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List of works by Edward A Lemke

A general and efficient method for the site-specific dual-labeling of proteins for single molecule fluorescence resonance energy transfer

scientific article

A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures.

scholarly article

A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins

scientific article published on 6 January 2013

A new family of bioorthogonally applicable fluorogenic labels.

scientific article

Amino acids for Diels-Alder reactions in living cells.

scientific article

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.

scientific article published on 7 November 2017

Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines

scientific article

Click strategies for single-molecule protein fluorescence

scientific article published on 05 March 2012

Comment on “Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water”

scientific article published in Science

Conserved features of intermediates in amyloid assembly determine their benign or toxic states ⬇️

scientific article published on June 27, 2012

Continuous throughput and long-term observation of single-molecule FRET without immobilization

scientific article published on 19 January 2014

Control of protein phosphorylation with a genetically encoded photocaged amino acid

scientific article

Debugging Eukaryotic Genetic Code Expansion for Site-Specific Click-PAINT Super-Resolution Microscopy.

scientific article published on 2 November 2016

Designer membraneless organelles enable codon reassignment of selected mRNAs in eukaryotes

scientific article published on 01 March 2019

Dual film-like organelles enable spatial separation of orthogonal eukaryotic translation

scientific article published on 24 August 2021

Facilitated aggregation of FG nucleoporins under molecular crowding conditions

scientific article

Fourier ring correlation as a resolution criterion for super-resolution microscopy.

scientific article published on 16 May 2013

Genetic code expansion enabled site-specific dual-color protein labeling: superresolution microscopy and beyond

scientific article (publication date: October 2015)

Genetic code expansion for multiprotein complex engineering.

scientific article

Genetic encoding of a bicyclo[6.1.0]nonyne-charged amino acid enables fast cellular protein imaging by metal-free ligation.

scientific article published on 3 September 2012

Genetic incorporation of a small, environmentally sensitive, fluorescent probe into proteins in Saccharomyces cerevisiae.

scientific article

Genetically encoded click chemistry for single-molecule FRET of proteins

scientific article published in January 2013

Genetically encoded copper-free click chemistry

scientific article

Highly Stable trans-Cyclooctene Amino Acids for Live-Cell Labeling

scientific article published on 15 July 2015

Hydrophilic trans-Cyclooctenylated Noncanonical Amino Acids for Fast Intracellular Protein Labeling

scientific article published on 25 May 2016

Immune complexes of auto-antibodies against A beta 1-42 peptides patrol cerebrospinal fluid of non-Alzheimer's patients

scientific article published on 6 February 2007

In situ structural analysis of the human nuclear pore complex

scientific article

Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence.

scholarly article

Intramolecular three-colour single pair FRET of intrinsically disordered proteins with increased dynamic range ⬇️

scientific article published on October 1, 2012

Kirkwood-Buff Approach Rescues Overcollapse of a Disordered Protein in Canonical Protein Force Fields.

scientific article

Labeling of virus components for advanced, quantitative imaging analyses.

scientific article published on 14 March 2016

Labeling proteins on live mammalian cells using click chemistry

scientific article

Large-Scale Conformational Dynamics Control H5N1 Influenza Polymerase PB2 Binding to Importin α.

scientific article

Mapping multivalency and differential affinities within large intrinsically disordered protein complexes with segmental motion analysis

scientific article published on 04 June 2014

Mechanism-Dependent Modulation of Ultrafast Interfacial Water Dynamics in Intrinsically Disordered Protein Complexes

scientific article published on 28 February 2019

Microfluidic device for single-molecule experiments with enhanced photostability

scientific article published on September 2009

Minimal tags for rapid dual-color live-cell labeling and super-resolution microscopy

scientific article published on 28 January 2014

Molecular anatomy of a trafficking organelle

scientific article

Molecular determinants of large cargo transport into the nucleus

scientific article published on 21 July 2020

Nanoscale devices for linkerless long-term single-molecule observation

scientific article

New Red-Emitting Tetrazine-Phenoxazine Fluorogenic Labels for Live-Cell Intracellular Bioorthogonal Labeling Schemes.

scientific article published on 24 May 2016

New generation of bioorthogonally applicable fluorogenic dyes with visible excitations and large Stokes shifts

scientific article published on 23 June 2014

Origin of Orthogonality of Strain-Promoted Click Reactions

scientific article published on 14 July 2015

Plasticity of an ultrafast interaction between nucleoporins and nuclear transport receptors

scientific article published on 7 October 2015

Precision Control of Cellular Pathways with Light ⬇️

scientific article published on September 3, 2010

Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study

scientific article published on 31 August 2018

Principles for designing fluorescent sensors and reporters

scientific article published on 18 July 2011

Raising the ribosomal repertoire

scientific article published on 29 May 2020

Single molecule study of the intrinsically disordered FG-repeat nucleoporin 153.

scientific article published on October 2011

Single synaptic vesicle tracking in individual hippocampal boutons at rest and during synaptic activity.

scientific article published in November 2005

Single-molecule FRET and crosslinking studies in structural biology enabled by noncanonical amino acids.

scientific article

Single-molecule biophysics: at the interface of biology, physics and chemistry

scientific article

Site-Specific Labeling of Proteins for Single-Molecule FRET Measurements Using Genetically Encoded Ketone Functionalities ⬇️

scientific article published on January 1, 2011

Super-resolution Microscopy of Clickable Amino Acids Reveals the Effects of Fluorescent Protein Tagging on Protein Assemblies

scientific article published on 25 October 2015

The CD27L and CTP1L Endolysins Targeting Clostridia Contain a Built-in Trigger and Release Factor

scientific article

The Multiple Faces of Disordered Nucleoporins

scientific article

The exploding genetic code

scientific article published on 30 July 2014

The liquid state of FG-nucleoporins mimics permeability barrier properties of nuclear pore complexes

scientific article published on 01 January 2020

Unnatural amino acid mutagenesis reveals dimerization as a negative regulatory mechanism of VHR's phosphatase activity.

scientific article

Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing.

scientific article

What precision-protein-tuning and nano-resolved single molecule sciences can do for each other.

scientific article

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