List of works - Ian A. Prior

3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin

scientific article

A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging

scientific article

A comprehensive survey of Ras mutations in cancer

scientific article

A reliable method for attaching biological molecules to layer-by-layer self-assemblies

article

A simple method for preparing spectrally encoded magnetic beads for multiplexed detection

scientific article published in December 2007

Absolute Quantification of Endogenous Ras Isoform Abundance

scientific article published on 11 November 2015

Acrylate-Facilitated Cellular Uptake of Gold Nanoparticles

scientific article published on 07 June 2011

Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells

scientific article

C-terminal sequences in R-Ras are involved in integrin regulation and in plasma membrane microdomain distribution

scientific article published in November 2003

CD317/tetherin is an organiser of membrane microdomains

scientific article

Cathepsin L digestion of nanobioconjugates upon endocytosis

scientific article published in September 2009

Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane

scientific article published on 13 April 2003

Comparative proteomic analysis of compartmentalised Ras signalling

scientific article published on December 2015

Compartmentalized Ras signaling differentially contributes to phenotypic outputs

scientific article published on 22 May 2013

Compartmentalized signalling: Ras proteins and signalling nanoclusters.

scientific article published on 23 February 2009

Compartmentalized signalling: cAMP, calcium and Ras.

scientific article published on 23 February 2009

Concentric lamellae - novel microanatomical structures in the articular calcified cartilage of mice

scientific article published on 01 August 2019

Conserved effects and altered trafficking of Cetuximab antibodies conjugated to gold nanoparticles with precise control of their number and orientation

scientific article published on 27 April 2017

Control of growth factor receptor dynamics by reversible ubiquitination

scientific article

Decoding RAS isoform and codon-specific signalling.

scientific article

Detection of thiol modification following generation of reactive nitrogen species: analysis of synaptic vesicle proteins

article

Differential reprogramming of isogenic colorectal cancer cells by distinct activating KRAS mutations

scientific article

Direct visualization of Ras proteins in spatially distinct cell surface microdomains

scientific article

Docosahexaenoic acid alters the size and distribution of cell surface microdomains

scientific article published on 17 November 2007

ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions

scientific article published on 03 September 2019

Electron Microscopy Methods for Studying Plasma Membranes

scientific article published on 01 January 2015

Electron microscopic imaging of Ras signaling domains

scientific article published on October 2005

Eps8 is a convergence point integrating EGFR and integrin trafficking and crosstalk

Feedback activation of neurofibromin terminates growth factor-induced Ras activation.

scientific article published on 9 February 2016

Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation

scientific journal article

GTP-dependent segregation of H-ras from lipid rafts is required for biological activity

scientific article published on April 2001

Global snapshot of the influence of endocytosis upon EGF receptor signaling output.

scientific article

Glutamate uptake occurs at an early stage of synaptic vesicle recycling.

scientific article published in May 1997

Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling

scientific article

Inhibition of lipid raft-dependent signaling by a dystrophy-associated mutant of caveolin-3.

scientific article published on 7 March 2002

Intracellular mapping with SERS-encoded gold nanostars

scientific article published on 10 August 2011

LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells

scientific article published on 25 October 2019

Magnetic CoPt nanoparticles as MRI contrast agent for transplanted neural stem cells detection ⬇️

scientific article published on February 4, 2011

Microtubule organization within mitotic spindles revealed by serial block face scanning electron microscopy and image analysis

scientific article

Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release.

scientific article published on 12 July 2017

Modulating Protein-Protein Interactions of the Mitotic Polo-like Kinases to Target Mutant KRAS.

scientific article published on 27 July 2017

Negotiation of intracellular membrane barriers by TAT-modified gold nanoparticles

scientific article published on 31 May 2011

New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome

scientific article published on 18 December 2017

Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status

scientific article published on 13 August 2013

Palmitoylation and localisation of RAS isoforms are modulated by the hypervariable linker domain

scientific article published on 22 January 2008

Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells

scientific article

Plasma membrane microdomains: organization, function and trafficking

scientific article published on May 2004

Plasticity of mammary cell boundaries governed by EGF and actin remodeling

scientific article published on 18 September 2014

Pronounced in vivo hemoglobin polymerization in red blood cells of Gulf toadfish: a general role for hemoglobin aggregation in vertebrate hemoparasite defense?

scientific article published on 11 September 2013

Putting signalling into context

scientific article published on 01 March 2012

Quantification of spatiotemporal patterns of Ras isoform expression during development.

scientific article published on 24 January 2017

Quantitative Proteomic Analysis of Compartmentalized Signaling Networks

scientific article published on 01 January 2014

RAS variant signalling

scientific article published on 03 October 2018

Raft protein clustering alters N-Ras membrane interactions and activation pattern.

scientific article

Ras acylation, compartmentalization and signaling nanoclusters (Review).

scientific article published on 27 December 2008

Ras isoform abundance and signalling in human cancer cell lines.

scientific article published on 12 November 2007

Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling ⬇️

scientific article published on September 1, 2013

Ras proteins: paradigms for compartmentalised and isoform-specific signalling.

scientific article published on October 2007

Ras trafficking, localization and compartmentalized signalling ⬇️

scientific article published on September 8, 2011

Regulation of the cell cycle and centrosome biology by deubiquitylases

scientific article

Ribosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP(3) receptors.

scientific article published on 17 September 2009

S-nitrosylation of syntaxin 1 at Cys(145) is a regulatory switch controlling Munc18-1 binding

scientific article

Serial block-face scanning electron microscopy applied to study the trafficking of 8D3-coated gold nanoparticles at the blood-brain barrier

scientific article

Specific removal of TACC3/ch-TOG/clathrin at metaphase deregulates kinetochore fiber tension ⬇️

scientific article published on March 26, 2013

Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle

scientific article published on 20 November 2020

SuperCLEM: an accessible correlative light and electron microscopy approach for investigation of neurons and glia in vitro.

scientific article published on 30 May 2019

Targeting centrosome amplification, an Achilles' heel of cancer

scientific article published on 01 October 2019

The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity

scientific article published on 12 February 2018

The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-α1-antitrypsin

scientific article published on 06 September 2016

The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle.

scientific article published on 19 June 2015

The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression

scientific article published on 7 April 2014

The role of Ca2+ influx in endocytic vacuole formation in pancreatic acinar cells

scientific article

The role of palmitoylation in regulating Ras localization and function.

scientific article published on February 2013

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

scientific article

Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane

scientific article published on August 2004

Three-dimensional electron microscopic reconstruction of intracellular organellar arrangements in vascular smooth muscle--further evidence of nanospaces and contacts

scientific article

Traffic of Kv4 K+ channels mediated by KChIP1 is via a novel post-ER vesicular pathway

scientific article

Transport of fibroblast growth factor 2 in the pericellular matrix is controlled by the spatial distribution of its binding sites in heparan sulfate

scientific article (publication date: July 2012)

Trypanosoma brucei colonises the tsetse gut via an immature peritrophic matrix in the proventriculus: Supplementary data

Trypanosoma brucei colonizes the tsetse gut via an immature peritrophic matrix in the proventriculus

scientific article published on 20 April 2020

Ultrastructural examination of tissue in a patient with alkaptonuric arthropathy reveals a distinct pattern of binding of ochronotic pigment

scientific article published on 24 February 2010

Uptake and Intracellular Fate of Surface-Modified Gold Nanoparticles

scientific article published on 01 August 2008

Vpu and Tsg101 regulate intracellular targeting of the human immunodeficiency virus type 1 core protein precursor Pr55gag

scientific article published on April 2006

List of works by Ian A. Prior

3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin

A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging

A comprehensive survey of Ras mutations in cancer

A reliable method for attaching biological molecules to layer-by-layer self-assemblies

A simple method for preparing spectrally encoded magnetic beads for multiplexed detection

Absolute Quantification of Endogenous Ras Isoform Abundance

Acrylate-Facilitated Cellular Uptake of Gold Nanoparticles

Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells

C-terminal sequences in R-Ras are involved in integrin regulation and in plasma membrane microdomain distribution

CD317/tetherin is an organiser of membrane microdomains

Cathepsin L digestion of nanobioconjugates upon endocytosis

Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane

Comparative proteomic analysis of compartmentalised Ras signalling

Compartmentalized Ras signaling differentially contributes to phenotypic outputs

Compartmentalized signalling: Ras proteins and signalling nanoclusters.

