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List of works by Hannu Kankaanranta

12-year adherence to inhaled corticosteroids in adult-onset asthma

scientific article published on 01 January 2020

Add-on therapy options in asthma not adequately controlled by inhaled corticosteroids: a comprehensive review

scientific article

Adipokine resistin predicts anti-inflammatory effect of glucocorticoids in asthma

scientific article

Adipokines NUCB2/nesfatin-1 and visfatin as novel inflammatory factors in chronic obstructive pulmonary disease

scientific article

Age- and gender-specific incidence of new asthma diagnosis from childhood to late adulthood

scientific article published on 08 June 2019

Age-specific incidence of allergic and non-allergic asthma

scientific article published on 10 January 2020

Anti-inflammatory activity of extracts from leaves of Phyllanthus emblica.

scientific article

Antieosinophilic activity of orazipone

scientific article published on 15 March 2006

Antieosinophilic activity of simendans

scientific article published on 09 July 2007

Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1.

scientific article published on August 2013

Aurothiomalate inhibits COX-2 expression in chondrocytes and in human cartilage possibly through its effects on COX-2 mRNA stability

scientific article published on 29 March 2008

Bacterial DNA delays human eosinophil apoptosis.

scientific article

Beclomethasone, budesonide and fluticasone propionate inhibit human neutrophil apoptosis

scientific article published in November 2001

Beta2-agonists potentiate corticosteroid-induced neutrophil survival

scientific article published in June 2008

Bi-directional effects of the elevation of intracellular calcium on the expression of inducible nitric oxide synthase in J774 macrophages exposed to low and to high concentrations of endotoxin

scientific article

Bringing asthma care into the twenty-first century

scientific article published on 05 June 2020

Bronchial diffusing capacity of nitric oxide is increased in patients with allergic rhinitis.

scientific article

Bronchial nitric oxide is related to symptom relief during fluticasone treatment in COPD.

scientific article

Concurrent decline of several antioxidants and markers of oxidative stress during combination chemotherapy for small cell lung cancer.

scientific article published on 13 May 2009

Cost effectiveness of adding budesonide/formoterol to tiotropium in COPD in four Nordic countries ⬇️

scientific article published on July 13, 2013

Cost-effectiveness analysis of budesonide/formoterol maintenance and reliever therapy versus fixed combination treatments for asthma in Finland*

scientific article published on 01 December 2008

Cumulative effect of smoking on disease burden and multimorbidity in adult-onset asthma

scientific article published on 05 September 2019

Daily physical activity and lung function decline in adult-onset asthma: a 12-year follow-up study

scientific article published on 24 October 2018

Decreased COPD prevalence in Sweden after decades of decrease in smoking

scientific article published on 28 October 2020

Delayed eosinophil apoptosis in asthma

scientific article published on 01 July 2000

Dexamethasone inhibits inducible nitric-oxide synthase expression and nitric oxide production by destabilizing mRNA in lipopolysaccharide-treated macrophages

scientific article published in September 2002

Differences in diagnostic patterns of obstructive airway disease between areas and sex in Sweden and Finland - The Nordic EpiLung Study

scientific article published on 30 May 2020

Divergent effect of mometasone on human eosinophil and neutrophil apoptosis

scientific article published in August 2002

Down-regulation of tristetraprolin expression results in enhanced IL-12 and MIP-2 production and reduced MIP-3alpha synthesis in activated macrophages.

scientific article published on January 2006

Dyspnea has an association with lifestyle: differences between Swedish and Finnish speaking persons in Western Finland

scientific article published on 10 December 2020

Econazole, miconazole and SK & F 96365 inhibit depolarization-induced and receptor-operated contraction of guinea-pig isolated trachea in vitro

scientific article published in July 1997

Effects of K(+) channel inhibitors on relaxation induced by flufenamic and tolfenamic acids in guinea-pig trachea

scientific article published on 01 October 1999

Effects of levo- and dextrosimendan on NF-kappaB-mediated transcription, iNOS expression and NO production in response to inflammatory stimuli.

scientific article

Effects of nimesulide, acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo.

scientific article

Effects of nitric oxide donors GEA 3162 and SIN-1 on ethanol-induced gastric ulceration in rats

scientific article published on 01 July 1999

Enhancement of human eosinophil apoptosis by fluticasone propionate, budesonide, and beclomethasone

scientific article published on 01 October 2000

Factor analysis identifies three separate symptom clusters in idiopathic pulmonary fibrosis

scientific article published on 05 October 2020

First-generation antihistamines diphenhydramine and chlorpheniramine reverse cytokine-afforded eosinophil survival by enhancing apoptosis

scientific article published in January 2007

Gremlin localization and expression levels partially differentiate idiopathic interstitial pneumonia severity and subtype

scientific article published in March 2008

Histamine reverses IL-5-afforded human eosinophil survival by inducing apoptosis: pharmacological evidence for a novel mechanism of action of histamine

scientific article published on 28 March 2007

Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils.

