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List of works by Mark A Ainsworth

A role for thiopurine metabolites in the synergism between thiopurines and infliximab in inflammatory bowel disease

scientific article published on 14 November 2017

Absence of Relationship Between Crohn's Disease Activity Index or C-Reactive Protein and Infliximab Exposure Calls for Objective Crohn's Disease Activity Measures for the Evaluation of Treatment Effects at Treatment Failure

scientific article published in April 2019

Absence of relationship between CDAI or CRP and infliximab exposure calls for objective Crohn's disease activity measures for the evaluation of treatment effects at treatment failure

scientific article published on 26 December 2018

Acid-base transport in isolated rabbit duodenal villus and crypt cells

scientific article

Acid-stimulated duodenal bicarbonate secretion involves a CFTR-mediated transport pathway in mice

scientific article published in August 1997

Acid/base transporters in human duodenal enterocytes

scientific article published in October 1998

Acute and delayed hypersensitivity reactions to infliximab and adalimumab in a patient with Crohn's disease

scientific article published on 31 August 2011

Antibodies against infliximab are associated with de novo development of antibodies to adalimumab and therapeutic failure in infliximab-to-adalimumab switchers with IBD

scientific article published on 01 October 2014

Authors' response: Importance of defining loss of response before therapeutic drug monitoring

scientific article

Biological treatment of Crohn's disease

scientific article

Biosimilars for Management of Crohn Disease

scientific article published on 11 December 2018

CFTR mediates cAMP- and Ca2+-activated duodenal epithelial HCO3- secretion

scientific article published in April 1997

Challenges and opportunities for IBD drug development: from early stage to regulatory approval

scientific article published on 16 March 2020

Changes in serum trough levels of infliximab during treatment intensification but not in anti-infliximab antibody detection are associated with clinical outcomes after therapeutic failure in Crohn's disease

scientific article published on 09 January 2015

Cigarette smoking inhibits acid-stimulated duodenal mucosal bicarbonate secretion

scientific article published in November 1993

Circulating Cytokines and Cytokine Receptors in Infliximab Treatment Failure Due to TNF-α Independent Crohn Disease

scientific article published on April 2016

Clinical implications of measuring drug and anti-drug antibodies by different assays when optimizing infliximab treatment failure in Crohn's disease: post hoc analysis of a randomized controlled trial

scientific article published on 6 May 2014

Clinical implications of variations in anti-infliximab antibody levels in patients with inflammatory bowel disease

scientific article published on 16 February 2012

Comment on 'Predicting the response to infliximab from trough serum levels'

scientific article published on 01 September 2010

Comparison of techniques for monitoring infliximab and antibodies against infliximab in Crohn's disease

scientific article published in August 2013

Cut-off levels and diagnostic accuracy of infliximab trough levels and anti-infliximab antibodies in Crohn's disease

scientific article published on 18 November 2010

Cyclic adenosine-3',5'-monophosphate production is greater in rabbit duodenal crypt than in villus cells

scientific article published in March 1996

Defence mechanisms of the gastroduodenal mucosa. The significance of epithelial and subepithelial factors for the development of acute and chronic ulceration

scientific article published in September 1990

Defense mechanisms of the gastroduodenal mucosa: the role of mucus and bicarbonate in the development of peptic ulcer

scientific article published in October 1989

Discontinuation of infliximab therapy in patients with Crohn's disease in sustained complete remission (the STOP IT study): protocol for a double-blind, randomised, placebo-controlled, multicentre trial

scientific article

Duodenal disappearance rate of acid during inhibition of mucosal bicarbonate secretion

scientific article published on 01 January 1990

Duodenal mucosal bicarbonate secretion in pigs is accompanied by compensatory changes in pancreatic and biliary HCO3- secretion

scientific article published on 01 October 1994

Effect of stimulation of mucosal HCO3- secretion on acid-induced injury to porcine duodenal mucosa

scientific article published on 01 December 1993

Effect of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide on pancreatic, hepatic and duodenal mucosal bicarbonate secretion in the pig.

scientific article published in January 2003

Effects of oleic acid and oleyl alcohol on cholecystokinin and secretin in plasma and pancreatobiliary secretion

scientific article published on 01 June 1989

Exogenous prostaglandins, alkaline secretion, and protection of duodenal mucosa

scientific article published on 01 July 1990

Genetic polymorphisms of tumour necrosis factor receptor superfamily 1b and fas ligand are associated with clinical efficacy and/or acute severe infusion reactions to infliximab in Crohn's disease

scientific article published on 05 August 2012

Higher proximal duodenal mucosal bicarbonate secretion is independent of Brunner's glands in rats and rabbits

scientific article published on October 1995

Implications of Infliximab Treatment Failure and Influence of Personalized Treatment on Patient-reported Health-related Quality of Life and Productivity Outcomes in Crohn's Disease.

scientific article published on 5 August 2015

Individual medicine in inflammatory bowel disease: monitoring bioavailability, pharmacokinetics and immunogenicity of anti-tumour necrosis factor-alpha antibodies

scientific article published on January 2009

Individualised therapy is more cost-effective than dose intensification in patients with Crohn's disease who lose response to anti-TNF treatment: a randomised, controlled trial

scientific article published on 22 July 2013

Individualized Therapy Is a Long-Term Cost-Effective Method Compared to Dose Intensification in Crohn's Disease Patients Failing Infliximab.

scientific article published on 12 February 2015

Inflammatory Bowel Disease with Primary Sclerosing Cholangitis: a Danish Population-based Cohort Study 1977-2011.

