List of works - Claudia Gaspar

A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis

scientific article published on 3 July 2009

APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression

scientific article published on 16 August 2006

APC dosage effects in tumorigenesis and stem cell differentiation

scientific article published in January 2004

Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling

scientific article published on 11 November 2002

Autosomal-dominant locus for Restless Legs Syndrome in French-Canadians on chromosome 16p12.1.

scientific article

BAT-26 identifies sporadic colorectal cancers with mutator phenotype: a correlative study with clinico-pathological features and mutations in mismatch repair genes.

scientific article published in July 1999

Cancer stemness in Wnt-driven mammary tumorigenesis

scientific article published on 16 August 2013

Colonic cancer in a 34-yr-old woman: should it prompt microsatellite instability studies and mismatch repair gene testing?

article

Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo

scientific journal article

Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis

scientific article

Detection of mutations in mismatch repair genes in Portuguese families with hereditary non-polyposis colorectal cancer (HNPCC) by a multi-method approach

article

Expanded ATXN3 frameshifting events are toxic in Drosophila and mammalian neuron models.

scientific article published on 14 February 2012

Family study of restless legs syndrome in Quebec, Canada: clinical characterization of 671 familial cases

scientific article

Genetic association studies of neurotensin gene and restless legs syndrome in French Canadians

scientific article

Genome-wide TDT analysis in French-Canadian families with Tourette syndrome

scientific article published in January 2010

Molecular genetic studies of DMT1 on 12q in French-Canadian restless legs syndrome patients and families

scientific article

Morphological changes in tumour type after radiotherapy are accompanied by changes in gene expression profile but not in clinical behaviour

article

Mutations in the APC tumour suppressor gene cause chromosomal instability

scientific article published in April 2001

Neural commitment of human pluripotent stem cells under defined conditions recapitulates neural development and generates patient-specific neural cells.

scientific article

Radiation induces different changes in expression profiles of normal rectal tissue compared with rectal carcinoma.

scientific article published on 16 December 2004

Restless legs syndrome-associated MEIS1 risk variant influences iron homeostasis

scientific article published on 27 June 2011

Smad4 haploinsufficiency: a matter of dosage

scientific article published on 3 November 2008

Transgenic expression of an expanded (GCG)13 repeat PABPN1 leads to weakness and coordination defects in mice

scientific article (publication date: April 2005)

Transit defect of potassium-chloride Co-transporter 3 is a major pathogenic mechanism in hereditary motor and sensory neuropathy with agenesis of the corpus callosum

scientific article published on 31 May 2011

Two Notch ligands, Dll1 and Jag1, are differently restricted in their range of action to control neurogenesis in the mammalian spinal cord.

scientific article

Validation and simplification of Bethesda guidelines for identifying apparently sporadic forms of colorectal carcinoma with microsatellite instability

scientific article published on 01 February 1999

Wnt signaling inhibits osteogenic differentiation of human mesenchymal stem cells

scientific article published on May 2004

Wnt signaling regulates the lineage differentiation potential of mouse embryonic stem cells through Tcf3 down-regulation

scientific article

cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo

scholarly article

List of works by Claudia Gaspar

A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis

APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression

APC dosage effects in tumorigenesis and stem cell differentiation

Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling

Autosomal-dominant locus for Restless Legs Syndrome in French-Canadians on chromosome 16p12.1.

BAT-26 identifies sporadic colorectal cancers with mutator phenotype: a correlative study with clinico-pathological features and mutations in mismatch repair genes.

Cancer stemness in Wnt-driven mammary tumorigenesis

Colonic cancer in a 34-yr-old woman: should it prompt microsatellite instability studies and mismatch repair gene testing?

Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo

Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis

Detection of mutations in mismatch repair genes in Portuguese families with hereditary non-polyposis colorectal cancer (HNPCC) by a multi-method approach

Expanded ATXN3 frameshifting events are toxic in Drosophila and mammalian neuron models.

Family study of restless legs syndrome in Quebec, Canada: clinical characterization of 671 familial cases

Genetic association studies of neurotensin gene and restless legs syndrome in French Canadians

Genome-wide TDT analysis in French-Canadian families with Tourette syndrome

Molecular genetic studies of DMT1 on 12q in French-Canadian restless legs syndrome patients and families

Morphological changes in tumour type after radiotherapy are accompanied by changes in gene expression profile but not in clinical behaviour

Mutations in the APC tumour suppressor gene cause chromosomal instability

Neural commitment of human pluripotent stem cells under defined conditions recapitulates neural development and generates patient-specific neural cells.

Radiation induces different changes in expression profiles of normal rectal tissue compared with rectal carcinoma.

Restless legs syndrome-associated MEIS1 risk variant influences iron homeostasis

Smad4 haploinsufficiency: a matter of dosage

Transgenic expression of an expanded (GCG)13 repeat PABPN1 leads to weakness and coordination defects in mice

Transit defect of potassium-chloride Co-transporter 3 is a major pathogenic mechanism in hereditary motor and sensory neuropathy with agenesis of the corpus callosum

Two Notch ligands, Dll1 and Jag1, are differently restricted in their range of action to control neurogenesis in the mammalian spinal cord.

Validation and simplification of Bethesda guidelines for identifying apparently sporadic forms of colorectal carcinoma with microsatellite instability

Wnt signaling inhibits osteogenic differentiation of human mesenchymal stem cells

Wnt signaling regulates the lineage differentiation potential of mouse embryonic stem cells through Tcf3 down-regulation

cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo