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List of works by Daniel P Cahill

-OMICS AND PROGNOSTIC MARKERS

scientific article published on 21 October 2011

3 Tesla intraoperative MRI for brain tumor surgery

scientific article

A new patient-derived orthotopic malignant meningioma model treated with oncolytic herpes simplex virus.

scientific article published on 6 March 2016

AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

scientific article

Absence of IDH1-R132H mutation predicts rapid progression of nonenhancing diffuse glioma in older adults.

scientific article published on 24 December 2011

Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.

scientific article published on 2 December 2016

BM-07GENOMIC CHARACTERIZATION OF BRAIN METASTASES REVEALS BRANCHED EVOLUTION AND METASTASIS-SPECIFIC MUTATIONS

Butterfly glioblastomas: a retrospective review and qualitative assessment of outcomes.

scientific article published on 18 July 2012

Carcinogen-specific induction of genetic instability.

scholarly article

Case 38-2016. A 52-Year-Old Woman with Recurrent Oligodendroglioma

scientific article published in December 2016

Case records of the Massachusetts General Hospital. Case 10-2010. A 37-year-old woman with weakness and a mass in the brain

scientific article published in April 2010

Clinical and radiographic response following targeting of BCAN-NTRK1 fusion in glioneuronal tumor.

scientific article published on 20 March 2017

Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma.

scientific article

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq.

scientific article published on March 2017

Defining Glioblastoma Resectability Through the Wisdom of the Crowd: A Proof-of-Principle Study.

scientific article published on 4 August 2016

Detection of oncogenic IDH1 mutations using magnetic resonance spectroscopy of 2-hydroxyglutarate

scientific article

Detection of wild-type EGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients

scientific article

Determining optimal treatment strategy for diffuse glioma: the emerging role of IDH mutations.

scientific article published on 17 May 2015

Diagnosis and management of craniopharyngiomas in the era of genomics and targeted therapy.

scientific article published on December 2016

Diagnostic discrepancies in malignant astrocytoma due to limited small pathological tumor sample can be overcome by IDH1 testing

scientific article

Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy.

scientific article published on 23 October 2015

Elevation of Urinary 2-Hydroxyglutarate in IDH-Mutant Glioma

scientific article published on February 2016

Evolution of delayed resistance to immunotherapy in a melanoma responder

scientific article published on 03 May 2021

Exploring Predictors of Response to Dacomitinib in EGFR-Amplified Recurrent Glioblastoma

scientific article published on 08 June 2020

Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion.

scientific article

From genomics to the clinic: biological and translational insights of mutant IDH1/2 in glioma.

scientific article published on February 2013

Genetic instability and darwinian selection in tumours

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

scientific article published on 26 September 2015

Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

scientific article published on 12 October 2021

Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma

scientific article published on 23 March 2020

Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas

scientific article published on 9 November 2016

Glioblastoma care in the elderly.

scientific article

Glioma-Associated Cytomegalovirus Mediates Subversion of the Monocyte Lineage to a Tumor Propagating Phenotype ⬇️

scientific article published on April 13, 2011

IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II-III diffuse gliomas

scientific article

IDH1 Mutation and World Health Organization 2016 Diagnostic Criteria for Adult Diffuse Gliomas: Advances in Surgical Strategy.

scientific article published in September 2017

IDH1 mutant malignant astrocytomas are more amenable to surgical resection and have a survival benefit associated with maximal surgical resection

scientific article

Immunohistochemical detection of somatostatin receptor subtype 5 (SSTR-5) in cushing adenoma

scientific article published on 06 November 2009

Impact of histopathological transformation and overall survival in patients with progressive anaplastic glioma

scientific article published on 6 June 2016

Intratumoral heterogeneity and TERT promoter mutations in progressive/higher-grade meningiomas

scientific article

Ipilimumab and craniotomy in patients with melanoma and brain metastases: a case series.

scientific article

Isocitrate Dehydrogenase Mutations in Low-Grade Gliomas Correlate With Prolonged Overall Survival in Older Patients

scientific article published on 01 February 2019

Isocitrate dehydrogenase 1 R132H mutation is not detected in angiocentric glioma

scientific article published on 23 March 2012

Isocitrate dehydrogenase-mutant glioma: Evolving clinical and therapeutic implications.

scientific article

L265P mutation and loss are early mutational events in primary central nervous system diffuse large B-cell lymphomas

scientific article published on 01 February 2019

MSH6 inactivation and emergent temozolomide resistance in human glioblastomas

scientific article published in January 2008

MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance.

scientific article published on 07 July 2009

Malignant Melanoma Metastatic to Oligodendroglioma: Case Report and Literature Review of Tumor-to-Tumor Metastasis to Gliomas.

scientific article

Management of brain metastases in the era of targeted and immunomodulatory therapies

scientific article

Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma.