scientific article published on 10 August 2017

Infliximab clearance decreases in the second and third trimesters of pregnancy in inflammatory bowel disease

scientific article published on 20 October 2020

Interactions Between Thiopurine Metabolites, Adalimumab, and Antibodies Against Adalimumab in Previously Infliximab-Treated Patients with Inflammatory Bowel Disease

scientific article published on 21 March 2018

Intestinal permeability of 51Cr-labelled ethylenediaminetetraacetic acid in patients with Crohn's disease and their healthy relatives

scientific article published on October 1989

Long-term effects and colectomy rates in ulcerative colitis patients treated with infliximab: a Danish single center experience

scientific article published on 11 August 2010

Magnitude of Increased Infliximab Clearance Imposed by Anti-infliximab Antibodies in Crohn's Disease Is Determined by Their Concentration

scientific article published on 13 October 2016

Management of Iron-Deficiency Anemia in Inflammatory Bowel Disease: A Systematic Review

scientific article published on June 2015

Metabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease

scientific article published on 16 October 2017

Methotrexate for inflammatory bowel disease: time for reconsideration

scientific article published on 21 March 2019

Molecular and functional evidence for electrogenic and electroneutral Na(+)-HCO(3)(-) cotransporters in murine duodenum.

scientific article

Monitoring immunogenicity of protein-based TNF antagonists

scientific article published on 14 May 2015

Morphine inhibits secretion of bicarbonate from the human duodenal mucosa. Possible role of endogenous opioids in the regulation of human duodenal mucosal bicarbonate secretion

scientific article published on 01 October 1990

Optimizing Treatment with TNF Inhibitors in Inflammatory Bowel Disease by Monitoring Drug Levels and Antidrug Antibodies.

scientific article published on 29 April 2016

Outcome after discontinuation of infliximab in patients with inflammatory bowel disease in clinical remission: an observational Danish single center study

scientific article published in March 2012

Outcome of continued infliximab therapy in Crohn's disease patients with response but without remission after one year of infliximab - a retrospective cohort study.

scientific article published on 10 July 2018

Outcomes After Primary Infliximab Treatment Failure in Inflammatory Bowel Disease

scientific article published in July 2017

Pancreatic, hepatic, and duodenal mucosal bicarbonate secretion during infusion of secretin and cholecystokinin. Evidence of the importance of hepatic bicarbonate in the neutralization of acid in the duodenum of anaesthetized pigs

scientific article published on 01 October 1991

Physicians' participation in clinical drug trials

scientific article published in April 2003

Progression-free survival (PFS) in oncology: caveat emptor!

scientific article published on 22 January 2019

Rectal dialysate and fecal concentrations of neutrophil gelatinase-associated lipocalin, interleukin-8, and tumor necrosis factor-alpha in ulcerative colitis.

scientific article published on October 1999

Relative importance of pancreatic, hepatic, and mucosal bicarbonate in duodenal neutralization of acid in anaesthetized pigs.

scientific article

Reporter gene assay for the quantification of the activity and neutralizing antibody response to TNFα antagonists

scientific article published on 03 September 2011

Severe infusion reactions to infliximab: aetiology, immunogenicity and risk factors in patients with inflammatory bowel disease

scientific article published on 3 May 2011

Systematic Information to Health-Care Professionals about Vaccination Guidelines Improves Adherence in Patients With Inflammatory Bowel Disease in Anti-TNFα Therapy

scientific article

Systematic review: coxibs, non-steroidal anti-inflammatory drugs or no cyclooxygenase inhibitors in gastroenterological high-risk patients?

scientific article

Tegaserod in treatment of women with irritable bowel syndrome

scientific article

Telephone reminders reduced the non-attendance rate in a gastroenterology outpatient clinic

scientific article

The cystic fibrosis transmembrane conductance regulator is not a base transporter in isolated duodenal epithelial cells

scientific article

The effect of gastrin-releasing peptide on porcine pancreaticobiliary bicarbonate secretion is mediated by secretin

scientific article published on 01 March 1994

Therapeutic infliximab drug level in a child born to a woman with ulcerative colitis treated until gestation week 31

scientific article published on 28 October 2011

Therapeutic thresholds and mechanisms for primary non-response to infliximab in inflammatory bowel disease

scientific article published on 06 July 2020

Time Course and Clinical Implications of Development of Antibodies Against Adalimumab in Patients With Inflammatory Bowel Disease

scientific article published in July 2016

Transjugular intrahepatic portosystemic stent-shunts or paracentesis in the treatment of cirrhotic patients with refractory ascites

scientific article published in August 2005

Treatment to target in patients with inflammatory bowel disease. What is the evidence?

scientific article published on 05 June 2020

Tumor Necrosis Factor Inhibitors for Inflammatory Bowel Disease ⬇️

scientific article published on August 22, 2013

Tumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease

scientific article published on 19 November 2007

Which biological agents are most appropriate for ulcerative colitis?

scientific article published on 01 May 2014

Will novel oral formulations change the management of inflammatory bowel disease?

scientific article published on 11 March 2016

[Anti-TNF-alpha antibody treatment of patients with active ulcerative colitis]

scientific article published on 01 February 2007

[Approval of new medicinal products - administrative procedures] ⬇️

scientific article published on 01 May 2019

[Approval of new medicinal products - documentation requirements] ⬇️

scientific article published on 01 May 2019

[Eosinophilic gastroenteritis with liver involvement and ascites]

scientific article published on 01 June 1988

[In Process Citation] ⬇️

[Monitoring of bioavailability, pharmacokinetics and immunogenicity of tumour necrosis factor-alpha inhibitors]

scientific article published on 01 January 2010

[New drugs and European procedures of approval. The European Agency for the Evaluation of Medicinal Products' role]

scientific article published on 01 April 2003

[Pharmacogenetics--new therapeutic possibilities]

scientific article published on 01 May 2005

[Summary of product characteristics--what is it and how is it used?]

scientific article published on 01 October 1999

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