scientific article

Hydrogen peroxide reverses IL-5 afforded eosinophil survival and promotes constitutive human eosinophil apoptosis

scientific article published in January 2002

Increased alveolar nitric oxide concentration and high levels of leukotriene B(4) and 8-isoprostane in exhaled breath condensate in patients with asbestosis

scientific article published on 24 January 2007

Increased alveolar nitric oxide concentration in asthmatic patients with nocturnal symptoms

scientific article published in October 2002

Induction of nitric oxide synthesis by probiotic Lactobacillus rhamnosus GG in J774 macrophages and human T84 intestinal epithelial cells

scientific article

Inhaled fluticasone decreases bronchial but not alveolar nitric oxide output in asthma

scientific article published in October 2001

Inhibition by nitric oxide-releasing compounds of E-selectin expression in and neutrophil adhesion to human endothelial cells

scientific article published on 01 April 2000

Inhibition by nitric oxide-releasing compounds of prostacyclin production in human endothelial cells

scientific article published on September 1998

Inhibition of classical PKC isoenzymes downregulates STAT1 activation and iNOS expression in LPS-treated murine J774 macrophages.

scientific article published on April 2006

Inhibition of human lymphocyte proliferation by nitric oxide-releasing oxatriazole derivatives

scientific article published on 01 October 1997

Inhibition of iNOS expression and NO production by anti-inflammatory steroids. Reversal by histone deacetylase inhibitors.

scientific article

Inhibition of p38 mitogen-activated protein kinase enhances c-Jun N-terminal kinase activity: implication in inducible nitric oxide synthase expression

scientific article

Inhibition of protein kinase C beta II downregulates tristetraprolin expression in activated macrophages

scientific article published in May 2008

Inhibitors of mitogen-activated protein kinases downregulate COX-2 expression in human chondrocytes

scientific article

Interactions between synthesis of platelet-activating factor and leukotriene B4 in isolated human polymorphonuclear leukocytes

scientific article published on 01 December 1993

JNK inhibitor SP600125 reduces COX-2 expression by attenuating mRNA in activated murine J774 macrophages.

scientific article published on 9 February 2006

Janus kinase 3 inhibitor WHI-P154 in macrophages activated by bacterial endotoxin: differential effects on the expression of iNOS, COX-2 and TNF-alpha.

scientific article published on 20 November 2007

Ketotifen induces primary necrosis of human eosinophils

scientific article published in August 2005

Local and systemic oxidant/antioxidant status before and during lung cancer radiotherapy

scientific article published on July 2009

Multimorbidity in Finnish and Swedish speaking Finns; association with daily habits and socioeconomic status – Nordic EpiLung cross-sectional study

scientific article published in 2021

NORDSTAR: paving the way for a new era in asthma research

scientific article published on 03 April 2020

Nitric oxide induces apoptosis in GM-CSF-treated eosinophils via caspase-6-dependent lamin and DNA fragmentation.

scientific article published on 7 April 2010

Nitric oxide production and signaling in inflammation.

scientific article

Nitric oxide-induced eosinophil apoptosis is dependent on mitochondrial permeability transition (mPT), JNK and oxidative stress: apoptosis is preceded but not mediated by early mPT-dependent JNK activation.

scientific article published on 24 August 2012

Nitric oxide-releasing compounds inhibit neutrophil adhesion to endothelial cells

scientific article published on 01 October 1999

Occupational exposures and asthma-COPD overlap in a clinical cohort of adult-onset asthma

scientific article published on 21 October 2019

Orazipone inhibits activation of inflammatory transcription factors nuclear factor-kappa B and signal transducer and activator of transcription 1 and decreases inducible nitric-oxide synthase expression and nitric oxide production in response to inf

scientific article published on 26 November 2007

P38 mitogen-activated protein kinase inhibitor SB203580 has a bi-directional effect on iNOS expression and NO production

scientific article published on November 2002

PPARalpha agonists inhibit nitric oxide production by enhancing iNOS degradation in LPS-treated macrophages.

scientific article

Parallel gradients in FENO and in the prevalences of asthma and atopy in adult general populations of Sweden, Finland and Estonia - A Nordic EpiLung study

scientific article published on 17 September 2020

Peripheral blood neutrophil leukotriene B4 release and migration in rheumatoid arthritis

scientific article published in October 1996

Peripheral inflammation in patients with asthmatic symptoms but normal lung function

scientific article published in September 2005

Pharmacological control of human polymorphonuclear leukocyte degranulation by fenamates and inhibitors of receptor-mediated calcium entry and protein kinase C

scientific article published on 01 July 1995

Phosphodiesterase 4 inhibitors delay human eosinophil and neutrophil apoptosis in the absence and presence of salbutamol

scientific article

Planned primary health care asthma contacts during 12-year follow-up after Finnish National Asthma Programme: focus on spirometry

scientific article published on 20 March 2020

Pulmonary inflammation in asbestos-exposed subjects with borderline parenchymal changes on HRCT.

scientific article published on 16 February 2010

Radical releasing properties of nitric oxide donors GEA 3162, SIN-1 and S-nitroso-N-acetylpenicillamine ⬇️

scientific article published on April 3, 1998

Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5.

scientific article published in July 2003

Salbutamol delays human eosinophil apoptosis via a cAMP-dependent mechanism

scientific article

Salbutamol increases tristetraprolin expression in macrophages

scientific article published on 5 October 2007

Suppression of T-cell activation by Lactobacillus rhamnosus GG-degraded bovine casein

scientific article published in February 2001

The glucocorticoid RU24858 does not distinguish between transrepression and transactivation in primary human eosinophils.

scientific article

c-Jun N-terminal kinase mediates constitutive human eosinophil apoptosis

scientific article published on 11 July 2006

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