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List of works by David H. Margulies

"Exon-shuffling" maps control of antibody- and T-cell-recognition sites to the NH2-terminal domain of the class II major histocompatibility polypeptide A beta.

scientific article published on May 1985

A "chimeric" C57l-derived Ly49 inhibitory receptor resembling the Ly49D activation receptor

scientific article published in April 2001

A Novel MHC-I Surface Targeted for Binding by the MCMV m06 Immunoevasin Revealed by Solution NMR.

scientific article

A T cell receptor transgenic model of severe, spontaneous organ-specific autoimmunity

scientific article published on 01 July 2001

A serine/threonine phosphorylation site in the ectodomain of a T cell receptor beta chain is required for activation by superantigen

scientific article published on February 2003

A simple method for polyethylene glycol-promoted hybridization of mouse myeloma cells

scientific article published on March 1977

A structural and molecular dynamics approach to understanding the peptide-receptive transition state of MHC-I molecules.

scientific article

A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis and alters thymocyte development

scientific article published on 01 November 1995

Activating CTL precursors to reveal CTL function without skewing the repertoire by in vitro expansion

scientific article published in December 2001

An allosteric mechanism controls antigen presentation by the H-2K(b) complex

scientific article

Antigen-processing and presentation pathways select antigenic HIV peptides in the fight against viral evolution.

scientific article

Availability of autoantigenic epitopes controls phenotype, severity, and penetrance in TCR Tg autoimmune gastritis

scientific article published on December 2008

Backbone and side chain resonance assignmentsof a TRAV14-3 mouse T cell receptor domain

scientific article published in March 2005

Binding of the natural killer cell inhibitory receptor Ly49A to its major histocompatibility complex class I ligand. Crucial contacts include both H-2Dd AND beta 2-microglobulin

scientific article published on 05 November 2001

CD28, costimulator or agonist receptor?

scientific article

CD300b regulates the phagocytosis of apoptotic cells via phosphatidylserine recognition.

scientific article

CD8 expression alters the fine specificity of an alloreactive MHC class I-specific T hybridoma

scientific article published in April 1992

Cell surface expression of an in vitro recombinant class II/class I major histocompatibility complex gene product

scientific article published on 01 February 1985

Chimeric anti-staphylococcal enterotoxin B antibodies and lovastatin act synergistically to provide in vivo protection against lethal doses of SEB.

scientific article

Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.

scientific article

Crystal structure of the Ly49I natural killer cell receptor reveals variability in dimerization mode within the Ly49 family

scientific article

Cutting Edge: Inhibition of the Interaction of NK Inhibitory Receptors with MHC Class I Augments Antiviral and Antitumor Immunity

scientific article published on 29 June 2020

Cutting antigenic peptides down to size

scientific article published on 01 December 2019

Different Vaccine Vectors Delivering the Same Antigen Elicit CD8+ T Cell Responses with Distinct Clonotype and Epitope Specificity

scientific article

Direct interaction of the mouse cytomegalovirus m152/gp40 immunoevasin with RAE-1 isoforms

scientific journal article

Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity.

scientific article published on 26 January 2018

Exon shuffling: mapping polymorphic determinants on hybrid mouse transplantation antigens

scientific article published in Nature

Failure of signaling through a chimeric class I-immunoglobulin molecule expressed on the surface of transfected B lymphoma cells and cells of transgenic mice

scientific article published on 01 August 1992

Functional cell surface expression by a recombinant single-chain class I major histocompatibility complex molecule with a cis-active beta 2-microglobulin domain

scientific article published on 01 November 1994

Functional expression of a transfected murine class II MHC gene

scientific article published in November 1983

H-2-like genes in the Tla region of mouse chromosome 17

scientific article published on 01 January 1982

Home schooling of NK cells

scientific article published in March 2009

How the virus outsmarts the host: function and structure of cytomegalovirus MHC-I-like molecules in the evasion of natural killer cell surveillance

scientific article

Immunochemical analysis of a recombinant, genetically engineered, secreted HLA-A2/Q10b fusion protein

scientific article published on October 1991

Immunology. An affinity for learning

scientific article published in June 1996

Inhibition of an allospecific T cell hybridoma by soluble class I proteins and peptides: estimation of the affinity of a T cell receptor for MHC

scientific article published on 01 January 1989

Interactions of TCRs with MHC-peptide complexes: a quantitative basis for mechanistic models

scientific article published on June 1997

Ly49A allelic variation and MHC class I specificity

scientific article published in September 2001

MHC class I recognition by Ly49 natural killer cell receptors.

scientific article

Minimal requirements for peptide mediated activation of CD8+ CTL.

scientific article published on November 1994

Molecular interactions: stiff or floppy (or somewhere in between?)

scientific article published on 01 December 2003

Peptide libraries define the fine specificity of anti-polysaccharide antibodies to Cryptococcus neoformans.

scientific article published on August 1996

Peptides tailored to perfection?

scientific article published on 01 April 1992

Phosphorylation of extracellular domains of T-lymphocyte surface proteins. Constitutive serine and threonine phosphorylation of the T cell antigen receptor ectodomains

scientific article published on October 1996

Post-thymectomy autoimmune gastritis: fine specificity and pathogenicity of anti-H/K ATPase-reactive T cells

scientific article published on February 1999

Potent neutralization of staphylococcal enterotoxin B by synergistic action of chimeric antibodies

scientific article

Resistance to viral infection by intraepithelial lymphocytes in HIV-1 P18-I10-specific T-cell receptor transgenic mice

scientific article published in April 2004

Role of alpha3 domain of class I MHC molecules in the activation of high- and low-avidity CD8+ CTLs.

scientific article published on November 2007

Role of conserved regions of class I MHC molecules in the activation of CD8+ cytotoxic T lymphocytes by peptide and purified cell-free class I molecules

scientific article published on 01 September 1993

Signals controlling alternative splicing of major histocompatibility complex H-2 class I pre-mRNA

scientific article published on 01 January 1988

Somatic cell hybridization of mouse myeloma cells

scientific article published on 01 July 1976

Split tolerance to the MHC class I molecule H-2Dd in animals transgenic for its soluble analog

scientific article published on 01 February 1997

Structural basis of MHC class I recognition by natural killer cell receptors

scientific journal article

Structure and function of murine cytomegalovirus MHC-I-like molecules: how the virus turned the host defense to its advantage.

scientific article published on January 2009

Structure and function of natural killer cell receptors: multiple molecular solutions to self, nonself discrimination.

scientific article

Studying interactions involving the T-cell antigen receptor by surface plasmon resonance

scientific article published on April 1996

T-cell recognition of a chimaeric class II/class I MHC molecule and the role of L3T4

scientific article published on 01 October 1985

TCR avidity: it's not how strong you make it, it's how you make it strong

scientific article published on 01 August 2001

The cellular environment regulates in situ kinetics of T-cell receptor interaction with peptide major histocompatibility complex

scientific article published on 22 May 2015

The in-betweeners: MAIT cells join the innate-like lymphocytes gang

scientific article

The lectin-like NK cell receptor Ly-49A recognizes a carbohydrate-independent epitope on its MHC class I ligand

scientific article published on 01 February 1998

The structure of mouse cytomegalovirus m04 protein obtained from sparse NMR data reveals a conserved fold of the m02-m06 viral immune modulator family

scientific article

Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b)

scientific article

bca: an activation-related B-cell gene ⬇️

scientific article published on January 1, 1998

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