

scientific article published on 01 December 2005

Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer.

scientific article published on 4 December 2007

Molecular Markers as Prognostic Factors in DCIS and Small Invasive Breast Cancers

scientific article

Molecular classification of breast cancer patients by gene expression profiling* ⬇️

scientific article published on October 1, 2001

Mutational Diversity and Therapy Response in Breast Cancer: A Sequencing Analysis in the Neoadjuvant GeparSepto Trial

scientific article published on 12 April 2019

Nef proteins of distinct HIV-1 or -2 isolates differ in their binding properties for HCK: isolation of a novel Nef binding factor with characteristics of an adaptor protein.

scientific article

New Strategies in Breast Cancer: Immunotherapy.

scientific article

OPG and PgR show similar cohort specific effects as prognostic factors in ER positive breast cancer

scientific article published on 15 April 2014

Oncogenic alterations in primary human lung-tumors (review)

scientific article published on January 1, 1994

Outcome after neoadjuvant chemotherapy in estrogen receptor-positive and progesterone receptor-negative breast cancer patients: a pooled analysis of individual patient data from ten prospectively randomized controlled neoadjuvant trials

scientific article published on 5 September 2017

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor ⬇️

scientific article published on August 18, 1998

PYK2 sustains endosomal-derived receptor signalling and enhances epithelial-to-mesenchymal transition.

scientific article

Poor outcome in estrogen receptor-positive breast cancers predicted by loss of plexin B1

scientific article published on 01 February 2007

Predictive value of sphingosine kinase 1 expression in neoadjuvant treatment of breast cancer

scientific article

Prognostic evaluation of the B cell/IL-8 metagene in different intrinsic breast cancer subtypes

scientific article

Prognostic impact of fascin-1 (FSCN1) in epithelial ovarian cancer

scientific article

Prognostic impact of thymidine phosphorylase expression in breast cancer--comparison of microarray and immunohistochemical data

scientific article

Prognostic relevance of glucosylceramide synthase (GCS) expression in breast cancer

scientific article published on 17 June 2008

Prognostic relevance of glycosylation-associated genes in breast cancer

scientific article published on 16 April 2014

Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers

scientific article published on January 2013

Quantitative analysis of the sHLA-G protein in seminal plasma

scientific article published on 10 June 2019

Recommendations from an international consensus conference on the current status and future of neoadjuvant systemic therapy in primary breast cancer.

scientific article published on 23 December 2011

Relevance of cellular and serum carbonic anhydrase IX in primary breast cancer

scientific article

Relevance of tumour-infiltrating lymphocytes, PD-1 and PD-L1 in patients with high-risk, nodal-metastasised breast cancer of the German Adjuvant Intergroup Node-positive study

scientific article published on 07 May 2019

SATB1 gene expression and breast cancer prognosis ⬇️

scientific article published on October 25, 2010

Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial

scientific article published on 10 October 2018

Structure, expression and chromosomal mapping of TKT from man and mouse: a new subclass of receptor tyrosine kinases with a factor VIII-like domain

scientific article (publication date: December 1993)

Subtype-Specific Metagene-Based Prediction of Outcome after Neoadjuvant and Adjuvant Treatment in Breast Cancer.

scientific article

Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosis

scientific article published on 21 August 2020

T-cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers.

scientific article published on 09 March 2009

TFF3 Expression as Stratification Marker in Borderline Epithelial Tumors of the Ovary

scientific article published on 3 May 2017

Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4-NDRG1 Axis

scientific article

The Influence of Host Factors on the Prognosis of Breast Cancer: Stroma and Immune Cell Components as Cancer Biomarkers

scientific article published on January 2015

The lipid-transfer protein Nir2 enhances epithelial-mesenchymal transition and facilitates breast cancer metastasis

scientific article published on September 2014

The prognostic impact of age in different molecular subtypes of breast cancer

scientific article published on 21 July 2015

The prognostic impact of age in patients with triple-negative breast cancer

scientific article published on 5 March 2013

The role of genetic breast cancer susceptibility variants as prognostic factors

scientific article

Thymosin beta 15A (TMSB15A) is a predictor of chemotherapy response in triple-negative breast cancer ⬇️

scientific article published on October 18, 2012

Trefoil factor 3 expression in epithelial ovarian cancer exerts a minor effect on clinicopathological parameters.

scientific article published on 17 August 2016

Tyrosine-614, the major autophosphorylation site of the receptor tyrosine kinase HEK2, functions as multi-docking site for SH2-domain mediated interactions

scientific article

Validity of the proliferation markers Ki67, TOP2A, and RacGAP1 in molecular subgroups of breast cancer

scientific article

Paulina is supported by:

About Paulina

Help