Compartmentalized signalling: cAMP, calcium and Ras.

Concentric lamellae - novel microanatomical structures in the articular calcified cartilage of mice

Conserved effects and altered trafficking of Cetuximab antibodies conjugated to gold nanoparticles with precise control of their number and orientation

Control of growth factor receptor dynamics by reversible ubiquitination

Decoding RAS isoform and codon-specific signalling.

Detection of thiol modification following generation of reactive nitrogen species: analysis of synaptic vesicle proteins

Differential reprogramming of isogenic colorectal cancer cells by distinct activating KRAS mutations

Direct visualization of Ras proteins in spatially distinct cell surface microdomains

Docosahexaenoic acid alters the size and distribution of cell surface microdomains

ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions

Electron Microscopy Methods for Studying Plasma Membranes

Electron microscopic imaging of Ras signaling domains

Eps8 is a convergence point integrating EGFR and integrin trafficking and crosstalk

Feedback activation of neurofibromin terminates growth factor-induced Ras activation.

Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation

GTP-dependent segregation of H-ras from lipid rafts is required for biological activity

Global snapshot of the influence of endocytosis upon EGF receptor signaling output.

Glutamate uptake occurs at an early stage of synaptic vesicle recycling.

Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling

Inhibition of lipid raft-dependent signaling by a dystrophy-associated mutant of caveolin-3.

Intracellular mapping with SERS-encoded gold nanostars

LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells

Magnetic CoPt nanoparticles as MRI contrast agent for transplanted neural stem cells detection ⬇️

Microtubule organization within mitotic spindles revealed by serial block face scanning electron microscopy and image analysis

Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release.

Modulating Protein-Protein Interactions of the Mitotic Polo-like Kinases to Target Mutant KRAS.

Negotiation of intracellular membrane barriers by TAT-modified gold nanoparticles

New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome

Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status

Palmitoylation and localisation of RAS isoforms are modulated by the hypervariable linker domain

Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells

Plasma membrane microdomains: organization, function and trafficking

Plasticity of mammary cell boundaries governed by EGF and actin remodeling

Pronounced in vivo hemoglobin polymerization in red blood cells of Gulf toadfish: a general role for hemoglobin aggregation in vertebrate hemoparasite defense?

Putting signalling into context

Quantification of spatiotemporal patterns of Ras isoform expression during development.

Quantitative Proteomic Analysis of Compartmentalized Signaling Networks

RAS variant signalling

Raft protein clustering alters N-Ras membrane interactions and activation pattern.

Ras acylation, compartmentalization and signaling nanoclusters (Review).

Ras isoform abundance and signalling in human cancer cell lines.

Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling ⬇️

Ras proteins: paradigms for compartmentalised and isoform-specific signalling.

Ras trafficking, localization and compartmentalized signalling ⬇️

Regulation of the cell cycle and centrosome biology by deubiquitylases

Ribosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP(3) receptors.

S-nitrosylation of syntaxin 1 at Cys(145) is a regulatory switch controlling Munc18-1 binding

Serial block-face scanning electron microscopy applied to study the trafficking of 8D3-coated gold nanoparticles at the blood-brain barrier

Specific removal of TACC3/ch-TOG/clathrin at metaphase deregulates kinetochore fiber tension ⬇️

Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle

SuperCLEM: an accessible correlative light and electron microscopy approach for investigation of neurons and glia in vitro.

Targeting centrosome amplification, an Achilles' heel of cancer

The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity

The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-α1-antitrypsin

The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle.

The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression

The role of Ca2+ influx in endocytic vacuole formation in pancreatic acinar cells

The role of palmitoylation in regulating Ras localization and function.

The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation

Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane

Three-dimensional electron microscopic reconstruction of intracellular organellar arrangements in vascular smooth muscle--further evidence of nanospaces and contacts

Traffic of Kv4 K+ channels mediated by KChIP1 is via a novel post-ER vesicular pathway

Transport of fibroblast growth factor 2 in the pericellular matrix is controlled by the spatial distribution of its binding sites in heparan sulfate

Trypanosoma brucei colonises the tsetse gut via an immature peritrophic matrix in the proventriculus: Supplementary data