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List of works by Hamid I. Akbarali

6β-N-heterocyclic substituted naltrexamine derivative NAP as a potential lead to develop peripheral mu opioid receptor selective antagonists

scientific article

Acute colitis enhances responsiveness of lumbosacral spinal neurons to colorectal distension in rats

scientific article published on 08 May 2007

Altered gene expression and increased bursting activity of colonic smooth muscle ATP-sensitive K+ channels in experimental colitis

scientific article published on 12 February 2004

Altered ion channel activity in murine colonic smooth muscle myocytes in an experimental colitis model

scientific article published on 01 August 2000

Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice

scientific article

Brain-derived neurotrophic factor enhances cholinergic contraction of longitudinal muscle of rabbit intestine via activation of phospholipase C

scientific article published on 19 December 2013

Calcium carbonate antacids alter esophageal motility in heartburn sufferers

scientific article published in November 2004

Changes in urinary bladder smooth muscle function in response to colonic inflammation

scientific article published on 22 August 2007

Cloning and functional characterization of the smooth muscle ether-a-go-go-related gene K+ channel. Potential role of a conserved amino acid substitution in the S4 region

scientific article published on 9 November 2002

Colonic inflammation alters Src kinase-dependent gating properties of single Ca2+ channels via tyrosine nitration

scientific article published on 8 April 2010

Colonic inflammation increases Na+ currents in bladder sensory neurons

scientific article published in December 2004

Coupling of M2 muscarinic receptor to L-type Ca channel via c-src kinase in rabbit colonic circular smooth muscle

scientific article published on September 2002

Cross-organ sensitization of lumbosacral spinal neurons receiving urinary bladder input in rats with inflamed colon

scientific article published on 01 December 2005

Denitration of L-type calcium channel.

scientific article

Depletion of [Ca2+]i inhibits hypoxia-induced vascular permeability factor (vascular endothelial growth factor) gene expression

scientific article published on December 1996

Design, Synthesis, and Biological Evaluation of 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[(4′-pyridyl)carboxamido]morphinan Derivatives as Peripheral Selective μ Opioid Receptor Agents ⬇️

scientific article published on November 9, 2012

Differences in the characteristics of tolerance to μ-opioid receptor agonists in the colon from wild type and β-arrestin2 knockout mice

scientific article

Effects of HIV-1 Tat on enteric neuropathogenesis.

scientific article

Electrophysiological Characteristics of Enteric Neurons Isolated from the Immortomouse ⬇️

scientific article published on January 31, 2013

Evidence for the putative cannabinoid receptor (GPR55)-mediated inhibitory effects on intestinal contractility in mice.

scientific article published on 28 June 2012

Fenamate-induced enhancement of heterologously expressed HERG currents in Xenopus oocytes

scientific article published in October 2002

Gastrointestinal motility, dysbiosis and opioid-induced tolerance: is there a link?

scientific article published on 01 June 2019

Hydrogen Sulfide as an Allosteric Modulator of ATP-Sensitive Potassium Channels in Colonic Inflammation ⬇️

scientific article published on October 31, 2012

Hyperexcitability of convergent colon and bladder dorsal root ganglion neurons after colonic inflammation: mechanism for pelvic organ cross-talk

scientific article published in October 2006

Increased PDE5 activity and decreased Rho kinase and PKC activities in colonic muscle from caveolin-1-/- mice impair the peristaltic reflex and propulsion

scientific article published on 24 October 2013

Inflammation-induced "channelopathies" in the gastrointestinal smooth muscle.

scientific article published in January 2004

Interactive HIV-1 Tat and morphine-induced synaptodendritic injury is triggered through focal disruptions in Na⁺ influx, mitochondrial instability, and Ca²⁺ overload.

scientific article

Modulation of voltage-dependent Ca2+ channels in rabbit colonic smooth muscle cells by c-Src and focal adhesion kinase.

scientific article published on February 1998

Monochloramine directly modulates Ca(2+)-activated K(+) channels in rabbit colonic muscularis mucosae

scientific article

Morphine decreases enteric neuron excitability via inhibition of sodium channels.

scientific article

Morphine tolerance in the mouse ileum and colon

scientific article published on 05 August 2008

Nicotine suppresses hyperexcitability of colonic sensory neurons and visceral hypersensivity in mouse model of colonic inflammation.

scientific article published on 12 January 2012

Nitrotyrosylation of Ca2+ channels prevents c-Src kinase regulation of colonic smooth muscle contractility in experimental colitis

scientific article

Novel insights on the effect of nicotine in a murine colitis model.

scientific article

Opioid-induced hypernociception is associated with hyperexcitability and altered tetrodotoxin-resistant Na+ channel function of dorsal root ganglia

scientific article published on 21 December 2011

PKD2 functions as an epidermal growth factor-activated plasma membrane channel

scientific article published on September 2005

Prolonged sympathetic innervation of sensory neurons in rat thoracolumbar dorsal root ganglia during chronic colitis

scientific article published on 24 May 2011

Protein and gene expression of Ca2+ channel isoforms in murine colon: effect of inflammation.

scientific article published in December 2004

Sepiapterin Ameliorates Chemically Induced Murine Colitis and Azoxymethane-Induced Colon Cancer ⬇️

scientific article published on 02 August 2013

Signal-transduction pathways that regulate smooth muscle function. II. Receptor-ion channel coupling mechanisms in gastrointestinal smooth muscle.

scientific article

Site and mechanism of morphine tolerance in the gastrointestinal tract

scientific article published on October 2014

Specific localization of β-Arrestin2 in myenteric plexus of mouse gastrointestinal tract

scientific article

The Role of β-Arrestin2 in the Mechanism of Morphine Tolerance in the Mouse and Guinea Pig Gastrointestinal Tract ⬇️

scientific article published on November 30, 2011

The effect of tyrosine nitration of L-type Ca2+ channels on excitation-transcription coupling in colonic inflammation.

scientific article

The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a-go-go related gene currents in Xenopus oocytes

scientific article published in January 2006

Tolerance to Morphine-Induced Inhibition of TTX-R Sodium Channels in Dorsal Root Ganglia Neurons Is Modulated by Gut-Derived Mediators

scientific article published on 01 April 2018

Up-regulation of brain-derived neurotrophic factor in primary afferent pathway regulates colon-to-bladder cross-sensitization in rat

scientific article published on 15 February 2012

{alpha}7-nAChR-mediated suppression of hyperexcitability of colonic dorsal root ganglia neurons in experimental colitis

scientific article

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