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List of works by Klaus Heese

3D Structure, Dimerization Modeling, and Lead Discovery by Ligand-protein Interaction Analysis of p60 Transcription Regulator Protein (p60TRP).

scientific article

A Novel Divergent Gene Transcription Paradigm-the Decisive, Brain-Specific, Neural |-Srgap2-Fam72a-| Master Gene Paradigm

scientific article published on 26 January 2019

A cancer tissue-specific FAM72 expression profile defines a novel glioblastoma multiform (GBM) gene-mutation signature

article

A novel specialized single-linkage clustering algorithm for taxonomically ordered data

scientific article

ABC transporters, neural stem cells and neurogenesis--a different perspective

scientific article published on November 2006

Accurate high throughput alignment via line sweep-based seed processing

scientific article published on 26 April 2019

Ageing, dementia and society - an epistemological perspective

scientific article published on 20 March 2015

All-or-(N)One - an epistemological characterization of the human tumorigenic neuronal paralogous FAM72 gene loci

scientific article published on 20 July 2015

Alzheimer's disease--an interactive perspective

scientific article

Brain plasticity, cognitive functions and neural stem cells: a pivotal role for the brain-specific neural master gene |-SRGAP2-FAM72-|.

scientific article published on 28 August 2017

Brain site-specific proteome changes in aging-related dementia

scientific article published on 06 September 2013

Brain-derived neurotrophic factor (BDNF) has proliferative effects on neural stem cells through the truncated TRK-B receptor, MAP kinase, AKT, and STAT-3 signaling pathways

scientific article published in February 2009

Brain-site-specific proteome changes induced by neuronal P60TRP expression

scientific article

CRISPR-mediated upregulation of DR5 and downregulation of cFLIP synergistically sensitize HeLa cells to TRAIL-mediated apoptosis

scientific article published on 09 March 2019

Cardiovascular dementia - a different perspective

scientific article published on 26 March 2010

Characterization of a Solvent-Tolerant Manganese Peroxidase (MnP) fromGanoderma Lucidumand Its Application in Fruit Juice Clarification

Characterization of a novel endoglucanase from Ganoderma lucidum

scientific article published on 20 April 2015

Characterization of a solvent, surfactant and temperature-tolerant laccase from Pleurotus sp. MAK-II and its dye decolorizing property.

scientific article published on 28 August 2015

Characterization of lignocellulolytic enzymes from white-rot fungi

scientific article published on 09 December 2014

Characterization of optimized production, purification and application of laccase from Ganoderma lucidum

article

Characterization of the novel protein P9TLDR (temporal lobe down-regulated) with a brain-site-specific gene expression modality in Alzheimer's disease brain

scientific article

Characterizing CGI-94 (comparative gene identification-94) which is down-regulated in the hippocampus of early stage Alzheimer's disease brain

scientific article

Characterizing the neurite outgrowth inhibitory effect of Mani

scientific article

Characterizing the new transcription regulator protein p60TRP

scientific article

Characterizing the novel protein p33MONOX

scientific journal article

Characterizing the signaling pathway of rat p18 amyloid beta (A??) responsive protein (p18A??rP)

Cognitive Functions: Human vs. Animal - 4:1 Advantage |-FAM72-SRGAP2-|.

scientific article

Comparative gene identification-94--a pivotal regulator of apoptosis

scientific article

Death effector domain DEDa, a self-cleaved product of caspase-8/Mch5, translocates to the nucleus by binding to ERK1/2 and upregulates procaspase-8 expression via a p53-dependent mechanism

scientific article

Decreased trkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease

scientific article published on January 1998

Effects of high glucose on cytokine-induced nerve growth factor (NGF) expression in rat renal mesangial cells

scientific article

Establishing a human adrenocortical carcinoma (ACC)-specific gene mutation signature

scientific article published on 09 November 2018

Establishing an in vivo p48ZnF bioluminescence mouse brain imaging model

scientific article published on March 5, 2013

Expression of interleukin-6 and its receptor in the sciatic nerve and cultured Schwann cells: relation to 18-kD fibroblast growth factor-2

scientific article published on 01 December 2000

Functional repertoire of interleukin-6 in the central nervous system - a review

scientific article published on 9 October 2017

G proteins, p60TRP, and neurodegenerative diseases

scientific article published on 24 January 2013

GABAB receptor antagonists elevate both mRNA and protein levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) but not neurotrophin-3 (NT-3) in brain and spinal cord of rats

scientific article published on 01 January 2000

Gastrodia elata modulates amyloid precursor protein cleavage and cognitive functions in mice

scientific article published in January 2011

Glutamate E15 and E171 are Hotspots in p60TRP-Related Cancer

scientific article published on 6 February 2016

Identification and characterisation of the novel amyloid-beta peptide-induced protein p17

scientific journal article

Identification of a Novel Thermostable Alkaline Protease from <i>Bacillus megaterium</i>-TK1 for the Detergent and Leather Industry

scientific article published on 16 December 2020

Identification of a new synaptic vesicle protein 2B mRNA transcript which is up-regulated in neurons by amyloid beta peptide fragment (1-42).