scientific article published on 29 August 2013

Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1.

scientific article

Molecular genetics of low-grade gliomas: genomic alterations guiding diagnosis and therapeutic intervention. 11th Annual Frye-Halloran Brain Tumor Symposium ⬇️

scientific article published on February 1, 2013

Molecular pathogenesis and therapeutic implications in pediatric high-grade gliomas

scientific article

Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma.

scientific article published in December 2011

Mutation Screening of the TNFRSF11A Gene Encoding Receptor Activator of NFkB (RANK) in Familial and Sporadic Paget's Disease of Bone and Osteosarcoma

article

Mutations in CIC and FUBP1 contribute to human oligodendroglioma

scientific article (publication date: 9 September 2011)

Mutations of mitotic checkpoint genes in human cancers ⬇️

scientific article published on March 19, 1998

Neural encoding and production of functional morphemes in the posterior temporal lobe.

scientific article

Neurocognitive function varies by IDH1 genetic mutation status in patients with malignant glioma prior to surgical resection

scientific article published on 30 August 2016

Origin of Gliomas.

scientific article

Outcomes for patients with anaplastic astrocytoma treated with chemoradiation, radiation therapy alone or radiation therapy followed by chemotherapy: a retrospective review within the era of temozolomide

scientific article published on 23 March 2013

Perspectives on investigational drugs and immunotherapies for glioblastoma

scientific article

Pharmacodynamics of mutant-IDH1 inhibitors in glioma patients probed by in vivo 3D MRS imaging of 2-hydroxyglutarate.

scientific article published on 16 April 2018

Phase 2 study of bosutinib, a Src inhibitor, in adults with recurrent glioblastoma.

scientific article

Post-operative stereotactic radiosurgery versus observation for completely resected brain metastases: a single-centre, randomised, controlled, phase 3 trial

scientific article

Predictors of survival in contemporary practice after initial radiosurgery for brain metastases.

scientific article published on 14 August 2012

Publisher Correction: Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis

scientific article published on 18 June 2020

Radiographic assessment of contrast enhancement and T2/FLAIR mismatch sign in lower grade gliomas: correlation with molecular groups

scientific article published on 07 December 2018

Rapid Intraoperative Molecular Characterization of Glioma

scientific article published on 14 May 2015

Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells

scientific article published on 10 April 2014

Reply to Freyschlag et al.

scientific article published in April 2017

Resolving the phylogenetic origin of glioblastoma via multifocal genomic analysis of pre-treatment and treatment-resistant autopsy specimens.

scientific article published on 18 September 2017

Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis

scientific article published on 01 June 2020

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

scientific article

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

scientific article published on 2 November 2016

Spatial Proximity to Fibroblasts Impacts Molecular Features and Therapeutic Sensitivity of Breast Cancer Cells Influencing Clinical Outcomes

scientific article published on 26 September 2016

Sporadic hemangioblastomas are characterized by cryptic VHL inactivation

scientific article

Super-Resolution Whole-Brain 3D MR Spectroscopic Imaging for Mapping D-2-Hydroxyglutarate and Tumor Metabolism in Isocitrate Dehydrogenase 1-mutated Human Gliomas

scientific article published on 07 January 2020

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate

scientific article published on 09 July 2018

Systemic therapy of brain metastases.

scientific article published on January 2015

Tailored therapy in diffuse gliomas: using molecular classifiers to optimize clinical management

scientific article published on June 1, 2013

Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas.

scientific article

Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas

scientific article published on 25 November 2016

The Alkylating Chemotherapeutic Temozolomide Induces Metabolic Stress in IDH1-Mutant Cancers and Potentiates NAD+ Depletion-Mediated Cytotoxicity

scientific article

The effect of IDH1 mutation on the structural connectome in malignant astrocytoma

scientific article published on 15 November 2016

The role of biopsy in the management of patients with presumed diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline

scientific article

The role of neuropathology in the management of patients with diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline

scientific article

Three classes of genes mutated in colorectal cancers with chromosomal instability

scientific article published in May 2004

Treatment Response Assessment in IDH-Mutant Glioma Patients by Noninvasive 3D Functional Spectroscopic Mapping of 2-Hydroxyglutarate.

scientific article published on 3 November 2015

Treatment of brain metastases in the modern genomic era.

scientific article

Unusual visual symptoms in a patient with bilateral vertebral artery dissection: a case report

scientific article published on 01 August 2006

Volumetric relationship between 2-hydroxyglutarate and FLAIR hyperintensity has potential implications for radiotherapy planning of mutant IDH glioma patients.

scientific article published on 5 July 2016

Where are we now? And where are we going? A report from the Accelerate Brain Cancer Cure (ABC2) low-grade glioma research workshop.

scientific article published on 04 December 2013

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