scientific article

Identification of rTid-1, the rat homologue of the drosophila tumor suppressor l(2)tid gene

scientific journal article

Improvement of Saccharification and Delignification Efficiency of Trichoderma reesei Rut-C30 by Genetic Bioengineering

scientific article published on 23 January 2020

Increased CSF levels of nerve growth factor in patients with Alzheimer's disease

scientific article published on 01 May 2000

Increased cerebrospinal fluid levels of neurotrophin 3 (NT-3) in elderly patients with major depression

scientific article published in September 2000

Induction of rat l-phosphoserine phosphatase by amyloid-β (1–42) is inhibited by interleukin-11

scientific article published on 01 July 2000

Inflammatory Signals Induce Neurotrophin Expression in Human Microglial Cells

article published in 2002

Interleukin-6 (IL-6) and soluble forms of IL-6 receptors are not altered in cerebrospinal fluid of Alzheimer's disease patients

scientific article published in December 1997

Interleukin-6 and neural stem cells: more than gliogenesis

scientific article published on 29 October 2008

Interleukin-6-Mediated Induced Pluripotent Stem Cell (iPSC)-Derived Neural Differentiation

scientific article

Lead discovery and in silico 3D structure modeling of tumorigenic FAM72A (p17).

scientific article

Ligand-dependent activation of the chimeric tumor necrosis factor receptor-amyloid precursor protein (APP) reveals increased APP processing and suppressed neuronal differentiation

scientific article published on 29 September 2009

Livebearing or egg-laying mammals: 27 decisive nucleotides of FAM168.

scientific article

Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway

scientific article

MAGNITUDE OF THYMINE IN DIFFERENT FRAMES OF MESSENGER RNAs

Mechanism Study of Traditional Medicine Using Proteomics Alone or Integrated with Other Systems Biology Technologies.

scientific article published on 22 December 2015

Modulation of mRNA expression of the neurotrophins of the nerve growth factor family and their receptors in the septum and hippocampus of rats after transient postnatal thyroxine treatment. I. Expression of nerve growth factor, brain-derived neurotr

scientific article published in March 1998

Modulation of mRNA expression of the neurotrophins of the nerve-growth-factor family and their receptors in the septum and hippocampus of rats after transient postnatal thyroxine treatment. II. Effects on p75 and trk receptor expression

scientific article published in August 1999

NF-kappaB modulates lipopolysaccharide-induced microglial nerve growth factor expression

scientific article published in April 1998

Nerve growth factor (NGF) expression in rat microglia is induced by adenosine A2a-receptors

scientific article published on 01 August 1997

Nerve growth factor (NGF) induces mRNA expression of the new transcription factor protein p48ZnF.

scientific article published in April 2004

Nerve growth factor, neural stem cells and Alzheimer's disease

scientific article published on 4 July 2006

Neuronal p60TRP expression modulates cardiac capacity

scientific article published on 6 December 2011

Neurotrophin Signaling and Stem Cells-Implications for Neurodegenerative Diseases and Stem Cell Therapy

scientific article published on 5 November 2016

Neurotrophin-4 (ntf4) mediates neurogenesis in mouse embryonic neural stem cells through the inhibition of the signal transducer and activator of transcription-3 (stat3) and the modulation of the activity of protein kinase B.

scientific article published on 21 April 2010

Neurotrophins - More than Neurotrophic

article

New insights into the brain protein metabolism of Gastrodia elata-treated rats by quantitative proteomics

scientific article published on 3 March 2012

Oxygen distribution in proteins defines functional significance of the genome and proteome of the malaria parasite Plasmodium falciparum 3D7.

scientific article

P60TRP interferes with the GPCR/secretase pathway to mediate neuronal survival and synaptogenesis

scientific journal article

Phenotyping of an in vitro model of ischemic penumbra by iTRAQ-based shotgun quantitative proteomics

scientific article

Phenotyping of tianma-stimulated differentiated rat neuronal b104 cells by quantitative proteomics

scientific article

Possible mechanisms of A beta(1-40)- or A beta(1-42)-induced cell death and their rescue factors

scientific article

Proteomic Atomics Reveals a Distinctive Uracil-5-Methyltransferase

scientific article published on 15 January 2020

Proteomics in Traditional Chinese Medicine with an Emphasis on Alzheimer's Disease

scientific article

Quantitative clinical proteomic study of autopsied human infarcted brain specimens to elucidate the deregulated pathways in ischemic stroke pathology

scientific article published on 2 September 2013

Quantitative neuroproteomics of an in vivo rodent model of focal cerebral ischemia/reperfusion injury reveals a temporal regulation of novel pathophysiological molecular markers

scientific article

Region-Specific Neurotrophin Imbalances in Alzheimer Disease

scientific article published on 01 June 2000

Role of interleukin-6 and soluble IL-6 receptor in region-specific induction of astrocytic differentiation and neurotrophin expression

scientific article published in May 1999

Secretome analysis of Ganoderma lucidum cultivated in sugarcane bagasse

scientific article published on 20 September 2012

The 3' untranslated region of the new rat synaptic vesicle protein 2B mRNA transcript inhibits translational efficiency

scientific article

The Bad guy cooperates with good cop p53: Bad is transcriptionally up-regulated by p53 and forms a Bad/p53 complex at the mitochondria to induce apoptosis

scientific article

The Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's Disease

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The novel protein MANI modulates neurogenesis and neurite-cone growth

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The protein p17 signaling pathways in cancer

scientific article published on July 31, 2013

The splicing regulatory protein p18SRP is down-regulated in Alzheimer's disease brain

scientific article

Thymine distribution in genes provides novel insight into the functional significance of the proteome of the malaria parasite Plasmodium falciparum 3D7.

scientific article published on 15 October 2013

Tianma modulates blood vessel tonicity

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Tianma modulates proteins with various neuro-regenerative modalities in differentiated human neuronal SH-SY5Y cells

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